Threes G M Smijs

Summary

Affiliation: Leiden University Medical Center
Country: The Netherlands

Publications

  1. doi request reprint Preclinical studies with 5,10,15-Tris(4-methylpyridinium)-20-phenyl-[21H,23H]-porphine trichloride for the photodynamic treatment of superficial mycoses caused by Trichophyton rubrum
    Threes G M Smijs
    Leiden University Medical Centre, The Netherlands
    Photochem Photobiol 85:733-9. 2009
  2. ncbi request reprint Photodynamic inactivation of the dermatophyte Trichophyton rubrum
    Threes G M Smijs
    Sylvius Laboratory, Leiden University Medical Centre, Leiden, The Netherlands
    Photochem Photobiol 77:556-60. 2003
  3. ncbi request reprint Development of a test system for mutagenicity of photosensitizers using Drosophila melanogaster
    Threes G M Smijs
    Leiden University Medical Centre, Sylvius Laboratory, Wassenaarseweg 72, 2333 AL, Leiden, The Netherlands
    Photochem Photobiol 79:332-8. 2004
  4. ncbi request reprint Photodynamic treatment of the dermatophyte Trichophyton rubrum and its microconidia with porphyrin photosensitizers
    Threes G M Smijs
    Department of Ophthamology, Leiden University Medical Centre, 2333 AL Leiden, The Netherlands
    Photochem Photobiol 80:197-202. 2004
  5. ncbi request reprint A novel ex vivo skin model to study the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment in different growth phases
    Threes G M Smijs
    Leiden University Medical Centre, Skin Research Laboratory, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Antimicrob Chemother 59:433-40. 2007
  6. ncbi request reprint Investigation of conditions involved in the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment
    Threes G M Smijs
    Leiden University Medical Centre, Leiden, The Netherlands
    J Antimicrob Chemother 60:750-9. 2007
  7. doi request reprint Morphological changes of the dermatophyte Trichophyton rubrum after photodynamic treatment: a scanning electron microscopy study
    Threes G M Smijs
    Leiden University Medical Centre, Leiden, The Netherlands
    Med Mycol 46:315-25. 2008

Collaborators

Detail Information

Publications7

  1. doi request reprint Preclinical studies with 5,10,15-Tris(4-methylpyridinium)-20-phenyl-[21H,23H]-porphine trichloride for the photodynamic treatment of superficial mycoses caused by Trichophyton rubrum
    Threes G M Smijs
    Leiden University Medical Centre, The Netherlands
    Photochem Photobiol 85:733-9. 2009
    ..Therefore, PDT with 10 microm Sylsens B (formulation I) and 18 J/cm(2) UVA-1 could be considered as effective and safe. This offers the possibility to perform clinical studies in future...
  2. ncbi request reprint Photodynamic inactivation of the dermatophyte Trichophyton rubrum
    Threes G M Smijs
    Sylvius Laboratory, Leiden University Medical Centre, Leiden, The Netherlands
    Photochem Photobiol 77:556-60. 2003
    ..For Sylsens B and DP mme, which displayed the best results, a concentration-dependent uptake by T. rubrum was established...
  3. ncbi request reprint Development of a test system for mutagenicity of photosensitizers using Drosophila melanogaster
    Threes G M Smijs
    Leiden University Medical Centre, Sylvius Laboratory, Wassenaarseweg 72, 2333 AL, Leiden, The Netherlands
    Photochem Photobiol 79:332-8. 2004
    ..We demonstrated that TPP was mutagenic using the Photo-SMART. For hematoporphyrin, the results of the Photo-SMART indicate the absence of mutagenicity...
  4. ncbi request reprint Photodynamic treatment of the dermatophyte Trichophyton rubrum and its microconidia with porphyrin photosensitizers
    Threes G M Smijs
    Department of Ophthamology, Leiden University Medical Centre, 2333 AL Leiden, The Netherlands
    Photochem Photobiol 80:197-202. 2004
    ..These results offer the ingredients for a future treatment of fungal infections, including those of the nail...
  5. ncbi request reprint A novel ex vivo skin model to study the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment in different growth phases
    Threes G M Smijs
    Leiden University Medical Centre, Skin Research Laboratory, PO Box 9600, 2300 RC Leiden, The Netherlands
    J Antimicrob Chemother 59:433-40. 2007
    ..rubrum when using red light...
  6. ncbi request reprint Investigation of conditions involved in the susceptibility of the dermatophyte Trichophyton rubrum to photodynamic treatment
    Threes G M Smijs
    Leiden University Medical Centre, Leiden, The Netherlands
    J Antimicrob Chemother 60:750-9. 2007
    ....
  7. doi request reprint Morphological changes of the dermatophyte Trichophyton rubrum after photodynamic treatment: a scanning electron microscopy study
    Threes G M Smijs
    Leiden University Medical Centre, Leiden, The Netherlands
    Med Mycol 46:315-25. 2008
    ..In case of a non-lethal PDT, fungal re-growth started on the remnants of the treated mycelium...