Robert de Jonge

Summary

Affiliation: Erasmus MC
Country: The Netherlands

Publications

  1. ncbi request reprint Automated counting of white blood cells in synovial fluid
    R de Jonge
    Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Rheumatology (Oxford) 43:170-3. 2004
  2. doi request reprint Evaluation of the new body fluid mode on the Sysmex XE-5000 for counting leukocytes and erythrocytes in cerebrospinal fluid and other body fluids
    Robert de Jonge
    Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Clin Chem Lab Med 48:665-75. 2010
  3. doi request reprint Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia
    Robert de Jonge
    Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands
    Blood 113:2284-9. 2009
  4. ncbi request reprint Automated analysis of pleural fluid total and differential leukocyte counts with the Sysmex XE-2100
    Robert de Jonge
    Department of Clinical Chemistry, Erasmus MC, Rotterdam, The Netherlands
    Clin Chem Lab Med 44:1367-71. 2006
  5. ncbi request reprint Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia
    Robert de Jonge
    Department of Clinical Chemistry and Pediatric Oncology Hematology, Erasmus MC, Rm L 102, POB 2040, 3000 CA Rotterdam, The Netherlands
    Blood 106:717-20. 2005
  6. ncbi request reprint Evaluation of a shorter methionine loading test
    Robert de Jonge
    Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, 3000 CA, Rotterdam, The Netherlands
    Clin Chem Lab Med 42:1027-31. 2004
  7. pmc Prediction of methotrexate intolerance in juvenile idiopathic arthritis: a prospective, observational cohort study
    Evert Hendrik Pieter van Dijkhuizen
    Department of Paediatric Immunology, University Medical Centre Utrecht, Wilhelmina Children s Hospital, Utrecht, The Netherlands Pediatria II, Reumatologia, IRCCS G Gaslini, Largo Gaslini 5, 16147 Genova, Italy
    Pediatr Rheumatol Online J 13:5. 2015
  8. pmc Plasma N-terminal pro-B-type natriuretic peptide as long-term prognostic marker after major vascular surgery
    Harm H H Feringa
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Heart 93:226-31. 2007
  9. doi request reprint Body mass index is an important determinant of methylation biomarkers in women of reproductive ages
    Lydi M J W van Driel
    Department of Obstetrics and Gynecology, Division of Obstetrics and Prenatal Medicine, Erasmus Medical Center, University Medical Centre, Rotterdam, The Netherlands
    J Nutr 139:2315-21. 2009
  10. ncbi request reprint Association of plasma N-terminal pro-B-type natriuretic peptide with postoperative cardiac events in patients undergoing surgery for abdominal aortic aneurysm or leg bypass
    Harm H H Feringa
    Department of Vascular Surgery, Erasmus Medical College, University Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 98:111-5. 2006

Collaborators

Detail Information

Publications31

  1. ncbi request reprint Automated counting of white blood cells in synovial fluid
    R de Jonge
    Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Rheumatology (Oxford) 43:170-3. 2004
    ..To evaluate the performance of automated leucocyte (white blood cell; WBC) counting by comparison with manual counting...
  2. doi request reprint Evaluation of the new body fluid mode on the Sysmex XE-5000 for counting leukocytes and erythrocytes in cerebrospinal fluid and other body fluids
    Robert de Jonge
    Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Clin Chem Lab Med 48:665-75. 2010
    ..We evaluated the body fluid (BF) mode on the new Sysmex XE-5000 analyzer...
  3. doi request reprint Polymorphisms in folate-related genes and risk of pediatric acute lymphoblastic leukemia
    Robert de Jonge
    Clinical Chemistry, Erasmus University Medical Center, Rotterdam, The Netherlands
    Blood 113:2284-9. 2009
    ..2-fold increase in ALL risk (P = .001). For the first time, we associate the RFC1 80G>A and NNMT IVS -151C>T variants to an increased ALL susceptibility...
  4. ncbi request reprint Automated analysis of pleural fluid total and differential leukocyte counts with the Sysmex XE-2100
    Robert de Jonge
    Department of Clinical Chemistry, Erasmus MC, Rotterdam, The Netherlands
    Clin Chem Lab Med 44:1367-71. 2006
    ..Determination of leukocyte (WBC) counts in pleural fluid is routinely performed by microscopic examination. In this study, we evaluated the performance of automated (differential) WBC counting in comparison with manual counting...
  5. ncbi request reprint Effect of polymorphisms in folate-related genes on in vitro methotrexate sensitivity in pediatric acute lymphoblastic leukemia
    Robert de Jonge
    Department of Clinical Chemistry and Pediatric Oncology Hematology, Erasmus MC, Rm L 102, POB 2040, 3000 CA Rotterdam, The Netherlands
    Blood 106:717-20. 2005
    ..SHMT1 1420TT homozygotes only showed decreased MTX sensitivity in the TSI(50, cont). In conclusion, polymorphisms in the folate-related genes MTHFR, MTRR, and SHMT1 are related to MTX resistance in pediatric patients with ALL...
  6. ncbi request reprint Evaluation of a shorter methionine loading test
    Robert de Jonge
    Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, 3000 CA, Rotterdam, The Netherlands
    Clin Chem Lab Med 42:1027-31. 2004
    ..Furthermore, remethylation parameters (MTHFR 677C>T) strongly affect both fasting and post-load homocysteine...
  7. pmc Prediction of methotrexate intolerance in juvenile idiopathic arthritis: a prospective, observational cohort study
    Evert Hendrik Pieter van Dijkhuizen
    Department of Paediatric Immunology, University Medical Centre Utrecht, Wilhelmina Children s Hospital, Utrecht, The Netherlands Pediatria II, Reumatologia, IRCCS G Gaslini, Largo Gaslini 5, 16147 Genova, Italy
    Pediatr Rheumatol Online J 13:5. 2015
    ..The aim of this study was to construct a risk model to predict MTX intolerance...
  8. pmc Plasma N-terminal pro-B-type natriuretic peptide as long-term prognostic marker after major vascular surgery
    Harm H H Feringa
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Heart 93:226-31. 2007
    ..To assess the long-term prognostic value of plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) after major vascular surgery...
  9. doi request reprint Body mass index is an important determinant of methylation biomarkers in women of reproductive ages
    Lydi M J W van Driel
    Department of Obstetrics and Gynecology, Division of Obstetrics and Prenatal Medicine, Erasmus Medical Center, University Medical Centre, Rotterdam, The Netherlands
    J Nutr 139:2315-21. 2009
    ..Thus, the determinants of SAM and SAH differ from those of tHcy concentrations. Given that BMI was a strong determinant of SAM concentrations, it should be included in future studies on cellular methylation...
  10. ncbi request reprint Association of plasma N-terminal pro-B-type natriuretic peptide with postoperative cardiac events in patients undergoing surgery for abdominal aortic aneurysm or leg bypass
    Harm H H Feringa
    Department of Vascular Surgery, Erasmus Medical College, University Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 98:111-5. 2006
    ..Further studies in a larger number of patients are required to confirm these findings...
  11. ncbi request reprint Impact of glomerular filtration rate on minor troponin T elevations for risk assessment in patients undergoing operation for abdominal aortic aneurysm or lower extremity arterial obstruction
    Harm H H Feringa
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Am J Cardiol 98:1515-8. 2006
    ..A currently underestimated high-risk subgroup of patients may be identified using a lower troponin T threshold...
  12. doi request reprint Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs
    Lydi M J W van Driel
    Department of Obstetrics and Gynecology Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 82:474-81. 2008
    ..Whether these polymorphisms are associated with CHDs is not clear. We studied both MTHFR polymorphisms, folate and vitamin B2 by maternal food intake and supplements, and CHD risk...
  13. ncbi request reprint Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele
    Nahid Yazdanpanah
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    J Bone Miner Res 23:86-94. 2008
    ..We found that the MTHFR C677T variant interacts with dietary riboflavin intake to influence fracture risk in women...
  14. doi request reprint Congenital heart defects and biomarkers of methylation in children: a case-control study
    Sylvia A Obermann-Borst
    Department of Obstetrics and Gynaecology Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
    Eur J Clin Invest 41:143-50. 2011
    ..It is not known whether periconception exposure to these metabolic derangements contributes to chromosome segregation and metabolic programming of this pathway in the foetus...
  15. doi request reprint Validation of the body fluid module on the new Sysmex XN-1000 for counting blood cells in cerebrospinal fluid and other body fluids
    Cherina Fleming
    Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Clin Chem Lab Med 50:1791-8. 2012
    ..We evaluated the body fluid (BF) module on the new Sysmex XN-1000 for counting blood cells...
  16. doi request reprint A U-HPLC-ESI-MS/MS-based stable isotope dilution method for the detection and quantitation of methotrexate in plasma
    Ethan den Boer
    Department of Clinical Chemistry, Erasmus MC, Sophia Children s Hospital, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal, Rotterdam, The Netherlands
    Ther Drug Monit 34:432-9. 2012
    ..The authors aimed to develop a liquid chromatography, electrospray ionization, tandem mass spectrometry (LC-ESI-MS/MS)-based method to determine MTX in plasma for therapeutic drug monitoring and pharmacokinetic studies...
  17. doi request reprint ABCB1 and ABCC3 gene polymorphisms are associated with first-year response to methotrexate in juvenile idiopathic arthritis
    Maurits C F J de Rotte
    Department of Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    J Rheumatol 39:2032-40. 2012
    ..To individualize treatment strategies, the genetic determinants of response to MTX should be identified...
  18. ncbi request reprint Detection and allele-frequencies of the 833T>C, 844ins68 and a novel mutation in the cystathionine beta-synthase gene
    Pieter H Griffioen
    Department of Clinical Chemistry Erasmus MC, University Medical Center Rotterdam, P O Box 2040, 3000 CA Rotterdam, The Netherlands
    Clin Chim Acta 354:191-4. 2005
    ..However, allele frequency and effects of the isolated 833T>C mutation are unclear...
  19. ncbi request reprint Dietary intake of B-vitamins in mothers born a child with a congenital heart defect
    Anna C Verkleij-Hagoort
    Dept of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus MC, University Medical Centre, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    Eur J Nutr 45:478-86. 2006
    ..Periconceptional use of multivitamins reduces the risk of a child with a congenital heart defect (CHD). Data on the impact of maternal diet, however, are lacking...
  20. doi request reprint Effect of methotrexate use and erythrocyte methotrexate polyglutamate on glycosylated hemoglobin in rheumatoid arthritis
    Maurits C F J de Rotte
    Erasmus University Medical Center, Rotterdam, The Netherlands
    Arthritis Rheumatol 66:2026-36. 2014
    ....
  21. doi request reprint Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in patients with rheumatoid arthritis
    Maurits C F J de Rotte
    Department of Clinical Chemistry, Erasmus University Medical Center, Rotterdam, Netherlands
    Ann Rheum Dis 74:408-14. 2015
    ..To investigate if erythrocyte-methotrexate-polyglutamate (MTX-PG) concentrations in patients with rheumatoid arthritis (RA) are associated with disease activity or adverse events...
  22. doi request reprint Biomarkers of the one-carbon pathway in association with congenital diaphragmatic hernia
    Leonardus W J E Beurskens
    Department of Pediatric Surgery, Sophia Children s Hospital, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Birth Defects Res A Clin Mol Teratol 94:557-60. 2012
    ..In conclusion, the biomarkers of methylation determined in cord blood are not associated with CDH risk. Maternal and child characteristics could not predict newborn biomarker concentrations of the 1-C pathway...
  23. doi request reprint Evaluation of Sysmex XN-1000 High-Sensitive Analysis (hsA) Research Mode for Counting and Differentiating Cells in Cerebrospinal Fluid
    Cherina Fleming
    From the Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Am J Clin Pathol 145:299-307. 2016
    ..We evaluated this mode by counting RBCs, WBCs, and differentiated WBCs in CSF samples...
  24. doi request reprint Determinants of erythrocyte methotrexate polyglutamate levels in rheumatoid arthritis
    Ethan den Boer
    From the Department of Clinical Chemistry Department of Rheumatology Department of Pediatric Hemato Oncology Erasmus University Medical Center, Rotterdam, the Netherlands E den Boer, MSc M C J F de Rotte, PharmD S G Heil, PhD R de Jonge, PhD, Department of Clinical Chemistry J M Hazes, MD, PhD, Department of Rheumatology S M F Pluijm, PhD, Department of Pediatric Hemato Oncology, Erasmus University Medical Center
    J Rheumatol 41:2167-78. 2014
    ..We aimed to define the determinants of erythrocyte MTX-PG concentrations in 2 prospective cohorts of patients with RA...
  25. doi request reprint Assessment of intracellular methotrexate and methotrexate-polyglutamate metabolite concentrations in erythrocytes by ultrafast matrix-assisted laser desorption/ionization triple quadrupole tandem mass spectrometry
    Roland J W Meesters
    Department of Neurology, University Medical Center Rotterdam ErasmusMC, Rotterdam, The Netherlands
    Rapid Commun Mass Spectrom 25:3063-70. 2011
    ..The highest observed glutamylation degree of MTX was MTXPG5, the very long chain MTX-polyglutamate metabolites MTXPG6 and MTXPG7 were not detected in the packed erythrocyte pellets collected from rheumatoid arthritis patients...
  26. doi request reprint The impact of early- and late-onset preeclampsia on umbilical cord blood cell populations
    Emilie M Herzog
    Department of Obstetrics and Gynaecology, Erasmus MC, University Medical Centre Rotterdam, Postbus 2040, 3000 CA Rotterdam, The Netherlands Electronic address
    J Reprod Immunol 116:81-5. 2016
    ..This heterogeneity in UCBC should be considered as confounder in epigenetic association studies examining EOPE. ..
  27. doi request reprint Screening for metabolic vitamin B12 deficiency by holotranscobalamin in patients suspected of vitamin B12 deficiency: a multicentre study
    Sandra G Heil
    Department of Clinical Chemistry, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Clin Biochem 49:184-9. 2012
    ..The aim of this study was to validate the clinical usefulness of holotranscobalamin (holoTC) as an initial screening assay for metabolic vitamin B(12) deficiency in a mixed patient population...
  28. ncbi request reprint Homocysteine levels and the risk of osteoporotic fracture
    Joyce B J van Meurs
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    N Engl J Med 350:2033-41. 2004
    ..We therefore hypothesized that mildly elevated homocysteine levels might be related to age-related osteoporotic fractures...
  29. doi request reprint A stable isotope dilution LC-ESI-MS/MS method for the quantification of pyridoxal-5'-phosphate in whole blood
    Bertrand D van Zelst
    Department of Clinical Chemistry, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    J Chromatogr B Analyt Technol Biomed Life Sci 903:134-41. 2012
    ..The comparison with the current HPLC method is excellent although a significant proportional bias was detected. To conclude, the LC-ESI-MS/MS method is an appropriate method to determine PLP in whole blood...
  30. doi request reprint Acute kidney injury in patients presenting with hyponatremia
    Denise Adams
    Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
    J Nephrol 24:749-55. 2011
    ..Hyponatremia is the most common electrolyte disorder, but a lack of well-characterized cohorts is hindering a full appreciation of this complex and heterogeneous disorder...
  31. ncbi request reprint Baseline plasma N-terminal pro-B-type natriuretic peptide is associated with the extent of stress-induced myocardial ischemia during dobutamine stress echocardiography
    Harm H H Feringa
    Department of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands
    Coron Artery Dis 17:255-9. 2006
    ..To determine the relationship between baseline plasma N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels and the presence and extent of myocardial ischemia during dobutamine stress echocardiography (DSE)...