Oyindamola O Abiodun

Summary

Country: UK

Publications

  1. doi request reprint Comparison of SYBR Green I-, PicoGreen-, and [3H]-hypoxanthine-based assays for in vitro antimalarial screening of plants from Nigerian ethnomedicine
    Oyindamola O Abiodun
    Department of Pharmacology and Therapeutics, College of Health Sciences, Ladoke Akintola University of Technology, Oshogbo, Nigeria
    Parasitol Res 106:933-9. 2010
  2. doi request reprint Antitrypanosomal activity of some medicinal plants from Nigerian ethnomedicine
    Oyindamola O Abiodun
    Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
    Parasitol Res 110:521-6. 2012
  3. doi request reprint In vitro antiplasmodial activity and toxicity assessment of some plants from Nigerian ethnomedicine
    Oyindamola Abiodun
    Department of Pharmacology and Therapeutics, College of Health Sciences, Ladoke Akintola University of Technology, Oshogbo, Nigeria
    Pharm Biol 49:9-14. 2011
  4. pmc Different patterns of pfcrt and pfmdr1 polymorphisms in P. falciparum isolates from Nigeria and Brazil: the potential role of antimalarial drug selection pressure
    Grace O Gbotosho
    Malaria Research Laboratories, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Nigeria
    Am J Trop Med Hyg 86:211-3. 2012
  5. pmc Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance
    Obaro S Michael
    Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
    Malar J 9:335. 2010
  6. ncbi request reprint Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo
    Akintunde Sowunmi
    Department of Pharmacology and Therapeutics, Institute for Medical Research and Training, University of Ibadan, Ibadan, Nigeria
    Mem Inst Oswaldo Cruz 102:417-9. 2007
  7. pmc In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains
    Oyindamola O Abiodun
    Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
    Malar J 12:43. 2013
  8. doi request reprint In vivo antimalarial activity of Trichilia megalantha harms extracts and fractions in animal models
    Dorcas A Fadare
    Department of Pharmacognosy, University of Ibadan, Ibadan, Nigeria
    Parasitol Res 112:2991-5. 2013
  9. pmc Rapid detection of lactate dehydrogenase and genotyping of Plasmodium falciparum in saliva of children with acute uncomplicated malaria
    Grace O Gbotosho
    Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Am J Trop Med Hyg 83:496-501. 2010
  10. pmc Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa
    Christian T Happi
    Malaria Research Laboratories, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Nigeria
    Malar J 5:82. 2006

Collaborators

Detail Information

Publications15

  1. doi request reprint Comparison of SYBR Green I-, PicoGreen-, and [3H]-hypoxanthine-based assays for in vitro antimalarial screening of plants from Nigerian ethnomedicine
    Oyindamola O Abiodun
    Department of Pharmacology and Therapeutics, College of Health Sciences, Ladoke Akintola University of Technology, Oshogbo, Nigeria
    Parasitol Res 106:933-9. 2010
    ..SG appears to be a cost-effective alternative for antimalarial drug screening and a viable technique that may facilitate antimalarial drug discovery process especially in developing countries...
  2. doi request reprint Antitrypanosomal activity of some medicinal plants from Nigerian ethnomedicine
    Oyindamola O Abiodun
    Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
    Parasitol Res 110:521-6. 2012
    ..catappa and T. orientalis against T. brucei rhodesiense (STIB 900) is being reported for the first time in Nigerian ethnomedicine, and these plants could be a potential source of antitrypanosomal agents...
  3. doi request reprint In vitro antiplasmodial activity and toxicity assessment of some plants from Nigerian ethnomedicine
    Oyindamola Abiodun
    Department of Pharmacology and Therapeutics, College of Health Sciences, Ladoke Akintola University of Technology, Oshogbo, Nigeria
    Pharm Biol 49:9-14. 2011
    ..Ethnomedicine has been shown to be a potential source of antimalarial compounds or source of template for the synthesis of novel antimalarial molecules...
  4. pmc Different patterns of pfcrt and pfmdr1 polymorphisms in P. falciparum isolates from Nigeria and Brazil: the potential role of antimalarial drug selection pressure
    Grace O Gbotosho
    Malaria Research Laboratories, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Nigeria
    Am J Trop Med Hyg 86:211-3. 2012
    ..Continuous monitoring of pfcrt SVMNT haplotype is required in endemic areas of Africa, where artesunate-amodiaquine combination is used for treatment of acute uncomplicated malaria...
  5. pmc Early variations in plasmodium falciparum dynamics in Nigerian children after treatment with two artemisinin-based combinations: implications on delayed parasite clearance
    Obaro S Michael
    Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
    Malar J 9:335. 2010
    ..The study protocol was designed to evaluate more closely the early effects and the standard measures of efficacies of these two regimens...
  6. ncbi request reprint Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo
    Akintunde Sowunmi
    Department of Pharmacology and Therapeutics, Institute for Medical Research and Training, University of Ibadan, Ibadan, Nigeria
    Mem Inst Oswaldo Cruz 102:417-9. 2007
    ..This suggests a potential clinical application of the reversal phenomenon...
  7. pmc In vitro interaction of artemisinin derivatives or the fully synthetic peroxidic anti-malarial OZ277 with thapsigargin in Plasmodium falciparum strains
    Oyindamola O Abiodun
    Department of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
    Malar J 12:43. 2013
    ..The latter compound is an adamantane-based peroxide and the first fully synthetic clinical candidate recently registered in India by Ranbaxy Laboratories Ltd. for anti-malarial combination therapy...
  8. doi request reprint In vivo antimalarial activity of Trichilia megalantha harms extracts and fractions in animal models
    Dorcas A Fadare
    Department of Pharmacognosy, University of Ibadan, Ibadan, Nigeria
    Parasitol Res 112:2991-5. 2013
    ..45 ± 0.6 days). The animals that were treated with Chloroquine had mean survival time of 23.5 ± 1.2 days...
  9. pmc Rapid detection of lactate dehydrogenase and genotyping of Plasmodium falciparum in saliva of children with acute uncomplicated malaria
    Grace O Gbotosho
    Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Am J Trop Med Hyg 83:496-501. 2010
    ..0005). Mutant T76 allele was detectable in 60% and 57% of blood and saliva samples, respectively. This finding shows rapid detection of pLDH in patient saliva...
  10. pmc Confirmation of emergence of mutations associated with atovaquone-proguanil resistance in unexposed Plasmodium falciparum isolates from Africa
    Christian T Happi
    Malaria Research Laboratories, Institute for Advanced Medical Research and Training, College of Medicine, University of Ibadan, Nigeria
    Malar J 5:82. 2006
    ..However, little is known about the prevalence of codon-268 mutations in natural populations of P. falciparum without previous exposure to the drug in Africa...
  11. ncbi request reprint Dihydroartemisinin suppository in moderately severe malaria: comparative efficacy of dihydroartemisinin suppository versus intramuscular artemeter followed by oral sulfadoxine-pyrimethamine in the management of moderately severe malaria in Nigerian childr
    Catherine O Falade
    Malaria Research Laboratories, IMRAT, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Am J Trop Med Hyg 76:1-6. 2007
    ..2% (25 of 26) versus 96.2% (25 of 26) and 91.7% (22 of 24) for children treated with DHA and ART, respectively. In conclusion, both treatment regimens were efficacious and well tolerated...
  12. pmc A simple cost-effective high performance liquid chromatographic assay of sulphadoxine in whole blood spotted on filter paper for field studies
    Grace O Gbotosho
    Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Malar J 8:238. 2009
    ..Efforts in this study were thus devoted to development and evaluation of a simple, cost-effective and sensitive method for quantification of sulphadoxine in small capillary samples of whole blood dried on filter paper...
  13. doi request reprint Efficacy of artemisinin combination therapy for the treatment of uncomplicated falciparum malaria in Nigerian children
    Olusola Ojurongbe
    Ladoke Akintola University of Technology, Osogbo, Nigeria
    J Infect Dev Ctries 7:975-82. 2013
    ..Constant monitoring of drug efficacy is an important tool in establishing rational antimalarial drug policies...
  14. pmc Interaction between rifampicin, amodiaquine and artemether in mice infected with chloroquine resistant Plasmodium berghei
    Joseph A Badejo
    Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Malar J 13:299. 2014
    ..Thus, the intrinsic anti-malarial activity of the combination of clinical doses of rifampicin with amodiaquine and artemether was evaluated in an animal model using Plasmodium berghei...
  15. doi request reprint Interaction between ciprofloxacin and chloroquine in mice infected with chloroquine resistant Plasmodium berghei: interaction between ciprofloxacin and chloroqune
    Grace Olusola Gbotosho
    Department of Pharmacology and Therapeutics, College of Medicine, University of Ibadan, Ibadan, Nigeria
    Parasitol Res 110:895-9. 2012
    ..0002) compared with the other treatment groups. The results from this study support the potential usefulness of CFX in combination with antimalarial drugs for the treatment of chloroquine resistant human malaria...