Shan Ling Hung

Summary

Affiliation: National Yang-Ming University
Country: Taiwan

Publications

  1. ncbi request reprint Analysis of the steps involved in Dengue virus entry into host cells
    S L Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    Virology 257:156-67. 1999
  2. ncbi request reprint Analysis of herpes simplex virus entering into cells of oral origin
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, No 155, Sec 2, Li Nong Street, Pei Tou, Taipei, Taiwan
    Virus Res 86:59-69. 2002
  3. ncbi request reprint Effects of safrole on the defensive functions of human neutrophils
    Shan Ling Hung
    Institute of Oral Biology and Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontal Res 38:130-4. 2003
  4. ncbi request reprint Permeability of Streptococcus mutans and Actinobacillus actinomycetemcomitans Through guided tissue regeneration membranes and their effects on attachment of periodontal ligament cells
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 73:843-51. 2002
  5. ncbi request reprint Attachment of periodontal ligament cells to chlorhexidine-loaded guided tissue regeneration membranes
    Yen Ting Chen
    Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontol 74:1652-9. 2003
  6. ncbi request reprint Inhibitory effects of areca nut extracts on phagocytosis of Actinobacillus actinomycetemcomitans ATCC 33384 by neutrophils
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 76:373-9. 2005
  7. ncbi request reprint Attachment of periodontal ligament cells onto various antibiotics-loaded GTR membranes
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    Int J Periodontics Restorative Dent 25:265-75. 2005
  8. doi request reprint Eugenol inhibited the antimicrobial functions of neutrophils
    Dai Chian Chen
    Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Endod 34:176-80. 2008
  9. doi request reprint Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes
    Yu Lin Lai
    Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan
    J Periodontol 81:758-66. 2010
  10. ncbi request reprint Areca nut extracts modulated expression of alkaline phosphatase and receptor activator of nuclear factor kappaB ligand in osteoblasts
    Li Jane Ling
    Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Clin Periodontol 32:353-9. 2005

Collaborators

  • Yu Lin Lai
  • Li Jane Ling
  • Shu Chun Lin
  • Shyh Yuan Lee
  • C L Kao
  • L K Chen
  • Ching Wen Chang
  • Ya Yun Lee
  • Lien Yu Chang
  • Yen Ting Chen
  • Chi Fang Cheng
  • Mei Ju Hsu
  • Shue Fen Yang
  • Dai Chian Chen
  • Yuan Ho Lee
  • Feng Yen Lin
  • Tsung Yun Liu
  • Hsiao Ching Wan
  • Hsuan Hsuan Lu
  • Jung Chen Lin
  • Weng Hang Ho
  • Lin Yang Chi
  • Yu Ching Teng
  • Yi Yun Cheng
  • Kai Ming Wu
  • Chien Sung Tsai
  • Ming Bin Lin
  • Fung Ping Hsiao
  • Yi Wen Lin
  • Chun Yao Huang
  • Chun Ming Shih
  • Tzu Hsuan Yu
  • Nai Wen Tsao
  • Nen Chung Chang
  • I chiang Chou
  • Chi Hang Chan
  • Yi Chen Chen
  • Ching Yi Wu
  • Hsiao Han Chiang
  • Kuo wei Chang
  • Chieh Yuan Cheng
  • Ji Lung Peng
  • Pei Ying Yeh
  • Yu Lin Chen
  • Hen Li Chen
  • Sheng Fang Pai
  • Li Wen Lin
  • Yi Hui Wang

Detail Information

Publications31

  1. ncbi request reprint Analysis of the steps involved in Dengue virus entry into host cells
    S L Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    Virology 257:156-67. 1999
    ..This suggests that cell surface heparan sulfate functions in both viral attachment and penetration of DEN-2 virus. In conclusion, our results further elucidated some aspects of the dengue virus entry process...
  2. ncbi request reprint Analysis of herpes simplex virus entering into cells of oral origin
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, No 155, Sec 2, Li Nong Street, Pei Tou, Taipei, Taiwan
    Virus Res 86:59-69. 2002
    ..In conclusion, our results elucidated some aspects of the HSV entry process into oral cells and revealed some differences in HSV entering into NHOK and GF...
  3. ncbi request reprint Effects of safrole on the defensive functions of human neutrophils
    Shan Ling Hung
    Institute of Oral Biology and Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontal Res 38:130-4. 2003
    ..Inhibition of the defensive functions of neutrophils may be one possible mechanism by which safrole compromises the oral health...
  4. ncbi request reprint Permeability of Streptococcus mutans and Actinobacillus actinomycetemcomitans Through guided tissue regeneration membranes and their effects on attachment of periodontal ligament cells
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 73:843-51. 2002
    ....
  5. ncbi request reprint Attachment of periodontal ligament cells to chlorhexidine-loaded guided tissue regeneration membranes
    Yen Ting Chen
    Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontol 74:1652-9. 2003
    ..The purpose of this study was to evaluate whether the incorporation of chlorhexidine into various GTR membranes improves the attachment of periodontal ligament cells in the presence of Actinobacillus actinomycetemcomitans...
  6. ncbi request reprint Inhibitory effects of areca nut extracts on phagocytosis of Actinobacillus actinomycetemcomitans ATCC 33384 by neutrophils
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 76:373-9. 2005
    ..Little is known about the influence of areca quid on the immune system. This study was to determine the possible effects of the areca nut on phagocytic activity of human neutrophils...
  7. ncbi request reprint Attachment of periodontal ligament cells onto various antibiotics-loaded GTR membranes
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    Int J Periodontics Restorative Dent 25:265-75. 2005
    ..These bacterial effects on cellular attachment could be reversed using the antibiotics-loaded membranes. The information obtained in this study is valuable for the future application of antibiotics-loaded membranes during GTR therapy...
  8. doi request reprint Eugenol inhibited the antimicrobial functions of neutrophils
    Dai Chian Chen
    Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Endod 34:176-80. 2008
    ..These results suggested that the antimicrobial functions of neutrophils were interfered by eugenol, and the inhibitory effects of eugenol (< or = 1.25 mmol/L) were not due to direct killing of neutrophils...
  9. doi request reprint Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes
    Yu Lin Lai
    Department of Stomatology, Taipei Veterans General Hospital, Taipei, Taiwan
    J Periodontol 81:758-66. 2010
    ..This in vitro study investigates the effects of ANE on the production of cyclooxygenase (COX)-2 and the inflammatory mediator prostaglandin E(2) (PGE(2)) by PMNs...
  10. ncbi request reprint Areca nut extracts modulated expression of alkaline phosphatase and receptor activator of nuclear factor kappaB ligand in osteoblasts
    Li Jane Ling
    Faculty of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Clin Periodontol 32:353-9. 2005
    ....
  11. ncbi request reprint Modulation of phagocytosis, chemotaxis, and adhesion of neutrophils by areca nut extracts
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 77:579-85. 2006
    ..This study determined the possible effects of areca nut on phagocytosis, chemotaxis, and adhesion of human neutrophils...
  12. ncbi request reprint Requirements for the upregulation of interleukin-6 by herpes simplex virus-infected gingival fibroblasts
    Yu Ching Teng
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan, 11221
    Viral Immunol 18:170-8. 2005
    ..Collectively, our data suggest that HSV-1 infection of gingival fibroblasts up-regulates production of IL-6 through a mechanism involving the interaction of gD-1 with cellular receptors...
  13. ncbi request reprint Direct binding of herpes simplex virus type 1 virions to complement C3
    Yen Ting Chen
    Faculty of Dentistry, National Yang Ming University, Pei Tou, Taipei, Taiwan
    Viral Immunol 16:347-55. 2003
    ..In addition, the interaction was inhibited by preincubation of purified virions with heparin. In conclusion, a direct interaction of C3 with the HSV-1 virions was demonstrated...
  14. ncbi request reprint Enhancing effects of areca nut extracts on the production of interleukin-6 and interleukin-8 by peripheral blood mononuclear cells
    Lien Yu Chang
    Institute of Clinical Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontol 77:1969-77. 2006
    ..The possible role of oxidative stress of areca nut was also examined...
  15. doi request reprint Areca nut extracts increased the expression of cyclooxygenase-2, prostaglandin E2 and interleukin-1α in human immune cells via oxidative stress
    Lien Yu Chang
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    Arch Oral Biol 58:1523-31. 2013
    ..The role of oxidative stress was also examined...
  16. ncbi request reprint Eugenol suppressed the expression of lipopolysaccharide-induced proinflammatory mediators in human macrophages
    Ya Yun Lee
    Institute of Clinical Dentistry, National Yang Ming University, Taipei, Taiwan
    J Endod 33:698-702. 2007
    ..The results suggest a potential anti-inflammatory effect of eugenol in the acute inflamed pulps and apical periodontitis...
  17. ncbi request reprint The influence of membrane exposure on the outcomes of guided tissue regeneration: clinical and microbiological aspects
    Li Jane Ling
    Department of Periodontics, Taipei Veterans General Hospital and Faculty of Dentistry, Institute of Clinical Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontal Res 38:57-63. 2003
    ..029). In conclusion, membrane exposure resulted in a poor GTR outcome. The amount of A. actinomycetemcomitans on the exposed membrane may be a major contributing factor to the outcome of GTR...
  18. doi request reprint Up-regulation of nucleotide-binding oligomerization domain 1 in inflamed human dental pulp
    Ya Yun Lee
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Endod 37:1370-5. 2011
    ..This study aimed to evaluate the expression of NOD-1 in healthy and inflamed human dental pulps. In addition, the secretion of chemokines induced by NOD-1 and the related signaling pathways were studied...
  19. doi request reprint Inhibitory effects of areca nut extract on expression of complement receptors and fc receptors in human neutrophils
    Ya Yun Lee
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 85:1096-106. 2014
    ..This in vitro study investigates the effects of ANE on complement- and antibody-opsonized phagocytosis by neutrophils. Expression of complement receptors, Fc receptors, and F-actin in ANE-treated neutrophils is also analyzed...
  20. ncbi request reprint Eugenol modulates cyclooxygenase-2 expression through the activation of nuclear factor kappa B in human osteoblasts
    Ya Yun Lee
    Institute of Clinical Dentistry, National Yang Ming University, Taipei, Taiwan
    J Endod 33:1177-82. 2007
    ..Taken together, eugenol might induce COX-2 expression through the activation of NF-kappaB in human osteoblasts. These results suggest that eugenol might be involved in periapical healing by impairing the functions of osteoblasts...
  21. ncbi request reprint Association between human herpesviruses and the severity of periodontitis
    Li Jane Ling
    Department of Periodontics, Taipei Veterans General Hospital, Taipei, Taiwan
    J Periodontol 75:1479-85. 2004
    ..Herpesviruses may play roles in the development of periodontal diseases. The present study evaluated the relationships between herpesviruses and the severity of periodontitis...
  22. doi request reprint Antiherpetic potential of 6-bromoindirubin-3'-acetoxime (BIO-acetoxime) in human oral epithelial cells
    Mei Ju Hsu
    Institute of Oral Biology, National Yang Ming University, No 155, Sec 2, Li Nong St, Pei Tou, Taipei 11221, Taiwan
    Arch Virol 158:1287-96. 2013
    ..Collectively, BIO-acetoxime may suppress viral gene expression and protect oral epithelial cells from HSV-1 infection. These results suggest the possible involvement of GSK-3 in HSV-1 infection...
  23. doi request reprint Inhibitory effects of safrole on phagocytosis, intracellular reactive oxygen species, and the activity of myeloperoxidase released by human polymorphonuclear leukocytes
    Lien Yu Chang
    Department of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Periodontol 80:1330-7. 2009
    ....
  24. doi request reprint Bacterial adhesion to antibiotic-loaded guided tissue regeneration membranes - a scanning electron microscopy study
    Chi Fang Cheng
    Department of Community Dentistry, Zhong Xiao Branch, Taipei City Hospital, Taipei, Taiwan Department of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Formos Med Assoc 114:35-45. 2015
    ..Bacterial contamination of sites undergoing guided tissue regeneration (GTR) therapy may reduce the efficiency of periodontal regeneration. This study compared bacterial adhesion onto various GTR membranes incorporated with antibiotics...
  25. doi request reprint Effects of areca nut extract on lipopolysaccharides-enhanced adhesion and migration of human mononuclear leukocytes
    Lien Yu Chang
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 85:859-67. 2014
    ..The combined effects of nicotine and lipopolysaccharides (LPS) were also analyzed...
  26. doi request reprint Stimulatory effects of glucose and Porphyromonas gingivalis lipopolysaccharide on the secretion of inflammatory mediators from human macrophages
    Shan Ling Hung
    Institute of Oral Biology, National Yang Ming University, Taipei, Taiwan
    J Periodontol 85:140-9. 2014
    ..The purpose of this study is to determine the effects of high glucose in the presence of lipopolysaccharide (LPS) purified from the periodontal pathogen Porphyromonas gingivalis on human macrophages...
  27. ncbi request reprint Osteoblastic response to collagen scaffolds varied in freezing temperature and glutaraldehyde crosslinking
    Dai Chian Chen
    Faculty of Dentistry, National Yang Ming University, No 155, Li Nong St, Sec 2, Peitou, Taipei 112, Taiwan
    J Biomed Mater Res A 80:399-409. 2007
    ..Glutaraldehyde crosslinking process, though improved the dimensional stability of collagen sponges, might compromise the osteoblastic differentiation and mineralization...
  28. doi request reprint Areca nut extract-treated gingival fibroblasts modulate the invasiveness of polymorphonuclear leukocytes via the production of MMP-2
    Hsuan Hsuan Lu
    Institute of Oral Biology, School of Dentistry, National Yang Ming University, Taipei, Taiwan
    J Oral Pathol Med 38:79-86. 2009
    ..This study investigated the potential effects of areca nut extract (ANE) on human gingival fibroblasts and the consequential impacts on inflammatory pathogenesis...
  29. doi request reprint PI3K/Akt signaling mediated apoptosis blockage and viral gene expression in oral epithelial cells during herpes simplex virus infection
    Mei Ju Hsu
    Institute of Oral Biology, National Yang Ming University, No 155, Sec 2, Li Nong St, Pei Tou, Taipei 11221, Taiwan
    Virus Res 153:36-43. 2010
    ..Collectively, these data suggested that, in oral epithelial cells, the HSV-1-induced PI3K/Akt activation was involved in the regulation of apoptosis blockage and viral gene expression...
  30. pmc Porphyromonas gingivalis GroEL induces osteoclastogenesis of periodontal ligament cells and enhances alveolar bone resorption in rats
    Feng Yen Lin
    Division of Cardiology, Taipei Medical University Hospital, Taipei, Taiwan Cardiovascular Research Center, Taipei Medical University Hospital, Taipei, Taiwan Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
    PLoS ONE 9:e102450. 2014
    ..In conclusion, P. gingivalis GroEL may act as a potent virulence factor, contributing to osteoclastogenesis of PDL cells and resulting in periodontal disease with alveolar bone resorption. ..
  31. doi request reprint Bacterial penetration through antibiotic-loaded guided tissue regeneration membranes
    Chi Fang Cheng
    Department of Community Dentistry, Zhong Xiao Branch, Taipei City Hospital, Taipei, Taiwan
    J Periodontol 80:1471-8. 2009
    ..This study compared bacterial penetration through guided tissue regeneration (GTR) membranes impregnated with antibiotics...