M Monod

Summary

Affiliation: Centre Hospitalier Universitaire Vaudois
Country: Switzerland

Publications

  1. ncbi request reprint Secreted proteases from pathogenic fungi
    Michel Monod
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Int J Med Microbiol 292:405-19. 2002
  2. ncbi request reprint RNA silencing in the dermatophyte Microsporum canis
    Sandy Vermout
    Department of Infectious and Parasitic Diseases, Parasitology, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    FEMS Microbiol Lett 275:38-45. 2007
  3. ncbi request reprint Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans
    M Monod
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 144:2731-7. 1998
  4. ncbi request reprint Aminopeptidases and dipeptidyl-peptidases secreted by the dermatophyte Trichophyton rubrum
    Michel Monod
    Service de Dermatologie et Venereologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 151:145-55. 2005
  5. ncbi request reprint Secreted proteinases and other virulence mechanisms of Candida albicans
    Michel Monod
    Service de Dermatologie, Laboratoire de Mycologie, BT422, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
    Chem Immunol 81:114-28. 2002
  6. ncbi request reprint Economical microscope configuration for direct mycological examination with fluorescence in dermatology
    M Monod
    Service de Dermatologie, DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Schweiz, Switzerland
    Dermatology 201:246-8. 2000
  7. ncbi request reprint Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene
    D Sanglard
    Institut de Microbiologie Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, Switzerland
    Microbiology 143:405-16. 1997
  8. pmc Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
    D Sanglard
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Antimicrob Agents Chemother 40:2300-5. 1996
  9. pmc Rapid detection of Candida albicans in clinical samples by DNA amplification of common regions from C. albicans-secreted aspartic proteinase genes
    M Flahaut
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Clin Microbiol 36:395-401. 1998
  10. pmc Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
    D Sanglard
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Antimicrob Agents Chemother 39:2378-86. 1995

Collaborators

Detail Information

Publications51

  1. ncbi request reprint Secreted proteases from pathogenic fungi
    Michel Monod
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Int J Med Microbiol 292:405-19. 2002
    ..Knowledge of substrate specificities will increase our understanding about the action of each protease secreted by pathogenic fungi and will help to determine their contribution to virulence...
  2. ncbi request reprint RNA silencing in the dermatophyte Microsporum canis
    Sandy Vermout
    Department of Infectious and Parasitic Diseases, Parasitology, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    FEMS Microbiol Lett 275:38-45. 2007
    ..These results show that RNA silencing can be used for functional genomics in M. canis, and particularly to circumvent the limits and technical difficulties of conventional disruption methods...
  3. ncbi request reprint Differential regulation of SAP8 and SAP9, which encode two new members of the secreted aspartic proteinase family in Candida albicans
    M Monod
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 144:2731-7. 1998
    ..Although the SAP9 gene product has not yet been isolated from cultures of C. albicans, transcripts of SAP9 were observed preferentially in later growth phases when SAP8 expression had decreased...
  4. ncbi request reprint Aminopeptidases and dipeptidyl-peptidases secreted by the dermatophyte Trichophyton rubrum
    Michel Monod
    Service de Dermatologie et Venereologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 151:145-55. 2005
    ..rubrum in a medium containing keratin as the sole nitrogen source. Synergism between endo- and exopeptidases is likely to be essential for dermatophyte virulence, since these fungi grow only in keratinized tissues...
  5. ncbi request reprint Secreted proteinases and other virulence mechanisms of Candida albicans
    Michel Monod
    Service de Dermatologie, Laboratoire de Mycologie, BT422, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
    Chem Immunol 81:114-28. 2002
  6. ncbi request reprint Economical microscope configuration for direct mycological examination with fluorescence in dermatology
    M Monod
    Service de Dermatologie, DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Schweiz, Switzerland
    Dermatology 201:246-8. 2000
    ..Whereas fluorescence microscopy is widely practised in clinical laboratories, it is not generally used in private practice because of the high price of a epifluorescence microscope...
  7. ncbi request reprint Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene
    D Sanglard
    Institut de Microbiologie Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, Switzerland
    Microbiology 143:405-16. 1997
    ..These data demonstrate that CDR2 plays an important role in mediating the resistance of C. albicans to azole antifungal agents...
  8. pmc Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
    D Sanglard
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Antimicrob Agents Chemother 40:2300-5. 1996
    ..The assay used in the present study could be implemented with new antifungal agents and is a powerful tool for assigning these substances as putative substrates of multidrug transporters...
  9. pmc Rapid detection of Candida albicans in clinical samples by DNA amplification of common regions from C. albicans-secreted aspartic proteinase genes
    M Flahaut
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Clin Microbiol 36:395-401. 1998
    ..The two false-positive PCR samples came from patients treated with azole antifungal agents, indicating that PCR was probably able to detect damaged organisms that could not be recovered by culture...
  10. pmc Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters
    D Sanglard
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Antimicrob Agents Chemother 39:2378-86. 1995
    ..cerevisiae mutants lacking specific multidrug transporters which were rendered hypersusceptible to azole derivatives including fluconazole, itraconazole, and ketoconazole...
  11. pmc A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence
    D Sanglard
    Institut de Microbiologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Infect Immun 65:3539-46. 1997
    ..These data suggest that the group of Sap4, Sap5, and Sap6 isoenzymes is important for the normal progression of systemic infection by C. albicans in animals...
  12. pmc Production and characterization of recombinant Aspergillus fumigatus Cu,Zn superoxide dismutase and its recognition by immune human sera
    M D Holdom
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Clin Microbiol 38:558-62. 2000
    ..fumigatus infections were reactive against the recombinant Cu,Zn SOD via immunoenzyme development of Western blots, indicating that the recombinant protein may be useful in the serodiagnostic identification of A. fumigatus infections...
  13. ncbi request reprint Cloning and disruption of the gene encoding an extracellular metalloprotease of Aspergillus fumigatus
    K Jaton-Ogay
    Laboratoire de Mycologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Mol Microbiol 14:917-28. 1994
    ..No difference in pathogenicity was observed between the wild-type strain and the alp mep double mutant, suggesting that ALP and MEP are not essential for the invasion of the lung tissues by A. fumigatus...
  14. doi request reprint Evaluation of a polymerase chain reaction-restriction fragment length polymorphism assay for dermatophyte and nondermatophyte identification in onychomycosis
    O Bontems
    Department of Dermatology, Laboratoire de Mycologie, BT422, Centre Hospitalier Universitaire Vaudois, CH 1011 Lausanne, Switzerland
    Br J Dermatol 161:791-6. 2009
    ..The correct identification of the aetiological agent of nail infections is necessary in order to recommend appropriate treatment...
  15. ncbi request reprint Loss of dipeptidylpeptidase IV activity in chronic rhinosinusitis contributes to the neurogenic inflammation induced by substance P in the nasal mucosa
    Eric Grouzmann
    Division d Hypertension, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
    FASEB J 16:1132-4. 2002
    ....
  16. ncbi request reprint Sulphite efflux pumps in Aspergillus fumigatus and dermatophytes
    Barbara Léchenne
    Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 153:905-13. 2007
    ..Sulphite transporters could be a new target for antifungal drugs in dermatology, since proteolytic digestion of hard keratin would not be possible without prior reduction of disulphide bridges...
  17. doi request reprint Dermatophyte identification in skin and hair samples using a simple and reliable nested polymerase chain reaction assay
    J Verrier
    Department of Dermatology, Centre Hospitalier Universitaire Vaudois, CH 1011 Lausanne, Switzerland
    Br J Dermatol 168:295-301. 2013
    ..The failure of fungi to grow in cultures frequently occurs, especially in cases of previous antifungal therapy...
  18. ncbi request reprint Secreted subtilisin gene family in Trichophyton rubrum
    Olivier Jousson
    Dermatology Service DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Gene 339:79-88. 2004
    ..The set of deduced amino acid sequences of T. rubrum SUB ORFs allowed the identification of orthologous Subs secreted by other dermatophyte species using proteolysis and mass spectrometry...
  19. doi request reprint Secreted proteases from dermatophytes
    Michel Monod
    Service de Dermatologie et Venereologie, Laboratoire de Mycologie, BT422, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland
    Mycopathologia 166:285-94. 2008
    ..Sulphitolysis is likely to be an essential step in the digestion of compact keratinized tissues which precedes the action of all proteases...
  20. ncbi request reprint Secreted aspartic proteases as virulence factors of Candida species
    Michel Monod
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Biol Chem 383:1087-93. 2002
    ..Therefore, the development of specific aspartic protease inhibitors might be of interest for the inhibition of candidiasis...
  21. pmc Functional Characterization of the Pneumocystis jirovecii Potential Drug Targets dhfs and abz2 Involved in Folate Biosynthesis
    A Luraschi
    Institute of Microbiology, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland
    Antimicrob Agents Chemother 59:2560-6. 2015
    ..jirovecii, the dihydrofolate synthase (dhfs) and the aminodeoxychorismate lyase (abz2). The function of these enzymes was demonstrated by the rescue of the null allele of the orthologous gene of Saccharomyces cerevisiae. ..
  22. pmc Gene expression profiling in the human pathogenic dermatophyte Trichophyton rubrum during growth on proteins
    Christophe Zaugg
    Department of Dermatology, Centre Hospitalier Universitaire Vaudois, Av de Beaumont 29, 1011 Lausanne, Switzerland
    Eukaryot Cell 8:241-50. 2009
    ..This broad-scale transcriptional analysis of dermatophytes during growth on proteins reveals new putative pathogenicity-related host adaptation mechanisms of these human pathogenic fungi...
  23. ncbi request reprint Closely related dermatophyte species produce different patterns of secreted proteins
    Karin Giddey
    Dermatology Service, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    FEMS Microbiol Lett 267:95-101. 2007
    ..These results suggest that a switch of habitat could be related to a differential expression of genes encoding homologous secreted proteins...
  24. pmc Secretion of an endogenous subtilisin by Pichia pastoris strains GS115 and KM71
    Karine Salamin
    Service de Dermatologie et Venereologie, Centre Hospitalier Universitaire Vaudois, BT422, 1011 Lausanne, Switzerland
    Appl Environ Microbiol 76:4269-76. 2010
    ..The mutant strain GS115-sub2 was subsequently used as a host for the production of recombinant proteases without endogenous subtilisin contamination...
  25. doi request reprint Trichophyton rubrum secreted and membrane-associated carboxypeptidases
    Christophe Zaugg
    Service de Dermatologie et Venereologie, Laboratoire de Mycologie, BT422, Centre Hospitalier Universitaire Vaudois, CH 1011 Lausanne, Switzerland
    Int J Med Microbiol 298:669-82. 2008
    ....
  26. ncbi request reprint First report of Arthroderma benhamiae in Switzerland
    Janine Fumeaux
    Service de Dermatologie DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Dermatology 208:244-50. 2004
    ..Identification of dermatophytes often remains difficult or uncertain because there are variations from one isolate to another and overlapping characteristics between species...
  27. ncbi request reprint Fast and reliable PCR/sequencing/RFLP assay for identification of fungi in onychomycoses
    Michel Monod
    Department of Dermatology, Centre Hospitalier Universitaire Vaudois, CH 1011 Lausanne, Switzerland
    J Med Microbiol 55:1211-6. 2006
    ..Rapid and reliable molecular identification of the infectious fungus expedites the choice of appropriate antifungal therapy, thereby improving the cure rate of onychomycosis...
  28. ncbi request reprint Comprehensive analysis of proteins secreted by Trichophyton rubrum and Trichophyton violaceum under in vitro conditions
    Karin Giddey
    Service de Dermatologie et Venereologie, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Proteome Res 6:3081-92. 2007
    ..Our findings can contribute to a better understanding of the virulence mechanisms of the two species and the different types of infection they cause...
  29. doi request reprint Choice of an adequate promoter for efficient complementation in Saccharomyces cerevisiae: a case study
    Libera Lo Presti
    Institute of Microbiology, Centre Hospitalier Universitaire Vaudois and University of Lausanne, 1011 Lausanne, Switzerland
    Res Microbiol 160:380-8. 2009
    ..Our results demonstrate that the use of different promoters may prove necessary to obtain successful complementation, with use of the natural promoter being the best approach for homologous complementation...
  30. doi request reprint Pets as the main source of two zoonotic species of the Trichophyton mentagrophytes complex in Switzerland, Arthroderma vanbreuseghemii and Arthroderma benhamiae
    Stéphane Drouot
    Service de Dermatologie, Département Clinique de Médecine Vétérinaire, Faculté Vetsuisse, Universite de Berne, Berne, Switzerland
    Vet Dermatol 20:13-8. 2009
    ..canis. Therefore, it can be suspected that infection with A. vanbreuseghemii occurred during hunting and that the natural source of this dermatophyte is either soil or an animal other than the cat, most probably a rodent...
  31. ncbi request reprint Multiplication of an ancestral gene encoding secreted fungalysin preceded species differentiation in the dermatophytes Trichophyton and Microsporum
    Olivier Jousson
    Dermatology Service DHURDV, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    Microbiology 150:301-10. 2004
    ....
  32. ncbi request reprint Deletion of GEL2 encoding for a beta(1-3)glucanosyltransferase affects morphogenesis and virulence in Aspergillus fumigatus
    Isabelle Mouyna
    Institut Pasteur, Unite des Aspergillus, 25 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Mol Microbiol 56:1675-88. 2005
    ..These data suggest for the first time that beta(1-3)glucanosyltransferase activity is required for both morphogenesis and virulence in A. fumigatus...
  33. pmc Secreted metalloprotease gene family of Microsporum canis
    Frédéric Brouta
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    Infect Immun 70:5676-83. 2002
    ..canis-infected guinea pigs showed that at least MEP2 and MEP3 are produced during the infection process. This is the first report describing the isolation of a gene family encoding potential virulence-related factors in dermatophytes...
  34. ncbi request reprint Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematologic malignancies
    Holger Hebart
    Department of Hematology and Oncology, Institute for Medical Information Processing, Eberhard Karls Universitat Tubingen, Tubingen, Germany
    Blood 100:4521-8. 2002
    ..In conclusion, these results further support the hypothesis that T cells contribute to the host defense against A fumigatus...
  35. ncbi request reprint Biosensor-based screening and characterization of HIV-1 inhibitor interactions with Sap 1, Sap 2, and Sap 3 from Candida albicans
    Dan Backman
    Department of Biochemistry, Uppsala University, Uppsala, Sweden
    J Biomol Screen 11:165-75. 2006
    ..The stepwise biosensor-based strategy was consequently efficient for identification and characterization of new lead compounds for 3 important drug targets...
  36. pmc The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium
    Martin Schaller
    Department of Dermatology and Allergology, University of Munich, Germany
    Infect Immun 71:3227-34. 2003
    ..In contrast the vaginopathic potential of mutants lacking SAP3 or SAP4 to SAP6 was not reduced compared to wild-type cells. These data provide further evidence for a crucial role of Sap1 and Sap2 in C. albicans vaginal infections...
  37. pmc Tetracycline-inducible expression of individual secreted aspartic proteases in Candida albicans allows isoenzyme-specific inhibitor screening
    Peter Staib
    Institut für Molekulare Infektionsbiologie, Universitat Wurzburg, Rontgenring 11, D 97070 Wurzburg, Germany
    Antimicrob Agents Chemother 52:146-56. 2008
    ..Therefore, the strain set can be used to test the activity of new protease inhibitors against individual C. albicans Sap isoenzymes by their ability to block the growth of the pathogen...
  38. ncbi request reprint The crystal structure of the secreted aspartic proteinase 3 from Candida albicans and its complex with pepstatin A
    Claudia Borelli
    Department of Dermatology and Allergy, Ludwig Maximilian University of Munich, Frauenlobstr 9 11, 80337 Munich, Germany
    Proteins 68:738-48. 2007
    ..Inhibitor binding causes active site closure by the movement of a flap segment. Comparison of the structures of Sap3 and Sap2 identifies elements responsible for the specificity of each isoenzyme...
  39. ncbi request reprint Adherence of different Candida dubliniensis isolates in the presence of fluconazole
    Margarete Borg-von Zepelin
    Department of Bacteriology, University Clinics, Gottingen, Germany
    AIDS 16:1237-44. 2002
    ..Like C. albicans, C. dubliniensis secretes aspartic proteinases which in C. albicans have been shown to be involved in adherence...
  40. ncbi request reprint Glycosylphosphatidylinositol-anchored proteases of Candida albicans target proteins necessary for both cellular processes and host-pathogen interactions
    Antje Albrecht
    Robert Koch Institut, Berlin, Germany
    J Biol Chem 281:688-94. 2006
    ..albicans to epithelial cells and caused attenuated epithelial cell damage during experimental oral infection suggesting a unique role for these proteases in both cellular processes and host-pathogen interactions...
  41. ncbi request reprint Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus
    William C Nierman
    The Institute for Genomic Research, Rockville, Maryland 20850, USA
    Nature 438:1151-6. 2005
    ..The Af293 genome sequence provides an unparalleled resource for the future understanding of this remarkable fungus...
  42. pmc Sedolisins, a new class of secreted proteases from Aspergillus fumigatus with endoprotease or tripeptidyl-peptidase activity at acidic pHs
    Utz Reichard
    Department of Medical Microbiology, University Hospital of Gottingen, Kreuzbergring 57, D 37075 Gottingen, Germany
    Appl Environ Microbiol 72:1739-48. 2006
    ..A degradation product of SedA also was observed. A search for genes encoding sedolisin homologues in other fungal genomes indicates that sedolisin gene families are widespread among filamentous ascomycetes...
  43. ncbi request reprint Effect of Micafungin (FK463) on Candida albicans adherence to epithelial cells
    Margarete Borg-von Zepelin
    Department of Bacteriology, Gottingen, Germany
    Chemotherapy 48:148-53. 2002
    ..Adherence is considered a major virulence trait of Candida albicans. FK463 is a new investigational intravenous antifungal of the 'candin family' with potent in vitro and in vivo activity against Candida spp...
  44. ncbi request reprint Isolation of a Microsporum canis gene family encoding three subtilisin-like proteases expressed in vivo
    Frédéric Descamps
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Belgium
    J Invest Dermatol 119:830-5. 2002
    ..canis during the invasion of keratinized structures. This is the first report describing the isolation of a gene family encoding potential virulence-related factors in dermatophytes...
  45. pmc Identification of dermatophyte species by 28S ribosomal DNA sequencing with a commercial kit
    Beatrice Ninet
    Division des maladies infectieuses, Hopital Cantonal Universitaire, 1211 Geneva
    J Clin Microbiol 41:826-30. 2003
    ..Two taxa causing distinct dermatophytoses were clearly distinguished among isolates of the Trichophyton mentagrophytes species complex...
  46. ncbi request reprint [What happens in fungal infections at the molecular level? Fungal pathogens]
    Margarete Borg-von Zepelin
    Abteilung für Bakteriologie Universitätsklinikum Göttingen Kreuzbergring 57, 37075 Gottingen
    Pharm Unserer Zeit 32:110-6. 2003
  47. ncbi request reprint Production of the bullous pemphigoid antigen 230 (BP230) by Saccharomyces cerevisiae and Pichia pastoris
    Emmanuel Laffitte
    Department of Dermatology, University Hospital, Rue Micheli du Crest 24, CH 1211 Geneva 4, Switzerland
    Protein Expr Purif 29:141-7. 2003
    ....
  48. ncbi request reprint Proteome of conidial surface associated proteins of Aspergillus fumigatus reflecting potential vaccine candidates and allergens
    Abdul R Asif
    Department of Clinical Chemistry, University Hospital of Gottingen, Germany
    J Proteome Res 5:954-62. 2006
    ....
  49. ncbi request reprint Adverse effects of incretin therapy for type 2 diabetes
    Eric Grouzmann
    JAMA 298:1759-60; author reply 1760. 2007
  50. ncbi request reprint Humoral and cellular immune response to a Microsporum canis recombinant keratinolytic metalloprotease (r-MEP3) in experimentally infected guinea pigs
    Frédéric Brouta
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, Liege, Belgium
    Med Mycol 41:495-501. 2003
    ..This is the first report on the development of both humoral and cell-mediated immune responses to a purified keratinase in M. canis dermatophytosis...
  51. ncbi request reprint Recombinant expression and antigenic properties of a 31.5-kDa keratinolytic subtilisin-like serine protease from Microsporum canis
    Frédéric Descamps
    Department of Parasitology and Parasitic Diseases, Faculty of Veterinary Medicine, University of Liege, B 43 Sart Tilman, 4000 Liege, Belgium
    FEMS Immunol Med Microbiol 38:29-34. 2003
    ..The heterologous expression of SUB3 provides a valuable tool for addressing further investigations on the role of this keratinase in the specific cellular immune response and on its use in vaccination trials in the cat...