Beata Sarecka-Hujar

Summary

Affiliation: Medical University
Country: Poland

Publications

  1. ncbi request reprint The TT genotype of the MTHFR 677C > T polymorphism increases susceptibility to premature coronary artery disease in interaction with some of the traditional risk factors
    Beata Sarecka-Hujar
    Department of Applied Pharmacy, Medical University of Silesia, Sosnowiec, Poland
    Acta Medica (Hradec Kralove) 55:172-9. 2012
  2. pmc The TT genotype of methylenetetrahydrofolate reductase 677C>T polymorphism increases the susceptibility to pediatric ischemic stroke: meta-analysis of the 822 cases and 1,552 controls
    Beata Sarecka-Hujar
    Department of Applied Pharmacy, Medical University of Silesia, Kasztanowa Str 3, 41 200 Sosnowiec, Poland
    Mol Biol Rep 39:7957-63. 2012
  3. ncbi request reprint [Role of the polymorphisms within genes encoding proteins related to endothelial dysfunction in coronary artery disease]
    Beata Sarecka-Hujar
    Katedra Farmacji Stosowanej, Zakład Technologii Postaci Leku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej, Slaski Uniwersytet Medyczny w Katowicach
    Wiad Lek 64:294-300. 2011
  4. ncbi request reprint Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease
    Beata Sarecka-Hujar
    Department of Biochemistry and Medical Genetics, School of Health Care, Medical University of Silesia, Katowice, Poland
    Kardiol Pol 66:1269-77. 2008
  5. doi request reprint Interactions between rs5498 polymorphism in the ICAM1 gene and traditional risk factors influence susceptibility to coronary artery disease
    Beata Sarecka-Hujar
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Clin Exp Med 9:117-24. 2009
  6. doi request reprint Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
    Beata Sarecka
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Clin Biochem 41:467-73. 2008
  7. doi request reprint Association analysis of the E-selectin 98G > T polymorphism and the risk of childhood ischemic stroke
    Beata Sarecka-Hujar
    Department of Applied Pharmacy, Medical University of Silesia, Sosnowiec, Poland
    Cell Biochem Funct 28:591-6. 2010
  8. ncbi request reprint Contemporaneous carrier-state of two or three "proatherosclerotic" variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Clin Chim Acta 362:110-8. 2005
  9. doi request reprint The T allele of the 677C>T polymorphism of methylenetetrahydrofolate reductase gene is associated with an increased risk of ischemic stroke in Polish children
    Iwona Zak
    Department of Biochemistry and Medical Genetics, School of Health Care in Katowice, Medical University of Silesia, Katowice, Poland
    J Child Neurol 24:1262-7. 2009
  10. doi request reprint Synergistic effects between 561A > C and 98G > T polymorphisms of E-selectin gene and hypercholesterolemia in determining the susceptibility to coronary artery disease
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Heart Vessels 23:257-63. 2008

Detail Information

Publications17

  1. ncbi request reprint The TT genotype of the MTHFR 677C > T polymorphism increases susceptibility to premature coronary artery disease in interaction with some of the traditional risk factors
    Beata Sarecka-Hujar
    Department of Applied Pharmacy, Medical University of Silesia, Sosnowiec, Poland
    Acta Medica (Hradec Kralove) 55:172-9. 2012
    ..The presence of several risk factors (genetic and non-genetic) has greater impact on the risk of premature coronary artery disease (CAD) than single risk factor...
  2. pmc The TT genotype of methylenetetrahydrofolate reductase 677C>T polymorphism increases the susceptibility to pediatric ischemic stroke: meta-analysis of the 822 cases and 1,552 controls
    Beata Sarecka-Hujar
    Department of Applied Pharmacy, Medical University of Silesia, Kasztanowa Str 3, 41 200 Sosnowiec, Poland
    Mol Biol Rep 39:7957-63. 2012
    ..The results based on a sizeable group of cases and controls have proved that the 677C>T polymorphism in MTHFR gene is associated with the development of ischemic stroke in children...
  3. ncbi request reprint [Role of the polymorphisms within genes encoding proteins related to endothelial dysfunction in coronary artery disease]
    Beata Sarecka-Hujar
    Katedra Farmacji Stosowanej, Zakład Technologii Postaci Leku, Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej, Slaski Uniwersytet Medyczny w Katowicach
    Wiad Lek 64:294-300. 2011
    ..The 1405A>G polymorphism in ICAM1 gene may affect mRNA splicing patterns that modify cell-cell interactions and influence inflammatory response...
  4. ncbi request reprint Carrier-state of two or three polymorphic variants of MTHFR, IL-6 and ICAM1 genes increases the risk of coronary artery disease
    Beata Sarecka-Hujar
    Department of Biochemistry and Medical Genetics, School of Health Care, Medical University of Silesia, Katowice, Poland
    Kardiol Pol 66:1269-77. 2008
    ..Polymorphic variants of genes encoding proteins involved in endothelium dysfunction or proinflammatory state may genetically differentiate the human population and determine a susceptibility to the disease...
  5. doi request reprint Interactions between rs5498 polymorphism in the ICAM1 gene and traditional risk factors influence susceptibility to coronary artery disease
    Beata Sarecka-Hujar
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Clin Exp Med 9:117-24. 2009
    ..28) increasing the risk of CAD. There is a synergistic interaction between rs5498 genotype and smoking that increases the risk of CAD...
  6. doi request reprint Synergistic effects of the polymorphisms in the PAI-1 and IL-6 genes with smoking in determining their associated risk with coronary artery disease
    Beata Sarecka
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow Str 18, 40 752 Katowice, Poland
    Clin Biochem 41:467-73. 2008
    ..To assess the relationship between IL-6 and PAI-1 polymorphisms and coronary artery disease (CAD) and to observe the interactions between these polymorphic variants and smoking in the CAD risk...
  7. doi request reprint Association analysis of the E-selectin 98G > T polymorphism and the risk of childhood ischemic stroke
    Beata Sarecka-Hujar
    Department of Applied Pharmacy, Medical University of Silesia, Sosnowiec, Poland
    Cell Biochem Funct 28:591-6. 2010
    ..32%). In conclusion, we did not confirm the relationship between the 98G > T polymorphism of the E-selectin gene and childhood ischemic stroke. There is still a need for further studies...
  8. ncbi request reprint Contemporaneous carrier-state of two or three "proatherosclerotic" variants of APOE, ICAM1, PPARA and PAI-1 genes differentiate CAD patients from healthy individuals
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Clin Chim Acta 362:110-8. 2005
    ....
  9. doi request reprint The T allele of the 677C>T polymorphism of methylenetetrahydrofolate reductase gene is associated with an increased risk of ischemic stroke in Polish children
    Iwona Zak
    Department of Biochemistry and Medical Genetics, School of Health Care in Katowice, Medical University of Silesia, Katowice, Poland
    J Child Neurol 24:1262-7. 2009
    ..023, odds ratio = 3.09). The T allele was significantly transmitted in male patients (P < .019). We conclude that the MTHFR 677C>T polymorphism may be considered as a genetic risk factor of childhood stroke, especially in boys...
  10. doi request reprint Synergistic effects between 561A > C and 98G > T polymorphisms of E-selectin gene and hypercholesterolemia in determining the susceptibility to coronary artery disease
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Heart Vessels 23:257-63. 2008
    ..The present study points to synergistic interactions between 561A > C or 98G > T polymorphisms of E-selectin gene and hypercholesterolemia that cause a significant increase in the susceptibility to CAD...
  11. ncbi request reprint Carrier-state of D allele in ACE gene insertion/deletion polymorphism is associated with coronary artery disease, in contrast to the C677-->T transition in the MTHFR gene
    Iwona Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Medykow 18, 40 752 Katowice, Poland
    Acta Biochim Pol 50:527-34. 2003
    ..Our data indicate that in Silesian CAD patients the disease is strongly associated with carrier-state of the ACE D allele, but not with the C677-->T transition in the MTHFR gene...
  12. ncbi request reprint Cigarette smoking, carrier state of A or G allele of 46A>G and 79C>G polymorphisms of beta2-adrenergic receptor gene, and the risk of coronary artery disease
    Iwnoa Zak
    Department of Biochemistry and Medical Genetics, Medical University of Silesia, Katowice, Poland
    Kardiol Pol 66:380-6; discussion 387. 2008
    ..The 46A>G and 79C>G polymorphisms of the beta2-adrenergic receptor gene (ADRB2) have been associated with altered response to sympathetic stimulation...
  13. doi request reprint The role of biochemical risk factors in the etiology of AIS in children and adults
    Ilona Kopyta
    a School of Medicine in Katowice, Medical University of Silesia, Department of Paediatrics and Developmental Age Neurology, Chair of Paediatrics, Katowice, Poland
    Int J Neurosci 125:875-84. 2015
    ....
  14. doi request reprint Retracted: Post-stroke epilepsy in Polish paediatric patients
    Ilona Kopyta
    Department of Neuropediatrics, School of Medicine, Medical University of Silesia, Katowice, Poland
    Dev Med Child Neurol 57:780-5. 2015
    ..The retraction has been agreed due to several errors in the statistics. These errors make interpretation of the data difficult and the validity of the conclusions questionable. ..
  15. doi request reprint Post-stroke epilepsy in Polish paediatric patients
    Ilona Kopyta
    Department of Paediatrics and Developmental Age Neurology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland
    Dev Med Child Neurol 57:821-8. 2015
    ..The aim of this study was to characterize a group of children with early and late remote seizures, which occurred after arterial ischaemic stroke (AIS), and to find predictors of post-stroke seizures...
  16. doi request reprint The role of genetic risk factors in arterial ischemic stroke in pediatric and adult patients: a critical review
    Ilona Kopyta
    Department of Neuropediatrics, Medical University of Silesia, ul Medykow 16, 40 752, Katowice, Poland
    Mol Biol Rep 41:4241-51. 2014
    ....
  17. doi request reprint Clinical and radiologic features of unilateral and bilateral schizencephaly in polish pediatric patients
    Ilona Kopyta
    1Department of Neuropediatrics, Medical University of Silesia, Katowice, Poland
    J Child Neurol 29:442-9. 2014
    ..002, r = 0.578). There is a correlation between the type of schizencephaly and the presence of seizures in Polish pediatric patients. In most of the patients, schizencephaly leads to developmental retardation and epileptic seizures...