Raymond I Ozolua

Summary

Affiliation: University of Benin
Country: Nigeria

Publications

  1. ncbi request reprint Increased superoxide dismutase and Na+, K+-ATPase activities in aortic strips from potassium-adapted rats: implication for altered vascular reactivity
    Raymond I Ozolua
    Department of Pharmacology, Faculty of Pharmacy, University of Benin, P M B 1154, Benin City, Nigeria
    Comp Biochem Physiol C Toxicol Pharmacol 135:61-5. 2003
  2. pmc Evaluation of the protective and ameliorative properties of Garcinia kola on histamine-induced bronchoconstriction in guinea pigs
    Mina T Ibulubo
    Department of Anatomy, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria
    Pharmacognosy Res 4:203-7. 2012
  3. ncbi request reprint Some characteristic relaxant effects of aqueous leaf extract of Andrographis paniculata and andrographolide on guinea pig tracheal rings
    Raymond I Ozolua
    Niger J Physiol Sci 26:119-24. 2011
  4. ncbi request reprint Haematological influences of potassium adaptation in normotensive and renally-hypertensive Wistar rats
    R I Ozolua
    Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeria
    Br J Biomed Sci 59:80-4. 2002
  5. pmc Acute and sub-acute toxicological assessment of the aqueous seed extract of Persea americana mill (Lauraceae) in rats
    Raymond I Ozolua
    Department of Pharmacology and Toxicology University of Benin, Benin City 300001, Nigeria
    Afr J Tradit Complement Altern Med 6:573-8. 2009
  6. ncbi request reprint Effects of sub-chronic oral cyanide on endothelial function in rabbit aortic rings
    R I Ozolu
    Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeria
    Hum Exp Toxicol 26:105-10. 2007
  7. doi request reprint Studies on the anti-asthmatic and antitussive properties of aqueous leaf extract of Bryophyllum pinnatum in rodent species
    Edward O Salami
    Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City 300001, Nigeria
    Asian Pac J Trop Med 6:421-5. 2013
  8. ncbi request reprint Contractile effect of aqueous Pleurotus tuberregium extract on the isolated bovine iris
    Ghalib A Akinlabi
    Department of Optometry, University of Benin, Benin City, Nigeria
    Curr Eye Res 38:353-7. 2013
  9. ncbi request reprint Analgesic activity of aqueous extract of Stereospermum kunthianum (Cham, Sandrine Petit) stem bark
    Fidelis P Ching
    Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Wilberforce Island, Yenagoa, Bayelsa State, Nigeria
    Acta Pol Pharm 66:83-8. 2009
  10. ncbi request reprint Effects of potassium adaptation on blood pressure and pressor responses in normotensive and renal hypertensive Wistar rats
    E K I Omogbai
    Department of Pharmacology and Toxicology, University of Benin, Benin, Nigeria
    Methods Find Exp Clin Pharmacol 27:5-10. 2005

Collaborators

Detail Information

Publications11

  1. ncbi request reprint Increased superoxide dismutase and Na+, K+-ATPase activities in aortic strips from potassium-adapted rats: implication for altered vascular reactivity
    Raymond I Ozolua
    Department of Pharmacology, Faculty of Pharmacy, University of Benin, P M B 1154, Benin City, Nigeria
    Comp Biochem Physiol C Toxicol Pharmacol 135:61-5. 2003
    ..05) in the aortae from the potassium-adapted rats compared to controls. It is concluded that the alteration in vascular smooth muscle reactivity may be due to hyperpolarisation caused by the activities of SOD and Na(+), K(+)-ATPase...
  2. pmc Evaluation of the protective and ameliorative properties of Garcinia kola on histamine-induced bronchoconstriction in guinea pigs
    Mina T Ibulubo
    Department of Anatomy, School of Basic Medical Sciences, University of Benin, Benin City, Nigeria
    Pharmacognosy Res 4:203-7. 2012
    ..Garcinia kola is popularly used in African traditional medicine for the relief of acute bronchoconstrictive episodes...
  3. ncbi request reprint Some characteristic relaxant effects of aqueous leaf extract of Andrographis paniculata and andrographolide on guinea pig tracheal rings
    Raymond I Ozolua
    Niger J Physiol Sci 26:119-24. 2011
    ..It is concluded that andographolide contributes at least in part to the relaxant action of AP on tracheal smooth muscles. The mechanism of action is related to inhibition of Ca2+ influx into tracheal smooth muscle cells...
  4. ncbi request reprint Haematological influences of potassium adaptation in normotensive and renally-hypertensive Wistar rats
    R I Ozolua
    Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeria
    Br J Biomed Sci 59:80-4. 2002
    ....
  5. pmc Acute and sub-acute toxicological assessment of the aqueous seed extract of Persea americana mill (Lauraceae) in rats
    Raymond I Ozolua
    Department of Pharmacology and Toxicology University of Benin, Benin City 300001, Nigeria
    Afr J Tradit Complement Altern Med 6:573-8. 2009
    ..However, the concentration of total proteins was significantly increased in the treated group. In conclusion, the aqueous seed extract of P. americana is safe on sub-acute basis but extremely high doses may not be advisable...
  6. ncbi request reprint Effects of sub-chronic oral cyanide on endothelial function in rabbit aortic rings
    R I Ozolu
    Department of Pharmacology and Toxicology, University of Benin, Benin City, Nigeria
    Hum Exp Toxicol 26:105-10. 2007
    ..There were no significant changes in the studied toxicological indices. We conclude that endothelial compromise is necessary for low-dose sub-chronic cyanide-induced to alter vascular reactivity to NA and ACh...
  7. doi request reprint Studies on the anti-asthmatic and antitussive properties of aqueous leaf extract of Bryophyllum pinnatum in rodent species
    Edward O Salami
    Department of Pharmacology and Toxicology, Faculty of Pharmacy, University of Benin, Benin City 300001, Nigeria
    Asian Pac J Trop Med 6:421-5. 2013
    ..To evaluate the antiasthmatic and antitussive properties of the aqueous leaf extract of Bryophyllum pinnatum (B. pinnatum) (BP) Lam...
  8. ncbi request reprint Contractile effect of aqueous Pleurotus tuberregium extract on the isolated bovine iris
    Ghalib A Akinlabi
    Department of Optometry, University of Benin, Benin City, Nigeria
    Curr Eye Res 38:353-7. 2013
    ..Aqueous extract of Pleurotus tuberregium (PT) has been shown to reduce intraocular pressure (IOP) but the underlying mechanism has not been explained...
  9. ncbi request reprint Analgesic activity of aqueous extract of Stereospermum kunthianum (Cham, Sandrine Petit) stem bark
    Fidelis P Ching
    Department of Pharmacology, Faculty of Basic Medical Sciences, College of Health Sciences, Niger Delta University, Wilberforce Island, Yenagoa, Bayelsa State, Nigeria
    Acta Pol Pharm 66:83-8. 2009
    ..This is a possible rationale for its use in traditional human medicine for pain relief...
  10. ncbi request reprint Effects of potassium adaptation on blood pressure and pressor responses in normotensive and renal hypertensive Wistar rats
    E K I Omogbai
    Department of Pharmacology and Toxicology, University of Benin, Benin, Nigeria
    Methods Find Exp Clin Pharmacol 27:5-10. 2005
    ..We conclude that potassium adaptation reduces BP in the normotensive and hypertensive rats and may influence both the degree and duration of action of vasoactive drugs given as bolus injections...
  11. ncbi request reprint Effects of aqueous leaf extract of Bryophyllum pinnatum on guinea pig tracheal ring contractility
    Raymond I Ozolua
    Department of Pharmacology and Toxicology, University of Benin, P M B 1154, Benin City 300001, Nigeria
    Niger J Physiol Sci 25:149-57. 2010
    ..It is concluded that aqueous leaf extract of B. pinnatum possesses antispasmodic effects on the guinea pig tracheal rings. The results lend credence to the use of the extract for the prophylaxis of asthma in ethnomedicine...