Rita Barros

Summary

Affiliation: Institute of Molecular Pathology and Immunology
Country: Portugal

Publications

  1. doi request reprint Relevance of high virulence Helicobacter pylori strains and futility of CDX2 expression for predicting intestinal metaplasia after eradication of infection
    Rita Barros
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
    Scand J Gastroenterol 45:828-34. 2010
  2. doi request reprint Gastric intestinal metaplasia revisited: function and regulation of CDX2
    Rita Barros
    IPATIMUP Institute of Molecular Pathology and Immunology, University of Porto, 4200 465 Porto, Portugal
    Trends Mol Med 18:555-63. 2012
  3. ncbi request reprint Determinants of gastric CDX2 expression: a study in Mozambique
    Barbara Peleteiro
    Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto, Porto, Portugal
    Eur J Cancer Prev 21:532-40. 2012
  4. doi request reprint Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells
    Vânia Camilo
    Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal
    Carcinogenesis 33:1985-92. 2012
  5. doi request reprint Association between environmental factors and CDX2 expression in gastric cancer patients
    Barbara Peleteiro
    Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal
    Eur J Cancer Prev 21:423-31. 2012
  6. pmc CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype
    Rita Barros
    IPATIMUP, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    Gut 60:290-8. 2011
  7. pmc Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis
    Joana T de Oliveira
    Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Institute of Molecular Pathology and Immunology IPATIMUP, University of Porto, Porto, Portugal Instituto de Ciências Biomédicas de Abel Salazar ICBAS, University of Porto, Porto, Portugal Faculty of Veterinary Medicine of the Lusophone University of Humanities and Technologies, Lisbon, Portugal
    PLoS ONE 10:e0134458. 2015
  8. pmc Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome
    Vânia Camilo
    Institute of Molecular Pathology and Immunology of the University of Porto IPATIMUP, Rua Dr, Roberto Frias s n, 4200 465 Porto, Portugal
    BMC Cancer 14:753. 2014
  9. doi request reprint Differentiation reprogramming in gastric intestinal metaplasia and dysplasia: role of SOX2 and CDX2
    Vânia Camilo
    Institute of Molecular Pathology and Immunology of the University of Porto IPATIMUP, Porto, Portugal
    Histopathology 66:343-50. 2015
  10. pmc CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness
    Bruno Pereira
    IPATIMUP Institute of Molecular Pathology and Immunology of the University of Porto, 4200 465 Porto, Portugal
    Nucleic Acids Res 41:3986-99. 2013

Collaborators

  • Raquel Almeida
  • Barbara Peleteiro
  • Gerard R Rutteman
  • Patrícia Mesquita
  • Carla Oliveira
  • Michelina Plateroti
  • Marc Billaud
  • Carla Carrilho
  • Fatima Carneiro
  • Ceu Figueiredo
  • Joana T de Oliveira
  • Vânia Camilo
  • Leonor David
  • Claudia Ribeiro
  • Fatima Gartner
  • Augusto J de Matos
  • Rita Pinto
  • Celso A Reis
  • Catarina Gomes
  • Joana Bastos
  • Bruno Pereira
  • Sofia Sousa
  • Ana L Santos
  • Luís T da Costa
  • Pedro Valente
  • Paula Chaves
  • Maria Jose Oliveira
  • Isabel Pereira-Castro
  • Eric P Bennett
  • Sara Ricardo
  • M Helena Vasconcelos
  • Mónica Garrido
  • Ana Luísa Amaral
  • Nuno Mendes
  • João Pinto-de-Sousa
  • Joana Vieira
  • Venceslau Hespanhol
  • Manuel R Teixeira
  • Asaf Chen
  • Patricia Castro
  • Ricardo Celestino
  • Laura Carreto
  • Patricia Oliveira
  • Sandra Carvalho
  • Jean Noel Freund
  • João T Guimarães
  • Ana Marinho
  • Nicolas T Chartier
  • Maria de Fátima Pina
  • Henrique Barros
  • Hugo Pinto
  • Jean Pierre Rouault
  • Luis Alves
  • Milton Severo
  • Nuno Lunet
  • Carlo La Vecchia
  • Ana Azevedo
  • Ana Maria Magalhães
  • Teresa Lopes
  • António Mário Santos
  • Teresa Pereira

Detail Information

Publications17

  1. doi request reprint Relevance of high virulence Helicobacter pylori strains and futility of CDX2 expression for predicting intestinal metaplasia after eradication of infection
    Rita Barros
    Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal
    Scand J Gastroenterol 45:828-34. 2010
    ..pylori eradication, bringing into play the effect of the virulence of infecting H. pylori strains and the hypothesis that CDX2 expression might be a marker for later development of IM...
  2. doi request reprint Gastric intestinal metaplasia revisited: function and regulation of CDX2
    Rita Barros
    IPATIMUP Institute of Molecular Pathology and Immunology, University of Porto, 4200 465 Porto, Portugal
    Trends Mol Med 18:555-63. 2012
    ..Here, we review the pathophysiology of intestinal metaplasia in the context of the molecular network involved in its establishment and maintenance, with emphasis on CDX2 function and regulation...
  3. ncbi request reprint Determinants of gastric CDX2 expression: a study in Mozambique
    Barbara Peleteiro
    Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto, Porto, Portugal
    Eur J Cancer Prev 21:532-40. 2012
    ..64, 95% CI: 1.02-12.95). The virulence of the infecting strains and vegetable consumption were associated with CDX2 expression and may play a role in the progression to more advanced lesions...
  4. doi request reprint Helicobacter pylori and the BMP pathway regulate CDX2 and SOX2 expression in gastric cells
    Vânia Camilo
    Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal
    Carcinogenesis 33:1985-92. 2012
    ..These results provide a novel link between H. pylori infection and the BMP pathway in the regulation of intestinal and gastric-specific genes that might be relevant for gastric IM...
  5. doi request reprint Association between environmental factors and CDX2 expression in gastric cancer patients
    Barbara Peleteiro
    Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal
    Eur J Cancer Prev 21:423-31. 2012
    ....
  6. pmc CDX2 autoregulation in human intestinal metaplasia of the stomach: impact on the stability of the phenotype
    Rita Barros
    IPATIMUP, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    Gut 60:290-8. 2011
    ..This putative haplo-insufficiency, together with the apparent stability of IM, led to the hypothesis that CDX2 regulates its own expression through an autoregulatory loop in both contexts...
  7. pmc Hypoxia Up-Regulates Galectin-3 in Mammary Tumor Progression and Metastasis
    Joana T de Oliveira
    Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Institute of Molecular Pathology and Immunology IPATIMUP, University of Porto, Porto, Portugal Instituto de Ciências Biomédicas de Abel Salazar ICBAS, University of Porto, Porto, Portugal Faculty of Veterinary Medicine of the Lusophone University of Humanities and Technologies, Lisbon, Portugal
    PLoS ONE 10:e0134458. 2015
    ..In in vivo studies, galectin-3 was overexpressed in hypoxic areas of primary tumors and well-established metastases. Tumor hypoxia thus up-regulates the expression of galectin-3, which may in turn increase tumor aggressiveness. ..
  8. pmc Immunohistochemical molecular phenotypes of gastric cancer based on SOX2 and CDX2 predict patient outcome
    Vânia Camilo
    Institute of Molecular Pathology and Immunology of the University of Porto IPATIMUP, Rua Dr, Roberto Frias s n, 4200 465 Porto, Portugal
    BMC Cancer 14:753. 2014
    ..Here, we used a retrospective, observational study to assess the expression and prognostic value of the transcription factors SOX2 and CDX2 in gastric cancer...
  9. doi request reprint Differentiation reprogramming in gastric intestinal metaplasia and dysplasia: role of SOX2 and CDX2
    Vânia Camilo
    Institute of Molecular Pathology and Immunology of the University of Porto IPATIMUP, Porto, Portugal
    Histopathology 66:343-50. 2015
    ..The aim of this study was to attempt to establish the relationship of SOX2 with CDX2 and with the differentiation reprogramming that characterizes gastric carcinogenesis, to assess their involvement in IM and dysplasia...
  10. pmc CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness
    Bruno Pereira
    IPATIMUP Institute of Molecular Pathology and Immunology of the University of Porto, 4200 465 Porto, Portugal
    Nucleic Acids Res 41:3986-99. 2013
    ....
  11. doi request reprint Factors contributing to the underestimation of Helicobacter pylori-associated gastric cancer risk in a high-prevalence population
    Barbara Peleteiro
    Department of Hygiene and Epidemiology, University of Porto Medical School, Porto, Portugal
    Cancer Causes Control 21:1257-64. 2010
    ..This study aimed to identify sources of underestimation of the association between Helicobacter pylori infection and non-cardia gastric cancer, in a high-risk European population...
  12. doi request reprint Is cardia cancer aetiologically different from distal stomach cancer?
    Barbara Peleteiro
    Department of Hygiene and Epidemiology, Medical Faculty, University of Porto, Porto, Portugal
    Eur J Cancer Prev 20:96-101. 2011
    ..pylori infection in this European high-risk setting...
  13. doi request reprint Pathophysiology of intestinal metaplasia of the stomach: emphasis on CDX2 regulation
    Rita Barros
    Institute of Molecular Pathology and Immunology of the University of Porto IPATIMUP, Rua Dr Roberto Frias s n, 4200 465 Porto, Portugal
    Biochem Soc Trans 38:358-63. 2010
    ..In the present paper, we review the basic pathology of gastric IM as well as the current knowledge on molecular pathways involved in CDX2 regulation in the gastric context...
  14. pmc Anti-influenza neuraminidase inhibitor oseltamivir phosphate induces canine mammary cancer cell aggressiveness
    Joana T de Oliveira
    Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal Institute of Molecular Pathology and Immunology IPATIMUP, University of Porto, Porto, Portugal Instituto de Ciências Biomédicas de Abel Salazar ICBAS, University of Porto, Porto, Portugal Faculty of Veterinary Medicine, Lusophone University of Humanities and Technologies, Lisbon, Portugal
    PLoS ONE 10:e0121590. 2015
    ....
  15. doi request reprint Sociodemographic determinants of prevalence and incidence of Helicobacter pylori infection in Portuguese adults
    Joana Bastos
    Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal Institute of Public Health of the University of Porto ISPUP, Porto, Portugal
    Helicobacter 18:413-22. 2013
    ..pylori-related diseases. We aimed to estimate the prevalence and incidence of H. pylori infection and to identify its major sociodemographic correlates in an urban population from the North of Portugal...
  16. doi request reprint CDX2 homeoprotein is involved in the regulation of ST6GalNAc-I gene in intestinal metaplasia
    Rita Pinto
    1 Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal 2 Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal 3 Faculty of Medicine, University of Porto, Porto, Portugal
    Lab Invest 95:718-27. 2015
    ..In conclusion, we show that CDX2 transcriptionally regulates ST6GalNAc-I gene expression, specifically in the preneoplastic IM lesion. ..
  17. ncbi request reprint Differential expression of galectin-1 and galectin-3 in canine non-malignant and malignant mammary tissues and in progression to metastases in mammary tumors
    Joana T de Oliveira
    Institute of Molecular Pathology and Immunology of the, University of Porto, Porto, Portugal and Abel Salazar Institute of Biomedical Sciences, University of Porto, Porto, Portugal
    Anticancer Res 34:2211-21. 2014
    ..The aim of the present study was to investigate the expression pattern of both these galectins in canine non-neoplastic mammary tissues and mammary tumors (CMT)...