Shunsuke Chiba

Summary

Affiliation: Nanyang Technological University
Country: Singapore

Publications

  1. doi request reprint Mn(III)-catalyzed synthesis of pyrroles from vinyl azides and 1,3-dicarbonyl compounds
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 10:5019-22. 2008
  2. doi request reprint A Pd(II)-catalyzed ring-expansion reaction of cyclic 2-azidoalcohol derivatives: synthesis of azaheterocycles
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 131:12886-7. 2009
  3. doi request reprint anti-Selective aminofluorination of alkenes with amidines mediated by hypervalent iodine(iii) reagents
    Hui Chen
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 14:5481-5. 2016
  4. doi request reprint Copper-catalyzed oxidative carbon-heteroatom bond formation: a recent update
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Chem Soc Rev 45:4504-23. 2016
  5. doi request reprint Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains
    Shinya Ariyasu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore
    Chem Commun (Camb) 52:4667-70. 2016
  6. doi request reprint Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Chem Commun (Camb) 52:2473-6. 2016
  7. doi request reprint TEMPO-mediated allylic C-H amination with hydrazones
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 12:4567-70. 2014
  8. doi request reprint sp3 C-H oxidation by remote H-radical shift with oxygen- and nitrogen-radicals: a recent update
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 12:4051-60. 2014
  9. pmc Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cells
    P Zhu
    School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
    Cell Death Dis 4:e552. 2013
  10. doi request reprint Copper-catalyzed redox-neutral C-H amination with amidoximes
    Hui Chen
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 12:42-6. 2014

Collaborators

  • Hajime Hirao
  • Bengang Xing
  • Jian Zhang
  • Ming Hu
  • Yu Liu
  • Teck Peng Loh
  • R Wang
  • Rui Chen
  • Lutz Ackermann
  • Yi Feng Wang
  • Xu Zhu
  • Pei Chui Too
  • Hui Chen
  • Feng Lian Zhang
  • Ya Lin Tnay
  • Kah Kah Toh
  • Atsushi Kaga
  • Line Zhang
  • Stephen Sanjaya
  • Derek Yiren Ong
  • Xingao Peng
  • Geoffroy Hervé Lonca
  • Benny Meng Kiat Tong
  • Shinya Ariyasu
  • Zonghan Hong
  • Guo Hao Chan
  • John Mondal
  • Anup Biswas
  • P Zhu
  • Tingchao He
  • Sin Yee Chong
  • Eileen Pei Jian Ng
  • Gim Yean Ang
  • Kai Xu
  • Ciputra Tejo
  • Lai Guan Ng
  • Yusuke Nishiyama
  • Yichen Ding
  • Hirohito Hayashi
  • Subas Kumar Muduli
  • Chi Ching Goh
  • Han Sen Soo
  • Edwin Kok Lee Yeow
  • Liang Yang
  • Jing Mu
  • Yanli Zhao
  • Maïwenn Le Runigo
  • Yun Yun Tan
  • G Y Ang
  • B M K Tong
  • N S Tan
  • H C Chong
  • X L Wang
  • S Foo
  • Wei Ren
  • J P Chen
  • Sophian Sahnoun
  • Yi Yuan Chua
  • Yi Li Heng
  • Handong Sun
  • Cheng Chen
  • Sze Hui Chua
  • Siong Heng Wong
  • Koichi Narasaka

Detail Information

Publications52

  1. doi request reprint Mn(III)-catalyzed synthesis of pyrroles from vinyl azides and 1,3-dicarbonyl compounds
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 10:5019-22. 2008
    ..Polysubstituted N-H pyrroles with a wide variety of substituents were prepared from vinyl azides and 1,3-dicarbonyl compounds by using Mn(III) complexes as catalysts...
  2. doi request reprint A Pd(II)-catalyzed ring-expansion reaction of cyclic 2-azidoalcohol derivatives: synthesis of azaheterocycles
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 131:12886-7. 2009
    ..A Pd(II)-catalyzed ring expansion-reaction of cyclic 2-azidoalcohol derivatives was found to proceed via an unprecedented C-C bond cleavage-C-N bond formation sequence, providing substituted azaheterocycles...
  3. doi request reprint anti-Selective aminofluorination of alkenes with amidines mediated by hypervalent iodine(iii) reagents
    Hui Chen
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 14:5481-5. 2016
    ..Further reductive ring-opening of the 2-imidazoline moiety could deliver highly functionalized 3-fluoropropane-1,2-diamine derivatives. ..
  4. doi request reprint Copper-catalyzed oxidative carbon-heteroatom bond formation: a recent update
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Chem Soc Rev 45:4504-23. 2016
    ..This review updates recent advances in Cu-catalyzed (anaerobic) oxidative carbon-heteroatom bond formation on sp(3)- and sp(2)-C-H bonds as well as alkenes, classified according to the types of stoichiometric oxidants. ..
  5. doi request reprint Glycopeptide antibiotic analogs for selective inactivation and two-photon imaging of vancomycin-resistant strains
    Shinya Ariyasu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore
    Chem Commun (Camb) 52:4667-70. 2016
    ..Moreover, this theranostic analog can be also applied for selective two-photon fluorescence imaging of Gram (+) bacteria. ..
  6. doi request reprint Construction of 1-pyrroline skeletons by Lewis acid-mediated conjugate addition of vinyl azides
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Chem Commun (Camb) 52:2473-6. 2016
    ..The reactions of vinyl azides with 3-alkylidene-2-oxoindolines afford 3',4'-dihydrospiro[indoline-3,2'-pyrrol]-2-ones in a diastereoselective fashion, whereas those with dimethyl 2-alkylidenemalonates provide 4,5-dihydro-3H-pyrroles. ..
  7. doi request reprint TEMPO-mediated allylic C-H amination with hydrazones
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 12:4567-70. 2014
    ..The transformation is featured by a sequence of remote allylic H-radical shift and allylic homolytic substitution with hydrazone radicals. ..
  8. doi request reprint sp3 C-H oxidation by remote H-radical shift with oxygen- and nitrogen-radicals: a recent update
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 12:4051-60. 2014
    ..This review updates on recent advances in aliphatic sp(3) C-H bond oxidation by remote H-radical abstraction with oxygen- and nitrogen-radicals classifying by the type of the radical precursors. ..
  9. pmc Nox4-dependent ROS modulation by amino endoperoxides to induce apoptosis in cancer cells
    P Zhu
    School of Biological Sciences, Nanyang Technological University, Singapore, Singapore
    Cell Death Dis 4:e552. 2013
    ..Altogether, our study suggests that anticancer strategies that focus on redox-based apoptosis induction in tumors are clinically viable...
  10. doi request reprint Copper-catalyzed redox-neutral C-H amination with amidoximes
    Hui Chen
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 12:42-6. 2014
    ..The reaction mechanisms could be characterized as a redox-neutral radical pathway including a Cu(I)-Cu(II) redox catalytic cycle...
  11. doi request reprint Mn(III)-catalyzed radical reactions of 1,3-dicarbonyl compounds and cyclopropanols with vinyl azides for divergent synthesis of azaheterocycles
    Shunsuke Chiba
    Nanyang Technological University, School of Physical and Mathematical Sciences, Division of Chemistry and Biological Chemistry, 21 Nanyang Link, Singapore 637371, Singapore
    Chimia (Aarau) 66:377-81. 2012
    ..Vinyl azides were successfully applied as a three-atom unit including one nitrogen to prepare various azaheterocycles via Mn(III)-catalyzed radical reactions...
  12. ncbi request reprint Synthesis of polysubstituted N-H pyrroles from vinyl azides and 1,3-dicarbonyl compounds
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 10:313-6. 2008
    ..By applying these two methods, regioisomeric pyrroles can be prepared selectively starting from the same vinyl azides...
  13. doi request reprint Generation of iminyl copper species from alpha-azido carbonyl compounds and their catalytic C-C bond cleavage under an oxygen atmosphere
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 12:2052-5. 2010
    ....
  14. doi request reprint Palladium-catalyzed dehydrogenative direct arylations of 1,2,3-triazoles
    Lutz Ackermann
    Institut fuer Organische und Biomolekulare Chemie, Georg August Universitaet, Tammannstrasse 2, 37077 Goettingen, Germany
    Org Lett 12:2056-9. 2010
    ....
  15. doi request reprint Copper-catalyzed synthesis of azaspirocyclohexadienones from alpha-azido-N-arylamides under an oxygen atmosphere
    Shunsuke Chiba
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 132:7266-7. 2010
    ..The preliminary investigation revealed that molecular oxygen is a prerequisite for achieving the present catalytic cyclization and that one of the oxygen atoms of O(2) was found to be incorporated into the cyclohexadienone moiety...
  16. doi request reprint Copper-catalyzed aerobic spirocyclization of biaryl-N-H-imines via 1,4-aminooxygenation of benzene rings
    Ya Lin Tnay
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 14:3550-3. 2012
    ..A synthetic method of azaspirocyclohexadienones has been developed through copper-catalyzed aerobic spirocyclization of biaryl-N-H-imines prepared by the reaction of biarylcarbonitriles and Grignard reagents...
  17. doi request reprint Copper-catalyzed aliphatic C-H amination with an amidine moiety
    Hui Chen
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 15:212-5. 2013
    ..The resulting products, dihydroimidazoles and tetrahydropyrimidines, could be converted into the corresponding diamines by hydride reduction...
  18. doi request reprint Copper-mediated aerobic synthesis of 3-azabicyclo[3.1.0]hex-2-enes and 4-carbonylpyrroles from N-allyl/propargyl enamine carboxylates
    Kah Kah Toh
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, Singapore
    J Am Chem Soc 133:13942-5. 2011
    ..These methodologies take advantage of orthogonal modes of chemical reactivity of readily available N-allyl/propargyl enamine carboxylates; the complementary pathways can be accessed by slight modification of the reaction conditions...
  19. doi request reprint Orthogonal aerobic conversion of N-benzyl amidoximes to 1,2,4-oxadiazoles or quinazolinones
    Feng Lian Zhang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Biomol Chem 11:6003-7. 2013
    ..This orthogonal product selectivity could be realized by difference of the reaction temperature as well as selection of the solvents and inorganic bases. ..
  20. doi request reprint Copper-catalyzed aerobic intramolecular carbo- and amino-oxygenation of alkynes for synthesis of azaheterocycles
    Kah Kah Toh
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 14:2290-2. 2012
    ..This strategy was further applied for N-alkynylamidines for amino-oxygenation of alkynes, leading to imidazole and quinazoline derivatives...
  21. doi request reprint Copper-catalyzed aerobic [3+2]-annulation of N-alkenyl amidines
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 134:3679-82. 2012
    ..These cyclic amidines could be converted into mono-benzyl-protected vicinal diamines by the reduction with aluminum hydride...
  22. doi request reprint Formal [4 + 1]- and [5 + 1]-annulation by an S(N)2-conjugate addition sequence: stereoselective synthesis of highly substituted carbocycles
    Benny Meng Kiat Tong
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 14:2826-9. 2012
    ....
  23. doi request reprint Mn(III)-mediated formal [3+3]-annulation of vinyl azides and cyclopropanols: a divergent synthesis of azaheterocycles
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 133:6411-21. 2011
    ..In addition, application of the present methodology to a synthesis of the quaternary indole alkaloid, melinonine-E, was accomplished...
  24. doi request reprint Synthesis of azaheterocycles from aryl ketone O-acetyl oximes and internal alkynes by Cu-Rh bimetallic relay catalysts
    Pei Chui Too
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Org Chem 76:6159-68. 2011
    ..The Cu-Rh bimetallic system could be applied for the synthesis of isoquinolines as well as β-carboline, furo[2.3-c]pyridine, pyrrolo[2,3-c]pyridine, and thieno[2,3-c]pyridine derivatives...
  25. doi request reprint Copper-catalyzed synthesis of phenanthridine derivatives under an oxygen atmosphere starting from biaryl-2-carbonitriles and Grignard reagents
    Line Zhang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 12:3682-5. 2010
    ....
  26. doi request reprint Understanding the Origins of Nucleophilic Hydride Reactivity of a Sodium Hydride-Iodide Composite
    Zonghan Hong
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371, Singapore
    Chemistry 22:7108-14. 2016
    ....
  27. doi request reprint Chemical conversion of β-O-4 lignin linkage models through Cu-catalyzed aerobic amide bond formation
    Jian Zhang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637616
    Chem Commun (Camb) 49:11439-41. 2013
    ....
  28. doi request reprint Amide synthesis by nucleophilic attack of vinyl azides
    Feng Lian Zhang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Singapore
    Angew Chem Int Ed Engl 53:4390-4. 2014
    ..After nucleophilic attack of the vinyl azide, a substituent of the resulting iminodiazonium ion intermediate migrates to form a nitrilium ion, which is hydrolyzed to afford the corresponding amide. ..
  29. doi request reprint A CuBr-mediated aerobic reaction of 2-alkynylbenzaldehydes and primary amines: synthesis of 4-bromoisoquinolones
    Pei Chui Too
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Chem Commun (Camb) 48:7634-6. 2012
    ..A method for synthesis of 4-bromoisoquinolones has been developed starting from 2-alkynylbenzaldehydes and primary amines mediated by CuBr under an O(2) atmosphere, where CuBr plays multiple roles to facilitate the present reactions...
  30. doi request reprint Mn(III)-mediated reactions of cyclopropanols with vinyl azides: synthesis of pyridine and 2-azabicyclo[3.3.1]non-2-en-1-ol derivatives
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 131:12570-2. 2009
    ..In addition, versatile transformations of 2-azabicyclo[3.3.1]non-2-en-1-ol to 2-azabicyclo[3.3.1]nonane or -non-2-nen frameworks were developed...
  31. pmc Hydride Reduction by a Sodium Hydride-Iodide Composite
    Pei Chui Too
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore
    Angew Chem Int Ed Engl 55:3719-23. 2016
    ..This remarkably simple protocol endows NaH with unprecedented and unique hydride-donor chemical reactivity. ..
  32. doi request reprint Diastereo-Divergent Synthesis of Saturated Azaheterocycles Enabled by tBuOK-Mediated Hydroamination of Alkenyl Hydrazones
    Atsushi Kaga
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Singapore
    Chemistry 21:19112-8. 2015
    ..By contrast, 2,5-trans selectivity was observed when an isopropyl group was used as the substituent on hydrazones. An unusual 2,6-trans selectivity in piperidine formation was also realized using the present strategy. ..
  33. doi request reprint Formal [4+2]-annulation of vinyl azides with N-unsaturated aldimines
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Singapore, Fax 65 6791 1961
    Chem Asian J 9:2458-62. 2014
    ....
  34. doi request reprint Oxidative radical skeletal rearrangement induced by molecular oxygen: synthesis of quinazolinones
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 15:2842-5. 2013
    ..Concise syntheses of biologically active quinazolinone derivatives were demonstrated using the present strategy...
  35. doi request reprint TEMPO-mediated aliphatic C-H oxidation with oximes and hydrazones
    Xu Zhu
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 15:3214-7. 2013
    ..A method for aliphatic C-H bond oxidation of oximes and hydrazones mediated by 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) has been developed, which enables the concise assembly of substituted isoxazole and pyrazole skeletons. ..
  36. ncbi request reprint Copper-catalyzed aerobic aliphatic C-H oxygenation directed by an amidine moiety
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 134:11980-3. 2012
    ..The oxygen atom is incorporated from atmospheric molecular oxygen during the present process...
  37. doi request reprint Diastereoselective aminooxygenation and diamination of alkenes with amidines by hypervalent iodine(III) reagents
    Hui Chen
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 16:6136-9. 2014
    ..The present transformation offers diastereochemically pure dihydroimidazoles divergently from E- and Z-alkenes. ..
  38. doi request reprint Synthesis of Fasicularin
    Atsushi Kaga
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 18:3506-8. 2016
    ..Stereoselective synthesis of the aza-spirocyclic BC-ring precursor and ensuing construction of the A-ring with stereocontrolled installation of the C2 hexyl group feature prominently in the synthesis. ..
  39. ncbi request reprint Rhodium(III)-Catalyzed Synthesis of Isoquinolines from Aryl Ketone O-Acyloxime Derivatives and Internal Alkynes
    Pei Chui Too
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 12:5688-91. 2010
    ....
  40. doi request reprint Tf2NH-Catalyzed Amide Synthesis from Vinyl Azides and Alcohols
    Feng Lian Zhang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 17:3138-41. 2015
    ....
  41. doi request reprint Synthesis of polyfluoroalkyl aza-polycyclic aromatic hydrocarbons enabled by addition of perfluoroalkyl radicals onto vinyl azides
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 16:4272-5. 2014
    ....
  42. doi request reprint Copper-mediated oxidative transformation of N-allyl enamine carboxylates toward synthesis of azaheterocycles
    Kah Kah Toh
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    J Am Chem Soc 136:6011-20. 2014
    ..In addition, diastereoselective reduction of 3-azabicyclo[3.1.0]hex-2-enes to 3-azabicyclo[3.1.0]hexanes was achieved using NaBH3CN in the presence of acetic acid. ..
  43. ncbi request reprint Copper-catalyzed benzylic C-H oxygenation under an oxygen atmosphere via N-H imines as an intramolecular directing group
    Line Zhang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 13:1622-5. 2011
    ....
  44. doi request reprint Hydrodehalogenation of Haloarenes by a Sodium Hydride-Iodide Composite
    Derek Yiren Ong
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore, 637371, Singapore
    Angew Chem Int Ed Engl . 2017
    ..Mechanistic studies showed that an unusual concerted nucleophilic aromatic substitution operates in the present process...
  45. doi request reprint Linking of Alcohols with Vinyl Azides
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 18:992-5. 2016
    ..The as-prepared cyanine dye linked testosterones were capable of rapid cell membrane imaging in real time. ..
  46. doi request reprint Copper-catalyzed aerobic cc bond cleavage of lactols with N-hydroxy phthalimide for synthesis of lactones
    Ya Lin Tnay
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Singapore
    Chem Asian J 10:873-7. 2015
    ....
  47. pmc Cu(0) nanoparticles deposited on nanoporous polymers: a recyclable heterogeneous nanocatalyst for Ullmann coupling of aryl halides with amines in water
    John Mondal
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637371
    Sci Rep 5:8294. 2015
    ..No Cu leaching from the nanocatalyst surface and the smooth nanocatalyst recovery confirm the true heterogeneity in these catalytic reactions. ..
  48. doi request reprint Inorganic-base-mediated hydroamination of alkenyl oximes for the synthesis of cyclic nitrones
    Xingao Peng
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Singapore
    Angew Chem Int Ed Engl 53:1959-62. 2014
    ..The transition state of this reaction is stabilized by an ionic interaction between a metal cation such as K(+) and the oxime oxygen and negatively charged alkene moiety. ..
  49. doi request reprint PhI(OAc)(2) -mediated radical trifluoromethylation of vinyl azides with Me(3)SiCF(3)
    Yi Feng Wang
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371 Singapore
    Angew Chem Int Ed Engl 53:1067-71. 2014
    ..The resulting α-trifluoromethyl azines were successfully transformed to valuable fluorine-containing molecules such as α-trifluoromethyl ketones, β-trifluoromethyl amines, 5-fluoropyrazoles, and trifluoroethyl isoquinolines. ..
  50. doi request reprint Copper-Catalyzed Aminooxygenation of N-Allylamidines with PhI(OAc)(2)
    Stephen Sanjaya
    Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Org Lett 14:5342-5. 2012
    ....
  51. doi request reprint Concise synthesis and two-photon-excited deep-blue emission of 1,8-diazapyrenes
    Tingchao He
    Division of Physics and Applied Physics, School of Physical and Mathematical Sciences, Nanyang Technological University, Singapore 637371, Singapore
    Chem Asian J 7:2090-5. 2012
    ..These experimental results are explained in terms of the effects of extension of the π-conjugated system, intramolecular charge transfer, and reduced detuning energy...
  52. ncbi request reprint Synthesis of (-)-sordarin
    Shunsuke Chiba
    Department of Chemistry, Graduate School of Science, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    J Am Chem Soc 128:6931-7. 2006
    ....