Jerry Chan

Summary

Affiliation: Imperial College
Country: UK

Publications

  1. ncbi request reprint Human fetal mesenchymal stem cells as vehicles for gene delivery
    Jerry Chan
    Institute of Reproductive and Developmental Biology and Queen Charlote s and Chelsea Hospital, Imperial College London, Du Cane Road, London W12 0NN, UK
    Stem Cells 23:93-102. 2005
  2. ncbi request reprint Pragmatic comparison of beta2-agonist side effects within the Worldwide Atosiban versus Beta Agonists study
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London and Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    Eur J Obstet Gynecol Reprod Biol 128:135-41. 2006
  3. ncbi request reprint Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse
    Jerry Chan
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, London, United Kingdom
    Stem Cells 25:875-84. 2007
  4. doi request reprint First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Hum Reprod 23:2427-37. 2008
  5. ncbi request reprint Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, United Kingdom
    Stem Cells 24:1879-91. 2006
  6. ncbi request reprint Human fetal mesenchymal stem cells
    Keelin O'Donoghue
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, and Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Hammersmith Hospital Campus, London, UK
    Curr Stem Cell Res Ther 1:371-86. 2006
  7. ncbi request reprint Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype
    Nigel L Kennea
    Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, London, UK
    Cell Cycle 8:1069-79. 2009
  8. ncbi request reprint Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice
    Pascale V Guillot
    Institute of Reproductive and Developmental Biology, Imperial College, Hammersmith Campus, London, United Kingdom
    Blood 111:1717-25. 2008
  9. ncbi request reprint Osterix induces osteogenic gene expression but not differentiation in primary human fetal mesenchymal stem cells
    Hitoshi Kurata
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, UK
    Tissue Eng 13:1513-23. 2007
  10. ncbi request reprint Microchimerism in female bone marrow and bone decades after fetal mesenchymal stem-cell trafficking in pregnancy
    Keelin O'Donoghue
    Institute of Reproductive and Developmental Biology, Division of Paediatrics, Obstetrics and Gynaecology, Imperial College London, Hammersmith Campus, London W12 0NN, UK
    Lancet 364:179-82. 2004

Detail Information

Publications14

  1. ncbi request reprint Human fetal mesenchymal stem cells as vehicles for gene delivery
    Jerry Chan
    Institute of Reproductive and Developmental Biology and Queen Charlote s and Chelsea Hospital, Imperial College London, Du Cane Road, London W12 0NN, UK
    Stem Cells 23:93-102. 2005
    ..These results suggest that hfMSCs may be suitable targets for ex vivo genetic manipulation with onco-retroviral or lentiviral vectors without affecting their stem cell properties...
  2. ncbi request reprint Pragmatic comparison of beta2-agonist side effects within the Worldwide Atosiban versus Beta Agonists study
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London and Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, London, United Kingdom
    Eur J Obstet Gynecol Reprod Biol 128:135-41. 2006
    ..We aimed to compare side effect profiles of beta2-agonist tocolytics...
  3. ncbi request reprint Widespread distribution and muscle differentiation of human fetal mesenchymal stem cells after intrauterine transplantation in dystrophic mdx mouse
    Jerry Chan
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, London, United Kingdom
    Stem Cells 25:875-84. 2007
    ..Although the low-level of chimerism achieved is not curative for DMD, this approach may be useful in other severe mesenchymal or enzyme deficiency syndromes, where low-level protein expression may ameliorate disease pathology...
  4. doi request reprint First trimester embryo-fetoscopic and ultrasound-guided fetal blood sampling for ex vivo viral transduction of cultured human fetal mesenchymal stem cells
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
    Hum Reprod 23:2427-37. 2008
    ..We investigated the feasibility of harvesting circulating first trimester human fetal mesenchymal stem cells (hfMSCs) for ex vivo gene therapy...
  5. ncbi request reprint Galectin-1 induces skeletal muscle differentiation in human fetal mesenchymal stem cells and increases muscle regeneration
    Jerry Chan
    Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, United Kingdom
    Stem Cells 24:1879-91. 2006
    ..The high degree of myogenic conversion achieved by this method has relevance for the development of therapies for muscular dystrophies...
  6. ncbi request reprint Human fetal mesenchymal stem cells
    Keelin O'Donoghue
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, and Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Hammersmith Hospital Campus, London, UK
    Curr Stem Cell Res Ther 1:371-86. 2006
    ..The implications of hfMSC trafficking in pregnancy will be explored and the potential clinical applications of hfMSC in prenatal diagnosis and fetal therapy discussed...
  7. ncbi request reprint Differentiation of human fetal mesenchymal stem cells into cells with an oligodendrocyte phenotype
    Nigel L Kennea
    Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, London, UK
    Cell Cycle 8:1069-79. 2009
    ..Importantly, the process of in vivo differentiation occurred without cell fusion. These findings suggest that hfMSC may provide a potential source of oligodendrocytes for study and potential therapy...
  8. ncbi request reprint Intrauterine transplantation of human fetal mesenchymal stem cells from first-trimester blood repairs bone and reduces fractures in osteogenesis imperfecta mice
    Pascale V Guillot
    Institute of Reproductive and Developmental Biology, Imperial College, Hammersmith Campus, London, United Kingdom
    Blood 111:1717-25. 2008
    ....
  9. ncbi request reprint Osterix induces osteogenic gene expression but not differentiation in primary human fetal mesenchymal stem cells
    Hitoshi Kurata
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, UK
    Tissue Eng 13:1513-23. 2007
    ..In conclusion, Osx regulates osteogenic gene expression in hfMSCs but is insufficient to induce terminal osteogenic differentiation...
  10. ncbi request reprint Microchimerism in female bone marrow and bone decades after fetal mesenchymal stem-cell trafficking in pregnancy
    Keelin O'Donoghue
    Institute of Reproductive and Developmental Biology, Division of Paediatrics, Obstetrics and Gynaecology, Imperial College London, Hammersmith Campus, London W12 0NN, UK
    Lancet 364:179-82. 2004
    ..This finding has implications for normal pregnancy, for obstetric complications that increase fetomaternal trafficking, and for graft survival after transplantation...
  11. ncbi request reprint Human first-trimester fetal MSC express pluripotency markers and grow faster and have longer telomeres than adult MSC
    Pascale V Guillot
    Experimental Fetal Medicine Group, Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, Du Cane Road, London W12 0NN, U K
    Stem Cells 25:646-54. 2007
    ..01). Compared with adult MSC, first-trimester fetal tissues constitute a source of MSC with characteristics that appear advantageous for cell therapy...
  12. ncbi request reprint The case for tocolysis in threatened preterm labour
    Nicholas M Fisk
    Institute of Reproductive and Developmental Biology, Faculty of Medicine, Imperial College London, and Centre for Fetal Care, Queen Charlotte s and Chelsea Hospital, Hammersmith, London, UK
    BJOG 110:98-102. 2003
    ..Development of tocolytics that are safe for mother and baby should facilitate adequately-powered placebo-controlled studies, which both focus on women most likely to benefit and capitalise on the 1-7 days gained...
  13. ncbi request reprint Murine but not human mesenchymal stem cells generate osteosarcoma-like lesions in the lung
    Susana Aguilar
    Hematopoietic Stem Cell Laboratory, London Research Institute, Cancer Research UK, 44 Lincoln s Inn Fields, London WC2A 3PX, UK
    Stem Cells 25:1586-94. 2007
    ..These findings might be clinically relevant for future stem cell therapy studies. Disclosure of potential conflicts of interest is found at the end of this article...
  14. ncbi request reprint Placental mesenchymal stem cells
    Jerry Chan
    Am J Obstet Gynecol 196:e18; author reply e18-9. 2007