Hiroyasu Koga

Summary

Country: Japan

Publications

  1. ncbi request reprint [Animal model for superficial mycosis]
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, 345 Oyamada cho, Kawachi Nagano, Osaka, Japan
    Nihon Ishinkin Gakkai Zasshi 50:85-9. 2009
  2. pmc Short-term therapy with luliconazole, a novel topical antifungal imidazole, in guinea pig models of tinea corporis and tinea pedis
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, Kawachi Nagano, Osaka, Japan
    Antimicrob Agents Chemother 56:3138-43. 2012
  3. ncbi request reprint In vitro antifungal activity of luliconazole against clinical isolates from patients with dermatomycoses
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, 345 Oyamada cho, Kawachi Nagano, Osaka, 586 0094, Japan
    J Infect Chemother 12:163-5. 2006
  4. doi request reprint In vitro antifungal activities of luliconazole, a new topical imidazole
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, Kawachi Nagano, Osaka, Japan
    Med Mycol 47:640-7. 2009
  5. ncbi request reprint [In vitro activities of antifungal drugs against clinical isolates of Trichophyton tonsurans]
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, Osaka, Japan
    Nihon Ishinkin Gakkai Zasshi 47:299-304. 2006
  6. doi request reprint In vitro Antifungal Activity of Luliconazole against Trichophyton spp
    Jun Maeda
    Nihon Nohyaku Co, Ltd
    Med Mycol J 57:J1-6. 2016
  7. doi request reprint Affinity of Luliconazole to Keratin Prepared from Healthy Human Nailand Porcine Hoof
    Masayuki Hasuko
    Nihon Nohyaku Co, Ltd
    Med Mycol J 57:J7-J12. 2016
  8. pmc Spontaneous intraocular hemorrhage in rats during postnatal ocular development
    Katsuhiro Inagaki
    Research Center, Nihon Nohyaku, Kawachi Nagano, Osaka, Japan Laboratory of Veterinary Physiology, Nippon Veterinary and Life Science University, Musashino shi, Tokyo, Japan
    Comp Med 64:34-43. 2014
  9. doi request reprint Ligand-independent androgen receptor antagonism caused by the newly developed pesticide pyrifluquinazon (PFQ)
    Ryoko Yasunaga
    Research and Development Division, Nihon Nohyaku Co Ltd, 345 Oyamada cho, Kawachi Nagano, Osaka, Japan
    Reprod Toxicol 35:1-6. 2013

Collaborators

  • Hiroetsu Suzuki
  • Toshiro Majima
  • K Makimura
  • K Uchida
  • Jun Maeda
  • Ryoji Tsuboi
  • Tetsuo Toga
  • Masayuki Hasuko
  • Katsuhiro Inagaki
  • Kazuyoshi Inoue
  • Ryoko Yasunaga
  • Toshiya Tsunemitsu
  • Yasuko Nanjoh
  • Takahiro Matsumoto
  • Hirofumi Hirano
  • Katsushi Suzuki
  • Junko Ikuta
  • Hiroto Tamura
  • Takao Masaki
  • Yohei Murata

Detail Information

Publications9

  1. ncbi request reprint [Animal model for superficial mycosis]
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, 345 Oyamada cho, Kawachi Nagano, Osaka, Japan
    Nihon Ishinkin Gakkai Zasshi 50:85-9. 2009
    ..These models using guinea pigs were considered to be useful for studying the pathogenesis of, and evaluating therapies for, T. tonsurans infection and seborrhoeic dermatitis...
  2. pmc Short-term therapy with luliconazole, a novel topical antifungal imidazole, in guinea pig models of tinea corporis and tinea pedis
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, Kawachi Nagano, Osaka, Japan
    Antimicrob Agents Chemother 56:3138-43. 2012
    ..Luliconazole is expected to be useful in the clinical management of dermatophytosis...
  3. ncbi request reprint In vitro antifungal activity of luliconazole against clinical isolates from patients with dermatomycoses
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, 345 Oyamada cho, Kawachi Nagano, Osaka, 586 0094, Japan
    J Infect Chemother 12:163-5. 2006
    ..These results showed that luliconazole was very potent in vitro against pathogenic fungi isolated from patients with dermatomycoses, and these findings emphasized the utility of luliconazole for the topical management of this condition...
  4. doi request reprint In vitro antifungal activities of luliconazole, a new topical imidazole
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, Kawachi Nagano, Osaka, Japan
    Med Mycol 47:640-7. 2009
    ..004-0.016 microg/ml) suggesting action comparable to or stronger than that of ketoconazole. These results indicate a possible clinical role for luliconazole with its broad-spectrum antimycotic activity...
  5. ncbi request reprint [In vitro activities of antifungal drugs against clinical isolates of Trichophyton tonsurans]
    Hiroyasu Koga
    Research Center, Nihon Nohyaku Co, Ltd, Osaka, Japan
    Nihon Ishinkin Gakkai Zasshi 47:299-304. 2006
    ..mentagrophytes and T. rubrum, major causative agents of dermatomycosis. The results also demonstrated the strong antifungal activity of lanoconazole and luliconazole against T. tonsurans...
  6. doi request reprint In vitro Antifungal Activity of Luliconazole against Trichophyton spp
    Jun Maeda
    Nihon Nohyaku Co, Ltd
    Med Mycol J 57:J1-6. 2016
    ..In this study, we found that luliconazole had the most potent antifungal activity among the major topical antimycotics used in Japan and the US. Luliconazole would be the best-in-class drug for dermatophytosis in clinics. ..
  7. doi request reprint Affinity of Luliconazole to Keratin Prepared from Healthy Human Nailand Porcine Hoof
    Masayuki Hasuko
    Nihon Nohyaku Co, Ltd
    Med Mycol J 57:J7-J12. 2016
    ..The LLCZ delivered to the loci would exert its antifungal potential on tinea unguium. This study also suggests the versatility of porcine hoof powder as an alternative to human nail keratin preparation for non-clinical study. ..
  8. pmc Spontaneous intraocular hemorrhage in rats during postnatal ocular development
    Katsuhiro Inagaki
    Research Center, Nihon Nohyaku, Kawachi Nagano, Osaka, Japan Laboratory of Veterinary Physiology, Nippon Veterinary and Life Science University, Musashino shi, Tokyo, Japan
    Comp Med 64:34-43. 2014
    ..The mechanisms underlying hemorrhage in the retina and choroid remain unclear. To our knowledge, this report is the first to describe the spontaneous intraocular hemorrhage that occurs during postnatal ocular development in rats. ..
  9. doi request reprint Ligand-independent androgen receptor antagonism caused by the newly developed pesticide pyrifluquinazon (PFQ)
    Ryoko Yasunaga
    Research and Development Division, Nihon Nohyaku Co Ltd, 345 Oyamada cho, Kawachi Nagano, Osaka, Japan
    Reprod Toxicol 35:1-6. 2013
    ..Our findings should provide a novel insight into the regulation of AR-mediated transcription...