Sheikh A Tasduq

Summary

Publications

  1. pmc Negundoside, an irridiod glycoside from leaves of Vitex negundo, protects human liver cells against calcium-mediated toxicity induced by carbon tetrachloride
    Sheikh A Tasduq
    Experimental Toxicology Lab, Division of Pharmacology, Indian Institute of Integrative Medicine, CSIR, Canal Road, Jammu 180001, Jammu and Kashmir, India
    World J Gastroenterol 14:3693-709. 2008
  2. doi request reprint Glycyrrhizic acid prevents ultraviolet-B-induced photodamage: a role for mitogen-activated protein kinases, nuclear factor kappa B and mitochondrial apoptotic pathway
    Quadri Afnan
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India
    Exp Dermatol 25:440-6. 2016
  3. doi request reprint Simultaneous quantification of eight bioactive secondary metabolites from Codonopsis ovata by validated high performance thin layer chromatography and their antioxidant profile
    Alamgir A Dar
    Bioorganic Chemistry Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi 180001, India
    J Pharm Biomed Anal 100:300-8. 2014
  4. doi request reprint Oxidative stress mediated Ca(2+) release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells
    Mufti R Farrukh
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    J Dermatol Sci 75:24-35. 2014
  5. doi request reprint A validated high-performance thin-layer chromatography method for the identification and simultaneous quantification of six markers from Platanus orientalis and their cytotoxic profiles against skin cancer cell lines
    Imran Khan
    Bioorganic Chemistry Division, CSIR Indian Institute of Integrative Medicine, Jammu, Jammu and Kashmir, India
    J Sep Sci 36:2602-10. 2013
  6. doi request reprint Glycyrrhizic acid (GA) inhibits reactive oxygen Species mediated photodamage by blocking ER stress and MAPK pathway in UV-B irradiated human skin fibroblasts
    Mufti Rana Farrukh
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    J Photochem Photobiol B 148:351-7. 2015
  7. doi request reprint Effect of N-acetyl cysteine (NAC), an organosulfur compound from Allium plants, on experimentally induced hepatic prefibrogenic events in Wistar rat
    Ashraf U Nissar
    PK PD and Toxicology Division, Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research, Jammu Tawi, Jammu and Kashmir, India
    Phytomedicine 20:828-33. 2013
  8. doi request reprint Acteoside-mediates chemoprevention of experimental liver carcinogenesis through STAT-3 regulated oxidative stress and apoptosis
    Kaiser J Peerzada
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    Environ Toxicol 31:782-98. 2016
  9. doi request reprint Isolation, cytotoxicity evaluation and HPLC-quantification of the chemical constituents from Artemisia amygdalina Decne
    Shabir H Lone
    Bioorganic Chemistry Division, Indian Institute of Integrative Medicine CSIR, Srinagar 190005, Jammu and Kashmir, India
    J Chromatogr B Analyt Technol Biomed Life Sci 940:135-41. 2013
  10. pmc A Potent Inhibitor of Phosphoinositide 3-Kinase (PI3K) and Mitogen Activated Protein (MAP) Kinase Signalling, Quercetin (3, 3', 4', 5, 7-Pentahydroxyflavone) Promotes Cell Death in Ultraviolet (UV)-B-Irradiated B16F10 Melanoma Cells
    Rather A Rafiq
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    PLoS ONE 10:e0131253. 2015

Collaborators

  • Shashi Bhushan
  • Rajat Sandhir
  • Anil Kumar
  • Nidhi Gupta
  • Parduman R Sharma
  • Rather A Rafiq
  • Quadri Afnan
  • Mufti R Farrukh
  • Peerzada J Kaiser
  • Alamgir A Dar
  • Imran Khan
  • Subhash C Bhardwaj
  • Kaiser J Peerzada
  • Lone A Nazir
  • Love Sharma
  • Mufti Rana Farrukh
  • Payare L Sangwan
  • Surrinder Koul
  • Naresh K Satti
  • Ashraf U Nissar
  • Shabir H Lone
  • Peerzada Kaiser
  • Mushtaq D Adil
  • Aamir H Faridi
  • Bhushan Shashi
  • Ul Ashraf Nissar
  • Kaiser Peerzada
  • Bashir A Ganai
  • Afnan Quadri
  • Shajrul Amin
  • Afnan Qaudri
  • Ul A Nissar
  • Surinder Kitchlu
  • Mohd A Khuroo
  • Jagdish K Dhar
  • Syed Naseer
  • Khursheed A Bhat
  • Hassan S Adil
  • Bhardjwaj C Subhash
  • Rafiq A Rather
  • Ram A Vishwakarma
  • Afzal M Zargar

Detail Information

Publications11

  1. pmc Negundoside, an irridiod glycoside from leaves of Vitex negundo, protects human liver cells against calcium-mediated toxicity induced by carbon tetrachloride
    Sheikh A Tasduq
    Experimental Toxicology Lab, Division of Pharmacology, Indian Institute of Integrative Medicine, CSIR, Canal Road, Jammu 180001, Jammu and Kashmir, India
    World J Gastroenterol 14:3693-709. 2008
    ..To evaluate the protective effect of 2'-p-hydroxybenzoylmussaenosidic acid [negundoside (NG), against carbon tetrachloride (CCl(4))-induced toxicity in HuH-7 cells...
  2. doi request reprint Glycyrrhizic acid prevents ultraviolet-B-induced photodamage: a role for mitogen-activated protein kinases, nuclear factor kappa B and mitochondrial apoptotic pathway
    Quadri Afnan
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Jammu Tawi, Jammu and Kashmir, India
    Exp Dermatol 25:440-6. 2016
    ..Thus, GA has strong potential to be used as a therapeutic/cosmeceutical agent against photodamage. ..
  3. doi request reprint Simultaneous quantification of eight bioactive secondary metabolites from Codonopsis ovata by validated high performance thin layer chromatography and their antioxidant profile
    Alamgir A Dar
    Bioorganic Chemistry Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi 180001, India
    J Pharm Biomed Anal 100:300-8. 2014
    ..9% for DPPH and 43.7% for ABTS) and others at 10 and 25μg/mL, suggesting thereby their apparent potential use for the prevention of free radical induced diseases or as an additive element to food and pharmaceutical industry. ..
  4. doi request reprint Oxidative stress mediated Ca(2+) release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells
    Mufti R Farrukh
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    J Dermatol Sci 75:24-35. 2014
    ....
  5. doi request reprint A validated high-performance thin-layer chromatography method for the identification and simultaneous quantification of six markers from Platanus orientalis and their cytotoxic profiles against skin cancer cell lines
    Imran Khan
    Bioorganic Chemistry Division, CSIR Indian Institute of Integrative Medicine, Jammu, Jammu and Kashmir, India
    J Sep Sci 36:2602-10. 2013
    ..The markers displayed a significant cytotoxic effect against human keratinocyte, mouse melanoma, and human skin epithelial carcinoma cancer cells by using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay...
  6. doi request reprint Glycyrrhizic acid (GA) inhibits reactive oxygen Species mediated photodamage by blocking ER stress and MAPK pathway in UV-B irradiated human skin fibroblasts
    Mufti Rana Farrukh
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    J Photochem Photobiol B 148:351-7. 2015
    ..We have also reported that glycyrrhizic acid (GA) mediates potent photoprotective activity against UV-B - irradiation-induced photodamage in human skin fibroblast...
  7. doi request reprint Effect of N-acetyl cysteine (NAC), an organosulfur compound from Allium plants, on experimentally induced hepatic prefibrogenic events in Wistar rat
    Ashraf U Nissar
    PK PD and Toxicology Division, Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research, Jammu Tawi, Jammu and Kashmir, India
    Phytomedicine 20:828-33. 2013
    ..NAC has also been validated as a model against oxidative burden in chronic liver pathology...
  8. doi request reprint Acteoside-mediates chemoprevention of experimental liver carcinogenesis through STAT-3 regulated oxidative stress and apoptosis
    Kaiser J Peerzada
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    Environ Toxicol 31:782-98. 2016
    ..2015 Wiley Periodicals, Inc. Environ Toxicol 31: 782-798, 2016. ..
  9. doi request reprint Isolation, cytotoxicity evaluation and HPLC-quantification of the chemical constituents from Artemisia amygdalina Decne
    Shabir H Lone
    Bioorganic Chemistry Division, Indian Institute of Integrative Medicine CSIR, Srinagar 190005, Jammu and Kashmir, India
    J Chromatogr B Analyt Technol Biomed Life Sci 940:135-41. 2013
    ..Based on our results, the developed method features good quantification parameters, accuracy, precision and can serve as effective quality control method for standardisation of A. amygdalina Decne. ..
  10. pmc A Potent Inhibitor of Phosphoinositide 3-Kinase (PI3K) and Mitogen Activated Protein (MAP) Kinase Signalling, Quercetin (3, 3', 4', 5, 7-Pentahydroxyflavone) Promotes Cell Death in Ultraviolet (UV)-B-Irradiated B16F10 Melanoma Cells
    Rather A Rafiq
    PK PD and Toxicology Division, CSIR Indian Institute of Integrative Medicine, Canal Road, Jammu Tawi, Jammu and Kashmir, India
    PLoS ONE 10:e0131253. 2015
    ..Overall, these results suggest the possibility of using quercetin in combination with UVB as a possible treatment option for melanoma in future. ..
  11. doi request reprint Effect of Emblica officinalis (fruit) against UVB-induced photo-aging in human skin fibroblasts
    Mushtaq D Adil
    Indian Institute of Integrative Medicine, Council of Scientific and Industrial Research, Canal Road, Jammu Tawi 180001, Jammu and Kashmir India
    J Ethnopharmacol 132:109-14. 2010
    ..It has long been used in Indian folk medicine to treat liver diseases, stomach ulcers, inflammatory diseases, metabolic disorders, geriatric complaints, skin disorders and beauty care...