Enrique Espinosa

Summary

Affiliation: Instituto Nacional de Enfermedades Respiratorias
Location: Mexico City, Mexico
Summary:
Researcher in immunopathogenesis of HIV disease, and chronic inflammation in other settings.

Graduate student mentor at Doctorado en Ciencias Biomédicas, National University, Mexico (UNAM)
Grants:
Immune reconstitution inflammatory syndrome: An alteration in CD4+ T regulatory cells and in costimulatory molecules?, 2005, UC-Mexus/ Conacyt, University of California
Reconstitución inmunitaria en VIH: Bases inmunológicas de sus límites y consecuencias, 2006, Conacyt Mexico, 114484 “Polarización de las células T de memoria centrales como biomarcador de riesgo en pacientes en etapa avanzada de la enfermedad por VIH, 2010, Conacyt, Imss, SSa, Issste MEXICO

Publications

  1. doi request reprint Risk factors for immune reconstitution inflammatory syndrome under combination antiretroviral therapy can be aetiology-specific
    E Espinosa
    Center for Infectious Diseases Research CIENI, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosio Villegas, Mexico City, Mexico
    Int J STD AIDS 21:573-9. 2010
  2. ncbi request reprint [Behavior-immunity relationship: the role of cytokines]
    E Espinosa
    , Departamento de Neurociencias, , UNAM,
    Rev Invest Clin 53:240-53. 2001
  3. ncbi request reprint Bevacizumab reverts serous retinal detachment caused by tuberculosis-associated immune reconstitution inflammatory syndrome
    Matilde Ruiz-Cruz
    AIDS 25:1241-3. 2011
  4. pmc Dissociation of CD154 and cytokine expression patterns in CD38+ CD4+ memory T cells in chronic HIV-1 infection
    Enrique Espinosa
    Department of Infectious Diseases Research, National Institute of Respiratory Diseases, Mexico
    J Acquir Immune Defic Syndr 55:439-45. 2010
  5. doi request reprint Novel presentation of immune reconstitution inflammatory syndrome: folliculitis secondary to Malassezia spp
    Gabriela Moreno-Coutiño
    Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Center for Infectious Diseases Research CIENI, Mexico City DF, Mexico Hospital General Manuel Gea González, Dermatology Service, Mexico DF, Mexico
    Mycoses 54:e252-4. 2011
  6. pmc Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study
    Santiago Avila-Ríos
    Center for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
    Retrovirology 6:72. 2009
  7. doi request reprint Later onset of herpes zoster-associated immune reconstitution inflammatory syndrome
    E Espinosa
    Centre for Infectious Diseases Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 4502, 14080 Mexico
    HIV Med 10:454-7. 2009
  8. ncbi request reprint Endoscopic assessment of adenoid size is an indicator of tissue virologic response to highly active antiretroviral therapy
    Enrique Espinosa
    Center for Infectious Diseases Research, National Institute for Respiratory Diseases, Mexico City, Mexico
    J Otolaryngol Head Neck Surg 38:255-60. 2009
  9. doi request reprint Identification of oral candidosis, hairy leukoplakia and recurrent oral ulcers as distinct cases of immune reconstitution inflammatory syndrome
    V A Ramirez-Amador
    Health Care Department, Universidad Autonoma Metropolitana Xochimilco, Mexico City
    Int J STD AIDS 20:259-61. 2009
  10. ncbi request reprint Weakened [corrected] taste-LPS association during endotoxin tolerance
    G Pacheco-Lopez
    Chair of Psychology and Behavioral Immunobiology, Institute for Behavioral Sciences, ETH Zurich, 8092 Zurich, Switzerland
    Physiol Behav 93:261-6. 2008

Collaborators

Detail Information

Publications21

  1. doi request reprint Risk factors for immune reconstitution inflammatory syndrome under combination antiretroviral therapy can be aetiology-specific
    E Espinosa
    Center for Infectious Diseases Research CIENI, Instituto Nacional de Enfermedades Respiratorias, Ismael Cosio Villegas, Mexico City, Mexico
    Int J STD AIDS 21:573-9. 2010
    ..Indicators of advanced HIV disease and subclinical inflammation jointly predict IRIS, and some are specific of the underlying microbial aetiology, possibly explaining previous reports...
  2. ncbi request reprint [Behavior-immunity relationship: the role of cytokines]
    E Espinosa
    , Departamento de Neurociencias, , UNAM,
    Rev Invest Clin 53:240-53. 2001
    ..Possible mechanisms and pathways of communication between the brain and the immune system, as well as the possible participation of other cytokines are discussed...
  3. ncbi request reprint Bevacizumab reverts serous retinal detachment caused by tuberculosis-associated immune reconstitution inflammatory syndrome
    Matilde Ruiz-Cruz
    AIDS 25:1241-3. 2011
  4. pmc Dissociation of CD154 and cytokine expression patterns in CD38+ CD4+ memory T cells in chronic HIV-1 infection
    Enrique Espinosa
    Department of Infectious Diseases Research, National Institute of Respiratory Diseases, Mexico
    J Acquir Immune Defic Syndr 55:439-45. 2010
    ....
  5. doi request reprint Novel presentation of immune reconstitution inflammatory syndrome: folliculitis secondary to Malassezia spp
    Gabriela Moreno-Coutiño
    Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Center for Infectious Diseases Research CIENI, Mexico City DF, Mexico Hospital General Manuel Gea González, Dermatology Service, Mexico DF, Mexico
    Mycoses 54:e252-4. 2011
    ..Here, we describe folliculitis associated with Malassezia spp. as a distinct manifestation of IRIS. The distinction between these two types of IRIS folliculitis is relevant for treatment...
  6. pmc Unique features of HLA-mediated HIV evolution in a Mexican cohort: a comparative study
    Santiago Avila-Ríos
    Center for Research in Infectious Diseases, National Institute of Respiratory Diseases, Mexico City, Mexico
    Retrovirology 6:72. 2009
    ..However, it is not known whether characteristic HLA frequency distributions in different populations have resulted in additional unique footprints...
  7. doi request reprint Later onset of herpes zoster-associated immune reconstitution inflammatory syndrome
    E Espinosa
    Centre for Infectious Diseases Research, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Mexico City 4502, 14080 Mexico
    HIV Med 10:454-7. 2009
    ..The aim of the study was to determine whether immune reconstitution inflammatory syndrome (IRIS) associated with herpes zoster occurs on a different time frame from other instances of IRIS...
  8. ncbi request reprint Endoscopic assessment of adenoid size is an indicator of tissue virologic response to highly active antiretroviral therapy
    Enrique Espinosa
    Center for Infectious Diseases Research, National Institute for Respiratory Diseases, Mexico City, Mexico
    J Otolaryngol Head Neck Surg 38:255-60. 2009
    ..To compare human immunodeficiency virus viral load (HIVVL) in plasma versus the adenoid HIVVL during highly active antiretroviral therapy (HAART)...
  9. doi request reprint Identification of oral candidosis, hairy leukoplakia and recurrent oral ulcers as distinct cases of immune reconstitution inflammatory syndrome
    V A Ramirez-Amador
    Health Care Department, Universidad Autonoma Metropolitana Xochimilco, Mexico City
    Int J STD AIDS 20:259-61. 2009
    ..CD4+ T-cell counts at symptom onset suggested no remaining immune suppression. Our findings show that cases of OC, HL and recurrent ulcers can be instances of IRIS...
  10. ncbi request reprint Weakened [corrected] taste-LPS association during endotoxin tolerance
    G Pacheco-Lopez
    Chair of Psychology and Behavioral Immunobiology, Institute for Behavioral Sciences, ETH Zurich, 8092 Zurich, Switzerland
    Physiol Behav 93:261-6. 2008
    ....
  11. ncbi request reprint [Finding the traces of the HIV selection]
    Enrique Espinosa
    Centro de Investigaciones en Enfermedades Infecciosas CIENI, Instituto Nacional de Enfermedades Respiratorias, Mexico, D F
    Rev Latinoam Microbiol 48:84-90. 2006
    ....
  12. ncbi request reprint Cornering HIV: taking advantage of interactions between selective pressures
    S Avila-Ríos
    Center for Infectious Diseases Research, National Institute of Respiratory Diseases, Calzada de Tlalpan 4502, CP 14080 Mexico City, Mexico
    Med Hypotheses 69:422-31. 2007
    ..Cornering would control HIV infection better than current strategies, focused on few, albeit important, sites in the HIV genome...
  13. ncbi request reprint CD8+ cell noncytotoxic anti-HIV response: restoration by HAART in the late stage of infection
    Klintsy J Torres
    Departamento de Investigación en Enfermedades Infecciosas CIENI, Instituto Nacional de Enfermedades Respiratorias INER, Mexico City, Mexico
    AIDS Res Hum Retroviruses 22:144-52. 2006
    ..Our findings suggest a beneficial effect on CNAR in those individuals with reduced activity, typically in late-stage infection...
  14. ncbi request reprint Lower incidence and severity of cytomegalovirus-associated immune recovery uveitis in HIV-infected patients with delayed highly active antiretroviral therapy
    Gabriela Ortega-Larrocea
    Centro de Investigación en Enfermedades Infecciosas, Instituto Nacional Enfermedades Respiratorias, Mexico City, Mexico
    AIDS 19:735-8. 2005
    ..The findings suggest a protective role of delaying HAART until cytomegalovirus retinitis is controlled...
  15. ncbi request reprint In vitro adrenergic modulation of cellular immune functions in experimental autoimmune encephalomyelitis
    Katharina Haerter
    Department of Medical Psychology, University of Essen Medical School, Hufelandstr 55, 45122 Essen, Germany
    J Neuroimmunol 146:126-32. 2004
    ..To analyze the effects in vitro of alpha- and beta-adrenoceptor agonists on splenocyte proliferation and on proinflammatory cytokine production in splenocytes and peritoneal macrophages (MF) in different stages of EAE...
  16. ncbi request reprint Enhancement of antibody response by one-trial conditioning: contrasting results using different antigens
    Enrique Espinosa
    Department of Neuroscience, Cell Physiology Institute, National Autonomous University of Mexico UNAM, Apartado Postal 70 253, Mexico DF 04510, Mexico
    Brain Behav Immun 18:76-80. 2004
    ..By comparing these and other findings we conclude that the number of conditioning trials is a possible requirement for a more reliable conditioning of antibody response...
  17. ncbi request reprint The role of cortical cholinergic pre- and post-synaptic receptors in taste memory formation
    Leticia Ramirez-Lugo
    Departamento de Neurociencias, Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, C P 04510 Mexico D F, Mexico
    Neurobiol Learn Mem 79:184-93. 2003
    ....
  18. ncbi request reprint Peripheral protein immunization induces rapid activation of the CNS, as measured by c-Fos expression
    Gustavo Pacheco-López
    Instituto de Fisiologia Celular, Universidad Nacional Autonoma de Mexico, A P 70 253, 04510 Cd, Mexico, D F, Mexico
    J Neuroimmunol 131:50-9. 2002
    ..Our results suggest that different interconnected brain cell groups respond rapidly to an immune challenge in the periphery, constituting an afferent pathway of neuroimmune communication...
  19. pmc A transcriptome-based model of central memory CD4 T cell death in HIV infection
    Gustavo Olvera-García
    Department of Research in Immunology, Instituto Nacional de Enfermedades Respiratorias Ismael Cosio Villegas, Calzada de Tlalpan 4502, Mexico City, Mexico
    BMC Genomics 17:956. 2016
    ..We investigated if central memory CD4 T cells from patients with HIV-1 infection have a gene expression profile impeding proliferation and survival, despite their activated state...