Katarzyna Winczyk

Summary

Country: Poland

Publications

  1. ncbi request reprint Immunohistochemical detection of PPARgamma receptors in the human pituitary adenomas: correlation with PCNA
    Katarzyna Winczyk
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University, Lodz, Poland
    Folia Histochem Cytobiol 43:137-41. 2005
  2. ncbi request reprint [The role of peroxisome proliferators-activated receptors (PPARgamma) in neoplasms of endocrine glands]
    Katarzyna Winczyk
    Zakład Neuroendokrynologii, Katedra Endokrynologii, Uniwersytet Medyczny, Lodz, Poland
    Endokrynol Pol 59:156-66. 2008
  3. ncbi request reprint Effects of rosiglitazone--peroxisome proliferators-activated receptor gamma (PPARgamma) agonist on cell viability of human pituitary adenomas in vitro
    Katarzyna Winczyk
    Department of Neuroendocrinology, Medical University of Łódź, Łódź, Poland
    Neuro Endocrinol Lett 30:107-10. 2009
  4. ncbi request reprint Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitro
    Katarzyna Winczyk
    Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
    Neuro Endocrinol Lett 30:657-62. 2009
  5. ncbi request reprint Effects of melatonin and melatonin receptors ligand N-[(4-methoxy-1H-indol-2-yl)methyl]propanamide on murine Colon 38 cancer growth in vitro and in vivo
    Katarzyna Winczyk
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Lodz, Poland
    Neuro Endocrinol Lett 23:50-4. 2002
  6. ncbi request reprint Expression of melatonin MT(1) and MT(2) receptors, and ROR alpha(1) receptor in transplantable murine Colon 38 cancer
    Michal Karasek
    Laboratory of Electron Microscopy, Chair of Pathology, Medical University of Lodz, Lodz, Poland
    Neuro Endocrinol Lett 23:55-60. 2002
  7. ncbi request reprint Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells
    Katarzyna Winczyk
    Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
    Neuro Endocrinol Lett 27:351-4. 2006
  8. ncbi request reprint 'Silent' somatotropinoma
    Marek Pawlikowski
    Department of Neuroendocrinology, Chair of Laboratory Medicine, Medical University of Lodz, Poland
    Endokrynol Pol 63:88-91. 2012
  9. ncbi request reprint Possible involvement of the nuclear RZR/ROR-alpha receptor in the antitumor action of melatonin on murine Colon 38 cancer
    Katarzyna Winczyk
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Lodz, Poland
    Tumour Biol 23:298-302. 2002
  10. ncbi request reprint Expression of somatostatin receptor subtypes in primary and recurrent gonadotropinomas: are somatostatin receptors involved in pituitary adenoma recurrence?
    Hanna Pisarek
    Department of Neuroendocrinology, Medical University of Łódź, Poland
    Neuro Endocrinol Lett 32:96-101. 2011

Collaborators

Detail Information

Publications27

  1. ncbi request reprint Immunohistochemical detection of PPARgamma receptors in the human pituitary adenomas: correlation with PCNA
    Katarzyna Winczyk
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University, Lodz, Poland
    Folia Histochem Cytobiol 43:137-41. 2005
    ..The strong expression of PPARgamma in human pituitary adenomas and its possible involvement in control of cell proliferation in these tumors give a good reason for the attempts of their treatment with PPARgamma ligands...
  2. ncbi request reprint [The role of peroxisome proliferators-activated receptors (PPARgamma) in neoplasms of endocrine glands]
    Katarzyna Winczyk
    Zakład Neuroendokrynologii, Katedra Endokrynologii, Uniwersytet Medyczny, Lodz, Poland
    Endokrynol Pol 59:156-66. 2008
    ..In the present paper the structure, tissue expression and biological function of PPARgamma are presented. The reports about oncostatic effects of PPARgamma agonists in pituitary adenomas, thyroid cancers and adrenal tumor are reviewed...
  3. ncbi request reprint Effects of rosiglitazone--peroxisome proliferators-activated receptor gamma (PPARgamma) agonist on cell viability of human pituitary adenomas in vitro
    Katarzyna Winczyk
    Department of Neuroendocrinology, Medical University of Łódź, Łódź, Poland
    Neuro Endocrinol Lett 30:107-10. 2009
    ..The aim of the present study was to examine the anti-tumour effect of RGZ on human pituitary adenomas in vitro...
  4. ncbi request reprint Luzindole but not 4-phenyl-2- propionamidotetralin (4P-PDOT) diminishes the inhibitory effect of melatonin on murine Colon 38 cancer growth in vitro
    Katarzyna Winczyk
    Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
    Neuro Endocrinol Lett 30:657-62. 2009
    ....
  5. ncbi request reprint Effects of melatonin and melatonin receptors ligand N-[(4-methoxy-1H-indol-2-yl)methyl]propanamide on murine Colon 38 cancer growth in vitro and in vivo
    Katarzyna Winczyk
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Lodz, Poland
    Neuro Endocrinol Lett 23:50-4. 2002
    ....
  6. ncbi request reprint Expression of melatonin MT(1) and MT(2) receptors, and ROR alpha(1) receptor in transplantable murine Colon 38 cancer
    Michal Karasek
    Laboratory of Electron Microscopy, Chair of Pathology, Medical University of Lodz, Lodz, Poland
    Neuro Endocrinol Lett 23:55-60. 2002
    ..Therefore, the aim of the present study was to determine whether the membrane melatonin receptors MT(1) and MT(2) as well as the nuclear receptor RZR/ROR alpha are expressed in Colon 38 cells...
  7. ncbi request reprint Growth-inhibitory action of melatonin and thiazolidinedione derivative CGP 52608 on murine 16/C breast cancer cells
    Katarzyna Winczyk
    Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
    Neuro Endocrinol Lett 27:351-4. 2006
    ..The aim of present study was to investigate effects of melatonin, the selective ligand for nuclear RZR/ROR receptors - CGP 52608, and methotrexate on growth of murine 16/C breast cancer cells...
  8. ncbi request reprint 'Silent' somatotropinoma
    Marek Pawlikowski
    Department of Neuroendocrinology, Chair of Laboratory Medicine, Medical University of Lodz, Poland
    Endokrynol Pol 63:88-91. 2012
    ..However, recent data has indicated that they are more frequent than previously thought. The present paper shows that pituitary adenomas, diagnosed before surgery as nonfunctioning, often display GH immunopositivity...
  9. ncbi request reprint Possible involvement of the nuclear RZR/ROR-alpha receptor in the antitumor action of melatonin on murine Colon 38 cancer
    Katarzyna Winczyk
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Lodz, Poland
    Tumour Biol 23:298-302. 2002
    ..Given alone, MLT strongly lowered the P/A ratio, and addition of CGP to MLT abolished the effect of MLT on the P/A ratio. Based on our data, we conclude that nuclear RZR/RORalpha receptors participate in the oncostatic action of MLT...
  10. ncbi request reprint Expression of somatostatin receptor subtypes in primary and recurrent gonadotropinomas: are somatostatin receptors involved in pituitary adenoma recurrence?
    Hanna Pisarek
    Department of Neuroendocrinology, Medical University of Łódź, Poland
    Neuro Endocrinol Lett 32:96-101. 2011
    ..As somatostatin receptors mediate antiproliferative, anti-angiogenic and pro-apoptotic actions, it seemed reasonable to investigate their expression in dependence on the adenoma recurrence...
  11. ncbi request reprint Does the response of GH-secreting pituitary adenomas to octreotide depend on the cellular localization of the somatostatin receptor subtypes SSTR2 and SSTR5?
    Hanna Pisarek
    Department of Neuroendocrinology, Medical University, Łódź
    Endokrynol Pol 61:178-81. 2010
    ..In this study we searched for the relationship between the GH inhibitory response to acute octreotide administration and SSTR2A, SSTR2B, and SSTR5 cellular localization...
  12. ncbi request reprint Proliferating cell nuclear antigen (PCNA) expression in pituitary adenomas: relationship to the endocrine phenotype of adenoma
    Marek Pawlikowski
    Department of Neuroendocrinology, Medical University, Lodz, Poland
    Folia Histochem Cytobiol 44:37-41. 2006
    ..These findings suggest that the proliferative potential of pituitary adenomas is related to the tumor recurrence and hormone expression...
  13. doi request reprint Expression of follicle stimulating hormone receptors in pituitary adenomas - a marker of tumour aggressiveness?
    Marek Pawlikowski
    Department of Immunoendocrinology, Medical University of Lodz, Poland
    Endokrynol Pol 65:469-71. 2014
    ..The aim of the present paper was to provide more detailed data on FSHR expression in different subtypes of pituitary adenomas and to evaluate its possible role as a prognostic and/ or predictive biomarker in these tumours...
  14. pmc Ectopic expression of follicle-stimulating hormone receptors in thyroid tumors
    Marek Pawlikowski
    Department of Immunoendocrinology, Chair of Endocrinology, Medical University of Lodz, Lodz, Poland
    Arch Med Sci 11:1314-7. 2015
    ..However, recently we have found FSHR immunostaining in pituitary adenomas, adrenal tumors and neuroendocrine tumors (carcinoids). The aim of this study was to determine whether the same occurs in thyroid tumors...
  15. ncbi request reprint The detection of macroprolactin by precipitation and ultrafiltration methods
    Karolina Beda-Maluga
    Department of Neuroendocrinology, Medical University of Lodz, Poland
    Endokrynol Pol 62:529-36. 2011
    ..The aim of this study was to evaluate the occurrence of MaPRL in hyperprolactinaemic patients and to compare the results obtained by precipitation and ultrafiltration...
  16. ncbi request reprint Ultrastructure of pinealocytes in mice implanted with Colon 38 adenocarcinoma
    Michal Karasek
    Department of Electron Microscopy, Medical University of Lodz, Poland
    Neuro Endocrinol Lett 24:269-73. 2003
    ..However, morphological studies of the pineal gland in animals with experimentally-induced tumors are rare. Therefore, we decided to investigate the ultrastructure of pinealocytes in mice with implanted Colon 38 adenocarcinoma...
  17. doi request reprint Differential expression of somatostatin receptor subtype-related genes and proteins in non-functioning and functioning adrenal cortex adenomas
    Hanna Pisarek
    Department of Neuroendocrinology, Medical University of Łódź, Łódź 91 425, Poland
    Mol Med Rep 4:963-9. 2011
    ..Messenger RNA detection alone is not sufficient to predict the presence of the receptor protein acting as a target for SST and its analogs...
  18. doi request reprint Immunohistochemical detection of prothymosin alpha in pituitary adenomas--a new marker of tumor recurrence?
    Marek Pawlikowski
    Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Łódź, Łódź, Poland
    Folia Histochem Cytobiol 47:559-62. 2009
    ..However, this conclusion needs to be confirmed in further prospective studies. Moreover, PT alpha may be also useful as an immunohistochemical marker of the intratumoral microvasculature...
  19. doi request reprint Serotonin and melatonin secretion in postmenopausal women with eating disorders
    Cezary Chojnacki
    Departament of Clinical Nutrition and Gastroenterological Diagnostics, Medical University, Lodz, Poland
    Endokrynol Pol 67:299-304. 2016
    ..Postmenopausal women manifest emotional disorders associated with an increase in appetite. The aim of the study was to assess the serotonin and melatonin secretion and metabolism in postmenopausal women in relation to eating disorders...
  20. ncbi request reprint Immunohistochemical detection of dopamine D2 receptors in neuroendocrine tumours
    Marek Pawlikowski
    Department of Neuroendocrinology, Medical University of Lodz, Poland
    Endokrynol Pol 62:388-91. 2011
    ..Moreover, successful trials of the treatment of NET with cabergoline - D2 agonist, have been reported. These findings increase the interest of investigating RD2 expression in NET...
  21. ncbi request reprint Immunohistochemical demonstration of nitric oxide synthase (NOS) in the normal rat pituitary gland, estrogen-induced rat pituitary tumor and human pituitary adenomas
    Marek Pawlikowski
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University, Lodz, Poland
    Folia Histochem Cytobiol 41:87-90. 2003
    ..NOS immunoreactivity is also detectable in all but two human pituitary adenomas and seems to negatively correlate with microvascularization...
  22. ncbi request reprint Serotonin and melatonin secretion and metabolism in patients with liver cirrhosis
    Cezary Chojnacki
    Department of Gastroenterology, Medical University of Lodz, Łódź, Poland
    Pol Arch Med Wewn 122:392-7. 2012
    ..Hepatic encephalopathy is one of the symptoms of liver failure. The exact causes of encephalopathy are complex and still unclear. Apart from elevated blood ammonia levels, the role of numerous other factors is being considered...
  23. pmc Melatonin levels in serum and ascitic fluid of patients with hepatic encephalopathy
    Cezary Chojnacki
    Department of Gastroenterology, Medical University of Lodz, 1 Haller s Square, 90 647 Lodz, Poland
    Gastroenterol Res Pract 2012:510764. 2012
    ..Conclusions. Our results suggest that high blood levels of melatonin in cirrhotic liver patients may account for some of the clinical manifestations of hepatic encephalopathy, for example, daytime sleepiness, fatigue...
  24. doi request reprint SSTR1 and SSTR5 subtypes are the dominant forms of somatostatin receptor in neuroendocrine tumors
    Hanna Pisarek
    Department of Neuroendocrinology, Medical University of Łódź, Poland
    Folia Histochem Cytobiol 48:142-7. 2010
    ..The observed pattern suggests that apart from octreotide and lanreotide, newly synthesized multiligand analogs such as SOM 230, KE 108 or SSTR 1 and SSTR 5 selective analogs could be effective in NETs treatment...
  25. ncbi request reprint Oncostatic action of melatonin: facts and question marks
    Marek Pawlikowski
    Department of Experimental Endocrinology and Hormone Diagnostics, Institute of Endocrinology, Medical University of Lodz, Sterling str 3, 91 425 Lodz, Poland
    Neuro Endocrinol Lett 23:24-9. 2002
    ..However, the recent data from our and other laboratories suggest also the involvement of RZR/ROR receptors (the putative melatonin nuclear receptors) in both melatonin-induced proliferation inhibition and apoptosis...
  26. doi request reprint Immunohistochemical detection of angiotensin receptors AT1 and AT2 in adrenal tumors
    Marek Pawlikowski
    Department of Neuroendocrinology, Chair of Endocrinology, Medical University of Łódź, Poland pl
    Folia Histochem Cytobiol 46:51-5. 2008
    ..Our data indicates that the expression of AT1 receptors is altered in adrenal cancer and in pheochromocytomas. The expression of AT2 receptors, in turn, may be connected with the process of tumoral neo-angiogenesis...
  27. ncbi request reprint Immunohistochemical detection of follicle stimulating hormone receptor (FSHR) in neuroendocrine tumours
    Marek Pawlikowski
    Department of Immunoendocrinology, Chair of Endocrinology, Medical University of Lodz, Poland
    Endokrynol Pol 64:268-71. 2013
    ..The presentpaper reports on the incidence of FSHR in both tumoral cells and some intratumoral blood vessels of neuroendocrine tumours (NETs)...