Genomes and Genes
Affiliation: King's College London
- glaikit is essential for the formation of epithelial polarity and neuronal developmentJohn Dunlop
Medical Research Council, Centre for Developmental Neurobiology, 4th Floor, New Hunts House, Guys Campus, King s College London, London SE1 1UL, United Kingdom
Curr Biol 14:2039-45. 2004..A mutation in the human homolog of gkt causes the neurodegenerative disease spinocerebellar ataxia with neuropathy (SCAN1), making it possible that a failure of membrane protein localization is a cause of this disease...
- Role of the GLT-1 subtype of glutamate transporter in glutamate homeostasis: the GLT-1-preferring inhibitor WAY-855 produces marginal neurotoxicity in the rat hippocampusJulie V Selkirk
Neurosciences Department, Neurocrine Biosciences Inc, 12970 El Camino Real, San Diego, CA 92130, USA
Eur J Neurosci 21:3217-28. 2005....
- Pituitary adenylate cyclase-activating peptide (PACAP) induces differentiation in the neuronal F11 cell line through a PKA-dependent pathwayH Beal McIlvain
Discovery Neuroscience, Wyeth Research, CN 8000 Princeton, NJ 08543, USA
Brain Res 1077:16-23. 2006..PACAP is upregulated in DRG neurons as a result of injury, and F11 cells provide an easily accessible in vitro model for understanding mechanisms underlying PACAP differentiation and neurogenesis...
- Direct inhibition of Ih by analgesic loperamide in rat DRG neuronsDmitry V Vasilyev
Discovery Neuroscience, Wyeth Research, CN 8000, Princeton, NJ 08543 8000, USA
J Neurophysiol 97:3713-21. 2007..Because I(h) channels are involved in pain processing, loperamide-induced inhibition of I(h) channels could provide an additional molecular mechanism for its analgesic action...