Kunio Kitamura

Summary

Affiliation: Mitsubishi Kagaku Institute of Life Sciences
Country: Japan

Publications

  1. ncbi Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation
    K Kitamura
    Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan
    Mech Dev 67:83-96. 1997
  2. ncbi Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans
    Kunio Kitamura
    Mitsubishi Kagaku Institute of Life Sciences, 11 Minamiooya, Machida, Tokyo 194 8511, Japan
    Nat Genet 32:359-69. 2002
  3. ncbi Arx homeobox gene is essential for development of mouse olfactory system
    Sei Ichi Yoshihara
    Laboratory for Neurobiology of Synapse, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    Development 132:751-62. 2005
  4. ncbi Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism
    K Kitamura
    Mitsubishi Kasei Institute of Life Sciences, Machida, Tokyo 194 8511, Japan
    Development 126:5749-58. 1999
  5. doi Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice
    Kunio Kitamura
    Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan
    Hum Mol Genet 18:3708-24. 2009
  6. ncbi Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation
    Mitsuhiro Kato
    Department of Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA
    Hum Mutat 23:147-59. 2004
  7. ncbi Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously
    Tsutomu Hirata
    Laboratory for Vertebrate Axis Formation, Center for Developmental Biology, RIKEN, Kobe 650 0047, Japan
    Development 133:1433-43. 2006
  8. ncbi Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteins
    Makoto Hayashi
    Department of Biochemistry, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 10 6 Ariake, Koto ku, Tokyo 135 8550, Japan
    J Biol Chem 283:565-71. 2008
  9. ncbi Prognostic significance of T-cell or cytotoxic molecules phenotype in classical Hodgkin's lymphoma: a clinicopathologic study
    Naoko Asano
    Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan
    J Clin Oncol 24:4626-33. 2006
  10. ncbi Alterations in mRNA expression of myelin proteins in the sciatic nerves and brains of streptozotocin-induced diabetic rats
    Rei Kawashima
    Department of Biochemistry, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara shi, Kanagawa, Japan
    Neurochem Res 32:1002-10. 2007

Collaborators

Detail Information

Publications11

  1. ncbi Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation
    K Kitamura
    Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan
    Mech Dev 67:83-96. 1997
    ..Each homeobox gene was also expressed regionally in the nucleus, suggesting that the nucleus is comprised of subdivisions...
  2. ncbi Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans
    Kunio Kitamura
    Mitsubishi Kagaku Institute of Life Sciences, 11 Minamiooya, Machida, Tokyo 194 8511, Japan
    Nat Genet 32:359-69. 2002
    ..The present report is, to our knowledge, the first to use phenotypic analysis of a knockout mouse to identify a gene associated with an X-linked human brain malformation...
  3. ncbi Arx homeobox gene is essential for development of mouse olfactory system
    Sei Ichi Yoshihara
    Laboratory for Neurobiology of Synapse, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
    Development 132:751-62. 2005
    ..These findings suggest a likely role of Arx in regulating the expression of putative instructive signals produced in the olfactory bulb for the proper innervation of olfactory sensory axons...
  4. ncbi Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerism
    K Kitamura
    Mitsubishi Kasei Institute of Life Sciences, Machida, Tokyo 194 8511, Japan
    Development 126:5749-58. 1999
    ....
  5. doi Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in mice
    Kunio Kitamura
    Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan
    Hum Mol Genet 18:3708-24. 2009
    ....
  6. ncbi Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlation
    Mitsuhiro Kato
    Department of Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA
    Hum Mutat 23:147-59. 2004
    ....
  7. ncbi Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously
    Tsutomu Hirata
    Laboratory for Vertebrate Axis Formation, Center for Developmental Biology, RIKEN, Kobe 650 0047, Japan
    Development 133:1433-43. 2006
    ..These findings suggest that signals from olfactory sensory neurons contribute to the proper formation of the olfactory bulb...
  8. ncbi Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteins
    Makoto Hayashi
    Department of Biochemistry, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 10 6 Ariake, Koto ku, Tokyo 135 8550, Japan
    J Biol Chem 283:565-71. 2008
    ..These findings suggest that Pitx2 suppresses osteogenic signals induced by BMPs in myoblasts to prevent their osteoblastic conversion...
  9. ncbi Prognostic significance of T-cell or cytotoxic molecules phenotype in classical Hodgkin's lymphoma: a clinicopathologic study
    Naoko Asano
    Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan
    J Clin Oncol 24:4626-33. 2006
    ..The aim of this study was to clarify the association between phenotypic expression and clinical outcome in CHL...
  10. ncbi Alterations in mRNA expression of myelin proteins in the sciatic nerves and brains of streptozotocin-induced diabetic rats
    Rei Kawashima
    Department of Biochemistry, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara shi, Kanagawa, Japan
    Neurochem Res 32:1002-10. 2007
    ..Considering the functional significance of myelin proteins, this impairment of protein expression is possibly involved in the pathogenesis of diabetic neuropathy, including that in brain disorders...
  11. ncbi BMI-1 is highly expressed in M0-subtype acute myeloid leukemia
    Masashi Sawa
    Department of Molecular Medicine and Hematology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Int J Hematol 82:42-7. 2005
    ..These results indicated that a subgroup of M0 patients has a high expression level of polycomb group gene BMI-1, which may contribute to leukemogenesis...