Y Wakutani

Summary

Affiliation: Tottori University
Country: Japan

Publications

  1. ncbi request reprint The regulatory region polymorphisms of the MTHFR gene are not associated with Alzheimer's disease
    Yosuke Wakutani
    Department of Neurology, Institute of Neurological Sciences, Tottori University, Yonago, Japan
    Dement Geriatr Cogn Disord 17:147-50. 2004
  2. ncbi request reprint Gene symbol: APP. Disease: Familial Alzheimer's disease
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36 1 Nishimachi, Yonago shi 683 8504, Japan
    Hum Genet 117:299. 2005
  3. ncbi request reprint Mutational analysis of carbamoylphosphate synthetase I deficiency in three Japanese patients
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Tottori University, Yonago 683 8504, Japan
    J Inherit Metab Dis 27:787-8. 2004
  4. ncbi request reprint Genetic analysis of vascular factors in Alzheimer's disease
    Yosuke Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36 1 Nishimachi, Yonago 683 8504, Japan
    Ann N Y Acad Sci 977:232-8. 2002
  5. ncbi request reprint [Causative genes in Alzheimer's disease]
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori Universiey
    Nippon Ronen Igakkai Zasshi 38:117-20. 2001
  6. pmc Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer's disease
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    J Neurol Neurosurg Psychiatry 75:1039-42. 2004
  7. ncbi request reprint Lipoprotein(a) phenotypes in patients with vascular dementia
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    Dement Geriatr Cogn Disord 11:135-8. 2000
  8. ncbi request reprint [Analysis of causative genes and genetic risk factor in Alzheimer's disease]
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University
    Nihon Ronen Igakkai Zasshi 38:769-71. 2001
  9. ncbi request reprint [A case of late-onset carbamoyl phosphate synthetase I deficiency, presenting periodic psychotic episodes coinciding with menstrual periods]
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University
    Rinsho Shinkeigaku 41:780-5. 2001
  10. ncbi request reprint Elevated interleukin-6 levels in cerebrospinal fluid of vascular dementia patients
    K Wada-Isoe
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    Acta Neurol Scand 110:124-7. 2004

Detail Information

Publications12

  1. ncbi request reprint The regulatory region polymorphisms of the MTHFR gene are not associated with Alzheimer's disease
    Yosuke Wakutani
    Department of Neurology, Institute of Neurological Sciences, Tottori University, Yonago, Japan
    Dement Geriatr Cogn Disord 17:147-50. 2004
    ..Thus, our study does not reinforce the hypothesis of an independent involvement of the MTHFR gene upstream region polymorphisms in AD risk...
  2. ncbi request reprint Gene symbol: APP. Disease: Familial Alzheimer's disease
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36 1 Nishimachi, Yonago shi 683 8504, Japan
    Hum Genet 117:299. 2005
  3. ncbi request reprint Mutational analysis of carbamoylphosphate synthetase I deficiency in three Japanese patients
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Tottori University, Yonago 683 8504, Japan
    J Inherit Metab Dis 27:787-8. 2004
    ....
  4. ncbi request reprint Genetic analysis of vascular factors in Alzheimer's disease
    Yosuke Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, 36 1 Nishimachi, Yonago 683 8504, Japan
    Ann N Y Acad Sci 977:232-8. 2002
    ..In our study, we found a significant ethnic difference of the genotype distribution, but failed to replicate the positive association between the I allele and AD...
  5. ncbi request reprint [Causative genes in Alzheimer's disease]
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori Universiey
    Nippon Ronen Igakkai Zasshi 38:117-20. 2001
    ..05, p < 0.05, respectively). High levels of apoE mRNA in AD and DS may play an important role in the development of Alzheimer pathology...
  6. pmc Novel amyloid precursor protein gene missense mutation (D678N) in probable familial Alzheimer's disease
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    J Neurol Neurosurg Psychiatry 75:1039-42. 2004
    ..To describe a novel missense mutation, Asp678Asn (D678N), in the amyloid precursor protein (APP) gene in a Japanese pedigree of probable familial Alzheimer's disease (FAD)...
  7. ncbi request reprint Lipoprotein(a) phenotypes in patients with vascular dementia
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    Dement Geriatr Cogn Disord 11:135-8. 2000
    ..Abnormally high serum levels of Lp(a) in patients with CVD and VD seemed to be due to specific increases in low-molecular-weight apolipoprotein(a) isoforms in Lp(a)...
  8. ncbi request reprint [Analysis of causative genes and genetic risk factor in Alzheimer's disease]
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University
    Nihon Ronen Igakkai Zasshi 38:769-71. 2001
    ..The frequencies of P and X alleles in SAD were significantly higher than those in the control group (p < 0.05). Polymorphism of the ER alpha gene may be a genetic risk factor for SAD...
  9. ncbi request reprint [A case of late-onset carbamoyl phosphate synthetase I deficiency, presenting periodic psychotic episodes coinciding with menstrual periods]
    Y Wakutani
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University
    Rinsho Shinkeigaku 41:780-5. 2001
    ..Genomic DNA analysis showed that she was heterozygous in V1149G mutation. The mutation allele was derived from her father. The causative factor for absence or very low level of maternal CPSI mRNA will require further analysis...
  10. ncbi request reprint Elevated interleukin-6 levels in cerebrospinal fluid of vascular dementia patients
    K Wada-Isoe
    Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Yonago, Japan
    Acta Neurol Scand 110:124-7. 2004
    ..To investigate a possible implication of inflammatory processes in the development of dementia in cerebrovascular disease...
  11. ncbi request reprint Diagnostic significance of tau protein in cerebrospinal fluid from patients with corticobasal degeneration or progressive supranuclear palsy
    K Urakami
    Division of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Nishimachi 36 1, 683 8504, Yonago, Japan
    J Neurol Sci 183:95-8. 2001
    ....
  12. ncbi request reprint Heterogeneity within a large kindred with frontotemporal dementia: a novel progranulin mutation
    A C Bruni
    Regional Neurogenetic Centre, Lamezia Terme, CZ, Italy
    Neurology 69:140-7. 2007
    ..Frontotemporal dementia (FTD) in several 17q21-linked families was recently explained by truncating mutations in the progranulin gene (GRN)...