Affiliation: Teijin Institute for Bio-Medical Research
- Bronchiolar chemokine expression is different after single versus repeated cigarette smoke exposureTomoko Betsuyaku
First Department of Medicine, Hokkaido University School of Medicine, Kita 15, Nishi 7, Kita ku, Sapporo, 060 8683, Japan
Respir Res 9:7. 2008..Bronchioles are critical zones in cigarette smoke (CS)-induced lung inflammation. However, there have been few studies on the in vivo dynamics of cytokine gene expression in bronchiolar epithelial cells in response to CS...
- Pharmacological activities of TEI-8362, a novel inhibitor of human neutrophil elastaseH Mitsuhashi
Teijin Institute for Bio Medical Research, Hino, Tokyo, Japan
Br J Pharmacol 126:1147-52. 1999..t., i.v., or inhalant administration of TEI-8362. 5. These pharmacological actions of TEI-8362 suggest that this drug has therapeutic value in the treatment of destructive lung diseases due to neutrophils...
- Appearance of cytokine-induced neutrophil chemoattractant isoforms and immunolocalization of them in lipopolysaccharide-induced acute lung inflammation in ratsH Mitsuhashi
Teijin Institute for Biomedical Research, Hino, Tokyo, Japan
Inflamm Res 48:588-93. 1999..To determine the major component and the source of CINC in airways, we investigated the change in appearance of CINC isoforms after exposure of rats to lipopolysaccharide...