Atsushi Kubo

Summary

Affiliation: Nara Medical University
Country: Japan

Publications

  1. doi The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm
    Atsushi Kubo
    First Department of Internal Medicine, Nara Medical University, Nara, Japan
    Hepatology 51:633-41. 2010
  2. pmc Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population
    Atsushi Kubo
    First Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan
    PLoS ONE 6:e24058. 2011
  3. pmc Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis
    Kuniko Kimura
    First Department of Internal Medicine, Nara Medical University, 840 Shijo, Kashihara, Nara 634 8522, Japan
    Am J Physiol Renal Physiol 295:F1023-9. 2008
  4. ncbi Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer
    Takeo Nomi
    Department of Surgery, Second Department of Internal Medicine, First Department of Internal Medicine, Nara Medical University, Nara, Japan
    Clin Cancer Res 13:2151-7. 2007
  5. doi Effects of Wnt-10b on proliferation and differentiation of adult murine skin-derived CD34 and CD49f double-positive cells
    Yukiteru Ouji
    Program in Tissue Engineering, Department of Parasitology, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8521, Japan
    J Biosci Bioeng 110:217-22. 2010
  6. ncbi Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8521, Japan
    Oncol Rep 24:501-5. 2010
  7. ncbi In vitro effects of Habu snake venom on cultured mesangial cells
    Atsushi Kubo
    Department of Public Health, Nara Medical University, Kashihara, Nara, Japan
    Nephron 92:665-72. 2002
  8. ncbi Significance and therapeutic potential of prostaglandin E2 receptor in hepatic ischemia/reperfusion injury in mice
    Yukiyasu Kuzumoto
    Department of Surgery, Nara Medical University, Nara, Japan
    Hepatology 42:608-17. 2005
  9. ncbi Treatment with recombinant placental growth factor (PlGF) enhances both angiogenesis and arteriogenesis and improves survival after myocardial infarction
    Yukiji Takeda
    First Department of Internal Medicine, Nara Medical University, Kashihara, Japan
    Circ J 73:1674-82. 2009
  10. doi Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy
    Yukinari Yamaguchi
    First Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan
    Am J Kidney Dis 54:653-64. 2009

Collaborators

Detail Information

Publications10

  1. doi The homeobox gene Hex regulates hepatocyte differentiation from embryonic stem cell-derived endoderm
    Atsushi Kubo
    First Department of Internal Medicine, Nara Medical University, Nara, Japan
    Hepatology 51:633-41. 2010
    ....
  2. pmc Pdx1 and Ngn3 overexpression enhances pancreatic differentiation of mouse ES cell-derived endoderm population
    Atsushi Kubo
    First Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan
    PLoS ONE 6:e24058. 2011
    ....
  3. pmc Stable expression of HIF-1alpha in tubular epithelial cells promotes interstitial fibrosis
    Kuniko Kimura
    First Department of Internal Medicine, Nara Medical University, 840 Shijo, Kashihara, Nara 634 8522, Japan
    Am J Physiol Renal Physiol 295:F1023-9. 2008
    ..In conclusion, HIF-1alpha appears to be a critical contributor to the progression of renal fibrosis and could be a useful target for its treatment...
  4. ncbi Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer
    Takeo Nomi
    Department of Surgery, Second Department of Internal Medicine, First Department of Internal Medicine, Nara Medical University, Nara, Japan
    Clin Cancer Res 13:2151-7. 2007
    ..In this study, we tried to reveal the clinical importance and therapeutic potential of the PD-L/PD-1 pathway in pancreatic cancer, which is one of the most aggressive and intractable malignant tumors...
  5. doi Effects of Wnt-10b on proliferation and differentiation of adult murine skin-derived CD34 and CD49f double-positive cells
    Yukiteru Ouji
    Program in Tissue Engineering, Department of Parasitology, Nara Medical University, 840 Shijo Cho, Kashihara, Nara 634 8521, Japan
    J Biosci Bioeng 110:217-22. 2010
    ..These results suggest that Wnt-10b promotes differentiation of epithelial stem/progenitor cells in the skin...
  6. ncbi Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance
    Kanya Honoki
    Department of Orthopedic Surgery, Nara Medical University, Kashihara, Nara 634 8521, Japan
    Oncol Rep 24:501-5. 2010
    ..Although ALDH1 elevation was not sufficient for representing sarcoma stem cells, the efficient detoxification could contribute to the chemo-resistant properties of the stem-like sphere cells form human sarcoma...
  7. ncbi In vitro effects of Habu snake venom on cultured mesangial cells
    Atsushi Kubo
    Department of Public Health, Nara Medical University, Kashihara, Nara, Japan
    Nephron 92:665-72. 2002
    ..To elucidate the in vitro effects of HSV, we examined whether HSV itself could have direct effects on the cultured mesangial cells, such as cell proliferation and activation of chemokine gene expression...
  8. ncbi Significance and therapeutic potential of prostaglandin E2 receptor in hepatic ischemia/reperfusion injury in mice
    Yukiyasu Kuzumoto
    Department of Surgery, Nara Medical University, Nara, Japan
    Hepatology 42:608-17. 2005
    ..In sharp contrast, 80% of mice treated with the EP4 agonist survived. In conclusion, the PGE2-EP4 signaling pathway has an inhibitory role in hepatic I/R injury. An EP4 agonist effectively protects against ischemic injury...
  9. ncbi Treatment with recombinant placental growth factor (PlGF) enhances both angiogenesis and arteriogenesis and improves survival after myocardial infarction
    Yukiji Takeda
    First Department of Internal Medicine, Nara Medical University, Kashihara, Japan
    Circ J 73:1674-82. 2009
    ..However, the effects of exogenous PlGF administration on the healing process after MI are not fully understood. The purpose of the present study was to examine whether PlGF treatment has therapeutic potential in MI...
  10. doi Epithelial-mesenchymal transition as a potential explanation for podocyte depletion in diabetic nephropathy
    Yukinari Yamaguchi
    First Department of Internal Medicine, Nara Medical University, Kashihara, Nara, Japan
    Am J Kidney Dis 54:653-64. 2009
    ....