Deepak Kaul

Summary

Publications

  1. ncbi request reprint Green tea polyphenol inhibits Mycobacterium tuberculosis survival within human macrophages
    Paras K Anand
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Chandigarh 160 012, India
    Int J Biochem Cell Biol 38:600-9. 2006
  2. ncbi request reprint Cellular AATF gene: armour against HIV-1
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Indian J Biochem Biophys 44:276-8. 2007
  3. doi request reprint Regulatory role of miR-2909 in cell-mediated immune response
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Cell Biochem Funct 30:500-4. 2012
  4. doi request reprint Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Blood Cells Mol Dis 55:89-93. 2015
  5. doi request reprint High glucose-induced human cellular immune response is governed by miR-2909 RNomics
    Deepak Kaul
    Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India Department of Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Blood Cells Mol Dis 54:342-7. 2015
  6. doi request reprint MALT1 induced immune response is governed by miR-2909 RNomics
    Deepak Kaul
    Departments of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India Electronic address
    Mol Immunol 64:210-7. 2015
  7. pmc miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias
    Deepti Malik
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cancer 13:175. 2014
  8. doi request reprint Arsenic programmes cellular genomic-immunity through miR-2909 RNomics
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Gene 536:326-31. 2014
  9. ncbi request reprint Cholesterol-sensor initiates M. tuberculosis entry into human macrophages
    D Kaul
    Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 258:219-22. 2004
  10. ncbi request reprint Functional characterization of AATF transcriptome in human leukemic cells
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Mol Cell Biochem 297:215-20. 2007

Collaborators

Detail Information

Publications62

  1. ncbi request reprint Green tea polyphenol inhibits Mycobacterium tuberculosis survival within human macrophages
    Paras K Anand
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Chandigarh 160 012, India
    Int J Biochem Cell Biol 38:600-9. 2006
    ..Based on these results, we propose that epigallocatechin-3-gallate may be of importance in the prevention of tuberculosis infection...
  2. ncbi request reprint Cellular AATF gene: armour against HIV-1
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Indian J Biochem Biophys 44:276-8. 2007
    ....
  3. doi request reprint Regulatory role of miR-2909 in cell-mediated immune response
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Cell Biochem Funct 30:500-4. 2012
    ..Based upon these results, we propose that miR-2909 may modulate native immunity in general and help in providing protective immunity against viral infections in particular...
  4. doi request reprint Mitochondrial uncoupling protein (UCP2) gene expression is regulated by miR-2909
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Blood Cells Mol Dis 55:89-93. 2015
    ....
  5. doi request reprint High glucose-induced human cellular immune response is governed by miR-2909 RNomics
    Deepak Kaul
    Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India Department of Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Blood Cells Mol Dis 54:342-7. 2015
    ..Based upon these results an attempt was also made to propose a mechanistic pathway that links high glucose induced cellular miR-2909 RNomics with the genes involved in energy metabolism and immune response. ..
  6. doi request reprint MALT1 induced immune response is governed by miR-2909 RNomics
    Deepak Kaul
    Departments of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India Electronic address
    Mol Immunol 64:210-7. 2015
    ..Based upon these results, a mechanistic-pathway is proposed that links the epigenomic-interplay between MALT1 and miR-2909. ..
  7. pmc miR-2909-mediated regulation of KLF4: a novel molecular mechanism for differentiating between B-cell and T-cell pediatric acute lymphoblastic leukemias
    Deepti Malik
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cancer 13:175. 2014
    ..The present study investigated the relationship between miR-2909 and Kruppel-like factor 4 (KLF4), and its functional relevance to cell cycle progression and immortalization in patients with pediatric ALL...
  8. doi request reprint Arsenic programmes cellular genomic-immunity through miR-2909 RNomics
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Gene 536:326-31. 2014
    ..Our results for the first time show that cellular miR-2909 RNomics may constitute an innate genomic armour to promote as well as restrict retroviral infection. ..
  9. ncbi request reprint Cholesterol-sensor initiates M. tuberculosis entry into human macrophages
    D Kaul
    Department of Experimental Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 258:219-22. 2004
    ....
  10. ncbi request reprint Functional characterization of AATF transcriptome in human leukemic cells
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Mol Cell Biochem 297:215-20. 2007
    ..Based on these results we propose that AATF gene may be of crucial importance in maintaining the leukemic state of a cell compartment through its ability to initiate cell proliferation coupled with repression of cellular apoptosis...
  11. ncbi request reprint Importance of LXR-alpha transcriptome in the modulation of innate immunity
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Mol Cell Biochem 292:53-7. 2006
    ..Based upon these results we propose that LXR-alpha gene plays a crucial role in the regulation of innate immunity at the genomic level...
  12. ncbi request reprint Functional genomics of PPAR-gamma in human immunomodulatory cells
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    Mol Cell Biochem 290:211-5. 2006
    ..Based on these results, we propose that PPAR-gamma gene has the inherent capacity to influence the lipid mediated inflammation process in atherosclerotic lesions...
  13. doi request reprint Functional genomics of hTERT gene in leukemic myelopoiesis
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 314:19-23. 2008
    ..Based upon these results, we propose that hTERT gene-based drug design may be useful in the treatment of leukemic myelopoiesis...
  14. doi request reprint HIV-1 genome-encoded hiv1-mir-H1 impairs cellular responses to infection
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, PGIMER, Chandigarh, 160 012, India
    Mol Cell Biochem 323:143-8. 2009
    ..Based upon these findings, we propose an "Epigenomic Pathway" through which hiv1-mir-H1 induced AATF gene knockdown within human mononuclear cells initiates their apoptosis...
  15. ncbi request reprint Importance of blood cellular genomic profile in coronary heart disease
    M Iqbal Baba
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India
    J Biomed Sci 13:17-26. 2006
    ..Based on these reported findings, we propose that blood cellular LXRalpha genomic profile has a protective effect against the development of CHD and hence may be of importance in devising synthetic therapeutic drugs for CHD in future...
  16. ncbi request reprint Effect of herbal polyphenols on atherogenic transcriptome
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 278:177-84. 2005
    ..On the basis of these results, we propose for the first time that HPLC purified polyphenolic fraction IV of Tulsi may have a profound antiatherogenic effect...
  17. ncbi request reprint Genomic effect of vitamin 'C' and statins within human mononuclear cells involved in atherogenic process
    D Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Eur J Clin Nutr 59:978-81. 2005
    ....
  18. ncbi request reprint Effect of green tea polyphenols on the genes with atherosclerotic potential
    D Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Phytother Res 18:177-9. 2004
    ..Based upon these results, it is proposed that GTPs have the inherent capacity to inhibit the development of atherosclerotic lesions...
  19. ncbi request reprint Defective RNA-mediated c-myc gene silencing pathway in Burkitt's lymphoma
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Biochem Biophys Res Commun 313:552-4. 2004
    ..Based on these findings we have proposed a novel RNA-mediated c-myc gene regulation pathway that may be responsible for BL...
  20. ncbi request reprint Cholesterol-receptor-mediated genomics in health and disease
    Deepak Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, 160 012, Chandigarh, India
    Trends Mol Med 9:442-9. 2003
    ....
  21. ncbi request reprint Regulation of PPAR-gamma gene in human promyelocytic HL-60 cell line
    D Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, 160 012 Chandigarh, India
    Leuk Res 27:683-6. 2003
    ....
  22. ncbi request reprint Coronin-1A epigenomics governs mycobacterial persistence in tuberculosis
    Deepak Kaul
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    FEMS Microbiol Lett 278:10-4. 2008
    ..tuberculosis to avoid encounter with the harsh environment within the phagocytic vacuole, and how it may provide a novel approach for the prevention and treatment of tuberculosis...
  23. ncbi request reprint Synergistic action of vitamin D and retinoic acid restricts invasion of macrophages by pathogenic mycobacteria
    Paras K Anand
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    J Microbiol Immunol Infect 41:17-25. 2008
    ..We have shown earlier that vitamin D(3) and retinoic acid (RA) down-regulate TACO gene transcription in a dose-dependent manner...
  24. doi request reprint Potential tumor suppressive function of miR-196b in B-cell lineage acute lymphoblastic leukemia
    Suman Bhatia
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Mol Cell Biochem 340:97-106. 2010
    ..Hence miR-196b can be assigned with the tumor suppressor function and can be of therapeutic importance in paving the way toward the treatment of B-cell ALL...
  25. ncbi request reprint Downregulation of TACO gene transcription restricts mycobacterial entry/survival within human macrophages
    Paras K Anand
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160 012, India
    FEMS Microbiol Lett 250:137-44. 2005
    ..tuberculosis is significantly restricted in THP-1 macrophages exposed to CDCA/RA. On the basis of these findings, we propose that the CDCA/RA-dependent pathway may open a new possibility for the treatment of tuberculosis...
  26. doi request reprint LXR-α selectively reprogrammes cancer cells to enter into apoptosis
    Aanchal Mehrotra
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 349:41-55. 2011
    ..On the basis of this study we propose that in near future LXR-α agonist (Withaferin A) may definitely find its use in the therapeutic interventions directed towards the treatment of cancer...
  27. doi request reprint Regulation of cellular Cyclin D1 gene by arsenic is mediated through miR-2909
    M Sharma
    Experimental Medicine and Biotechnology Department, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Gene 522:60-4. 2013
    ....
  28. pmc Receptor Ck-dependent signaling regulates hTERT gene transcription
    Kavleen Sikand
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    BMC Cell Biol 7:2. 2006
    ....
  29. doi request reprint APOBEC3G governs the generation of truncated AATF protein to ensure oncogenic transformation
    Shaveta Sharma
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India
    Cell Biol Int 40:1366-1371. 2016
    ....
  30. doi request reprint Altered levels of LXR-α: crucial implications in the pathogenesis of vitiligo
    Ravinder Kumar
    Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Exp Dermatol 21:853-8. 2012
    ..Higher expression of LXR-α in perilesional skin melanocytes significantly decreases the adhesion, proliferation and matrix metalloproteinases and increases apoptosis...
  31. doi request reprint Functional genomics of blood cellular LXR-alpha gene in human coronary heart disease
    Vivek P Dave
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    J Mol Cell Cardiol 46:536-44. 2009
    ....
  32. ncbi request reprint Crosstalk between RXR, LXR and VDR within blood mononuclear cellular model
    Vivek P Dave
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research Chandigarh, 160 012, India
    Indian J Exp Biol 50:35-40. 2012
    ..Based on these findings, the role of these nuclear receptors could be better understood in various nuclear receptor mediated pathological processes...
  33. doi request reprint E2F-1 RNomics is critical for reprogramming of cancer cells to quiescent state
    Aanchal Mehrotra
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    Int J Cancer 127:849-58. 2010
    ..Furthermore, this pathway may be useful in designing strategies for the treatment of cancer in general and acute lymphoblastic leukemia in particular...
  34. ncbi request reprint Vitamin D3-dependent pathway regulates TACO gene transcription
    Paras K Anand
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Biochem Biophys Res Commun 310:876-7. 2003
    ..Based upon these results, we propose that synergistic action of RA+vitamin D may be of importance in the prevention/control of M. tuberculosis infection...
  35. ncbi request reprint Pathognomonic genetic expression profile within peripheral blood mononuclear cells of rheumatic heart disease patients
    M Iqbal Baba
    Department of Experimental Medicine and Biotechnology, Chandigarh, 160012, India
    Mol Cell Biochem 291:213-7. 2006
    ..Based upon these results, we propose that maintenance of such a pathognomonic transcriptome within blood mononuclear cells may be responsible for the initiation and progression of rheumatic heart disease...
  36. doi request reprint Low plasma levels of cholecalciferol and 13-cis-retinoic acid in tuberculosis: implications in host-based chemotherapy
    Anand Srinivasan
    Department of Pharmacology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Nutrition 29:1245-51. 2013
    ..The aim of this study was to estimate the concentration of cholecalciferol and 13-cis-retinoic acid (RA) in the plasma and pleural fluid of patients with tuberculosis (TB) against controls...
  37. doi request reprint Short-Term Adjuvant Therapy with Terminalia arjuna Attenuates Ongoing Inflammation and Immune Imbalance in Patients with Stable Coronary Artery Disease: In Vitro and In Vivo Evidence
    Divya Kapoor
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    J Cardiovasc Transl Res 8:173-86. 2015
    ..Our data demonstrate the anti-inflammatory and immunomodulatory effects of T. arjuna that may attenuate ongoing inflammation and immune imbalance in medicated CAD subjects...
  38. doi request reprint Functional genomics of tumor suppressor miR-196b in T-cell acute lymphoblastic leukemia
    Suman Bhatia
    Molecular Biology Unit, Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India
    Mol Cell Biochem 346:103-16. 2011
    ..Results of the present study revealed that miR-196b becomes non-functional in T-cell ALL as a consequence of mutations in 3'-UTR of c-myc gene in T-cell ALL cellular models...
  39. ncbi request reprint Molecular link between cholesterol, cytokines and atherosclerosis
    D Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 219:65-71. 2001
    ....
  40. pmc Blood cellular mutant LXR-α protein stability governs initiation of coronary heart disease
    Mansi Arora
    Mansi Arora, Deepak Kaul, Yash Paul Sharma, Department of Experimental Medicine, Biotechnology and Cardiology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    World J Cardiol 5:305-12. 2013
    ....
  41. doi request reprint Functional nature of a novel mutant CYLD observed in pediatric lymphoblastic B-cell leukemia
    Mansi Arora
    Departments of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    Pediatr Blood Cancer 62:1066-9. 2015
    ..Based upon these results, we propose that this mutant CYLD has the capacity to act as a differential marker characteristic of B-cell lymphoblastic leukemia. Pediatr Blood Cancer 2015;62:1066-1069. © 2015 Wiley Periodicals, Inc...
  42. doi request reprint Oncogenic nature of a novel mutant AATF and its interactome existing within human cancer cells
    Shaveta Sharma
    Department of Experimental Medicine and Biotechnology, Molecular Biology Unit, Post Graduate Institute of Medical Education and Research, Chandigarh, 160012, India
    Cell Biol Int 39:326-33. 2015
    ..Hence, the proposed mutant AATF interactome-based pathway can have the inherent ability to ensure human cells become and remain cancerous...
  43. doi request reprint LXR-α genomics programmes neuronal death observed in Alzheimer's disease
    Ashvinder Raina
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Apoptosis 15:1461-9. 2010
    ....
  44. ncbi request reprint Diabetes and tuberculosis: analysis of a paradox
    Dibyajyoti Banerjee
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Adv Clin Chem 53:139-53. 2011
    ..To address this paradox, diabetes and tuberculosis are reviewed at the molecular level...
  45. ncbi request reprint Functional proteomics of receptor-Ck in the developmental stages of human atherosclerotic arterial wall
    D Kaul
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh
    Indian Heart J 55:252-5. 2003
    ..The study was undertaken to understand the relationship between the functional proteomics of receptor-Ck and developmental stages of human atherosclerotic aortic wall...
  46. ncbi request reprint Expression and functional activity of receptor-Ck in mononuclear cells of a homozygous hypercholesterolemic family
    D Kaul
    Department of Experimental Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh
    Indian Heart J 54:88-90. 2002
    ..On the basis of these results, it is tempting to speculate that receptor-Ck may be involved in the maintenance of cellular cholesterol homeostasis observed in homozygous familial hypercholesterolemic patients...
  47. ncbi request reprint Receptor-Ck regulates giardia encystation process
    D Kaul
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Science and Research, Chandigarh, India
    Mol Cell Biochem 225:167-9. 2001
    ..Based upon these findings, we propose that receptor-Ck dependent signalling is responsible for the regulation of giardia encystation process by cholesterol...
  48. doi request reprint Modulation of LXR-α and the effector genes by Ascorbic acid and Statins in psoriatic keratinocytes
    Deepti Soodgupta
    Department of Dermatology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh, 160012, India
    Mol Cell Biochem 397:1-6. 2014
    ..The expression of the VDR and Catalase was significantly increased in both treated keratinocytes compared to its normal counterpart...
  49. doi request reprint Human coronary heart disease: importance of blood cellular miR-2909 RNomics
    Mansi Arora
    Departments of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research PGIMER, Chandigarh, 160012, India
    Mol Cell Biochem 392:49-63. 2014
    ....
  50. doi request reprint Cellular proteolytic modification of tumor-suppressor CYLD is critical for the initiation of human T-cell acute lymphoblastic leukemia
    Mansi Arora
    Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    Blood Cells Mol Dis 54:132-8. 2015
    ..Based upon these results, we propose that MALT1 inhibitors may be of crucial importance in the treatment of T-ALL subjects of pediatric age group...
  51. doi request reprint Combined inhalational and oral supplementation of ascorbic acid may prevent influenza pandemic emergency: a hypothesis
    Dibyajyoti Banerjee
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research PGIMER, Chandigarh, India
    Nutrition 26:128-32. 2010
    ..We have also correlated the clinical and laboratory studies and developed a hypothesis to prevent influenza pandemics...
  52. doi request reprint Inhibitory effects of Terminalia arjuna on platelet activation in vitro in healthy subjects and patients with coronary artery disease
    Namita Malik
    Department of Experimental Medicine and Biotechnology, Chandigarh 160012, India
    Platelets 20:183-90. 2009
    ..Thus, TA can be exploited for its therapeutic potential in CAD and related cardiovascular disorders...
  53. ncbi request reprint RNA-mediated regulation of Receptor-Ck gene in human platelets
    J Singh
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Mol Cell Biochem 173:189-92. 1997
    ....
  54. ncbi request reprint Sterol dependent LDL-receptor gene transcription in lymphocytes from normal and CML patients
    R Goel
    Department of Experimental Medicine and Biotechnology, Chandigarh, India
    Cancer Lett 107:193-8. 1996
    ....
  55. doi request reprint APOBEC3G has the ability to programme T cell plasticity
    Anuradha Garg
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Blood Cells Mol Dis 59:108-12. 2016
    ..On the basis of these findings, we propose that APOBEC3G has the ability to induce T cell plasticity and modulate immune response. ..
  56. doi request reprint APOBEC3G governs to ensure cellular oncogenic transformation
    Anuradha Garg
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India Electronic address
    Blood Cells Mol Dis 55:248-54. 2015
    ....
  57. doi request reprint Interleukin-18-induced atherosclerosis involves CD36 and NF-κB crosstalk in Apo E-/- mice
    Owais Mohammad Bhat
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research PGIMER, Chandigarh, India
    J Cardiol 66:28-35. 2015
    ..The present study proposes a novel role for IL-18 in cholesterol efflux and plaque stability and demonstrates that pyrrolidine dithiocarbamate (PDTC), a NF-κB inhibitor blocks IL-18 signaling in apolipoprotein (Apo) E-/- mice...
  58. doi request reprint AATF RNome has the potential to define post mortem interval
    S Sharma
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India Department of Forensic Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Forensic Sci Int 247:e21-4. 2015
    ..AATF RNome has the potential to act as biomarker for PMI with reasonably good accuracy and hence may turn out to be of crucial importance in forensic investigation. ..
  59. doi request reprint Conventional therapies fail to target inflammation and immune imbalance in subjects with stable coronary artery disease: a system-based approach
    Divya Kapoor
    Department of Experimental Medicine and Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Atherosclerosis 237:623-31. 2014
    ..In spite of improved pharmacological interventions, the clinical outcome or response to therapy is poorly linked with the reversal of signs and symptoms of the disease...
  60. pmc Coronary atherosclerosis: Significance of autophagic armour
    Mansi Arora
    Mansi Arora, Deepak Kaul, Department of Experimental Medicine and Biotechnology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India
    World J Cardiol 4:271-4. 2012
    ....
  61. doi request reprint Development of melanocye-keratinocyte co-culture model for controls and vitiligo to assess regulators of pigmentation and melanocytes
    Ravinder Kumar
    Department of Dermatology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Indian J Dermatol Venereol Leprol 78:599-604. 2012
    ..Therefore to study the biology and pathophysiology of pigmentation and vitiligo, reliable in vitro skin pigmentation models are required...
  62. ncbi request reprint Liver X receptor expression in human melanocytes, does it have a role in the pathogenesis of vitiligo?
    Ravinder Kumar
    Exp Dermatol 19:62-4. 2010
    ..Our present data also revealed that the expression of LXR-alpha at both mRNA and protein level was significantly higher in perilesional skin as compared to the normal skin of vitiligo patient...