Hirofumi Takada

Summary

Affiliation: Cancer Research UK
Country: UK

Publications

  1. ncbi [Cell surface protein Ecm33 is involved in negative feedback regulation of MAP kinase signalling and development of the in vivo real-time monitoring of MAP kinase signalling]
    Hirofumi Takada
    Laboratory of Molecular Pharmacogenomics, School of Pharmaceutical Sciences, Kinki University, Osaka, Japan
    Yakugaku Zasshi 131:1195-200. 2011
  2. pmc The cell surface protein gene ecm33+ is a target of the two transcription factors Atf1 and Mbx1 and negatively regulates Pmk1 MAPK cell integrity signaling in fission yeast
    Hirofumi Takada
    Laboratory of Molecular Pharmacogenomics, Laboratory of Molecular and Cellular Biology, and Laboratory of Bioinformatics, School of Pharmaceutical Sciences, Kinki University, Higashi Osaka, 577 8502, Japan
    Mol Biol Cell 21:674-85. 2010
  3. pmc Role of the RNA-binding protein Nrd1 and Pmk1 mitogen-activated protein kinase in the regulation of myosin mRNA stability in fission yeast
    Ryosuke Satoh
    Laboratory of Molecular Pharmacogenomics, and Laboratory of Pharmaceutical Analytical Chemistry, School of Pharmaceutical Sciences, Kinki University, Higashi Osaka 577 8502, Japan
    Mol Biol Cell 20:2473-85. 2009
  4. doi Acremomannolipin A, the potential calcium signal modulator with a characteristic glycolipid structure from the filamentous fungus Acremonium strictum
    Reiko Sugiura
    Laboratory of Molecular Pharmacogenomics, School of Pharmacy, Kinki University, 3 4 1 Kowakae, Higashi Osaka, Osaka 577 8502, Japan
    Bioorg Med Chem Lett 22:6735-9. 2012
  5. pmc Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast
    Hirofumi Takada
    Laboratory of Molecular Pharmacogenomics, School of Pharmaceutical Sciences, Kinki University, Higashi Osaka, 577 8502, Japan
    Mol Biol Cell 18:4794-802. 2007

Collaborators

Detail Information

Publications5

  1. ncbi [Cell surface protein Ecm33 is involved in negative feedback regulation of MAP kinase signalling and development of the in vivo real-time monitoring of MAP kinase signalling]
    Hirofumi Takada
    Laboratory of Molecular Pharmacogenomics, School of Pharmaceutical Sciences, Kinki University, Osaka, Japan
    Yakugaku Zasshi 131:1195-200. 2011
    ..In addition, the Ecm33 overproducing cells displayed phenotypes closely similar to those of the pmk1 knockout cell. Collectively, Ecm33 plays a role in the negative feedback regulation of Pmk1 cell integrity signaling...
  2. pmc The cell surface protein gene ecm33+ is a target of the two transcription factors Atf1 and Mbx1 and negatively regulates Pmk1 MAPK cell integrity signaling in fission yeast
    Hirofumi Takada
    Laboratory of Molecular Pharmacogenomics, Laboratory of Molecular and Cellular Biology, and Laboratory of Bioinformatics, School of Pharmaceutical Sciences, Kinki University, Higashi Osaka, 577 8502, Japan
    Mol Biol Cell 21:674-85. 2010
    ..Our results suggest that Ecm33 is involved in the negative feedback regulation of Pmk1 cell integrity signaling and is linked to cellular Ca(2+) signaling...
  3. pmc Role of the RNA-binding protein Nrd1 and Pmk1 mitogen-activated protein kinase in the regulation of myosin mRNA stability in fission yeast
    Ryosuke Satoh
    Laboratory of Molecular Pharmacogenomics, and Laboratory of Pharmaceutical Analytical Chemistry, School of Pharmaceutical Sciences, Kinki University, Higashi Osaka 577 8502, Japan
    Mol Biol Cell 20:2473-85. 2009
    ..Together, our results indicate that Nrd1 plays a role in the regulation of Cdc4 mRNA stability; moreover, our study is the first to demonstrate the posttranscriptional regulation of myosin expression by MAPK signaling...
  4. doi Acremomannolipin A, the potential calcium signal modulator with a characteristic glycolipid structure from the filamentous fungus Acremonium strictum
    Reiko Sugiura
    Laboratory of Molecular Pharmacogenomics, School of Pharmacy, Kinki University, 3 4 1 Kowakae, Higashi Osaka, Osaka 577 8502, Japan
    Bioorg Med Chem Lett 22:6735-9. 2012
    ..The activity was so potent as to exert the effect at a concentration of 200 nM...
  5. pmc Atf1 is a target of the mitogen-activated protein kinase Pmk1 and regulates cell integrity in fission yeast
    Hirofumi Takada
    Laboratory of Molecular Pharmacogenomics, School of Pharmaceutical Sciences, Kinki University, Higashi Osaka, 577 8502, Japan
    Mol Biol Cell 18:4794-802. 2007
    ..Together, our results suggest that PP2C is involved in a negative feedback loop of the Pmk1 signaling, and results also demonstrate that Atf1 is a key component of the cell integrity signaling downstream of Pmk1 MAPK...