- Aznar J, Vaya A, Estelles A, Mira Y, Segui R, Villa P, et al. Risk of venous thrombosis in carriers of the prothrombin G20210A variant and factor V Leiden and their interaction with oral contraceptives. Haematologica. 2000;85:1271-6 pubmed..The use of OC by women with the prothrombin G20210A variant or FV Leiden, either alone or combined with other thrombotic risk factors, was associated with a significant increase in the risk of venous thrombosis. ..
- Aznar J, Mira Y, Vaya A, Corella D, Ferrando F, Villa P, et al. Factor V Leiden and prothrombin G20210A mutations in young adults with cryptogenic ischemic stroke. Thromb Haemost. 2004;91:1031-4 pubmed..OC use is also a significant risk factor for cryptogenic stroke, which is increased in women with some genetic thrombotic risk factor. ..