- Alternative mRNA splicing of G protein-coupled receptorsDanijela Markovic
Division of Chemistry and Chemical Engineering, California Institute of Technology, Pasadena, California, USA
Methods Enzymol 520:323-35. 2013..In this chapter, we will describe the methods for detection and quantification of alternatively spliced GPCR mRNA. As the experimental paradigm, we use type 1 corticotropin-releasing hormone receptor (CRH-R1)...
- Characterization of structural determinants of type 1 corticotropin releasing hormone (CRH) receptor signalling propertiesDanijela Markovic
Department of Cell Physiology and Pharmacology, University of Leicester, Leicester, UK
Methods Mol Biol 634:285-307. 2010..We identified a penta-amino acid cassette within the 29-amino acid insert of CRH-R1beta rich in positive charged amino acids (F(170)-R(174)), as an important structural determinant for the impaired cAMP response...