Eniko Sonkoly

Summary

Affiliation: Karolinska Institutet
Country: Sweden

Publications

  1. pmc Advances in microRNAs: implications for immunity and inflammatory diseases
    E Sonkoly
    Department of Medicine, Unit of Dermatology and Venerology, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    J Cell Mol Med 13:24-38. 2009
  2. doi request reprint Protein kinase C-dependent upregulation of miR-203 induces the differentiation of human keratinocytes
    Eniko Sonkoly
    Molecular Dermatology Research Group, Unit of Dermatology and Venerology, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 130:124-34. 2010
  3. doi request reprint microRNAs in inflammation
    Eniko Sonkoly
    Molecular Dermatology Research Group, Unit of Dermatology and Venerology, Department of Medicine, Karolinska Institute, Stockholm, Sweden
    Int Rev Immunol 28:535-61. 2009
  4. doi request reprint MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4
    Eniko Sonkoly
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Allergy Clin Immunol 126:581-9.e1-20. 2010
  5. doi request reprint MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2
    Ning Xu
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 131:1521-9. 2011
  6. doi request reprint MiR-146a negatively regulates TLR2-induced inflammatory responses in keratinocytes
    Florian Meisgen
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 134:1931-40. 2014
  7. doi request reprint MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40
    Ning Xu
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institute, SE 17176 Stockholm, Sweden
    J Immunol 190:678-88. 2013
  8. pmc MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?
    Eniko Sonkoly
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 2:e610. 2007
  9. pmc MicroRNA-125b down-regulates matrix metallopeptidase 13 and inhibits cutaneous squamous cell carcinoma cell proliferation, migration, and invasion
    Ning Xu
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, SE 17176 Stockholm, Sweden
    J Biol Chem 287:29899-908. 2012
  10. doi request reprint MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis
    Ankit Srivastava
    Dermatology and Venerology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Allergy Clin Immunol . 2016

Collaborators

Detail Information

Publications19

  1. pmc Advances in microRNAs: implications for immunity and inflammatory diseases
    E Sonkoly
    Department of Medicine, Unit of Dermatology and Venerology, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    J Cell Mol Med 13:24-38. 2009
    ..Here, we review what is known about the role of miRN in the pathogenesis of immune-related diseases such as chronic inflammatory skin diseases, autoimmunity and viral infections...
  2. doi request reprint Protein kinase C-dependent upregulation of miR-203 induces the differentiation of human keratinocytes
    Eniko Sonkoly
    Molecular Dermatology Research Group, Unit of Dermatology and Venerology, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 130:124-34. 2010
    ..These results suggest that upregulation of miR-203 in human keratinocytes is required for their differentiation and is dependent on the activation of the PKC/AP-1 pathway...
  3. doi request reprint microRNAs in inflammation
    Eniko Sonkoly
    Molecular Dermatology Research Group, Unit of Dermatology and Venerology, Department of Medicine, Karolinska Institute, Stockholm, Sweden
    Int Rev Immunol 28:535-61. 2009
    ..In this review, we summarize the current knowledge about miRNAs in immunity and inflammation, focusing on the recent results on miRNAs involved in the regulation of immune responses and inflammatory diseases...
  4. doi request reprint MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4
    Eniko Sonkoly
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Allergy Clin Immunol 126:581-9.e1-20. 2010
    ..MicroRNAs (miRNAs) are short noncoding RNAs that suppress gene expression at the posttranscriptional level. Atopic dermatitis is a common chronic inflammatory skin disease characterized by the presence of activated T cells within the skin...
  5. doi request reprint MiR-125b, a microRNA downregulated in psoriasis, modulates keratinocyte proliferation by targeting FGFR2
    Ning Xu
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 131:1521-9. 2011
    ..Loss of miR-125b in psoriasis skin may contribute to hyperproliferation and aberrant differentiation of keratinocytes...
  6. doi request reprint MiR-146a negatively regulates TLR2-induced inflammatory responses in keratinocytes
    Florian Meisgen
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 134:1931-40. 2014
    ....
  7. doi request reprint MicroRNA-31 is overexpressed in psoriasis and modulates inflammatory cytokine and chemokine production in keratinocytes via targeting serine/threonine kinase 40
    Ning Xu
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institute, SE 17176 Stockholm, Sweden
    J Immunol 190:678-88. 2013
    ..Our data indicate that inhibition of miR-31 may be a potential therapeutic option in psoriasis...
  8. pmc MicroRNAs: novel regulators involved in the pathogenesis of psoriasis?
    Eniko Sonkoly
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 2:e610. 2007
    ..Taken together, a new layer of regulatory mechanisms is involved in the pathogenesis of chronic inflammatory skin diseases...
  9. pmc MicroRNA-125b down-regulates matrix metallopeptidase 13 and inhibits cutaneous squamous cell carcinoma cell proliferation, migration, and invasion
    Ning Xu
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, SE 17176 Stockholm, Sweden
    J Biol Chem 287:29899-908. 2012
    ..These findings provide a novel molecular mechanism by which MMP13 is up-regulated in cSCCs and indicate that miR-125b plays a tumor suppressive role in cSCC...
  10. doi request reprint MicroRNA-146a suppresses IL-17-mediated skin inflammation and is genetically associated with psoriasis
    Ankit Srivastava
    Dermatology and Venerology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Allergy Clin Immunol . 2016
    ..Little has been known about the role of noncoding RNAs, including microRNAs (miRNAs), in predisposition to the disease...
  11. doi request reprint MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration
    Dongqing Li
    Molecular Dermatology Research Group, Unit of Dermatology and Venereology, Centre for Molecular Medicine CMM, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 135:1676-85. 2015
    ..Collectively, we identify miR-31 as a key regulator for promoting keratinocyte proliferation and migration during wound healing. ..
  12. ncbi request reprint MiR-21 is up-regulated in psoriasis and suppresses T cell apoptosis
    Florian Meisgen
    Dermatology and Venereology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden Unit of Clinical Allergy Research, Department of Medicine, Karolinska Institutet, Stockholm, Sweden Santaris Pharma A S, Hørsholm, Denmark Department of Dermatology and Allergology, University of Szeged, Szeged, Hungary Copenhagen Institute of Technology, Aalborg University, Denmark
    Exp Dermatol 21:312-4. 2012
    ..Our results suggest that miR-21 suppresses apoptosis in activated T cells, and thus, overexpression of miR-21 may contribute to T cell-derived psoriatic skin inflammation...
  13. doi request reprint MicroRNAs and immunity: novel players in the regulation of normal immune function and inflammation
    Eniko Sonkoly
    Molecular Dermatology Research Group, Unit of Dermatology and Venerology, Center for Molecular Medicine, Department of Medicine, Karolinska Institutet, SE 17176 Stockholm, Sweden
    Semin Cancer Biol 18:131-40. 2008
    ..g. miR-196). In this review, we will summarize the latest findings about the role of miRNAs in the development of the immune system and regulation of immune functions and inflammation...
  14. pmc MicroRNA-31 is overexpressed in cutaneous squamous cell carcinoma and regulates cell motility and colony formation ability of tumor cells
    Aoxue Wang
    Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    PLoS ONE 9:e103206. 2014
    ..These results indicate that miR-31 regulates cancer-associated phenotypes of cSCC and identify miR-31 as a potential target for cSCC treatment...
  15. doi request reprint MicroRNA-203 Inversely Correlates with Differentiation Grade, Targets c-MYC, and Functions as a Tumor Suppressor in cSCC
    Warangkana Lohcharoenkal
    Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    J Invest Dermatol 136:2485-2494. 2016
    ..Restoration of miR-203 expression may provide a therapeutic benefit, particularly in poorly differentiated cSCC...
  16. doi request reprint MicroRNAs in inflammation and response to injuries induced by environmental pollution
    Eniko Sonkoly
    Department of Medicine, Karolinska Institute, Stockholm, Sweden
    Mutat Res 717:46-53. 2011
    ....
  17. doi request reprint Activation of toll-like receptors alters the microRNA expression profile of keratinocytes
    Florian Meisgen
    Unit of Dermatology and Venereology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Exp Dermatol 23:281-3. 2014
    ..These findings suggest an important role for microRNAs in the innate immune response of keratinocytes and provide a basis for further investigations. ..
  18. pmc RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling
    Takashi Shimokawa
    Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden
    RNA Biol 10:321-33. 2013
    ..In conclusion, our findings indicate that RNA editing of GLI1 is a regulatory mechanism that modulates the output of the HH signaling pathway...
  19. doi request reprint Genetic polymorphisms altering microRNA activity in psoriasis--a key to solve the puzzle of missing heritability?
    Andor Pivarcsi
    Unit of Dermatology and Venerology, Department of Medicine, Karolinska Institutet, Stockholm, Sweden
    Exp Dermatol 23:620-4. 2014
    ..In this viewpoint essay, we focus on the emerging new aspects of the role of miRNAs in psoriasis and propose that genetic polymorphisms that affect miRNA activity might be important in the pathogenesis of psoriasis. ..