Genomes and Genes
Affiliation: Mitsubishi Kagaku Institute of Life Sciences
- Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formationK Kitamura
Mitsubishi Kasei Institute of Life Sciences, Tokyo, Japan
Mech Dev 67:83-96. 1997..Each homeobox gene was also expressed regionally in the nucleus, suggesting that the nucleus is comprised of subdivisions...
- Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humansKunio Kitamura
Mitsubishi Kagaku Institute of Life Sciences, 11 Minamiooya, Machida, Tokyo 194 8511, Japan
Nat Genet 32:359-69. 2002..The present report is, to our knowledge, the first to use phenotypic analysis of a knockout mouse to identify a gene associated with an X-linked human brain malformation...
- Arx homeobox gene is essential for development of mouse olfactory systemSei Ichi Yoshihara
Laboratory for Neurobiology of Synapse, RIKEN Brain Science Institute, Wako Shi, Saitama 351 0198, Japan
Development 132:751-62. 2005..These findings suggest a likely role of Arx in regulating the expression of putative instructive signals produced in the olfactory bulb for the proper innervation of olfactory sensory axons...
- Mouse Pitx2 deficiency leads to anomalies of the ventral body wall, heart, extra- and periocular mesoderm and right pulmonary isomerismK Kitamura
Mitsubishi Kasei Institute of Life Sciences, Machida, Tokyo 194 8511, Japan
Development 126:5749-58. 1999....
- Three human ARX mutations cause the lissencephaly-like and mental retardation with epilepsy-like pleiotropic phenotypes in miceKunio Kitamura
Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan
Hum Mol Genet 18:3708-24. 2009....
- Mutations of ARX are associated with striking pleiotropy and consistent genotype-phenotype correlationMitsuhiro Kato
Department of Human Genetics, The University of Chicago, Chicago, Illinois 60637, USA
Hum Mutat 23:147-59. 2004....
- Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomouslyTsutomu Hirata
Laboratory for Vertebrate Axis Formation, Center for Developmental Biology, RIKEN, Kobe 650 0047, Japan
Development 133:1433-43. 2006..These findings suggest that signals from olfactory sensory neurons contribute to the proper formation of the olfactory bulb...
- Pitx2 prevents osteoblastic transdifferentiation of myoblasts by bone morphogenetic proteinsMakoto Hayashi
Department of Biochemistry, The Cancer Institute of the Japanese Foundation for Cancer Research, 3 10 6 Ariake, Koto ku, Tokyo 135 8550, Japan
J Biol Chem 283:565-71. 2008..These findings suggest that Pitx2 suppresses osteogenic signals induced by BMPs in myoblasts to prevent their osteoblastic conversion...
- Prognostic significance of T-cell or cytotoxic molecules phenotype in classical Hodgkin's lymphoma: a clinicopathologic studyNaoko Asano
Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan
J Clin Oncol 24:4626-33. 2006..The aim of this study was to clarify the association between phenotypic expression and clinical outcome in CHL...
- Alterations in mRNA expression of myelin proteins in the sciatic nerves and brains of streptozotocin-induced diabetic ratsRei Kawashima
Department of Biochemistry, Kitasato University School of Medicine, 1 15 1 Kitasato, Sagamihara shi, Kanagawa, Japan
Neurochem Res 32:1002-10. 2007..Considering the functional significance of myelin proteins, this impairment of protein expression is possibly involved in the pathogenesis of diabetic neuropathy, including that in brain disorders...
- BMI-1 is highly expressed in M0-subtype acute myeloid leukemiaMasashi Sawa
Department of Molecular Medicine and Hematology, Nagoya University Graduate School of Medicine, Nagoya, Japan
Int J Hematol 82:42-7. 2005..These results indicated that a subgroup of M0 patients has a high expression level of polycomb group gene BMI-1, which may contribute to leukemogenesis...