Ryo Kimura

Summary

Affiliation: Osaka University
Country: Japan

Publications

  1. doi request reprint Posterior reversible encephalopathy syndrome in chronic alcoholism with acute psychiatric symptoms
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka 558 8558, Japan
    Gen Hosp Psychiatry 32:447.e3-5. 2010
  2. doi request reprint Treatment of delirium with ramelteon: initial experience in three patients
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka, 558 8558, Japan
    Gen Hosp Psychiatry 33:407-9. 2011
  3. doi request reprint SORL1 is genetically associated with Alzheimer disease in a Japanese population
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka, Japan
    Neurosci Lett 461:177-80. 2009
  4. doi request reprint Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, 3 1 56 Bandai Higashi, Sumiyoshi ku, Osaka 558 8558, Japan
    Neurosci Lett 487:354-7. 2011
  5. doi request reprint Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon4 carriers
    Nuripa Jenishbekovna Aidaralieva
    Department of Psychiatry, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    J Hum Genet 53:296-302. 2008
  6. doi request reprint Decrease of dynamin 2 levels in late-onset Alzheimer's disease alters Abeta metabolism
    Eiichiro Kamagata
    Department of Geriatric Medicine, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Biochem Biophys Res Commun 379:691-5. 2009
  7. ncbi request reprint The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease
    Ryo Kimura
    Department of Psychiatry, Osaka University Graduate School of Medicine, 2 2 D3 Yamadaoka, Suita, Osaka 565 0871, Japan
    Hum Mol Genet 16:15-23. 2007
  8. pmc Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier
    Takashi Morihara
    Department of Psychiatry, Graduate School of Medicine, Osaka University, Osaka 565 0871, Japan
    Proc Natl Acad Sci U S A 111:2638-43. 2014
  9. doi request reprint The effects of memantine on a patient having preclinical dementia with Lewy bodies
    Masahiko Takaya
    Department of Psychiatry, Osaka General Medical Center, Osaka 558 8558, Japan
    Gen Hosp Psychiatry 35:327.e1-327.e3. 2013
  10. doi request reprint KIBRA genetic polymorphism influences episodic memory in Alzheimer's disease, but does not show association with disease in a Japanese cohort
    Noriyuki Hayashi
    Department of Psychiatry, Osaka University Graduate School of Medicine, Japan
    Dement Geriatr Cogn Disord 30:302-8. 2010

Collaborators

Detail Information

Publications13

  1. doi request reprint Posterior reversible encephalopathy syndrome in chronic alcoholism with acute psychiatric symptoms
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka 558 8558, Japan
    Gen Hosp Psychiatry 32:447.e3-5. 2010
    ..To highlight the association between posterior reversible encephalopathy syndrome (PRES) and chronic alcoholism...
  2. doi request reprint Treatment of delirium with ramelteon: initial experience in three patients
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka, 558 8558, Japan
    Gen Hosp Psychiatry 33:407-9. 2011
    ..The aim of the present study was to determine the efficacy of ramelteon for treating delirium...
  3. doi request reprint SORL1 is genetically associated with Alzheimer disease in a Japanese population
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka, Japan
    Neurosci Lett 461:177-80. 2009
    ..This risk was evident in non-carriers of the apolipoprotein E-epsilon 4 allele, but not in its carriers. Our results support the evidence that genetic variants of SORL1 affect susceptibility to late-onset AD...
  4. doi request reprint Association between CAG repeat length in the PPP2R2B gene and Alzheimer disease in the Japanese population
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, 3 1 56 Bandai Higashi, Sumiyoshi ku, Osaka 558 8558, Japan
    Neurosci Lett 487:354-7. 2011
    ..The results suggest that CAG repeat lengths in the PPP2R2B gene may be potential genetic markers for AD susceptibility in the Japanese population...
  5. doi request reprint Dynamin 2 gene is a novel susceptibility gene for late-onset Alzheimer disease in non-APOE-epsilon4 carriers
    Nuripa Jenishbekovna Aidaralieva
    Department of Psychiatry, Osaka University Graduate School of Medicine, Suita, Osaka 565 0871, Japan
    J Hum Genet 53:296-302. 2008
    ..We propose that the DNM2 gene is a novel susceptibility gene for LOAD...
  6. doi request reprint Decrease of dynamin 2 levels in late-onset Alzheimer's disease alters Abeta metabolism
    Eiichiro Kamagata
    Department of Geriatric Medicine, Osaka University Graduate School of Medicine, 2 2 Yamadaoka, Suita, Osaka, Japan
    Biochem Biophys Res Commun 379:691-5. 2009
    ..These data suggest that DNM2 expression is reduced in LOAD, which results in the accumulation of APP in lipid raft-rich plasma membranes. Consequently, Abeta secretion may increase in LOAD neurons...
  7. ncbi request reprint The DYRK1A gene, encoded in chromosome 21 Down syndrome critical region, bridges between beta-amyloid production and tau phosphorylation in Alzheimer disease
    Ryo Kimura
    Department of Psychiatry, Osaka University Graduate School of Medicine, 2 2 D3 Yamadaoka, Suita, Osaka 565 0871, Japan
    Hum Mol Genet 16:15-23. 2007
    ..Our result indicates that DYRK1A could be a key molecule bridging between beta-amyloid production and tau phosphorylation in AD...
  8. pmc Transcriptome analysis of distinct mouse strains reveals kinesin light chain-1 splicing as an amyloid-β accumulation modifier
    Takashi Morihara
    Department of Psychiatry, Graduate School of Medicine, Osaka University, Osaka 565 0871, Japan
    Proc Natl Acad Sci U S A 111:2638-43. 2014
    ..This unique combination of distinct mouse strains and model mice with transcriptomics is expected to be useful for the study of genetic mechanisms of other complex diseases. ..
  9. doi request reprint The effects of memantine on a patient having preclinical dementia with Lewy bodies
    Masahiko Takaya
    Department of Psychiatry, Osaka General Medical Center, Osaka 558 8558, Japan
    Gen Hosp Psychiatry 35:327.e1-327.e3. 2013
    ..We hypothesized that memantine would have similar effects on a patient having Charles Bonnet syndrome, preclinical DLB...
  10. doi request reprint KIBRA genetic polymorphism influences episodic memory in Alzheimer's disease, but does not show association with disease in a Japanese cohort
    Noriyuki Hayashi
    Department of Psychiatry, Osaka University Graduate School of Medicine, Japan
    Dement Geriatr Cogn Disord 30:302-8. 2010
    ..Importantly, the association between KIBRA and episodic memory in AD has never been addressed. In this study, we investigated whether the KIBRA rs17070145 SNP influences AD episodic memory and the disease in a Japanese cohort...
  11. ncbi request reprint Secretion of the Notch-1 Abeta-like peptide during Notch signaling
    Masayasu Okochi
    Department of Post Genomics and Diseases, Division of Psychiatry and Behavioral Proteomics, Osaka University Graduate School of Medicine, Osaka 565 0871, Japan
    J Biol Chem 281:7890-8. 2006
    ..We anticipate that this study will open the door to searches for markers of RIP signaling and surrogate markers for Abeta42 production...
  12. doi request reprint Comparison of the clinical features of suicide attempters by jumping from a height and those by self-stabbing in Japan
    Ryo Kimura
    Department of Psychiatry, Osaka General Medical Center, Osaka, Japan
    J Affect Disord 150:695-8. 2013
    ..The present study compared the clinical features of psychiatric patients in Japan who attempted suicide by jumping from a height and those who attempted suicide by self-stabbing...
  13. ncbi request reprint Altered localization of amyloid precursor protein under endoplasmic reticulum stress
    Takashi Kudo
    Division of Psychiatry, Course of Internal Medicine, Osaka University Graduate School of Medicine, Osaka, Japan
    Biochem Biophys Res Commun 344:525-30. 2006
    ..These findings suggest that induction of BiP/GRP78 during ER stress may be one of the regulatory mechanisms of Abeta generation...