Masahiro Inoue

Summary

Affiliation: Kurume University School of Medicine
Country: Japan

Publications

  1. doi request reprint Identification and characterization of a cell division-regulating kinase AKB1 (associated kinase of Trypanosoma brucei 14-3-3) through proteomics study of the Tb14-3-3 binding proteins
    Masahiro Inoue
    Division of Eukaryotic Microbiology, Department of Infectious Medicine, Kurume University School of Medicine, 67 Asahi machi Kurume, Fukuoka 830 0011, Japan Department of Virology, Institute of Tropical Medicine, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan Department of Protozoology, Institute of Tropical Medicine, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan Fukuoka Tokushukai Medical Center, 4 5 Sugu kita, Kasuga, Fukuoka 816 0864, Japan Laboratory of Hygienic Chemistry, Daiichi University of Pharmacy, 22 1, Tamagawa cho, Minami Ku, Fukuoka 815 8511, Japan Department of Oncological Sciences, Experimental Therapeutics Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, Room 1520, New York, NY 10029, USA and Department of Radiation Oncology, Houston Methodist Research Institute, Weill Cornell Medical College, 6550 Fannin St
    J Biochem 158:49-60. 2015
  2. pmc Phosphorylation-dependent protein interaction with Trypanosoma brucei 14-3-3 proteins that display atypical target recognition
    Masahiro Inoue
    Division of Eukaryotic Microbiology, Department of Infectious Medicine, Kurume University School of Medicine, Kurume, Japan
    PLoS ONE 5:e15566. 2010
  3. ncbi request reprint The 14-3-3 proteins of Trypanosoma brucei function in motility, cytokinesis, and cell cycle
    Masahiro Inoue
    Department of Parasitology, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    J Biol Chem 280:14085-96. 2005
  4. doi request reprint Trypanosoma brucei 14-3-3I and II proteins predominantly form a heterodimer structure that acts as a potent cell cycle regulator in vivo
    Masahiro Inoue
    Department of Infectious Medicine, Division of Eukaryotic Microbiology, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    J Biochem 153:431-9. 2013
  5. doi request reprint Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase
    Yuji Horita
    Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan
    J Biol Chem 283:6013-21. 2008
  6. pmc Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid
    Ayako Uchiyama
    Department of Biology, Faculty of Science, Ochanomizu University, 2 1 1 Ohtsuka, Tokyo 112 8610, Japan
    Biochim Biophys Acta 1771:103-12. 2007
  7. ncbi request reprint Inhibition of transendothelial migration and invasion of human breast cancer cells by preventing geranylgeranylation of Rho
    Toshiyuki Kusama
    Department of Tumor Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537 8511, Japan kusama to mc pref osaka jp
    Int J Oncol 29:217-23. 2006
  8. ncbi request reprint CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer
    Dylan Daniel
    Department of Biochemistry, Diabetes Center and Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0534, USA
    Cancer Res 65:2018-25. 2005
  9. pmc An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
    Enrico Giraudo
    Department of Biochemistry and Biophysics, Diabetes Center, and Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA
    J Clin Invest 114:623-33. 2004
  10. ncbi request reprint Targeting hypoxic cancer cells with a protein prodrug is effective in experimental malignant ascites
    Masahiro Inoue
    Department of Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari ku, Osaka 537 8511, Japan
    Int J Oncol 25:713-20. 2004

Collaborators

  • Tatsuru Hara
  • Akihiko Tsuji
  • Yoshitatsu Sei
  • K Stuart
  • ACHIM C SCHNAUFER
  • W J Schneider
  • Mutsuko Mukai
  • Enrico Giraudo
  • Yuji Horita
  • Ayako Uchiyama
  • Toshiyuki Kusama
  • Dylan Daniel
  • Douglas Hanahan
  • Masaharu Tatsuta
  • Kousei Tanaga
  • Hiroyuki Nakamura
  • Shinae Kizaka-Kondoh
  • Yasuo Nakamura
  • Kensaku Mizuno
  • Kazumasa Ohashi
  • Susumu Kobayashi
  • Yuichiro Tanaka
  • Nobuyuki Kawai
  • Tamotsu Niki
  • Shigenori Enoki
  • Hiromu Murofushi
  • Kimiko Murakami-Murofushi
  • Yuko Fujiwara
  • Gabor Tigyi
  • Tetsuyuki Kobayashi
  • Lee A Mizzen
  • N Randall Chu
  • Christopher Chiu
  • Kazuo Takahashi
  • Yanjuan Zhu
  • Satoshi Hirayama
  • Hideaki Bujo
  • Tatsuro Kanaki
  • Yasushi Saito
  • Keiji Mikami
  • Hiroshi Kido
  • Hiroshi Harada
  • Yuushi Okumura
  • Mai Nishikawa
  • Mayumi Shiota
  • Masahiro Hiraoka
  • Seiji Arase
  • Fumio Imamura
  • Teruo Iwasaki
  • Tadanori Mammoto
  • Masako Ayaki
  • Atsushi Togawa

Detail Information

Publications14

  1. doi request reprint Identification and characterization of a cell division-regulating kinase AKB1 (associated kinase of Trypanosoma brucei 14-3-3) through proteomics study of the Tb14-3-3 binding proteins
    Masahiro Inoue
    Division of Eukaryotic Microbiology, Department of Infectious Medicine, Kurume University School of Medicine, 67 Asahi machi Kurume, Fukuoka 830 0011, Japan Department of Virology, Institute of Tropical Medicine, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan Department of Protozoology, Institute of Tropical Medicine, Nagasaki University, 1 12 4 Sakamoto, Nagasaki 852 8523, Japan Fukuoka Tokushukai Medical Center, 4 5 Sugu kita, Kasuga, Fukuoka 816 0864, Japan Laboratory of Hygienic Chemistry, Daiichi University of Pharmacy, 22 1, Tamagawa cho, Minami Ku, Fukuoka 815 8511, Japan Department of Oncological Sciences, Experimental Therapeutics Institute, Mount Sinai School of Medicine, 1425 Madison Avenue, Room 1520, New York, NY 10029, USA and Department of Radiation Oncology, Houston Methodist Research Institute, Weill Cornell Medical College, 6550 Fannin St
    J Biochem 158:49-60. 2015
    ..Taken together, these findings suggest that AKB1 might regulate cytokinesis and cell division by phosphorylating cytoskeleton-associated proteins. ..
  2. pmc Phosphorylation-dependent protein interaction with Trypanosoma brucei 14-3-3 proteins that display atypical target recognition
    Masahiro Inoue
    Division of Eukaryotic Microbiology, Department of Infectious Medicine, Kurume University School of Medicine, Kurume, Japan
    PLoS ONE 5:e15566. 2010
    ..In Trypanosoma brucei, 14-3-3I and II play pivotal roles in motility, cytokinesis and the cell cycle. However, none of the T. brucei 14-3-3 binding proteins have previously been documented...
  3. ncbi request reprint The 14-3-3 proteins of Trypanosoma brucei function in motility, cytokinesis, and cell cycle
    Masahiro Inoue
    Department of Parasitology, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    J Biol Chem 280:14085-96. 2005
    ..These findings indicate that the 14-3-3 proteins play important roles in cell motility, cytokinesis, and the cell cycle...
  4. doi request reprint Trypanosoma brucei 14-3-3I and II proteins predominantly form a heterodimer structure that acts as a potent cell cycle regulator in vivo
    Masahiro Inoue
    Department of Infectious Medicine, Division of Eukaryotic Microbiology, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Fukuoka 830 0011, Japan
    J Biochem 153:431-9. 2013
    ..These results suggest that heterodimers play more significant roles than homodimers not only in the maintenance of steady-state levels of the 14-3-3 proteins but also in the regulation of cytokinesis...
  5. doi request reprint Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase
    Yuji Horita
    Department of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, Sendai, Miyagi, Japan
    J Biol Chem 283:6013-21. 2008
    ....
  6. pmc Inhibition of transcellular tumor cell migration and metastasis by novel carba-derivatives of cyclic phosphatidic acid
    Ayako Uchiyama
    Department of Biology, Faculty of Science, Ochanomizu University, 2 1 1 Ohtsuka, Tokyo 112 8610, Japan
    Biochim Biophys Acta 1771:103-12. 2007
    ..The antimetastatic effect of carba-cPA was accompanied by the inhibition of RhoA activation and was not due to inhibition of the activation of LPA receptors...
  7. ncbi request reprint Inhibition of transendothelial migration and invasion of human breast cancer cells by preventing geranylgeranylation of Rho
    Toshiyuki Kusama
    Department of Tumor Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka 537 8511, Japan kusama to mc pref osaka jp
    Int J Oncol 29:217-23. 2006
    ..These results suggest that geranylgeranylation step of RhoA and RhoC could be a good therapeutic target for the prevention of invasion and metastasis of breast cancer cells...
  8. ncbi request reprint CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer
    Dylan Daniel
    Department of Biochemistry, Diabetes Center and Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143 0534, USA
    Cancer Res 65:2018-25. 2005
    ..Thus, an HPV16 E7 immunogen holds promise for noninvasive treatment and prevention of human cervical cancer...
  9. pmc An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis
    Enrico Giraudo
    Department of Biochemistry and Biophysics, Diabetes Center, and Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA
    J Clin Invest 114:623-33. 2004
    ....
  10. ncbi request reprint Targeting hypoxic cancer cells with a protein prodrug is effective in experimental malignant ascites
    Masahiro Inoue
    Department of Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, Higashinari ku, Osaka 537 8511, Japan
    Int J Oncol 25:713-20. 2004
    ..Thus, TOP3 had a dramatic effect on malignant ascites and, hence, we propose that rodent malignant ascites is an appropriate platform for testing hypoxia-targeted drugs...
  11. ncbi request reprint LRP1B attenuates the migration of smooth muscle cells by reducing membrane localization of urokinase and PDGF receptors
    Kousei Tanaga
    Department of Clinical Cell Biology, Chiba University Graduate School of Medicine, Chiba, Japan
    Arterioscler Thromb Vasc Biol 24:1422-8. 2004
    ....
  12. ncbi request reprint Tumor hypoxia: a target for selective cancer therapy
    Shinae Kizaka-Kondoh
    Department of Molecular Oncology, Kyoto University Graduate School of Medicine, 54 Shongoin Kawahararcho, Sakyo ku, Kyoto 606 8507
    Cancer Sci 94:1021-8. 2003
    ..These approaches include our work with a unique hypoxia-targeting protein drug, TOP3, with which we have sought to address the above three difficulties...
  13. ncbi request reprint Cloning, expression analysis, and tissue distribution of esp-1/testisin, a membrane-type serine protease from the rat
    Yasuo Nakamura
    Department of Dermatology, The University of Tokushima School of Medicine, Tokushima, Japan
    J Med Invest 50:78-86. 2003
    ..This different distribution profile suggests that Esp-1/Testisin plays a role in species-specific proteolytic events during spermatogenesis and fertilization...
  14. ncbi request reprint Sustained tyrosine-phosphorylation of FAK through Rho-dependent adhesion to fibronectin is essential for cancer cell migration
    Mutsuko Mukai
    Department of Tumor Biochemistry, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1 3 3 Nakamichi, Higashinari ku, Osaka 537 8511, Japan
    Anticancer Res 22:3175-84. 2002
    ..Co-stimulation with lysophosphatidic acid (LPA) and fibronectin (FN) is essential for migration of rat ascites hepatoma MMI cells. We examined the roles of LPA and FN in Rho-FAK pathway to migration...