Lali Shanshiashvili

Summary

Affiliation: Ilia State University
Location: Tbilisi, Georgia
Grants:
1. 1998–2005 Co-investigator in the Georgian Academy of Sciences N1510 grant.
2. 1999–2002 Co-investigator in INTAS-Georgia 97-1561 grant.
3. 2002-2004 Co-investigator in ISTC G- 617 grant.
4. 2002-2004 Co-investigator in ISTC G- 564 grant
5. 2002-2006 Co-investigator in INTAS 2001-0666 grant.
6. 2009-2011 Co-investigator in GNSF grant N376.
7. 2010-2011 Co-investigator in STCU grant N 5048

Publications:
1.Adhesive Properties and Inflammatory Potential of Citrullinated Myelin Basic Protein Peptide 45-89. 2012 L.V.Shanshiashvili, Kalandadze IV, Ramsden JJ, Mikeladze DG. Neurochem Res.37(9):1959-66.
2.mGluR1 interacts with cystic fibrosis transmembrane conductance regulator and modulates the secretion of IL-10 in cystic fibrosis peripheral lymphocytes. 2012. L.V. Shanshiashvili, N. Dabrundashvili, N. Natsvlishvili, E. Kvaratskhelia, E. Zhuravliova, T. Barbakadze, S. Koriauli, E. Maisuradze, T. Topuria, D.G. Mikeladze Mol Immunol. Jul;51(3-4):310-5. ELSEVIER
3. Synaptic and Non-Synaptic Mitochondria in Hippocampus of Adult Rats Differ in Their Sensitivity to Hypothyroidism. 2012. Zhuravliova E, Barbakadze T, Jojua N, Zaalishvili E, Shanshiashvili L, Natsvlishvili N, Kalandadze I, Narmania N, Chogovadze I, Mikeladze D.Cell Mol Neurobiol. Jun 17. [Epub ahead of print] DOI 10.1007/s10571-012-9857-8. Springer
4.S-Nitrosylation Decreases the Adsorption of H-Ras in Lipid Bilayer and Changes Intrinsic Catalytic Activity. 2011. Shanshiashvili L, Narmania N, Barbakadze T, Zhuravliova E, Natsvlishvili N, Ramsden J, Mikeladze DG.Cell Biochem Biophys. 59, 191-199
Springer
5.Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes 2003.Shanshiashvili L., Suknidze N., Machaidze G., Mikeladze D., Ramsden J.Archives of Biochemistry and Biophysics. 419, 170-177 , Elsevier

Publications

  1. ncbi request reprint Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes
    L V Shanshiashvili
    I S Beritashvili Institute of Physiology, Georgian Academy of Sciences, Tbilisi, Georgia
    Arch Biochem Biophys 419:170-7. 2003
  2. doi request reprint Erratum to: Metabotropic glutamate receptor 5 may be involved in macrophage plasticity.
    Lali Shanshiashvili
    Ilia State University, Tbilisi, Georgia
    Biol Res 50:13. 2017
  3. doi request reprint Metabotropic glutamate receptor 5 may be involved in macrophage plasticity.
    Lali Shanshiashvili
    Ilia State University, Tbilisi, Georgia
    Biol Res 50:4. 2017
  4. doi request reprint Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89
    Lali V Shanshiashvili
    Ilia State University, 3 5 Cholokhashvili Str, 0162 Tbilisi, Georgia
    Neurochem Res 37:1959-66. 2012

Detail Information

Publications4

  1. ncbi request reprint Adhesion and clustering of charge isomers of myelin basic protein at model myelin membranes
    L V Shanshiashvili
    I S Beritashvili Institute of Physiology, Georgian Academy of Sciences, Tbilisi, Georgia
    Arch Biochem Biophys 419:170-7. 2003
    ..Implications of these results for neurological disorders involving demyelination, such as multiple sclerosis, are discussed...
  2. doi request reprint Erratum to: Metabotropic glutamate receptor 5 may be involved in macrophage plasticity.
    Lali Shanshiashvili
    Ilia State University, Tbilisi, Georgia
    Biol Res 50:13. 2017
  3. doi request reprint Metabotropic glutamate receptor 5 may be involved in macrophage plasticity.
    Lali Shanshiashvili
    Ilia State University, Tbilisi, Georgia
    Biol Res 50:4. 2017
    ..We propose that elevation of intracellular glutamate and expression of mGluR5 may initiate the metabolic rearrangement in macrophages that could contribute to the formation of an immunosuppressive phenotype...
  4. doi request reprint Adhesive properties and inflammatory potential of citrullinated myelin basic protein peptide 45-89
    Lali V Shanshiashvili
    Ilia State University, 3 5 Cholokhashvili Str, 0162 Tbilisi, Georgia
    Neurochem Res 37:1959-66. 2012
    ..Our results suggest that some citrullinated peptides, initially released from oligodendrocytes, might activate microglia, which produces reactive nitrogen species and generates in turn fatal feedbacks that kill oligodendrocytes...