W B Alshuaib

Summary

Affiliation: Kuwait University
Country: Kuwait

Publications

  1. ncbi request reprint Effects of alpha-tocopherol on diabetes-induced alterations of synaptic transmission and contractile features in murine dorsiflexor muscle
    M Y Hasan
    Department of Physiology, Faculty of Medicine, UAE University, Al Ain, United Arab Emirates
    Endocr Res 29:419-28. 2003
  2. ncbi request reprint Potassium current in Drosophila neurons is increased by either dunce mutation or cyclic AMP
    W B Alshuaib
    Physiology Department, Faculty of Medicine, Kuwait University, Safat, Kuwait
    J Neurosci Res 52:521-9. 1998
  3. ncbi request reprint Blocking effect of lanthanum on delayed-rectifier K+ current in Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 114:639-50. 2004
  4. ncbi request reprint Pkc-a differentially affects rutabaga and wild-type Drosophila neuronal potassium current
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 114:607-21. 2004
  5. ncbi request reprint Resistance of delayed-rectifier K+ current to cadmium in Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    Int J Neurosci 114:481-91. 2004
  6. ncbi request reprint Inhibition of transient K+ current by copper in Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat
    Neurochem Res 29:785-9. 2004
  7. ncbi request reprint Increased calcium influx through acetylcholine receptors in dunce neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 114:115-28. 2004
  8. ncbi request reprint Serotonin reduces potassium current in rutabaga and wild-type Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 113:1413-25. 2003
  9. ncbi request reprint Drug effects on calcium homeostasis in mouse CA1 hippocampal neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 113:1317-32. 2003
  10. pmc Reduced delayed-rectifier K+ current in the learning mutant rutabaga
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Kuwait
    Learn Mem 9:368-75. 2002

Detail Information

Publications16

  1. ncbi request reprint Effects of alpha-tocopherol on diabetes-induced alterations of synaptic transmission and contractile features in murine dorsiflexor muscle
    M Y Hasan
    Department of Physiology, Faculty of Medicine, UAE University, Al Ain, United Arab Emirates
    Endocr Res 29:419-28. 2003
    ..Alpha-tocopherol exerts a protective role against diabetes-induced peripheral muscle dysfunction. This effect is probably mediated via a free radical scavenging mechanism or modification of Ca2+ homeostasis...
  2. ncbi request reprint Potassium current in Drosophila neurons is increased by either dunce mutation or cyclic AMP
    W B Alshuaib
    Physiology Department, Faculty of Medicine, Kuwait University, Safat, Kuwait
    J Neurosci Res 52:521-9. 1998
    ..Conceivably, altered neuronal excitability in the dunce mutant could disrupt the processing of neural signals necessary for learning and memory...
  3. ncbi request reprint Blocking effect of lanthanum on delayed-rectifier K+ current in Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 114:639-50. 2004
    ..001). Activation and inactivation of IKDR were unchanged by lanthanum. Because these results suggest that lanthanum acts as a potent blocker of IKDR, neuronal excitability may be altered during lanthanum neurotoxicity...
  4. ncbi request reprint Pkc-a differentially affects rutabaga and wild-type Drosophila neuronal potassium current
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 114:607-21. 2004
    ..These results indicate that PKC-A differentially affects the delayed-rectifier channel in wild-type rutabaga...
  5. ncbi request reprint Resistance of delayed-rectifier K+ current to cadmium in Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    Int J Neurosci 114:481-91. 2004
    ..IKDR was similar in the cadmium-containing saline (383 +/- 47 pA) and the control saline (401 +/- 60 pA). These results indicate that cadmium neurotoxicity does not specifically affect IKDR in Drosophila neurons...
  6. ncbi request reprint Inhibition of transient K+ current by copper in Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat
    Neurochem Res 29:785-9. 2004
    ..0 +/- 1.6 pA) than in the control saline (37 +/- 6.5 pA). Activation and inactivation of IK(A) were unchanged by copper. These results suggest that copper can influence neuronal excitability and may affect neuronal function...
  7. ncbi request reprint Increased calcium influx through acetylcholine receptors in dunce neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 114:115-28. 2004
    ....
  8. ncbi request reprint Serotonin reduces potassium current in rutabaga and wild-type Drosophila neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 113:1413-25. 2003
    ..These results indicate that serotonin has affected IKDR so that the inherent difference between the two genotypes was preserved...
  9. ncbi request reprint Drug effects on calcium homeostasis in mouse CA1 hippocampal neurons
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Safat, Kuwait
    Int J Neurosci 113:1317-32. 2003
    ..By contrast, in the presence of aluminum the peak [Ca2+]i was either increased (46%) or it was not affected. These results indicate that neurotoxic drugs could block the entry of calcium into CA1 neurons via VDCC...
  10. pmc Reduced delayed-rectifier K+ current in the learning mutant rutabaga
    Waleed B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, Kuwait
    Learn Mem 9:368-75. 2002
    ..Conceivably, altered neuronal excitability in the rutabaga mutant could disrupt the processing of neural signals necessary for learning and memory...
  11. ncbi request reprint Reduced potassium currents in old rat CA1 hippocampal neurons
    W B Alshuaib
    Department of Physiology, Faculty of Medicine, Kuwait University, P O Box 24923, Safat 13110, Kuwait
    J Neurosci Res 63:176-84. 2001
    ..The age-related reduction in potassium current indicates plasticity in neuronal function that can impact communication in the hippocampal neural network during aging...
  12. ncbi request reprint Progression of visual evoked potential abnormalities in multiple sclerosis and optic neuritis
    W B Alshuaib
    Physiology Department, Faculty of Medicine, Kuwait University
    Electromyogr Clin Neurophysiol 40:243-52. 2000
    ..These results indicate a progression of demyelination in optic neuritis, confirmed MS, and optic neuritis combined with confirmed MS...
  13. ncbi request reprint Early morphological remodeling of neuromuscular junction in a murine model of diabetes
    M A Fahim
    Department of Physiology, Faculty of Medicine, United Arab Emirates University, Al Ain, United Arab Emirates
    J Appl Physiol (1985) 89:2235-40. 2000
    ..These changes are possibly related to alterations in Ca(2+) mobilization across muscle membrane. Other mechanisms such as free radical-mediated actions may also be implicated in STZ-induced effects on skeletal muscle...
  14. ncbi request reprint The impact of vitamin C on diabetes induced alterations at murine neuromuscular junction
    M Y Hasan
    Department of Physiology, Faculty of Medicine, UAE University, Al Ain, United Arab Emirates
    Endocr Res 28:49-59. 2002
    ..6 +/- 0.2 g to 3.9 +/- 0.3 g), impacted delayed half time of decay and increased MEPPs frequencies. Vitamin C improves diabetes-induced nerve and muscle dysfunction possibly via a free radical scavenging mechanism...
  15. ncbi request reprint Effects of ascorbic acid on lead induced alterations of synaptic transmission and contractile features in murine dorsiflexor muscle
    M Y Hasan
    Department of Pharmacology, Faculty of Medicine, UAE University, PO Box 17666, Al Ain, United Arab Emirates
    Life Sci 73:1017-25. 2003
    ..This effect of ascorbic acid on lead induced neuromyopathy is probably mediated via a free radical scavenging mechanism or modification of Ca(2+) homeostasis...
  16. ncbi request reprint alpha-Tocopherol modifies lead induced functional changes at murine neuromuscular junction
    M Y Hasan
    Department of Pharmacology, Faculty of Medicine, UAE University, Al Ain, United Arab Emirates
    Free Radic Res 38:1321-8. 2004
    ..alpha-Tocopherol appears to protect against lead induced neuromuscular dysfunction. These effects of alpha-tocopherol are possibly mediated via a free radical mechanism or modification of calcium homeostasis...