S O Mikalsen

Summary

Affiliation: University of Oslo
Country: Norway

Publications

  1. ncbi request reprint A characterization of pervanadate, an inducer of cellular tyrosine phosphorylation and inhibitor of gap junctional intercellular communication
    S O Mikalsen
    Laboratory for Environmental and Occupational Cancer, Norwegian Radium Hospital, Oslo, Norway
    Biochim Biophys Acta 1290:308-18. 1996
  2. ncbi request reprint Induction of phosphotyrosine in the gap junction protein, connexin43
    S O Mikalsen
    Laboratory for Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo
    FEBS Lett 401:271-5. 1997
  3. ncbi request reprint A characterization of permolybdate and its effect on cellular tyrosine phosphorylation, gap junctional intercellular communication and phosphorylation status of the gap junction protein, connexin43
    S O Mikalsen
    Department for Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo
    Biochim Biophys Acta 1356:207-20. 1997
  4. ncbi request reprint Properties of pervanadate and permolybdate. Connexin43, phosphatase inhibition, and thiol reactivity as model systems
    S O Mikalsen
    Department of Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, N 0310 Oslo, Norway
    J Biol Chem 273:10036-45. 1998
  5. ncbi request reprint Morphological transformation and effect on gap junction intercellular communication in Syrian hamster embryo cells as screening tests for carcinogens devoid of mutagenic activity
    E Rivedal
    Department of Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, N 0310, Oslo, Norway
    Toxicol In Vitro 14:185-92. 2000
  6. ncbi request reprint Effects of five phorbol esters on gap junctional intercellular communication, morphological transformation and epidermal growth factor binding in Syrian hamster embryo cells
    T Husøy
    Department for Environmental and Occupational Cancer, Norwegian Radium Hospital, Oslo
    Carcinogenesis 14:73-7. 1993
  7. ncbi request reprint Pharmacological evidence for system-dependent involvement of protein kinase C isoenzymes in phorbol ester-suppressed gap junctional communication
    V Cruciani
    Department of Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, N-0310 Oslo, Norway
    Exp Cell Res 268:150-61. 2001
  8. ncbi request reprint Stimulated phosphorylation of intracellular connexin43
    V Cruciani
    Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, N 0310, Norway
    Exp Cell Res 251:285-98. 1999
  9. ncbi request reprint The vertebrate connexin family
    V Cruciani
    The Norwegian Radium Hospital, Institute for Cancer Research, 0310, Oslo, Norway
    Cell Mol Life Sci 63:1125-40. 2006

Collaborators

Detail Information

Publications9

  1. ncbi request reprint A characterization of pervanadate, an inducer of cellular tyrosine phosphorylation and inhibitor of gap junctional intercellular communication
    S O Mikalsen
    Laboratory for Environmental and Occupational Cancer, Norwegian Radium Hospital, Oslo, Norway
    Biochim Biophys Acta 1290:308-18. 1996
    ..All the studied biological parameters were reversible, also under continuous exposure to pervanadate...
  2. ncbi request reprint Induction of phosphotyrosine in the gap junction protein, connexin43
    S O Mikalsen
    Laboratory for Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo
    FEBS Lett 401:271-5. 1997
    ..This is the first observation of tyrosine phosphorylation of connexins in normal cells...
  3. ncbi request reprint A characterization of permolybdate and its effect on cellular tyrosine phosphorylation, gap junctional intercellular communication and phosphorylation status of the gap junction protein, connexin43
    S O Mikalsen
    Department for Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, Oslo
    Biochim Biophys Acta 1356:207-20. 1997
    ..The biological activities of permolybdate were only partially mimicked by phenylarsine oxide, an alternative protein tyrosine phosphatase inhibitor...
  4. ncbi request reprint Properties of pervanadate and permolybdate. Connexin43, phosphatase inhibition, and thiol reactivity as model systems
    S O Mikalsen
    Department of Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, N 0310 Oslo, Norway
    J Biol Chem 273:10036-45. 1998
    ..Mathematical modeling of the thiol reactivity suggested that monoperoxovanadate at maximum could possess 20% of the biological activity of diperoxovanadate...
  5. ncbi request reprint Morphological transformation and effect on gap junction intercellular communication in Syrian hamster embryo cells as screening tests for carcinogens devoid of mutagenic activity
    E Rivedal
    Department of Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, N 0310, Oslo, Norway
    Toxicol In Vitro 14:185-92. 2000
    ..The data suggest that the combined use of morphological transformation and gap junction intercellular communication in Syrian hamster embryo cells may be beneficial when screening for non-genotoxic carcinogens...
  6. ncbi request reprint Effects of five phorbol esters on gap junctional intercellular communication, morphological transformation and epidermal growth factor binding in Syrian hamster embryo cells
    T Husøy
    Department for Environmental and Occupational Cancer, Norwegian Radium Hospital, Oslo
    Carcinogenesis 14:73-7. 1993
    ..The results do not suggest a simple relationship between PKC activation, inhibition of GJIC and the reported tumor-promoting activities of the compounds...
  7. ncbi request reprint Pharmacological evidence for system-dependent involvement of protein kinase C isoenzymes in phorbol ester-suppressed gap junctional communication
    V Cruciani
    Department of Environmental and Occupational Cancer, Institute for Cancer Research, The Norwegian Radium Hospital, N-0310 Oslo, Norway
    Exp Cell Res 268:150-61. 2001
    ..Furthermore, the use of isotype-specific inhibitors of protein kinase C indicated that protein kinase C alpha, delta, and epsilon may be involved to different extents in different fibroblastic systems in the response to phorbol esters...
  8. ncbi request reprint Stimulated phosphorylation of intracellular connexin43
    V Cruciani
    Institute for Cancer Research, The Norwegian Radium Hospital, Oslo, N 0310, Norway
    Exp Cell Res 251:285-98. 1999
    ..Also, in cells treated with brefeldin A for 8 h, in which the majority of connexin43 was intracellular, phosphorylation was induced by the agents. Phosphorylation of intracellular connexin43 can therefore be induced by several stimuli...
  9. ncbi request reprint The vertebrate connexin family
    V Cruciani
    The Norwegian Radium Hospital, Institute for Cancer Research, 0310, Oslo, Norway
    Cell Mol Life Sci 63:1125-40. 2006
    ..As judged from the recently defined connexins in tunicates, the original connexin might be related to the ortholog groups of Cx36, 39.2, 43.4, 45 or 47...