Kenta Sumiyama

Summary

Affiliation: National Institute of Genetics
Country: Japan

Publications

  1. pmc Theria-specific homeodomain and cis-regulatory element evolution of the Dlx3-4 bigene cluster in 12 different mammalian species
    Kenta Sumiyama
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    J Exp Zool B Mol Dev Evol 318:639-50. 2012
  2. doi request reprint A simple and highly efficient transgenesis method in mice with the Tol2 transposon system and cytoplasmic microinjection
    Kenta Sumiyama
    Division of Population Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan
    Genomics 95:306-11. 2010
  3. doi request reprint Loss-of-function mutation in a repressor module of human-specifically activated enhancer HACNS1
    Kenta Sumiyama
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    Mol Biol Evol 28:3005-7. 2011
  4. doi request reprint A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings
    Tomoko Sagai
    Mammalian Genetics Laboratory, National Institute of Genetics, Shizuoka ken 411 8540, Japan
    Development 136:1665-74. 2009
  5. doi request reprint Evolution of conserved non-coding sequences within the vertebrate Hox clusters through the two-round whole genome duplications revealed by phylogenetic footprinting analysis
    Masatoshi Matsunami
    Department of Genetics, School of Life Science, The Graduate University for Advanced Studies Sokendai, Mishima, 411 8540, Japan
    J Mol Evol 71:427-36. 2010
  6. pmc Transposon-mediated BAC transgenesis in zebrafish and mice
    Maximiliano L Suster
    Division of Molecular and Developmental Biology, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    BMC Genomics 10:477. 2009
  7. pmc A new database (GCD) on genome composition for eukaryote and prokaryote genome sequences and their initial analyses
    Kirill Kryukov
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    Genome Biol Evol 4:501-12. 2012
  8. ncbi request reprint Adaptive evolution of the IgA hinge region in primates
    Kenta Sumiyama
    Department of Biological Sciences, Graduate School of Science, University of Tokyo Laboratory of Evolutionary Genetics, National Institute of Genetics, Mishima 411 8540, Japan
    Mol Biol Evol 19:1093-9. 2002
  9. ncbi request reprint Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner
    Masaru Tamura
    Mammalian Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 0845, Japan
    Genomics 89:618-29. 2007

Collaborators

Detail Information

Publications9

  1. pmc Theria-specific homeodomain and cis-regulatory element evolution of the Dlx3-4 bigene cluster in 12 different mammalian species
    Kenta Sumiyama
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    J Exp Zool B Mol Dev Evol 318:639-50. 2012
    ..These observations, taken together with our molecular evolutionary data, suggest that theria-specific episodic changes in the I37-2 element may have contributed to craniofacial innovation at the base of the mammalian lineage...
  2. doi request reprint A simple and highly efficient transgenesis method in mice with the Tol2 transposon system and cytoplasmic microinjection
    Kenta Sumiyama
    Division of Population Genetics, National Institute of Genetics, Mishima, Shizuoka, Japan
    Genomics 95:306-11. 2010
    ..Considering its simplicity and perfect compatibility with existing pronuclear microinjection facilities, we propose that the Tol2:CI method is applicable to high throughput functional genomics studies...
  3. doi request reprint Loss-of-function mutation in a repressor module of human-specifically activated enhancer HACNS1
    Kenta Sumiyama
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    Mol Biol Evol 28:3005-7. 2011
    ..This result infers that loss of function in the HACNS1 81-bp region, possibly via a BGC, played an important role in human-specific evolution...
  4. doi request reprint A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings
    Tomoko Sagai
    Mammalian Genetics Laboratory, National Institute of Genetics, Shizuoka ken 411 8540, Japan
    Development 136:1665-74. 2009
    ..Thus, this long-range enhancer is indispensable for morphogenesis of the pharyngeal apparatus...
  5. doi request reprint Evolution of conserved non-coding sequences within the vertebrate Hox clusters through the two-round whole genome duplications revealed by phylogenetic footprinting analysis
    Masatoshi Matsunami
    Department of Genetics, School of Life Science, The Graduate University for Advanced Studies Sokendai, Mishima, 411 8540, Japan
    J Mol Evol 71:427-36. 2010
    ..The authors also compared vertebrate CNSs with amphioxus CNSs within the Hox cluster, and found that two CNSs in the HoxA and HoxB clusters retain homology with amphioxus CNSs through the two-round whole genome duplications...
  6. pmc Transposon-mediated BAC transgenesis in zebrafish and mice
    Maximiliano L Suster
    Division of Molecular and Developmental Biology, National Institute of Genetics, Mishima, Shizuoka 411 8540, Japan
    BMC Genomics 10:477. 2009
    ..Although conventional methods for BAC transgenesis have been very fruitful, complementary methods for generating single copy BAC integrations would be desirable for many applications...
  7. pmc A new database (GCD) on genome composition for eukaryote and prokaryote genome sequences and their initial analyses
    Kirill Kryukov
    Division of Population Genetics, National Institute of Genetics, Mishima, Japan
    Genome Biol Evol 4:501-12. 2012
    ..Mammalian genomes showed the largest deviation among animals. The results of comparison are available online at http://esper.lab.nig.ac.jp/genome-composition-database/...
  8. ncbi request reprint Adaptive evolution of the IgA hinge region in primates
    Kenta Sumiyama
    Department of Biological Sciences, Graduate School of Science, University of Tokyo Laboratory of Evolutionary Genetics, National Institute of Genetics, Mishima 411 8540, Japan
    Mol Biol Evol 19:1093-9. 2002
    ....
  9. ncbi request reprint Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner
    Masaru Tamura
    Mammalian Genetics Laboratory, Genetic Strains Research Center, National Institute of Genetics, 1111 Yata, Mishima, Shizuoka 411 0845, Japan
    Genomics 89:618-29. 2007
    ..Further database searching revealed the presence of other related genes with a similar N-terminal motif. These results suggest that the Gsdm family and related genes have evolved divergent epithelial expression profiles...