Yasunori Sasakura

Summary

Affiliation: University of Tsukuba
Country: Japan

Publications

  1. ncbi request reprint Postplasmic/PEM RNAs: a class of localized maternal mRNAs with multiple roles in cell polarity and development in ascidian embryos
    Francois Prodon
    Department of Biology, Graduate School of Science, Osaka University, Osaka, Japan
    Dev Dyn 236:1698-715. 2007
  2. pmc Monoaminergic modulation of photoreception in ascidian: evidence for a proto-hypothalamo-retinal territory
    Florian Razy-Krajka
    Neurobiology and Development, UPR, Institut de Neurobiologie Alfred Fessard, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    BMC Biol 10:45. 2012
  3. doi request reprint Retinoic acid-driven Hox1 is required in the epidermis for forming the otic/atrial placodes during ascidian metamorphosis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Development 139:2156-60. 2012
  4. doi request reprint Ascidians as excellent chordate models for studying the development of the nervous system during embryogenesis and metamorphosis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Dev Growth Differ 54:420-37. 2012
  5. pmc Transposon-mediated insertional mutagenesis revealed the functions of animal cellulose synthase in the ascidian Ciona intestinalis
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Proc Natl Acad Sci U S A 102:15134-9. 2005
  6. doi request reprint Maternal factor-mediated epigenetic gene silencing in the ascidian Ciona intestinalis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Mol Genet Genomics 283:99-110. 2010
  7. doi request reprint Excision and transposition activity of Tc1/mariner superfamily transposons in sea urchin embryos
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Zoolog Sci 27:256-62. 2010
  8. pmc Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Genome Biol 8:S3. 2007
  9. ncbi request reprint Enhancer detection in the ascidian Ciona intestinalis with transposase-expressing lines of Minos
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 237:39-50. 2008
  10. ncbi request reprint Germline transgenesis and insertional mutagenesis in the ascidian Ciona intestinalis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 236:1758-67. 2007

Detail Information

Publications56

  1. ncbi request reprint Postplasmic/PEM RNAs: a class of localized maternal mRNAs with multiple roles in cell polarity and development in ascidian embryos
    Francois Prodon
    Department of Biology, Graduate School of Science, Osaka University, Osaka, Japan
    Dev Dyn 236:1698-715. 2007
    ..Finally, we propose a speculative model integrating recent data, and we also discuss the relationship between postplasmic/PEM RNAs, posterior specification, and germ cell formation in ascidians...
  2. pmc Monoaminergic modulation of photoreception in ascidian: evidence for a proto-hypothalamo-retinal territory
    Florian Razy-Krajka
    Neurobiology and Development, UPR, Institut de Neurobiologie Alfred Fessard, Centre National de la Recherche Scientifique, Gif sur Yvette, France
    BMC Biol 10:45. 2012
    ..Except for photoreceptors, the existence of homologs of retinal cells remains uncertain outside vertebrates...
  3. doi request reprint Retinoic acid-driven Hox1 is required in the epidermis for forming the otic/atrial placodes during ascidian metamorphosis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Development 139:2156-60. 2012
    ..Our results suggest that RA-Hox1 in the epidermal ectoderm played a key role in the acquisition of the otic placode during chordate evolution...
  4. doi request reprint Ascidians as excellent chordate models for studying the development of the nervous system during embryogenesis and metamorphosis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Dev Growth Differ 54:420-37. 2012
    ..The larval glial cells in the CNS are the major source for the formation of the adult CNS, and some of the glial cells produce adult neurons...
  5. pmc Transposon-mediated insertional mutagenesis revealed the functions of animal cellulose synthase in the ascidian Ciona intestinalis
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Proc Natl Acad Sci U S A 102:15134-9. 2005
    ..It is likely that ascidian cellulose synthase is required for the coordination of the metamorphic events in the trunk and tail in addition to cellulose biosynthesis...
  6. doi request reprint Maternal factor-mediated epigenetic gene silencing in the ascidian Ciona intestinalis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Mol Genet Genomics 283:99-110. 2010
    ..The silencing starts during oogenesis and continues after fertilization without any tissue specificity. We found that post-transcriptional degradation of the gfp mRNA is involved in MGS...
  7. doi request reprint Excision and transposition activity of Tc1/mariner superfamily transposons in sea urchin embryos
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Zoolog Sci 27:256-62. 2010
    ..This study suggests that Minos is active in a broad range of non-host organisms and can be used as a transformation tool in sea urchin embryos...
  8. pmc Transposon mediated transgenesis in a marine invertebrate chordate: Ciona intestinalis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Genome Biol 8:S3. 2007
    ..A Tc1/mariner superfamily transposon, Minos, has excision and transposition activities in Ciona. Minos enables the creation of stable transgenic lines, enhancer detection, and insertional mutagenesis...
  9. ncbi request reprint Enhancer detection in the ascidian Ciona intestinalis with transposase-expressing lines of Minos
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 237:39-50. 2008
    ..This technique allowed us to isolate transgenic lines that express GFP in restricted tissues. This system provides an easy and efficient method for large-scale enhancer detection in Ciona intestinalis...
  10. ncbi request reprint Germline transgenesis and insertional mutagenesis in the ascidian Ciona intestinalis
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 236:1758-67. 2007
    ..This review specifically addresses recent achievements of transformation techniques in Ciona, as exemplified using the Minos system...
  11. doi request reprint Efficient transposition of a single Minos transposon copy in the genome of the ascidian Ciona intestinalis with a transgenic line expressing transposase in eggs
    Akiko Hozumi
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Dev Dyn 239:1076-88. 2010
    ..This characteristic of Minos is in contrast to that of the Sleeping Beauty transposon, which causes frequent intrachromosomal transposition...
  12. pmc Germ-line transgenesis of the Tc1/mariner superfamily transposon Minos in Ciona intestinalis
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Proc Natl Acad Sci U S A 100:7726-30. 2003
    ..In addition, an enhancer-trap line was obtained. This is a demonstration of efficient, Minos-mediated transgenesis in marine invertebrates...
  13. doi request reprint Germline transgenesis of the chordate Ciona intestinalis with hyperactive variants of sleeping beauty transposable element
    Akiko Hozumi
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 242:30-43. 2013
    ..Adding another transposon system in this organism enables us to conduct genetic techniques which can only be realized with the use of two transposons...
  14. ncbi request reprint High-throughput enhancer trap by remobilization of transposon Minos in Ciona intestinalis
    Satoko Awazu
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Genesis 45:307-17. 2007
    ..This high-throughput enhancer trap screen will be useful to create new marker transgenic lines showing reporter gene expression in specific tissues and to identify novel patterns of gene expression...
  15. doi request reprint Enhancer activity sensitive to the orientation of the gene it regulates in the chordate genome
    Akiko Hozumi
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Dev Biol 375:79-91. 2013
    ..The different sensitivity of the enhancers to the orientation of the transgene is a cause of CNS-specific GFP expression in the E15 line...
  16. ncbi request reprint Germline transgenesis of the ascidian Ciona intestinalis by electroporation
    Terumi Matsuoka
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, Japan
    Genesis 41:67-72. 2005
    ....
  17. ncbi request reprint An enhancer trap in the ascidian Ciona intestinalis identifies enhancers of its Musashi orthologous gene
    Satoko Awazu
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Biol 275:459-72. 2004
    ..These results clearly demonstrate that an enhancer trap event that entrapped enhancers of Ci-Musashi occurred in C. intestinalis...
  18. ncbi request reprint A genomewide survey of developmentally relevant genes in Ciona intestinalis. VII. Molecules involved in the regulation of cell polarity and actin dynamics
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Genes Evol 213:273-83. 2003
    ..Ciona intestinalis, therefore, may provide refined clues for the study of vertebrate development and evolution...
  19. doi request reprint Delineating metamorphic pathways in the ascidian Ciona intestinalis
    Akie Nakayama-Ishimura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, Japan
    Dev Biol 326:357-67. 2009
    ..Proc. Natl. Acad. Sci. U. S. A. 102, 15134-15139.), which also show abnormal metamorphosis. These findings suggest a model by which ascidian metamorphic events can be classified into four groups initiated by different pathways...
  20. ncbi request reprint A genomewide survey of developmentally relevant genes in Ciona intestinalis. X. Genes for cell junctions and extracellular matrix
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Genes Evol 213:303-13. 2003
    ..In vertebrates these ancestral cell junctions appear to have evolved into more diverse, and possibly more complex, forms, compared with those in their urochordate siblings...
  21. ncbi request reprint Application of Minos, one of the Tc1/mariner superfamily transposable elements, to ascidian embryos as a tool for insertional mutagenesis
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Gene 308:11-20. 2003
    ..From these tests, we concluded that Minos transposase has complete activity when it is expressed in C. intestinalis, suggesting that Minos has the potential to be used for genome-wide insertional mutagenesis of C. intestinalis...
  22. doi request reprint Developmental Control of Cell-Cycle Compensation Provides a Switch for Patterned Mitosis at the Onset of Chordate Neurulation
    Yosuke Ogura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan Electronic address
    Dev Cell 37:148-61. 2016
    ..We propose that such developmentally regulated cell-cycle compensation provides an abrupt switch to spatially patterned mitosis in order to achieve the coordination between mitotic timing and morphogenesis...
  23. ncbi request reprint Ascidians as excellent models for studying cellular events in the chordate body plan
    Yosuke Ogura
    Shimoda Marine Research Center, University of Tsukuba, Shizuoka, Japan
    Biol Bull 224:227-36. 2013
    ..This morphogenetic movement is allowed by an elongation of interphase in the epidermal cell cycles...
  24. doi request reprint Ependymal cells of chordate larvae are stem-like cells that form the adult nervous system
    Takeo Horie
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Nature 469:525-8. 2011
    ..Consequently, the plasticity of non-neuronal ependymal cells and neuronal cells in chordates should be re-examined by future studies...
  25. pmc Improved genome assembly and evidence-based global gene model set for the chordate Ciona intestinalis: new insight into intron and operon populations
    Yutaka Satou
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo, Kyoto, Japan
    Genome Biol 9:R152. 2008
    ....
  26. pmc Transcriptional regulation of a horizontally transferred gene from bacterium to chordate
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Proc Biol Sci 283:. 2016
    ..Therefore, the actinobacterial cellulose synthase could have been potentiated to evolve its new function in the ancestor of tunicates with a higher probability than the evolution depending solely on a spontaneous event...
  27. doi request reprint Hox10-regulated endodermal cell migration is essential for development of the ascidian intestine
    Narudo Kawai
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan Electronic address
    Dev Biol 403:43-56. 2015
    ..Inhibition of this regulation prevented cellular migration. These results suggest that Ci-Hox10 regulates endodermal strand cell migration by forming a protrusion and by reconstructing the extracellular matrix. ..
  28. doi request reprint Nonreproductive role of gonadotropin-releasing hormone in the control of ascidian metamorphosis
    Chisato Kamiya
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 243:1524-35. 2014
    ..In the ascidian Ciona intestinalis, GnRHs and their receptors are expressed in the nervous systems at the larval stage, when animals are not yet capable of reproduction, suggesting that the hormones have non-reproductive roles...
  29. doi request reprint Sustained heterozygosity across a self-incompatibility locus in an inbred ascidian
    Yutaka Satou
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo, Kyoto, Japan
    Mol Biol Evol 32:81-90. 2015
    ..4-Mb heterozygous region. High structural variations might suppress recombination, and this long heterozygous region might represent a preliminary stage of structural differentiation of chromosomes. ..
  30. doi request reprint Tissue-specific and ubiquitous gene knockouts by TALEN electroporation provide new approaches to investigating gene function in Ciona
    Nicholas Treen
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Development 141:481-7. 2014
    ..We also use tissue-specific knockouts to reveal a new function of Fgf3 during ascidian larval metamorphosis. ..
  31. ncbi request reprint Tissue-specific profile of DNA replication in the swimming larvae of Ciona intestinalis
    Akie Nakayama
    Department of Zoology, Graduate School of Science, Kyoto University, Japan
    Zoolog Sci 22:301-9. 2005
    ..Our data showed that DNA synthesis in the larval trunk is not directly associated with the organization of adult organs, but it contributes to the speed of metamorphosis after settlement...
  32. doi request reprint Distribution and structural diversity of cilia in tadpole larvae of the ascidian Ciona intestinalis
    Alu Konno
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Dev Biol 337:42-62. 2010
    ..Extensive description of cilia in the present study gives important insights into the evolution of the ciliary structure and provides a basis for analysis of ciliary functions in establishment of chordate body plan...
  33. doi request reprint Regulatory genes in the ancestral chordate genomes
    Yutaka Satou
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo, Kyoto 606 8501, Japan
    Dev Genes Evol 218:715-21. 2008
    ..The inferred regulatory gene sets of the ancestral chordate would be an important foundation for understanding how tadpole-type larvae, a unique characteristic of chordates, evolved...
  34. doi request reprint Transposon-mediated enhancer detection reveals the location, morphology and development of the cupular organs, which are putative hydrodynamic sensors, in the ascidian Ciona intestinalis
    Naoyuki Ohta
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Zoolog Sci 27:842-50. 2010
    ..To our knowledge, the present study is the first precise description of the ascidian cupular organ, providing evidence that may help to resolve discrepancies among previous studies on the organ...
  35. doi request reprint Germ cell mutations of the ascidian Ciona intestinalis with TALE nucleases
    Keita Yoshida
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Genesis 52:431-9. 2014
    ..TALEN-mediated mutations in the germ cell genome were inherited by the next generation. We conclude that knockout lines of Ciona that have disrupted target genes can be established through TALEN-mediated germ cell mutagenesis...
  36. doi request reprint Efficient targeted mutagenesis of the chordate Ciona intestinalis genome with zinc-finger nucleases
    Narudo Kawai
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Dev Growth Differ 54:535-45. 2012
    ..This suggests that target mutagenesis with ZFNs will be a powerful technique in C. intestinalis...
  37. ncbi request reprint Ciona intestinalis and Oxycomanthus japonicus, representatives of marine invertebrates
    Yasunori Sasakura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Exp Anim 58:459-69. 2009
    ..In consideration of these features, the National BioResource Project (NBRP) has started to support the supply of wild-types, transgenic lines and inbred lines of Ciona intestinalis and Oxycomanthus japonicus...
  38. ncbi request reprint A genomewide survey of developmentally relevant genes in Ciona intestinalis. V. Genes for receptor tyrosine kinase pathway and Notch signaling pathway
    Yutaka Satou
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Genes Evol 213:254-63. 2003
    ..The gene set identified in the present analysis provides an insight into genes for the RTK, MAPK and Notch signaling pathways in the ancient chordate genome and thereby how chordates evolved these signaling pathway...
  39. ncbi request reprint Minos transposon causes germline transgenesis of the ascidian Ciona savignyi
    Terumi Matsuoka
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Growth Differ 46:249-55. 2004
    ..In addition, one insertion seemed to have caused an enhancer trapping. These results indicate that Minos provides a potential tool for transgenic techniques such as insertional mutagenesis in Ciona savignyi...
  40. doi request reprint Coordination of mitosis and morphogenesis: role of a prolonged G2 phase during chordate neurulation
    Yosuke Ogura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Development 138:577-87. 2011
    ..Delaying the precocious cell division by prolonging the S phase with aphidicolin ameliorated the effects of CDC25. These results suggest that the long interphase during the eleventh epidermal cell cycle is required for neurulation...
  41. doi request reprint Large-scale infection of the ascidian Ciona intestinalis by the gregarine Lankesteria ascidiae in an inland culture system
    Kaoru Mita
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Dis Aquat Organ 101:185-95. 2012
    ..The digestive tubes of the diseased animals are occupied by the gregarine apicomplexan parasite Lankesteria ascidiae, suggesting that large-scale infection by this parasite is the cause of long feces syndrome...
  42. doi request reprint Establishment of enhancer detection lines expressing GFP in the gut of the ascidian Ciona intestinalis
    Reiko Yoshida
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Zoolog Sci 29:11-20. 2012
    ..The present data provide the basic information and useful resources for studying gut formation in Ciona...
  43. doi request reprint Simple motor system of the ascidian larva: neuronal complex comprising putative cholinergic and GABAergic/glycinergic neurons
    Takeo Horie
    Department of Life Science, Graduate School of Life Science, University of Hyogo, 3 2 1 Kouto, Kamigori, Ako gun, Hyogo 678 1297, Japan
    Zoolog Sci 27:181-90. 2010
    ..The simple CPG of the ascidian larva may represent the ancestral state of the vertebrate motor system...
  44. pmc CRISPR/Cas9-mediated gene knockout in the ascidian Ciona intestinalis
    Haruka Sasaki
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, 415 0025, Japan
    Dev Growth Differ 56:499-510. 2014
    ..CRISPR/Cas9-mediated mutagenesis will be a powerful method to study gene functions in Ciona along with another genome editing approach using TALE nucleases. ..
  45. pmc Transposon-mediated targeted and specific knockdown of maternally expressed transcripts in the ascidian Ciona intestinalis
    Takako Iitsuka
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka 415 0025, Japan
    Sci Rep 4:5050. 2014
    ..This new method can provide breakthroughs in studying the functions of maternal mRNAs. ..
  46. doi request reprint Efficient TALEN construction and evaluation methods for human cell and animal applications
    Tetsushi Sakuma
    Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 1 3 1 Kagamiyama, Higashi Hiroshima, Hiroshima 739 8526, Japan
    Genes Cells 18:315-26. 2013
    ..Our methods are more time efficient compared with conventional yeast-based evaluation methods and provide a more accessible and effective protocol for the application of TALENs in various model organisms...
  47. doi request reprint Cell type and function of neurons in the ascidian nervous system
    Takeo Horie
    Shimoda Marine Research Center, University of Tsukuba, 5 10 1 Shimoda, Shizuoka, 415 0025, Japan
    Dev Growth Differ 51:207-20. 2009
    ..Thus, the simple nervous system of the ascidian larva can serve as an attractive model system for studying the development, function, and evolution of the chordate nervous system...
  48. doi request reprint Neuronal map reveals the highly regionalized pattern of the juvenile central nervous system of the ascidian Ciona intestinalis
    Akiko Hozumi
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Dev Dyn 244:1375-93. 2015
    ..The neuronal organization of the CNS of ascidian tadpole larvae has been well described, but that in the CNS of postmetamorphosis juveniles has not been characterized well...
  49. ncbi request reprint A cDNA resource from the basal chordate Ciona intestinalis
    Yutaka Satou
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto, Japan
    Genesis 33:153-4. 2002
    ..This release is ready for use in cDNA cloning, micro/macroarray analysis, and other comprehensive genome-wide analyses for further molecular studies of basal chordates...
  50. pmc Switching the rate and pattern of cell division for neural tube closure
    Yosuke Ogura
    Shimoda Marine Research Center, University of Tsukuba, Shimoda, Shizuoka, Japan
    Neurogenesis (Austin) 3:e1235938. 2016
    ..Here we review the developmental regulation of rate and pattern of cell division during NTC with emphasis on the switching mechanism identified in our study...
  51. pmc The conserved Rieske oxygenase DAF-36/Neverland is a novel cholesterol-metabolizing enzyme
    Takuji Yoshiyama-Yanagawa
    Graduate School of Life and Environmental Sciences, University of Tsukuba, Tsukuba, Ibaraki 305 8572, Japan
    J Biol Chem 286:25756-62. 2011
    ..These data suggest that daf-36/nvd genes are functionally orthologous across the bilaterian phylogeny. We propose that the daf-36/nvd family of proteins is a novel conserved player in cholesterol metabolism across the animal phyla...
  52. ncbi request reprint Identification of cis elements which direct the localization of maternal mRNAs to the posterior pole of ascidian embryos
    Yasunori Sasakura
    Department of Zoology, Graduate School of Science, Kyoto University, Sakyo ku, Kyoto 606 8502, Japan
    Dev Biol 250:128-44. 2002
    ..These findings, especially the identification of the small localization element of HrWnt-5 mRNA, provide new insights into the localization of mRNAs during ascidian embryogenesis...
  53. ncbi request reprint The draft genome of Ciona intestinalis: insights into chordate and vertebrate origins
    Paramvir Dehal
    U S Department of Energy Joint Genome Institute, 2800 Mitchell Drive, Walnut Creek, CA 94598, USA
    Science 298:2157-67. 2002
    ..The ascidian genome has also acquired a number of lineage-specific innovations, including a group of genes engaged in cellulose metabolism that are related to those in bacteria and fungi...
  54. pmc The amphioxus genome illuminates vertebrate origins and cephalochordate biology
    Linda Z Holland
    Marine Biology Research Division, Scripps Institution of Oceanography, La Jolla, California 92093 0202, USA
    Genome Res 18:1100-11. 2008
    ..Our results indicate that the amphioxus genome is elemental to an understanding of the biology and evolution of nonchordate deuterostomes, invertebrate chordates, and vertebrates...
  55. doi request reprint Euro chordates: Ascidian community swims ahead. The 4th International Tunicate meeting in Villefranche sur Mer
    Christian Sardet
    BioMarCell, UMR 7009, CNRS UPMC, Station Zoologique, Observatoire Oceanologique, Villefranche sur Mer, France
    Dev Dyn 237:1207-13. 2008
  56. ncbi request reprint Culture of Ciona intestinalis in closed systems
    Jean Stephane Joly
    INRA MSNC Group, DEPSN, UPR2197, Institut Fessard, CNRS, Gif sur Yvette, France
    Dev Dyn 236:1832-40. 2007
    ..Because these systems make it easier to rear Ciona intestinalis in laboratories, they increase the potentialities of this model organism for research...