Heon Jin Lee

Summary

Affiliation: Kyungpook National University
Country: Korea

Publications

  1. doi request reprint Additional stories of microRNAs
    Heon Jin Lee
    Department of Oral Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 700 412, Korea Brain Science and Engineering Institute, Kyungpook National University, Daegu 700 412, Korea
    Exp Biol Med (Maywood) 239:1275-9. 2014
  2. doi request reprint Exceptional stories of microRNAs
    Heon Jin Lee
    Department of Oral Microbiology, School of Dentistry, Brain Science and Engineering Institute, Kyungpook National University, 2177 Dalgubeol daero, Jung Gu, Daegu 700 412, South Korea
    Exp Biol Med (Maywood) 238:339-43. 2013
  3. pmc Up-regulation of microRNA* strands by their target transcripts
    Sung Min Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, Korea
    Int J Mol Sci 14:13231-40. 2013
  4. doi request reprint Analysis of microRNA-size, small RNAs in Streptococcus mutans by deep sequencing
    Heon Jin Lee
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Korea
    FEMS Microbiol Lett 326:131-6. 2012
  5. doi request reprint EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer
    Jinkyung Kim
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, South Korea Electronic address
    Cancer Lett 349:35-44. 2014
  6. doi request reprint 2-Hydroxycinnamaldehyde inhibits the epithelial-mesenchymal transition in breast cancer cells
    Ismail Ahmed Ismail
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Breast Cancer Res Treat 137:697-708. 2013
  7. doi request reprint Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death
    Hye Sook Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, South Korea
    Cancer Lett 329:217-27. 2013
  8. doi request reprint Identification of microRNA-size, small RNAs in Escherichia coli
    Sung Min Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, 2177 Dalgubeol daero, Jung Gu, Daegu, 700 412, South Korea
    Curr Microbiol 67:609-13. 2013
  9. pmc MicroRNA profiling in the mouse hypothalamus reveals oxytocin-regulating microRNA
    Ji Woong Choi
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Korea
    J Neurochem 126:331-7. 2013
  10. doi request reprint MicroRNA-365 regulates NKX2-1, a key mediator of lung cancer
    Sung Min Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Cancer Lett 335:487-94. 2013

Collaborators

  • Youngkyun Lee
  • Hyo Sang Park
  • Je Yoel Cho
  • Sung Min Kang
  • Su Hyung Hong
  • Byoung Mog Kwon
  • Hye Suk Kang
  • Ji Woong Choi
  • Ismail Ahmed Ismail
  • Jung Tae Lee
  • Hye Sook Kang
  • Hee Don Hwang
  • Tae Geon Kwon
  • Jinkyung Kim
  • Chang Woo Lee
  • Jieun Yun
  • Hyung Lak Kim
  • Hong Moon Jung
  • Jeong Tae Koh
  • Jae Young Kim
  • So Young Choi
  • Jung Hyu Shin
  • Jinkyoung Kim
  • Dong Ki Lee
  • Nicholas A Sanek
  • Hyun Sil Kim
  • W Scott Young
  • Hyeyoun Chang
  • Jiyeon Ock
  • Jong In Yook
  • Nam Hee Kim

Detail Information

Publications20

  1. doi request reprint Additional stories of microRNAs
    Heon Jin Lee
    Department of Oral Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 700 412, Korea Brain Science and Engineering Institute, Kyungpook National University, Daegu 700 412, Korea
    Exp Biol Med (Maywood) 239:1275-9. 2014
    ..miRNA inhibition and intercellular miRNA signaling are also discussed. Taken together, these insights extend current understanding of miRNAs. ..
  2. doi request reprint Exceptional stories of microRNAs
    Heon Jin Lee
    Department of Oral Microbiology, School of Dentistry, Brain Science and Engineering Institute, Kyungpook National University, 2177 Dalgubeol daero, Jung Gu, Daegu 700 412, South Korea
    Exp Biol Med (Maywood) 238:339-43. 2013
    ..Our increasing knowledge of the exceptional stories of miRNAs will offer new insights into these powerful gene regulators from virus and bacteria to animals...
  3. pmc Up-regulation of microRNA* strands by their target transcripts
    Sung Min Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, Korea
    Int J Mol Sci 14:13231-40. 2013
    ..miR-7b* levels were found to significantly increase after transfection of the artificial target. We postulate that the abundance of target transcripts drives miRNA arm selection. ..
  4. doi request reprint Analysis of microRNA-size, small RNAs in Streptococcus mutans by deep sequencing
    Heon Jin Lee
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Korea
    FEMS Microbiol Lett 326:131-6. 2012
    ..mutans, which is one of the principle causative agents of dental caries, has to be elucidated...
  5. doi request reprint EGR1-dependent PTEN upregulation by 2-benzoyloxycinnamaldehyde attenuates cell invasion and EMT in colon cancer
    Jinkyung Kim
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, South Korea Electronic address
    Cancer Lett 349:35-44. 2014
    ..These data showed a critical role of EGR1-PTEN signaling pathway in the EMT of colon cancer, as well as metastasis...
  6. doi request reprint 2-Hydroxycinnamaldehyde inhibits the epithelial-mesenchymal transition in breast cancer cells
    Ismail Ahmed Ismail
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Breast Cancer Res Treat 137:697-708. 2013
    ..This study demonstrates the anti-metastatic effect of the non-toxic natural compound HCA through attenuation of EMT in a breast cancer model...
  7. doi request reprint Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death
    Hye Sook Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, South Korea
    Cancer Lett 329:217-27. 2013
    ..Taken together, our findings suggest that BCA induces prostate cancer cell death via EGR1 upregulation and nuclear translocalization, followed by activation of proapoptotic target genes...
  8. doi request reprint Identification of microRNA-size, small RNAs in Escherichia coli
    Sung Min Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, 2177 Dalgubeol daero, Jung Gu, Daegu, 700 412, South Korea
    Curr Microbiol 67:609-13. 2013
    ..Although, the functional significance of these RNAs is unclear, their high abundance suggests that they may play specialized roles in bacteria, analogous to miRNAs in eukaryotes...
  9. pmc MicroRNA profiling in the mouse hypothalamus reveals oxytocin-regulating microRNA
    Ji Woong Choi
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Korea
    J Neurochem 126:331-7. 2013
    ..These results provide insights into potential neurohypophysial hormone regulation mediated by miRNAs. ..
  10. doi request reprint MicroRNA-365 regulates NKX2-1, a key mediator of lung cancer
    Sung Min Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Cancer Lett 335:487-94. 2013
    ..The NKX2-1 overexpression significantly increased the cell proliferation by overcoming the suppressive effect of miR-365. Our data suggest that miR-365 is an important regulator of NKX2-1 and can be a target for lung cancer therapies...
  11. doi request reprint LRP1-dependent pepsin clearance induced by 2'-hydroxycinnamaldehyde attenuates breast cancer cell invasion
    Hye Suk Kang
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu 700 412, South Korea Global Research Laboratory for RNAi Medicine, Department of Chemistry, Sungkyunkwan University, Suwon 440 746, South Korea
    Int J Biochem Cell Biol 53:15-23. 2014
    ..Furthermore, our data may provide an opportunity to promote the importance of the thiol oxidation status of cell surface receptor proteins for regulating cellular signaling pathways that are important in cancer progression. ..
  12. doi request reprint Soybean extracts facilitate bacterial agglutination and prevent biofilm formation on orthodontic wire
    Heon Jin Lee
    1 Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, Korea
    J Med Food 17:135-41. 2014
    ..mutans biofilm in response to soybean. A possible explanation for these results is that increased agglutination of planktonic streptococci by soybean extracts results in inhibition of bacterial attachment onto the orthodontic wire...
  13. doi request reprint Sequential Treatment with SDF-1 and BMP-2 Potentiates Bone Formation in Calvarial Defects
    Hee Don Hwang
    1 Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Tissue Eng Part A 21:2125-35. 2015
    ..These results suggest that sequential treatment with the cytokines, SDF-1 and BMP-2, may be a promising strategy for accelerating bone regeneration in critical size defects. ..
  14. doi request reprint MicroRNA-124 regulates osteoclast differentiation
    Youngkyun Lee
    Department of Biochemistry, School of Dentistry, Kyungpook National University, Daegu 700 412, Republic of Korea
    Bone 56:383-9. 2013
    ..These findings not only reveal unprecedented role of miR-124 in osteoclastogenesis but also suggest a novel mode of regulation of NFATc1 in osteoclasts. ..
  15. doi request reprint Comparison of gene expression between mandibular and iliac bone-derived cells
    Jung Tae Lee
    Department of Oral and Maxillofacial Surgery, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Clin Oral Investig 19:1223-33. 2015
    ..The purpose of this study is to investigate the differences in gene expression between the human mandibular and iliac bone-derived cells (BCs) for better understanding of the site-specific characteristics of bones...
  16. doi request reprint MicroRNAs in human lung cancer
    Sung Min Kang
    Department of Oral Microbiology and Immunology, School of Dentistry, Kyungpook National University, Daegu 700 412, Korea
    Exp Biol Med (Maywood) 239:1505-13. 2014
    ..Understanding miRNA functions in lung cancer will bring molecular-level insight leading to better prognosis, diagnosis, and therapeutic approaches. ..
  17. doi request reprint Synergistic inhibition of Streptococcal biofilm by ribose and xylitol
    Heon Jin Lee
    Department of Oral Microbiology and Immunology, School of Dentistry, Kyungpook National University, 2 188 1 Samduk dong, Jung Gu, Daegu 700 412, Republic of Korea
    Arch Oral Biol 60:304-12. 2015
    ..These data suggest that pentose may be used as an additive for teeth-protective materials or in sweets. Furthermore, ribose co-treatment with xylitol might help to increase the anti-cariogenic efficacy of xylitol. ..
  18. ncbi request reprint 2'-Benzoyloxycinnamaldehyde-mediated DJ-1 upregulation protects MCF-7 cells from mitochondrial damage
    Ismail Ahmed Ismail
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, Daegu, South Korea
    Biol Pharm Bull 35:895-902. 2012
    ..On the contrary, DJ-1 knockdown in MCF-7 induced MMP perturbation by BCA. These findings suggest that DJ-1 upregulation protects MCF-7 cells from BCA via inhibiting mitochondrial damage...
  19. doi request reprint Quantification of subgingival bacterial pathogens at different stages of periodontal diseases
    Heon Jin Lee
    Department of Oral Microbiology, School of Dentistry, Kyungpook National University, 2 188 1 Samduk dong, Jung Gu, Daegu, South Korea
    Curr Microbiol 65:22-7. 2012
    ..These results suggest that analyzing certain bacterial levels among total oral pathogens may facilitate understanding of the role of periodontal bacteria in the early stages of periodontitis...
  20. doi request reprint Effect of garlic on bacterial biofilm formation on orthodontic wire
    Heon Jin Lee
    Department of Dental Microbiology, School of Dentistry, Kyungpook National University, Daegu, Korea
    Angle Orthod 81:895-900. 2011
    ..To examine the effect of garlic extract on the biofilm formation by Streptococcus mutans on orthodontic wire and on glucosyltransferase gene expression...