H Koga

Summary

Affiliation: Kurume University School of Medicine
Country: Japan

Publications

  1. doi request reprint Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1.
    Yu Ikezono
    Mol Cancer Res 15:744-752. 2017
  2. doi request reprint Probiotics promote rapid-turnover protein production by restoring gut flora in patients with alcoholic liver cirrhosis
    Hironori Koga
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, 830 0011, Japan
    Hepatol Int 7:767-74. 2013
  3. doi request reprint PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells
    Hironori Koga
    Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Int J Oncol 40:679-85. 2012
  4. ncbi request reprint Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation
    H Koga
    Second Department of Medicine, Kurume University Research Center for Innovative Cancer Therapy, Kurume, Japan
    Hepatology 29:688-96. 1999
  5. ncbi request reprint Hepatocellular carcinoma: is there a potential for chemoprevention using cyclooxygenase-2 inhibitors?
    Hironori Koga
    Second Department of Medicine, and Kurume University Research Center for Innovative Cancer Therapy, Kurume University, Kurume, Japan
    Cancer 98:661-7. 2003
  6. ncbi request reprint Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells
    Hironori Koga
    Second Department of Medicine and Research Center for Innovative Cancer Therapy, Kurume University, Japan
    Hepatology 37:1086-96. 2003
  7. ncbi request reprint Abnormal accumulation in lipopolysaccharide in biliary epithelial cells of rats with self-filling blind loop
    Hironori Koga
    Second Department of Medicine, Kurume University School of Medicine, 830 0011, Japan
    Int J Mol Med 9:621-6. 2002
  8. ncbi request reprint Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines
    H Koga
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Hepatology 33:1087-97. 2001
  9. ncbi request reprint Copper does not alter the intracellular distribution of ATP7B, a copper-transporting ATPase
    M Harada
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Biochem Biophys Res Commun 275:871-6. 2000
  10. doi request reprint Pigment epithelium-derived factor (PEDF) ameliorates advanced glycation end product (AGE)-induced hepatic insulin resistance in vitro by suppressing Rac-1 activation
    T Yoshida
    Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Horm Metab Res 40:620-5. 2008

Collaborators

Detail Information

Publications51

  1. doi request reprint Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1.
    Yu Ikezono
    Mol Cancer Res 15:744-752. 2017
    ..Mol Cancer Res; 15(6); 744-52. ©2017 AACR...
  2. doi request reprint Probiotics promote rapid-turnover protein production by restoring gut flora in patients with alcoholic liver cirrhosis
    Hironori Koga
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, 830 0011, Japan
    Hepatol Int 7:767-74. 2013
    ....
  3. doi request reprint PPARγ potentiates anticancer effects of gemcitabine on human pancreatic cancer cells
    Hironori Koga
    Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Int J Oncol 40:679-85. 2012
    ..Since Pio is widely used in the treatment of diabetes mellitus, it may become a feasible partner of Gem-based chemotherapy, fine-tuning the strength of the therapy in a dosage-dependent fashion...
  4. ncbi request reprint Expression of cyclooxygenase-2 in human hepatocellular carcinoma: relevance to tumor dedifferentiation
    H Koga
    Second Department of Medicine, Kurume University Research Center for Innovative Cancer Therapy, Kurume, Japan
    Hepatology 29:688-96. 1999
    ..These findings suggested that COX-2 may play a role in the early stages of hepatocarcinogenesis, but not in the advanced stages, and may consequently be related to HCC dedifferentiation...
  5. ncbi request reprint Hepatocellular carcinoma: is there a potential for chemoprevention using cyclooxygenase-2 inhibitors?
    Hironori Koga
    Second Department of Medicine, and Kurume University Research Center for Innovative Cancer Therapy, Kurume University, Kurume, Japan
    Cancer 98:661-7. 2003
    ..This hypothesis should be confirmed in in vivo studies using animal models. These studies may provide insights into any application of the COX-2 inhibitor for primary and/or secondary chemoprevention...
  6. ncbi request reprint Troglitazone induces p27Kip1-associated cell-cycle arrest through down-regulating Skp2 in human hepatoma cells
    Hironori Koga
    Second Department of Medicine and Research Center for Innovative Cancer Therapy, Kurume University, Japan
    Hepatology 37:1086-96. 2003
    ..In conclusion, troglitazone attenuated Skp2 expression, thereby promoting p27(Kip1) accumulation in human hepatoma cells. This therapeutic potential of the ligand may lead to new cell-cycle-based antitumor strategies for advanced HCCs...
  7. ncbi request reprint Abnormal accumulation in lipopolysaccharide in biliary epithelial cells of rats with self-filling blind loop
    Hironori Koga
    Second Department of Medicine, Kurume University School of Medicine, 830 0011, Japan
    Int J Mol Med 9:621-6. 2002
    ..These findings suggested that abnormal accumulation of LPS, which may be derived from portal blood, in BECs was involved in the pathogenesis of hepatobiliary inflammation with intestinal injury...
  8. ncbi request reprint Involvement of p21(WAF1/Cip1), p27(Kip1), and p18(INK4c) in troglitazone-induced cell-cycle arrest in human hepatoma cell lines
    H Koga
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Hepatology 33:1087-97. 2001
    ..These findings suggested that p21, p27, and p18 might be involved in troglitazone-induced cell-cycle arrest in human hepatoma cells...
  9. ncbi request reprint Copper does not alter the intracellular distribution of ATP7B, a copper-transporting ATPase
    M Harada
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Biochem Biophys Res Commun 275:871-6. 2000
    ..ATP7B seems to translocate copper from the cytosol to the late endosomal lumen, thus participating in biliary copper excretion via lysosomes...
  10. doi request reprint Pigment epithelium-derived factor (PEDF) ameliorates advanced glycation end product (AGE)-induced hepatic insulin resistance in vitro by suppressing Rac-1 activation
    T Yoshida
    Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Horm Metab Res 40:620-5. 2008
    ..PEDF may play a protective role against hepatic insulin resistance in diabetes...
  11. ncbi request reprint Relation of type II transforming growth factor-beta receptor to hepatic fibrosis and hepatocellular carcinoma
    T Ueno
    Kurume University Research Center for Innovative Cancer Therapy, Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Int J Oncol 18:49-55. 2001
    ..This may provide a selective growth advantage to HCC to escape the inhibitory growth signals of TGF-beta1, and may be linked with critical steps in the growth of hepatoma cells...
  12. ncbi request reprint A mutation of the Wilson disease protein, ATP7B, is degraded in the proteasomes and forms protein aggregates
    M Harada
    Second Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Gastroenterology 120:967-74. 2001
    ..These aggresomes were similar to Mallory bodies on electron microscopy. CONCLUSIONS: The different protein properties of ATP7B mutants may explain the variety of clinical spectrums in patients with Wilson disease...
  13. doi request reprint Summary of results of serological tests and diagnoses for 4774 cases of various autoimmune bullous diseases consulted to Kurume University
    T Hashimoto
    Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, Kurume, Fukuoka, 830 0011, Japan
    Br J Dermatol 175:953-965. 2016
    ..Although many new disease entities of autoimmune bullous disease (AIBD) have recently been recognized, satisfactory immunological diagnostic methods and comprehensive classifications for various AIBDs have not been established...
  14. doi request reprint Clinical and immunological findings in 104 cases of paraneoplastic pemphigus
    A Ohzono
    Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, 67 Asahimachi, Kurume, Fukuoka, 830 0011, Japan
    Br J Dermatol 173:1447-52. 2015
    ..Although there are many reports of sporadic patients with paraneoplastic pemphigus (PNP), only a few systematic studies on large cohorts of patients with PNP have been reported...
  15. ncbi request reprint Budd-Chiari syndrome complicated by hepatocellular carcinoma with no evidence of infection with hepatitis virus: a case report
    T Kawaguchi
    Second Department of Medicine, Kurume University School of Medicine, Japan
    Hepatogastroenterology 46:3237-40. 1999
    ..This case suggests that chronic venous congestion of the liver may be one of the pathologic conditions that occurs in hepatocellular carcinoma...
  16. doi request reprint Clinical and immunological profiles in 17 Japanese patients with drug-induced pemphigus studied at Kurume University
    K Yoshimura
    Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, 67 Asahimachi, Kurume, Fukuoka, 830 0011, Japan
    Br J Dermatol 171:544-53. 2014
    ..Drug-induced pemphigus (DIP) shows clinical, histopathological and immunological features of pemphigus. However, little is known about immunological profiles in DIP...
  17. ncbi request reprint Telmisartan inhibits AGE-induced C-reactive protein production through downregulation of the receptor for AGE via peroxisome proliferator-activated receptor-gamma activation
    T Yoshida
    Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume, Japan
    Diabetologia 49:3094-9. 2006
    ....
  18. pmc Biliary secretion of endotoxin and pathogenesis of primary biliary cirrhosis
    S Sakisaka
    Second Department of Medicine, Kurume University School of Medicine, Japan
    Yale J Biol Med 70:403-8. 1997
    ..These results suggest that, in biliary epithelial cells, retention of endotoxin, increased apoptosis, and increased permeability of tight junctions may be involved in the pathogenesis of PBC...
  19. ncbi request reprint Spreds, inhibitors of the Ras/ERK signal transduction, are dysregulated in human hepatocellular carcinoma and linked to the malignant phenotype of tumors
    T Yoshida
    Department of Medicine, Kurume University School of Medicine, Liver Cancer Division, Research Center for Innovative Cancer Therapy, and Center of the 21st Century COE Program for Medical Science, Kurume, Japan
    Oncogene 25:6056-66. 2006
    ..These data indicate that the reduction of Spred expression in HCC is one of the causes of the acquisition of malignant features. Thus, Spred could be not only a novel prognostic factor but also a new therapeutic target for human HCC...
  20. doi request reprint Efficacy and safety of rituximab treatment in Indian pemphigus patients
    A J Kanwar
    Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    J Eur Acad Dermatol Venereol 27:e17-23. 2013
    ..Various treatment modalities have been described to treat pemphigus. In cases where the disease fails to respond to conventional therapy, rituximab has been shown to be effective...
  21. doi request reprint Anti-desmocollin autoantibodies in nonclassical pemphigus
    N Ishii
    Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, 67 Asahimachi, Kurume, Fukuoka, 830 0011, Japan
    Br J Dermatol 173:59-68. 2015
    ..No consistent immunoassay for immunoglobulin (Ig) G autoantibodies to Dscs has been developed...
  22. doi request reprint A clinical and serological study of linear IgA bullous dermatosis without linear immunoglobulin deposition other than IgA at the basement membrane zone in direct immunofluorescence
    C Ohata
    Department of Dermatology, Kurume University School of Medicine, Kurume, Japan
    Br J Dermatol . 2016
    ..Linear IgA bullous dermatosis (LABD) is a heterogeneous disease. Different diagnostic criteria have been used in different reports...
  23. doi request reprint Clinical and immunological profiles of 25 patients with pemphigoid gestationis
    N Tani
    Department of Dermatology, Kurume University School of Medicine, and Kurume University Institute of Cutaneous Cell Biology, 67 Asahimachi, Kurume, Fukuoka, 830 0011, Japan
    Br J Dermatol 172:120-9. 2015
    ..Systematic study of pemphigoid gestationis (PG) has not been performed owing to its rarity...
  24. doi request reprint Immunoglobulin G deposition to nonhemidesmosomal lamina lucida and early neutrophil involvement are characteristic features in a case of anti-p200 pemphigoid
    A Shimizu
    Department of Dermatology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku, Tokyo 160 8582, Japan
    Br J Dermatol 168:647-55. 2013
    ....
  25. doi request reprint Five Japanese cases of antidesmoglein 1 antibody-positive and antidesmoglein 3 antibody-negative pemphigus with oral lesions
    H Koga
    Department of Dermatology, Kurume University School of Medicine, Fukuoka, Japan
    Br J Dermatol 166:976-80. 2012
    ....
  26. ncbi request reprint Necessity of repeat biopsies in men for suspected prostate cancer
    M Noguchi
    Department of Urology, Kurume University School of Medicine, Japan
    Int J Urol 6:7-12. 1999
    ..The indications for repeat prostate needle biopsy in men whose initial biopsy results revealed no evidence of cancer are not defined...
  27. doi request reprint Mutation in keratin 18 induces mitochondrial fragmentation in liver-derived epithelial cells
    Hiroto Kumemura
    Division of Gastroenterology, Department of Medicine and Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Biochem Biophys Res Commun 367:33-40. 2008
    ..These findings suggest that the IFs are important for the maintenance of normal mitochondrial structures...
  28. ncbi request reprint Expression of uncoupling protein-2 in biliary epithelial cells in primary biliary cirrhosis
    Eitaro Taniguchi
    Second Department of Medicine and Kurume University Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Japan
    Liver 22:451-8. 2002
    ..However, uncoupling protein-2 expression in human liver has not been examined...
  29. ncbi request reprint Hydrogen peroxide overproduction in megamitochondria of troglitazone-treated human hepatocytes
    Shoichiro Shishido
    Second Department of Medicine, and the Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Japan
    Hepatology 37:136-47. 2003
    ..In conclusion, troglitazone caused overproduction of hydrogen peroxide, which deteriorated both mitochondrial membrane structures and mitochondrial function, leading to a possible priming for the severe hepatocyte toxicity...
  30. ncbi request reprint Wilson disease protein ATP7B is localized in the late endosomes in a polarized human hepatocyte cell line
    Masaru Harada
    Second Department of Medicine, Kurume University School of Medicine, Kurume 830 0011, Japan
    Int J Mol Med 11:293-8. 2003
    ..We believe that the disturbed incorporation of copper into the late endosomes caused by mutated ATP7B is the main defect in Wilson disease...
  31. ncbi request reprint Tumor necrosis factor-alpha and interferon-gamma directly impair epithelial barrier function in cultured mouse cholangiocytes
    Shinichiro Hanada
    Second Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Liver Int 23:3-11. 2003
    ..Moreover, we examined the inhibitory effect of ursodeoxycholic acid (UDCA) on cytokine-induced changes in paracellular permeability...
  32. ncbi request reprint Inhibition of proteasome-dependent degradation of Wee1 in G2-arrested Hep3B cells by TGF beta 1
    Osamu Hashimoto
    Liver Cancer Research Division, Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Japan
    Mol Carcinog 36:171-82. 2003
    ..These findings suggest that TGF beta 1 induced G2 arrest in Hep3B at least in part through stabilization of Wee1 and subsequent increase in Tyr-15 phosphorylation and inhibition of CDC2...
  33. ncbi request reprint [A case of drug induced liver injury related pioglitazone]
    Akiko Hisamochi
    Second Department of Medicine, Kurume University School of Medicine
    Nihon Shokakibyo Gakkai Zasshi 100:333-6. 2003
  34. ncbi request reprint Hepatocellular carcinoma with a "nodule-in-nodule" appearance reflecting an unusual dilated pseudoglandular structure
    Yusuke Ishida
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Karume, Japan
    Intern Med 47:1215-8. 2008
    ..It should be noted that there is a rare HCC with dilated pseudoglandular structure showing the inversed "nodule-in-nodule" appearance...
  35. pmc Hepatitis C virus down-regulates insulin receptor substrates 1 and 2 through up-regulation of suppressor of cytokine signaling 3
    Takumi Kawaguchi
    Second Department of Medicine, Kurume University School of Medicine 67 Asahi machi, Kurume 830 0011, Japan
    Am J Pathol 165:1499-508. 2004
    ..In conclusion, HCV infection changes a subset of hepatic molecules regulating glucose metabolism. A possible mechanism is that HCV core-induced SOCS3 promotes proteosomal degradation of IRS1 and IRS2 through ubiquitination...
  36. ncbi request reprint Serum C-reactive protein levels predict survival in hepatocellular carcinoma
    Sakae Nagaoka
    Department of Medicine, Division of Gastroenterology, Kurume University School of Medicine, Kurume, Japan
    Liver Int 27:1091-7. 2007
    ..We investigated the relationship between the serum levels of high sensitivity CRP (H-CRP) and the prognosis of HCC patients...
  37. ncbi request reprint Significance of glucose intolerance and SHIP2 expression in hepatocellular carcinoma patients with HCV infection
    Shuji Sumie
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Fukuoka 830 0011, Japan
    Oncol Rep 18:545-52. 2007
    ..In conclusion, this study is the first to demonstrate the significance of glucose intolerance in prognosis of male HCC patients and down-regulation of SHIP2 expression in HCC...
  38. ncbi request reprint Oxidative stress induces the endoplasmic reticulum stress and facilitates inclusion formation in cultured cells
    Shinichiro Hanada
    Department of Medicine, Kurume University School of Medicine, and Research Center for Innovative Cancer Therapy, and Center of the 21st Century COE Program for Medical Science, Kurume University, Kurume, Japan
    J Hepatol 47:93-102. 2007
    ..The endoplasmic reticulum (ER) is the organelle responsible for proper folding and elimination of unfolded proteins. Therefore, failure of this function increases defective proteins in the cell...
  39. ncbi request reprint Clearance of HCV improves insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate 1 and 2
    Takumi Kawaguchi
    Department of Digestive Disease Information and Research, Kurume University School of Medicine, Kurume, Japan
    Am J Gastroenterol 102:570-6. 2007
    ..The aim of this study is to examine the effects of clearance of HCV on insulin resistance, beta-cell function, and hepatic expression of insulin receptor substrate (IRS)1/2, central molecules for insulin signaling...
  40. pmc Cell cycle regulation by the Wee1 inhibitor PD0166285, pyrido [2,3-d] pyimidine, in the B16 mouse melanoma cell line
    Osamu Hashimoto
    Liver Cancer Division, Research Center for innovatve cancer therapy and Center of the 21st century COE program for medical Science, Kurume University, Kurume, Japan
    BMC Cancer 6:292. 2006
    ..The deregulated cell cycle progression may have ultimately damaged the cancer cells. We herein report one of the mechanism by which PD0166285 leads to cell death in the B16 mouse melanoma cell line...
  41. ncbi request reprint Proteasome inhibition induces inclusion bodies associated with intermediate filaments and fragmentation of the Golgi apparatus
    Masaru Harada
    Second Department of Medicine and Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Exp Cell Res 288:60-9. 2003
    ..The IF inclusions disappeared by restoring proteasome function, and autophagy and lysosomal degradation might be, at least in part, associated with the elimination of inclusion bodies...
  42. ncbi request reprint Value of fusing PET plus CT images in hepatocellular carcinoma and combined hepatocellular and cholangiocarcinoma patients with extrahepatic metastases: preliminary findings
    Sakae Nagaoka
    Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan
    Liver Int 26:781-8. 2006
    ....
  43. ncbi request reprint Prognostic significance of the F-box protein Skp2 expression in diffuse large B-cell lymphoma
    Ritsuko Seki
    Second Department of Internal Medicine, Kurume University School of Medicine, Fukuoka, Japan
    Am J Hematol 73:230-5. 2003
    ..The p27 expression level did not correlate patients' prognosis. Taken together, it was suggested that Skp2 was a valuable and independent marker predicting the outcome in DLBCL...
  44. ncbi request reprint Luteolin promotes degradation in signal transducer and activator of transcription 3 in human hepatoma cells: an implication for the antitumor potential of flavonoids
    Karuppaiyah Selvendiran
    Research Center for Innovative Cancer Therapy, and Center of the 21st Century Center of Excellence Program for Medical Science, Kurume University, Kurume, Japan
    Cancer Res 66:4826-34. 2006
    ....
  45. ncbi request reprint Endothelial progenitor cell transplantation improves the survival following liver injury in mice
    Eitaro Taniguchi
    Second Department of Medicine, Kurume University School of Medicine, Liver Cancer Division, Research Center for Innovative Cancer Therapy of the 21st Century COE Program for Medical Science, Japan
    Gastroenterology 130:521-31. 2006
    ..The aim of this study was to clarify the possible roles of endothelial progenitor cells during postnatal liver regeneration...
  46. ncbi request reprint Keratin-containing inclusions affect cell morphology and distribution of cytosolic cellular components
    Shinichiro Hanada
    Second Department of Medicine, Kurume University School of Medicine, Liver Cancer Division, Research Center for Innovative Cancer Therapy, Kurume University, 67 Asahi Machi, Kurume 830 0011, Japan jp
    Exp Cell Res 304:471-82. 2005
    ..01) and sometimes their morphology was significantly altered. Our data indicate that CK aggregates affect not only cell morphology but also the localization of various cytosolic components, which may affect the cellular function...
  47. ncbi request reprint Cholestasis in a rat model of graft-versus-host disease is accompanied by alteration of the expression and distribution of tight-junction-associated proteins
    Kurumi Sasatomi
    Second Department of Medicine, Kurume University School of Medicine, Japan
    Int J Mol Med 15:431-6. 2005
    ..Changes in TJ-associated proteins of both hepatocytes and BECs may reflect the immunopathogenesis of GVHD-associated intrahepatic cholestasis...
  48. pmc The Wilson disease protein ATP7B resides in the late endosomes with Rab7 and the Niemann-Pick C1 protein
    Masaru Harada
    Second Department of Medicine, Kurume University School of Medicine, 67 Asahi Machi, Kurume 830 0011, Japan
    Am J Pathol 166:499-510. 2005
    ..Thus, defective copper ATPase activity of ATP7B in the late endosomes appears to be the main defect of Wilson disease...
  49. ncbi request reprint Epichloë endophytes grow by intercalary hyphal extension in elongating grass leaves
    Michael J Christensen
    AgResearch, Grasslands Research Centre, Private Bag 11 008, Palmerston North 4442, New Zealand
    Fungal Genet Biol 45:84-93. 2008
    ..A new model describing the colonization of grasses by clavicipitaceous endophytes is described...
  50. doi request reprint Effects of hyperglycemia and insulin therapy on high mobility group box 1 in endotoxin-induced acute lung injury in a rat model
    Satoshi Hagiwara
    Department of Brain and Nerve Science, Anesthesiology, Oita University Faculty of Medicine, Oita, Japan
    Crit Care Med 36:2407-13. 2008
    ....
  51. ncbi request reprint Prophylactic lamivudine administration prevents exacerbation of liver damage in HBe antigen positive patients with hepatocellular carcinoma undergoing transhepatic arterial infusion chemotherapy
    Hiroaki Nagamatsu
    Second Department of Medicine, Kurume University School of Medicine, 830 0011 Kurume, Japan
    Am J Gastroenterol 99:2369-75. 2004
    ..In the present study, we investigated the effect of lamivudine administration for exacerbation of liver damage in such patients...