Upa Kukongviriyapan

Summary

Affiliation: Khon Kaen
Country: Thailand

Publications

  1. doi request reprint Mulberry leaf extract restores arterial pressure in streptozotocin-induced chronic diabetic rats
    Jarinyaporn Naowaboot
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutr Res 29:602-8. 2009
  2. pmc Mamao Pomace Extract Alleviates Hypertension and Oxidative Stress in Nitric Oxide Deficient Rats
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 7:6179-94. 2015
  3. pmc Curcumin protects against cadmium-induced vascular dysfunction, hypertension and tissue cadmium accumulation in mice
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 6:1194-208. 2014
  4. doi request reprint Preventive and therapeutic effects of quercetin on lipopolysaccharide-induced oxidative stress and vascular dysfunction in mice
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Can J Physiol Pharmacol 90:1345-53. 2012
  5. ncbi request reprint Antioxidant and vascular protective activities of Cratoxylum formosum, Syzygium gratum and Limnophila aromatica
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Thailand
    Biol Pharm Bull 30:661-6. 2007
  6. pmc Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells
    Ornanong Tusskorn
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Mitraparb Road, Khon Kaen 40002, Thailand
    BMC Cancer 13:571. 2013
  7. doi request reprint Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension
    Saowanee Nakmareong
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Naunyn Schmiedebergs Arch Pharmacol 383:519-29. 2011
  8. doi request reprint Redox modulation and human bile duct cancer inhibition by curcumin
    Bunliang Suphim
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Food Chem Toxicol 48:2265-72. 2010
  9. doi request reprint Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency
    Saowanee Nakmareong
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Hypertens Res 35:418-25. 2012
  10. pmc Dicoumarol enhances gemcitabine-induced cytotoxicity in high NQO1-expressing cholangiocarcinoma cells
    Benjaporn Buranrat
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    World J Gastroenterol 16:2362-70. 2010

Collaborators

Detail Information

Publications49

  1. doi request reprint Mulberry leaf extract restores arterial pressure in streptozotocin-induced chronic diabetic rats
    Jarinyaporn Naowaboot
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutr Res 29:602-8. 2009
    ..These results provide the first evidence for the efficacy of MA in restoring the vascular reactivity of diabetic rats, the mechanism of which may associate with the alleviation of oxidative stress...
  2. pmc Mamao Pomace Extract Alleviates Hypertension and Oxidative Stress in Nitric Oxide Deficient Rats
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 7:6179-94. 2015
    ..The present results provide evidence for the antihypertensive effect of MP and suggest that MP might be useful as a dietary supplement against hypertension...
  3. pmc Curcumin protects against cadmium-induced vascular dysfunction, hypertension and tissue cadmium accumulation in mice
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 6:1194-208. 2014
    ..These findings suggest that curcumin, due to its antioxidant and chelating properties, is a promising protective agent against hypertension and vascular dysfunction induced by Cd. ..
  4. doi request reprint Preventive and therapeutic effects of quercetin on lipopolysaccharide-induced oxidative stress and vascular dysfunction in mice
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Can J Physiol Pharmacol 90:1345-53. 2012
    ..Overall findings suggest the beneficial effect of quercetin on the prevention and restoration of a failing eNOS system and alleviation of oxidative stress and vascular dysfunction against endotoxin-induced shock in mice...
  5. ncbi request reprint Antioxidant and vascular protective activities of Cratoxylum formosum, Syzygium gratum and Limnophila aromatica
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Thailand
    Biol Pharm Bull 30:661-6. 2007
    ..It was concluded that the plant extracts possess antioxidants and have potential roles in protection of vascular dysfunction...
  6. pmc Phenethyl isothiocyanate induces calcium mobilization and mitochondrial cell death pathway in cholangiocarcinoma KKU-M214 cells
    Ornanong Tusskorn
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Mitraparb Road, Khon Kaen 40002, Thailand
    BMC Cancer 13:571. 2013
    ..We evaluated the effects of PEITC on induction of apoptotic cell death in relation to cellular glutathione (GSH) and mitochondrial function of a CCA cell line, KKU-M214...
  7. doi request reprint Antioxidant and vascular protective effects of curcumin and tetrahydrocurcumin in rats with L-NAME-induced hypertension
    Saowanee Nakmareong
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Naunyn Schmiedebergs Arch Pharmacol 383:519-29. 2011
    ..This study suggests that CUR and THU prevented the development of vascular dysfunction induced by L-NAME and that the effects are associated with alleviation of oxidative stress...
  8. doi request reprint Redox modulation and human bile duct cancer inhibition by curcumin
    Bunliang Suphim
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Food Chem Toxicol 48:2265-72. 2010
    ..The study suggests that curcumin could be developed into an effective chemoprevention against CCA...
  9. doi request reprint Tetrahydrocurcumin alleviates hypertension, aortic stiffening and oxidative stress in rats with nitric oxide deficiency
    Saowanee Nakmareong
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Hypertens Res 35:418-25. 2012
    ..The present study suggests that THC might be used as a dietary supplement to protect against cardiovascular alterations under nitric oxide-deficient conditions...
  10. pmc Dicoumarol enhances gemcitabine-induced cytotoxicity in high NQO1-expressing cholangiocarcinoma cells
    Benjaporn Buranrat
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    World J Gastroenterol 16:2362-70. 2010
    ....
  11. pmc Asiatic acid alleviates hemodynamic and metabolic alterations via restoring eNOS/iNOS expression, oxidative stress, and inflammation in diet-induced metabolic syndrome rats
    Poungrat Pakdeechote
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 6:355-70. 2014
    ..05). In conclusion, asiatic acid improved metabolic, hemodynamic abnormalities in MS rats that could be associated with its antioxidant, anti-inflammatory effects and recovering regulation of eNOS/iNOS expression...
  12. ncbi request reprint Mulberry leaf extract stimulates glucose uptake and GLUT4 translocation in rat adipocytes
    Jarinyaporn Naowaboot
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Am J Chin Med 40:163-75. 2012
    ..These findings are the first molecular evidence supporting the mulberry tea as herbal medicine for diabetic patients...
  13. pmc Crucial role of heme oxygenase-1 on the sensitivity of cholangiocarcinoma cells to chemotherapeutic agents
    Sarinya Kongpetch
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    PLoS ONE 7:e34994. 2012
    ..The results show that HO-1 played a critical role in cytoprotection in CCA cells against chemotherapeutic agents. Targeted inhibition of HO-1 may be a strategy to overcome drug resistance in chemotherapy of bile duct cancer...
  14. doi request reprint Consumption of Syzygium gratum promotes the antioxidant defense system in mice
    Laddawan Senggunprai
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Plant Foods Hum Nutr 65:403-9. 2010
    ..gratum exhibits potent direct antioxidant properties and can induce cytoprotective enzyme in vivo. Consumption of S. gratum may provide a health benefit against oxidative stress and other related disorders...
  15. doi request reprint Phenethyl isothiocyanate induces apoptosis of cholangiocarcinoma cells through interruption of glutathione and mitochondrial pathway
    Ornanong Tusskorn
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 40002
    Naunyn Schmiedebergs Arch Pharmacol 386:1009-16. 2013
    ..It was concluded that disruption of GSH redox but not superoxide formation may be an initial step leading to mitochondrial injury. PEITC could be a promising chemopreventive agent for CCA. ..
  16. ncbi request reprint Protective effects of quercetin against phenylhydrazine-induced vascular dysfunction and oxidative stress in rats
    Saowanee Luangaram
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Food Chem Toxicol 45:448-55. 2007
    ..These results provide the first evidence for the role of the flavonoid, quercetin, in the alleviation of vascular dysfunction in an animal model of PHZ-induced oxidant stress...
  17. doi request reprint Altered vascular function, arterial stiffness, and antioxidant gene responses in pediatric thalassemia patients
    Pantipa Detchaporn
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Pediatr Cardiol 33:1054-60. 2012
    ..These changes were associated with oxidative stress and suggest an adaptive response that serves to protect host cells from further oxidative damage...
  18. doi request reprint Curcumin improves vascular function and alleviates oxidative stress in non-lethal lipopolysaccharide-induced endotoxaemia in mice
    Kwanjit Sompamit
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Eur J Pharmacol 616:192-9. 2009
    ..This study provides the first evidence for the potential role of curcumin in prevention and treatment of vascular dysfunction in mice with endotoxaemia elicited by LPS...
  19. doi request reprint Protective effect of ascorbic acid on cadmium-induced hypertension and vascular dysfunction in mice
    Wanida Donpunha
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Biometals 24:105-15. 2011
    ..Moreover, our study suggests that dietary supplementation of ascorbic acid may provide beneficial effects by reversing the oxidative stress and vascular dysfunction in Cd-induced toxicity...
  20. ncbi request reprint Drug metabolizing enzyme CYP1A2 status in pediatric patients with hemoglobin E-beta thalassemia
    Laddawan Senggunprai
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    J Med Assoc Thai 92:1675-80. 2009
    ..To evaluate the drug metabolizing enzyme CYP1A2 activity in pediatric hemoglobin E-beta-thalassemia patients, since CYP1A2 is responsible for the metabolism of a number of drugs. Alteration of its activity may have clinical consequences...
  21. ncbi request reprint Rice bran protein hydrolysates reduce arterial stiffening, vascular remodeling and oxidative stress in rats fed a high-carbohydrate and high-fat diet
    Ketmanee Senaphan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Eur J Nutr . 2016
    ..This study aimed to investigate whether RBPH could alleviate the metabolic disorders, arterial stiffening, vascular remodeling, and oxidative stress in rats fed a high-carbohydrate and high-fat (HCHF) diet...
  22. ncbi request reprint Endothelial dysfunction and oxidant status in pediatric patients with hemoglobin E-beta thalassemia
    Veerapol Kukongviriyapan
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand 40002
    Pediatr Cardiol 29:130-5. 2008
    ..Endothelial function is impaired in young thalassemia patients, and impaired endothelial function is associated with oxidant stress...
  23. doi request reprint Reversal of cadmium-induced vascular dysfunction and oxidative stress by meso-2,3-dimercaptosuccinic acid in mice
    Kwanjit Sompamit
    Faculty of Medicine, Mahasarakham University, Mahasarakham 44000, Thailand
    Toxicol Lett 198:77-82. 2010
    ..In conclusion, our present study provides the first evidence of the therapeutic efficacy of DMSA against oxidative stress and vascular dysfunction in Cd-intoxicated mice...
  24. doi request reprint Mulberry leaf extract increases adiponectin in murine 3T3-L1 adipocytes
    Jarinyaporn Naowaboot
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutr Res 32:39-44. 2012
    ..Such effects of mulberry leaf extract on adiponectin secretion and adipocyte activity may account for, at least in part, the antidiabetic effects of consumption of beverages containing mulberry leaves...
  25. pmc Synergistic Antihypertensive Effect of Carthamus tinctorius L. Extract and Captopril in L-NAME-Induced Hypertensive Rats via Restoration of eNOS and AT₁R Expression
    Putcharawipa Maneesai
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 8:122. 2016
    ..These data indicate that there are synergistic antihypertensive effects of CT extract and captopril. These effects are likely mediated by their anti-oxidative properties and their inhibition of RAS. ..
  26. doi request reprint Curcumin improves endothelial dysfunction and vascular remodeling in 2K-1C hypertensive rats by raising nitric oxide availability and reducing oxidative stress
    Orachorn Boonla
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nitric Oxide 42:44-53. 2014
    ....
  27. pmc Ferulic Acid Alleviates Changes in a Rat Model of Metabolic Syndrome Induced by High-Carbohydrate, High-Fat Diet
    Ketmanee Senaphan
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 7:6446-64. 2015
    ..Our results suggest that supplementation of FA may have health benefits by minimizing the cardiovascular complications of MS and alleviating its symptoms. ..
  28. doi request reprint Quercetin and EGCG exhibit chemopreventive effects in cholangiocarcinoma cells via suppression of JAK/STAT signaling pathway
    Laddawan Senggunprai
    Department of Pharmacology, Faculty of Medicine, and Liver Fluke and Cholangiocarcinoma Research Center, Khon Kaen University, 40002, Thailand
    Phytother Res 28:841-8. 2014
    ..These results demonstrate beneficial effects of quercetin and EGCG in the suppression of JAK/STAT cascade of CCA cells. Quercetin and EGCG would be potentially useful as cancer chemopreventive agents against CCA...
  29. doi request reprint An alternative exercise and its beneficial effects on glycaemic control and oxidative stress in subjects with type 2 diabetes
    Naruemon Leelayuwat
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Diabetes Res Clin Pract 82:e5-8. 2008
    ..The results suggest a protective effect of the ASE training on vascular complications by improving oxidative stress in according to either improved glycaemic control or exercise per se...
  30. doi request reprint Antihyperglycemic, antioxidant and antiglycation activities of mulberry leaf extract in streptozotocin-induced chronic diabetic rats
    Jarinyaporn Naowaboot
    Department of Pharmacology, Khon Kaen University, Khon Kaen 40002, Thailand
    Plant Foods Hum Nutr 64:116-21. 2009
    ..7 +/- 2.1 microg/ml, respectively. These findings support that long-term administration of MA has antihyperglycemic, antioxidant and antiglycation effects in chronic diabetic rats, which may be beneficial as food supplement for diabetics...
  31. doi request reprint Asiatic acid alleviates cardiovascular remodelling in rats with L-NAME-induced hypertension
    Sarawoot Bunbupha
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Clin Exp Pharmacol Physiol 42:1189-97. 2015
    ....
  32. pmc Rice Bran Protein Hydrolysates Improve Insulin Resistance and Decrease Pro-inflammatory Cytokine Gene Expression in Rats Fed a High Carbohydrate-High Fat Diet
    Kampeebhorn Boonloh
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, 123 Mittraparp Highway, Muang District, Khon Kaen 40002, Thailand
    Nutrients 7:6313-29. 2015
    ..In conclusion, the present findings support the consumption of RBP as a functional food to improve insulin resistance and to prevent the development of metabolic syndrome. ..
  33. pmc Peptides-Derived from Thai Rice Bran Improves Endothelial Function in 2K-1C Renovascular Hypertensive Rats
    Orachorn Boonla
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Nutrients 7:5783-99. 2015
    ..Our results suggest that RBP possesses antihypertensive properties which are mainly due to the inhibition of ACE, and its vasodilatory and antioxidant activity...
  34. pmc Tetrahydrocurcumin protects against cadmium-induced hypertension, raised arterial stiffness and vascular remodeling in mice
    Weerapon Sangartit
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    PLoS ONE 9:e114908. 2014
    ..In this study, we investigated the protective effect of THU against Cd-induced hypertension, raised arterial stiffness and vascular remodeling in mice...
  35. doi request reprint Rice bran protein hydrolysates prevented interleukin-6- and high glucose-induced insulin resistance in HepG2 cells
    Kampeebhorn Boonloh
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Thailand
    Food Funct 6:566-73. 2015
    ..Our results suggested that RBP suppresses inflammatory cytokine signaling and activates AMPK, and thereby these effects may underlie the insulin sensitizing effect. ..
  36. doi request reprint Rice bran protein hydrolysates attenuate diabetic nephropathy in diabetic animal model
    Kampeebhorn Boonloh
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Eur J Nutr . 2016
    ..Our study was to investigate the renoprotective effects of RBP in diabetic animals and mesangial cultured cells...
  37. doi request reprint Tetrahydrocurcumin in combination with deferiprone attenuates hypertension, vascular dysfunction, baroreflex dysfunction, and oxidative stress in iron-overloaded mice
    Weerapon Sangartit
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
    Vascul Pharmacol . 2016
    ..The combination of THU and L1 exerted a greater effect than THU or L1 monotherapy. These results suggest beneficial effects of THU and L1 on iron-induced oxidative stress, hypertension, and vascular dysfunction...
  38. pmc Asiatic acid attenuates renin-angiotensin system activation and improves vascular function in high-carbohydrate, high-fat diet fed rats
    Putcharawipa Maneesai
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    BMC Complement Altern Med 16:123. 2016
    ..In this study, we investigated effects of asiatic acid on vascular structure, vascular function and renin-angiotensin system (RAS) in HCHF diet-induced MS rats...
  39. pmc Ellagic Acid Prevents L-NAME-Induced Hypertension via Restoration of eNOS and p47phox Expression in Rats
    Thewarid Berkban
    Department of Anatomy, Faculty of Medicine, Khon Kaen University, 40002 Khon Kaen, Thailand
    Nutrients 7:5265-80. 2015
    ..Our results indicate that ellagic acid attenuates hypertension by reducing NADPH oxidase subunit p47phox expression, which prevents oxidative stress and restores NO bioavailability...
  40. doi request reprint Asiatic acid reduces blood pressure by enhancing nitric oxide bioavailability with modulation of eNOS and p47phox expression in L-NAME-induced hypertensive rats
    Sarawoot Bunbupha
    Department of Physiology, Faculty of Medicine, Khon Kaen University, 40002, Khon Kaen, Thailand
    Phytother Res 28:1506-12. 2014
    ..Our results are therefore consistent with a model whereby AA reduces blood pressure by enhancing NO bioavailability...
  41. doi request reprint Inflammatory cytokines suppress NAD(P)H:quinone oxidoreductase-1 and induce oxidative stress in cholangiocarcinoma cells
    Auemduan Prawan
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    J Cancer Res Clin Oncol 135:515-22. 2009
    ....
  42. ncbi request reprint Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
    Nuntiya Somparn
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, 40002 Khon Kaen, Thailand
    Eur J Clin Pharmacol 63:43-50. 2007
    ..The impact of the disease on the drug metabolising enzyme cytochrome P450 (CYP) is not known. CYP2E1 and CYP3A4 are responsible for the metabolism of a large number of drugs and changes in their activities may have clinical consequences...
  43. ncbi request reprint Salivary caffeine metabolic ratio in alcohol-dependent subjects
    Veerapol Kukongviriyapan
    Department of Pharmacology and Faculty of Medicine, Khon Kaen University, 40002 Thailand
    Eur J Clin Pharmacol 60:103-7. 2004
    ..To determine whether caffeine (CA) clearance and salivary paraxanthine (PX)/CA ratio were altered in alcohol-dependent subjects and also whether salivary PX/CA ratio was affected by arylamine-N-acetylation 2 ( NAT-2) genotypes...
  44. ncbi request reprint Protective effect of a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 haplotype on coronary artery disease
    Supakanya Lasom
    aBiomedical Sciences Program, Graduate School bCardiovascular Research Group cFaculty of Associated Medical Sciences, Department of Clinical Microscopy dFaculty of Associated Medical Sciences, Department of Clinical Chemistry eFaculty of Medicine, Department of Pathology fFaculty of Medicine, Department of Physiology gQueen Sirikit Heart Center of the Northeast hFaculty of Medicine, Department of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Blood Coagul Fibrinolysis . 2016
    ..ADAMTS13 haplotype had an independent protective effect on CAD and genetic variation of vWF V1565L polymorphism modulates ADAMTS13 activity...
  45. doi request reprint Nrf2 inhibition sensitizes cholangiocarcinoma cells to cytotoxic and antiproliferative activities of chemotherapeutic agents
    Papavee Samatiwat
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, 40002, Thailand
    Tumour Biol 37:11495-507. 2016
    ..Inhibition of Nrf2 could be a novel strategy in enhancing antitumor activity of chemotherapeutic agent in control of resistant cancer. ..
  46. pmc Association of arterial stiffness with single nucleotide polymorphism rs1333049 and metabolic risk factors
    Suphawadee Phababpha
    Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Cardiovasc Diabetol 12:93. 2013
    ..3 in Thai subjects with and without MetS risk factors...
  47. pmc Insulin secretion enhancing activity of roselle calyx extract in normal and streptozotocin-induced diabetic rats
    Eamruthai Wisetmuen
    Department of Pharmacology, Khon Kaen University, Khon Kaen, Thailand
    Pharmacognosy Res 5:65-70. 2013
    ..The present study had, therefore, an objective to investigate the mechanism underlying this activity...
  48. ncbi request reprint Hepatoprotective and antioxidant activities of Tetracera loureiri
    Veerapol Kukongviriyapan
    Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Phytother Res 17:717-21. 2003
    ..These results suggest that T. loureiri may be of potential therapeutic value in some liver disorders...
  49. doi request reprint Oxidative Stress and Cardiovascular Dysfunction Associated with Cadmium Exposure: Beneficial Effects of Curcumin and Tetrahydrocurcumin
    Upa Kukongviriyapan
    Department of Physiology, Faculty of Medicine, Khon Kaen University
    Tohoku J Exp Med 239:25-38. 2016
    ..This review summarizes current knowledge of Cd-induced oxidative stress and cardiovascular dysfunction and a possible protective effect conferred by the antioxidants curcumin and tetrahydrocurcumin...