J Kortekaas

Summary

Affiliation: Wageningen University
Country: The Netherlands

Publications

  1. doi request reprint Comparative efficacy of two next-generation Rift Valley fever vaccines
    J Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre CVI WUR, P O Box 65, 8200 AB Lelystad, The Netherlands Electronic address
    Vaccine 32:4901-8. 2014
  2. doi request reprint One Health approach to Rift Valley fever vaccine development
    Jeroen Kortekaas
    Department of Virology, Central Veterinary Institute, part of Wageningen University and Research Centre, P O Box 65, 8200 AB Lelystad, The Netherlands Electronic address
    Antiviral Res 106:24-32. 2014
  3. pmc A single vaccination with an improved nonspreading Rift Valley fever virus vaccine provides sterile immunity in lambs
    Nadia Oreshkova
    Department of Virology, Central Veterinary Institute, part of Wageningen University and Research Centre, Lelystad, The Netherlands Department of Infectious Diseases and Immunology, Virology Division, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 8:e77461. 2013
  4. pmc Rift valley Fever vaccine development, progress and constraints
    Jeroen Kortekaas
    Central Veterinary Institute of Wageningen University and Research Centre, Lelystad, The Netherlands
    Emerg Infect Dis 17:e1. 2011
  5. doi request reprint European ring trial to evaluate ELISAs for the diagnosis of infection with Rift Valley fever virus
    Jeroen Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre, Lelystad, The Netherlands
    J Virol Methods 187:177-81. 2013
  6. doi request reprint Efficacy of three candidate Rift Valley fever vaccines in sheep
    J Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre, 8200 AB Lelystad, The Netherlands
    Vaccine 30:3423-9. 2012
  7. pmc Creation of a nonspreading Rift Valley fever virus
    Jeroen Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University Research Centre, Edelhertweg 15, 8219 PH Lelystad, The Netherlands
    J Virol 85:12622-30. 2011
  8. doi request reprint Protective efficacy of a Classical swine fever virus C-strain deletion mutant and ability to differentiate infected from vaccinated animals
    J Kortekaas
    Virology Division, Central Veterinary Institute of Wageningen University Research Center, P O Box 65, 8200 AB Lelystad, The Netherlands
    Vet Microbiol 147:11-8. 2011
  9. doi request reprint Rift Valley fever virus immunity provided by a paramyxovirus vaccine vector
    J Kortekaas
    Central Veterinary Institute of Wageningen University Research Centre, AB Lelystad, The Netherlands
    Vaccine 28:4394-401. 2010
  10. doi request reprint Intramuscular inoculation of calves with an experimental Newcastle disease virus-based vector vaccine elicits neutralizing antibodies against Rift Valley fever virus
    J Kortekaas
    Virology Division, Cluster of Mammalian Virology, Central Veterinary Institute of Wageningen University Research Centre, P O Box 65, 8200 AB Lelystad, The Netherlands
    Vaccine 28:2271-6. 2010

Collaborators

Detail Information

Publications16

  1. doi request reprint Comparative efficacy of two next-generation Rift Valley fever vaccines
    J Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre CVI WUR, P O Box 65, 8200 AB Lelystad, The Netherlands Electronic address
    Vaccine 32:4901-8. 2014
    ..Two lambs vaccinated with R566 developed mild fever after challenge infection, which was associated with low levels of viral RNA in the blood, whereas vaccination with the NSR-Gn vaccine completely prevented viremia and clinical signs. ..
  2. doi request reprint One Health approach to Rift Valley fever vaccine development
    Jeroen Kortekaas
    Department of Virology, Central Veterinary Institute, part of Wageningen University and Research Centre, P O Box 65, 8200 AB Lelystad, The Netherlands Electronic address
    Antiviral Res 106:24-32. 2014
    ..This paper reviews the historical impact of RVFV on human health and proposes strategies to develop and license a next-generation vaccine for both animals and humans. ..
  3. pmc A single vaccination with an improved nonspreading Rift Valley fever virus vaccine provides sterile immunity in lambs
    Nadia Oreshkova
    Department of Virology, Central Veterinary Institute, part of Wageningen University and Research Centre, Lelystad, The Netherlands Department of Infectious Diseases and Immunology, Virology Division, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    PLoS ONE 8:e77461. 2013
    ..The combined results suggest that sterile immunity was achieved by a single vaccination with the NSR-Gn vaccine. ..
  4. pmc Rift valley Fever vaccine development, progress and constraints
    Jeroen Kortekaas
    Central Veterinary Institute of Wageningen University and Research Centre, Lelystad, The Netherlands
    Emerg Infect Dis 17:e1. 2011
    ..These recommendations and other meeting documents are available at www.fao.org/ag/againfo/programmes/en/empres/RVF_2011.html...
  5. doi request reprint European ring trial to evaluate ELISAs for the diagnosis of infection with Rift Valley fever virus
    Jeroen Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre, Lelystad, The Netherlands
    J Virol Methods 187:177-81. 2013
    ..More extensive validations with sera of known IgM status are, however, required to determine agreement between IgM ELISAs...
  6. doi request reprint Efficacy of three candidate Rift Valley fever vaccines in sheep
    J Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre, 8200 AB Lelystad, The Netherlands
    Vaccine 30:3423-9. 2012
    ..A single vaccination with each vaccine resulted in a neutralizing antibody response within three weeks after vaccination and protected lambs from viremia, pyrexia and mortality...
  7. pmc Creation of a nonspreading Rift Valley fever virus
    Jeroen Kortekaas
    Department of Virology, Central Veterinary Institute of Wageningen University Research Centre, Edelhertweg 15, 8219 PH Lelystad, The Netherlands
    J Virol 85:12622-30. 2011
    ..The methods reported here will greatly facilitate vaccine and drug development as well as fundamental studies on RVFV biology. Moreover, it may be possible to develop similar systems for other members of the bunyavirus family as well...
  8. doi request reprint Protective efficacy of a Classical swine fever virus C-strain deletion mutant and ability to differentiate infected from vaccinated animals
    J Kortekaas
    Virology Division, Central Veterinary Institute of Wageningen University Research Center, P O Box 65, 8200 AB Lelystad, The Netherlands
    Vet Microbiol 147:11-8. 2011
    ..Analysis of the sera, however, demonstrated that a commercially available E2 ELISA was unsuitable as an accompanying DIVA test...
  9. doi request reprint Rift Valley fever virus immunity provided by a paramyxovirus vaccine vector
    J Kortekaas
    Central Veterinary Institute of Wageningen University Research Centre, AB Lelystad, The Netherlands
    Vaccine 28:4394-401. 2010
    ..We also demonstrate that a single intramuscular vaccination of lambs, the main target species of RVFV, is sufficient to elicit a neutralizing antibody response...
  10. doi request reprint Intramuscular inoculation of calves with an experimental Newcastle disease virus-based vector vaccine elicits neutralizing antibodies against Rift Valley fever virus
    J Kortekaas
    Virology Division, Cluster of Mammalian Virology, Central Veterinary Institute of Wageningen University Research Centre, P O Box 65, 8200 AB Lelystad, The Netherlands
    Vaccine 28:2271-6. 2010
    ..The RVFV-neutralizing activity of the antisera from intramuscularly vaccinated calves was demonstrated, suggesting that NDV is a promising vaccine vector for the prevention of RVF in calves...
  11. doi request reprint Rational design of a classical swine fever C-strain vaccine virus that enables the differentiation between infected and vaccinated animals
    J Kortekaas
    Virology Division, Central Veterinary Institute of Wageningen University Research Centre, P O Box 65, 8200 AB Lelystad, The Netherlands
    J Virol Methods 163:175-85. 2010
    ..The findings provide the molecular basis for the development of a novel, genetically stable, live attenuated CSF DIVA vaccine...
  12. doi request reprint Rift Valley fever virus subunit vaccines confer complete protection against a lethal virus challenge
    S M de Boer
    Central Veterinary Institute of Wageningen University and Research Centre, Cluster of Mammalian Virology, Edelhertweg 15, 8219 PH, Lelystad, The Netherlands
    Vaccine 28:2330-9. 2010
    ..Importantly, absence of the nucleocapsid protein in either vaccine candidate facilitates the differentiation between infected and vaccinated animals using a commercial recombinant nucleocapsid protein-based indirect ELISA...
  13. pmc Acid-activated structural reorganization of the Rift Valley fever virus Gc fusion protein
    S M de Boer
    Department of Infectious Diseases and Immunology, Virology Division, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    J Virol 86:13642-52. 2012
    ..In conclusion, our data suggest that after endocytic uptake, RVFV traffics to the acidic late endolysosomal compartments, where histidine protonation drives the reorganization of the Gc fusion protein that leads to membrane fusion...
  14. pmc Heparan sulfate facilitates Rift Valley fever virus entry into the cell
    S M de Boer
    Department of Infectious Diseases and Immunology, Virology Division, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
    J Virol 86:13767-71. 2012
    ..Entry was significantly reduced by preincubating the virus inoculum with highly sulfated heparin, by enzymatic removal of heparan sulfate from cells and in cells genetically deficient in heparan sulfate synthesis...
  15. doi request reprint Vertical transmission of rift valley fever virus without detectable maternal viremia
    A F G Antonis
    Central Veterinary Institute of Wageningen University Research Centre, Lelystad, The Netherlands
    Vector Borne Zoonotic Dis 13:601-6. 2013
    ..We demonstrate that RVFV can be transmitted vertically in the absence of detectable maternal viremia...
  16. doi request reprint Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigen
    N Oreshkova
    Department of Virology, Central Veterinary Institute of Wageningen University and Research Centre, Lelystad, The Netherlands Department of Infectious Diseases and Immunology, Virology Division, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands Electronic address
    Vaccine 32:5323-9. 2014
    ..Interestingly, whereas intramuscular vaccination elicited superior systemic immune responses, intranasal vaccination provided optimal clinical protection. ..