Mauricio G Mateu

Summary

Country: Spain

Publications

  1. ncbi request reprint Conformational stability of dimeric and monomeric forms of the C-terminal domain of human immunodeficiency virus-1 capsid protein
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Mol Biol 318:519-31. 2002
  2. ncbi request reprint In vitro disassembly of a parvovirus capsid and effect on capsid stability of heterologous peptide insertions in surface loops
    Aura Carreira
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 279:6517-25. 2004
  3. doi request reprint Introduction: the structural basis of virus function
    Mauricio G Mateu
    Centro de Biología Molecular Severo Ochoa CSIC UAM and Department of Molecular Biology, Universidad Autonoma de Madrid, c Nicolas Cabrera 1, Campus de Cantoblanco, 28049, Madrid, Spain
    Subcell Biochem 68:3-51. 2013
  4. doi request reprint Assembly, stability and dynamics of virus capsids
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Arch Biochem Biophys 531:65-79. 2013
  5. doi request reprint Mechanical properties of viruses analyzed by atomic force microscopy: a virological perspective
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Virus Res 168:1-22. 2012
  6. doi request reprint The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    FEBS J 276:6098-109. 2009
  7. doi request reprint Virus engineering: functionalization and stabilization
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Protein Eng Des Sel 24:53-63. 2011
  8. doi request reprint A slender tract of glycine residues is required for translocation of the VP2 protein N-terminal domain through the parvovirus MVM capsid channel to initiate infection
    Milagros Castellanos
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco 28049 Madrid, Spain
    Biochem J 455:87-94. 2013
  9. pmc Mechanical elasticity as a physical signature of conformational dynamics in a virus particle
    Milagros Castellanos
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 109:12028-33. 2012
  10. pmc Engineering viable foot-and-mouth disease viruses with increased thermostability as a step in the development of improved vaccines
    Roberto Mateo
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 82:12232-40. 2008

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Conformational stability of dimeric and monomeric forms of the C-terminal domain of human immunodeficiency virus-1 capsid protein
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Mol Biol 318:519-31. 2002
    ..It is proposed that dimerization of the C-terminal domain of the HIV-1 capsid protein involves induced-fit recognition, and the conformational reorganization also improves substantially the low intrinsic stability of each monomeric half...
  2. ncbi request reprint In vitro disassembly of a parvovirus capsid and effect on capsid stability of heterologous peptide insertions in surface loops
    Aura Carreira
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 279:6517-25. 2004
    ..The results with one of the simplest viral capsids reveal a complex pathway for disassembly, and a reduction in capsid assembly and stability upon insertion of peptides, even within the most exposed capsid loops...
  3. doi request reprint Introduction: the structural basis of virus function
    Mauricio G Mateu
    Centro de Biología Molecular Severo Ochoa CSIC UAM and Department of Molecular Biology, Universidad Autonoma de Madrid, c Nicolas Cabrera 1, Campus de Cantoblanco, 28049, Madrid, Spain
    Subcell Biochem 68:3-51. 2013
    ..This chapter is also intended as a "road map" to help interconnect and integrate in a single picture the different topics described in depth in the 21 monographic chapters in this book...
  4. doi request reprint Assembly, stability and dynamics of virus capsids
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Arch Biochem Biophys 531:65-79. 2013
    ..This article provides an updated general overview on structural, biophysical and biochemical aspects of the assembly, stability and dynamics of virus capsids...
  5. doi request reprint Mechanical properties of viruses analyzed by atomic force microscopy: a virological perspective
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Virus Res 168:1-22. 2012
    ....
  6. doi request reprint The capsid protein of human immunodeficiency virus: intersubunit interactions during virus assembly
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    FEBS J 276:6098-109. 2009
    ..Those studies are leading to a better understanding of molecular recognition events during virus morphogenesis, and are also relevant for the development of anti-HIV drugs that are able to interfere with capsid assembly or disassembly...
  7. doi request reprint Virus engineering: functionalization and stabilization
    Mauricio G Mateu
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Protein Eng Des Sel 24:53-63. 2011
    ....
  8. doi request reprint A slender tract of glycine residues is required for translocation of the VP2 protein N-terminal domain through the parvovirus MVM capsid channel to initiate infection
    Milagros Castellanos
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco 28049 Madrid, Spain
    Biochem J 455:87-94. 2013
    ..The results demonstrate the exquisite dependence on geometric constraints of a biologically relevant translocation event in a biomolecular complex. ..
  9. pmc Mechanical elasticity as a physical signature of conformational dynamics in a virus particle
    Milagros Castellanos
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 109:12028-33. 2012
    ....
  10. pmc Engineering viable foot-and-mouth disease viruses with increased thermostability as a step in the development of improved vaccines
    Roberto Mateo
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 82:12232-40. 2008
    ....
  11. pmc A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid lability and confer resistance to acid-dependent uncoating inhibition
    Miguel A Martín-Acebes
    Centro de Biologia Molecular Severo Ochoa, Cantoblanco 28049, Madrid, Spain
    J Virol 84:2902-12. 2010
    ..In addition, the increased propensity to dissociation into pentameric subunits of virions bearing substitution VP3 A118V indicates that this replacement also facilitates the dissociation of the FMDV capsid...
  12. pmc Thermodynamic stability of a cold-adapted protein, type III antifreeze protein, and energetic contribution of salt bridges
    Olga García-Arribas
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Protein Sci 16:227-38. 2007
    ..In addition, it indicates that salt bridge networks are used in nature also for the stability of psychrophilic proteins, and has led to a type III AFP variant of increased stability that could be used for biotechnological purposes...
  13. ncbi request reprint Electrostatic repulsion, compensatory mutations, and long-range non-additive effects at the dimerization interface of the HIV capsid protein
    Marta del Alamo
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Mol Biol 345:893-906. 2005
    ....
  14. pmc Systematic study of the genetic response of a variable virus to the introduction of deleterious mutations in a functional capsid region
    Eva Luna
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 83:10140-51. 2009
    ....
  15. pmc Role of interfacial amino acid residues in assembly, stability, and conformation of a spherical virus capsid
    Juan Reguera
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 101:2724-9. 2004
    ..Thus, at the subunit interfaces of this model virus capsid, only key residues involved in the strongest interactions are critical for assembly and stability, but additional residues fulfill other important biological roles...
  16. ncbi request reprint Nuclear transport of trimeric assembly intermediates exerts a morphogenetic control on the icosahedral parvovirus capsid
    Laura Riolobos
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, 28049 Cantoblanco, Madrid, Spain
    J Mol Biol 357:1026-38. 2006
    ..Therefore, the nuclear transport stoichiometry of assembly intermediates may exert a morphogenetic quality control on macromolecular complexes like the MVM capsid...
  17. pmc Mechanical disassembly of single virus particles reveals kinetic intermediates predicted by theory
    Milagros Castellanos
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Departamento de Física de la Materia Condensada C III, Universidad Autonoma de Madrid, Madrid, Spain
    Biophys J 102:2615-24. 2012
    ..We conclude that mechanical manipulation and imaging of simple virus particles by AFM can be used to experimentally identify kinetic intermediates predicted by simulations of assembly or disassembly...
  18. doi request reprint Molecular determinants of self-association and rearrangement of a trimeric intermediate during the assembly of a parvovirus capsid
    Rebeca Pérez
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Mol Biol 413:32-40. 2011
    ....
  19. pmc Effect of macromolecular crowding agents on human immunodeficiency virus type 1 capsid protein assembly in vitro
    Marta del Alamo
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, Spain
    J Virol 79:14271-81. 2005
    ....
  20. ncbi request reprint Thermodynamic dissection of a low affinity protein-protein interface involved in human immunodeficiency virus assembly
    Marta del Alamo
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 278:27923-9. 2003
    ..The results reveal differences that may have been evolutionary selected and that may be exploited for the design of an effective interfacial inhibitor of human immunodeficiency virus assembly...
  21. pmc A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid resistance
    Miguel A Martín-Acebes
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Cantoblanco 28049, Madrid, Spain
    J Virol 85:2733-40. 2011
    ..The mutants described here extend the panel of FMDV variants exhibiting different pH sensitivities and illustrate the adaptive flexibility of viral quasispecies to pH variations...
  22. ncbi request reprint Functional relevance of amino acid residues involved in interactions with ordered nucleic acid in a spherical virus
    Juan Reguera
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco 28049 Madrid, Spain
    J Biol Chem 280:17969-77. 2005
    ..Their effect appears to be mediated by the non-covalent interactions they establish with the viral DNA. In addition, at least one acidic residue at each DNA-binding region is needed for DNA packaging...
  23. pmc Effects of macromolecular crowding on the inhibition of virus assembly and virus-cell receptor recognition
    Verónica Rincón
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, Madrid, Spain
    Biophys J 100:738-46. 2011
    ..The results, discussed in the light of macromolecular crowding theory, are relevant for a quantitative understanding of molecular recognition processes during virus infection and its inhibition...
  24. pmc Association equilibrium of the HIV-1 capsid protein in a crowded medium reveals that hexamerization during capsid assembly requires a functional C-domain dimerization interface
    Rebeca Bocanegra
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Madrid, Spain
    Biophys J 104:884-93. 2013
    ....
  25. pmc Resolving structure and mechanical properties at the nanoscale of viruses with frequency modulation atomic force microscopy
    David Martínez-Martín
    Departamento Física de la Materia Condensada, Universidad Autonoma de Madrid, Madrid, Spain
    PLoS ONE 7:e30204. 2012
    ..In particular, the importance of mechanical interactions is a hot topic in different aspects of biotechnology ranging from protein folding to stem cells differentiation where conventional AFM modes are already being used...
  26. ncbi request reprint Insights into RNA virus mutant spectrum and lethal mutagenesis events: replicative interference and complementation by multiple point mutants
    Celia Perales
    Centro de Biologia Molecular, Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Mol Biol 369:985-1000. 2007
    ....
  27. ncbi request reprint Structural tolerance versus functional intolerance to mutation of hydrophobic core residues surrounding cavities in a parvovirus capsid
    Aura Carreira
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco 28049 Madrid, Spain
    J Mol Biol 360:1081-93. 2006
    ....
  28. ncbi request reprint Thermostable variants are not generally represented in foot-and-mouth disease virus quasispecies
    Roberto Mateo
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Gen Virol 88:859-64. 2007
    ..This suggests that no substantial increase in the thermostability of FMDV may readily occur without a negative effect on viral function...
  29. pmc Biophysical analysis of the MHR motif in folding and domain swapping of the HIV capsid protein C-terminal domain
    Rebeca Bocanegra
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Madrid, Spain
    Biophys J 108:338-49. 2015
    ..This energetic dissection of the dimerization interface in MHR-swapped CTD may also facilitate the design of anti-HIV compounds that inhibit capsid assembly by conformational trapping of swapped CTD dimers. ..
  30. pmc Rationally designed interfacial peptides are efficient in vitro inhibitors of HIV-1 capsid assembly with antiviral activity
    Rebeca Bocanegra
    Centro de Biologia Molecular Severo Ochoa, Consejo Superior de Investigaciones Cientificas Universidad Autonoma de Madrid, Madrid, Spain
    PLoS ONE 6:e23877. 2011
    ..This study validates a novel, entirely rational approach for the design of capsid assembly interfacial inhibitors that show antiviral activity...
  31. doi request reprint Molecular recognition in the human immunodeficiency virus capsid and antiviral design
    Rebeca Bocanegra
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    Virus Res 169:388-410. 2012
    ..As a complement, we present novel experimental results on the development and proof-of-concept application of a combinatorial approach to study molecular recognition in CA and its inhibition by peptide compounds...
  32. ncbi request reprint Imaging and Quantitation of a Succession of Transient Intermediates Reveal the Reversible Self-Assembly Pathway of a Simple Icosahedral Virus Capsid
    María Medrano
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, 28049 Madrid, Spain
    J Am Chem Soc 138:15385-15396. 2016
    ..Finally, the efficient in vitro self-assembly achieved for the oncotropic, cell nucleus-targeted MVM capsid may facilitate its development as a drug-encapsidating nanoparticle for anticancer targeted drug delivery...
  33. ncbi request reprint Phage phi29 DNA replication organizer membrane protein p16.7 contains a coiled coil and a dimeric, homeodomain-related, functional domain
    Daniel Muñoz-Espín
    Instituto de Biología Molecular Eladio Viñuela, Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma, Canto Blanco, 28049 Madrid, Spain
    J Biol Chem 279:50437-45. 2004
    ..7C is evolutionarily related to DNA binding homeodomains, present in many eukaryotic transcriptional regulator proteins. Based on the results, a structural model of p16.7 is presented...
  34. ncbi request reprint Complete alanine scanning of intersubunit interfaces in a foot-and-mouth disease virus capsid reveals critical contributions of many side chains to particle stability and viral function
    Roberto Mateo
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Biol Chem 278:41019-27. 2003
    ..iii). A few interfacial side chains are functionally tolerant to truncation and may provide adequate mutation sites for the engineering of a thermostable capsid, potentially useful as an improved vaccine...
  35. pmc Deterministic, compensatory mutational events in the capsid of foot-and-mouth disease virus in response to the introduction of mutations found in viruses from persistent infections
    Roberto Mateo
    Centro de Biologia Molecular Severo Ochoa, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 81:1879-87. 2007
    ....
  36. pmc Manipulation of the mechanical properties of a virus by protein engineering
    Carolina Carrasco
    Departamento de Física de la Materia Condensada C III and Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    Proc Natl Acad Sci U S A 105:4150-5. 2008
    ..This study also demonstrates that it is possible to control the mechanical properties of a protein nanoparticle by the rational application of protein engineering based on a mechanical model...
  37. doi request reprint Different functional sensitivity to mutation at intersubunit interfaces involved in consecutive stages of foot-and-mouth disease virus assembly
    Verónica Rincón
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Gen Virol 96:2595-606. 2015
    ....
  38. doi request reprint Identification of the structural basis of thermal lability of a virus provides a rationale for improved vaccines
    Verónica Rincón
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Madrid 28049, Spain
    Structure 22:1560-70. 2014
    ..The implications for virus biology and the design of thermostable vaccines are discussed. ..
  39. doi request reprint Quantitatively probing propensity for structural transitions in engineered virus nanoparticles by single-molecule mechanical analysis
    Milagros Castellanos
    Centro de Biologia Molecular Severo Ochoa CSIC UAM, Universidad Autonoma de Madrid, Madrid 28049, Spain
    Nanoscale 7:5654-64. 2015
    ....
  40. doi request reprint Mechanical properties of viruses
    Pedro J de Pablo
    Department of Physics of the Condensed Matter, C03, Facultad de Ciencias, Universidad Autonoma de Madrid, Campus de Cantoblanco, 28049, Madrid, Spain
    Subcell Biochem 68:519-51. 2013
    ..This chapter describes what is known on the mechanical properties of virus particles, their structural determinants, and possible biological implications, of which several examples are provided...
  41. pmc High mutant frequency in populations of a DNA virus allows evasion from antibody therapy in an immunodeficient host
    Alberto López-Bueno
    Centro de Biología Molecular Severo Ochoa Consejo Superior de Investigaciones Científicas Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain
    J Virol 77:2701-8. 2003
    ..These findings indicate a high genetic heterogeneity and rapid adaptation of populations of a mammal DNA virus in vivo and provide a genetic basis for the failure of passive immunotherapy in the natural host...
  42. pmc An extensive thermodynamic characterization of the dimerization domain of the HIV-1 capsid protein
    María C Lidón-Moya
    Instituto de Biologia Molecular y Celular, Edificio Torregaitan, Universidad Miguel Hernandez, Avda del Ferrocarril s n, 03202 Elche Alicante, Spain
    Protein Sci 14:2387-404. 2005
    ..These features are characteristic of molten globule-like conformations, and they resemble the properties of the second species observed in thermal unfolding...
  43. pmc The dimerization domain of the HIV-1 capsid protein binds a capsid protein-derived peptide: a biophysical characterization
    María T Garzón
    Instituto de Biologia Molecular y Celular, Edificio Torregaitan, Universidad Miguel Hernandez, Avda del Ferrocarril s n, 03202 Elche Alicante, Spain
    Protein Sci 13:1512-23. 2004
    ..This apparent dissociation constant was only five times higher than was the dissociation constant of both CA-C and the intact capsid protein homodimers (10 microM)...
  44. pmc Flexibility in HIV-1 assembly subunits: solution structure of the monomeric C-terminal domain of the capsid protein
    Luis A Alcaraz
    Instituto de Biologia Molecular y Celular, Universidad Miguel Hernandez, Elche Alicante, Spain
    Biophys J 93:1264-76. 2007
    ..This extraordinary ability of CAC to change its structure may contribute to the different modes of association of CA during HIV assembly, and should be taken into account in the design of new drugs against this virus...
  45. ncbi request reprint The isolated C-terminal domain of Ring1B is a dimer made of stable, well-structured monomers
    Anna Czypionka
    Instituto de Biologia Molecular y Celular, Universidad Miguel Hernandez, 03202 Elche Alicante, Spain
    Biochemistry 46:12764-76. 2007
    ..Since the C-terminal region is important for interaction with other proteins of the PRC1, the dimerization and the presence of those well-structured monomers might be a form of regulation...
  46. doi request reprint Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein
    Luis A Alcaraz
    Instituto de Biologia Molecular y Celular, Universidad Miguel Hernandez, Elche Alicante, Spain
    FEBS J 275:3299-311. 2008
    ....
  47. pmc Minute virus of mice, a parvovirus, in complex with the Fab fragment of a neutralizing monoclonal antibody
    Bärbel Kaufmann
    Department of Biological Sciences, Purdue University, 915 W State Street, West Lafayette, IN 47907 2054, USA
    J Virol 81:9851-8. 2007
    ..This finding suggests that the interaction of B7 with three symmetry-related viral subunits at each spike hinders structural transitions in the viral capsid essential during viral entry...
  48. pmc Envelope lipids regulate the in vitro assembly of the HIV-1 capsid
    Francisco N Barrera
    Biophys J 94:L8-10. 2008
    ..These results suggest that specific lipids of the viral envelope could have a regulatory role in the maturation of type 1 human immunodeficiency virus...