Maria Pufulete

Summary

Affiliation: King's College London
Country: UK

Publications

  1. ncbi request reprint Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study
    Maria Pufulete
    Nutrition Food and Health Research Centre, Department of Nutrition and Dietetics, King s College London, United Kingdom
    Gastroenterology 124:1240-8. 2003
  2. ncbi request reprint Folate, DNA methylation and colo-rectal cancer
    Maria Pufulete
    Nutrition Food and Health Research Centre, King s College London, 150 Stamford Street, London SE1 9NN, UK
    Proc Nutr Soc 62:437-45. 2003
  3. pmc Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer
    M Pufulete
    Nutritional Sciences Research Division, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
    Br J Cancer 92:838-42. 2005
  4. pmc Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma
    M Pufulete
    Nitritional Sciences Research Division, Department of Nutrition and Dietetics, King s College London, Franklin Wilkins Building, 150 Stamford St, London SE1 9NH, UK
    Gut 54:648-53. 2005
  5. doi request reprint Intake of dairy products and risk of colorectal neoplasia
    Maria Pufulete
    Diet and Gastrointestinal Health Group, Nutritional Sciences Division, King s College London, London, UK
    Nutr Res Rev 21:56-67. 2008
  6. doi request reprint The relationship between gene-specific DNA methylation in leukocytes and normal colorectal mucosa in subjects with and without colorectal tumors
    Mina Sarah Ally
    Diet and Gastrointestinal Health Group, Department of Nutrition and Dietetics, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, United Kingdom
    Cancer Epidemiol Biomarkers Prev 18:922-8. 2009
  7. ncbi request reprint Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia
    Reyad Al-Ghnaniem
    Nutritional Sciences Research Division, King s College London, London, United Kingdom
    Am J Clin Nutr 86:1064-72. 2007
  8. doi request reprint Short-term folate supplementation in physiological doses has no effect on ESR1 and MLH1 methylation in colonic mucosa of individuals with adenoma
    Reyad Al-Ghnaniem Abbadi
    Diabetes and Nutritional Sciences Division, King s College London, London, UK
    J Nutrigenet Nutrigenomics 5:327-38. 2012
  9. pmc The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia
    Joanna Hanks
    Diabetes and Nutritional Sciences Division, King s College London, London, United Kingdom J Hanks, IA, NK, AG, CLL, PE, and MP, and the Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom CR, J Harris, and MP
    Am J Clin Nutr 98:1564-74. 2013
  10. doi request reprint The influence of folate supplementation on global gene expression in normal colonic mucosa of subjects with colorectal adenoma
    Maria Pufulete
    Diabetes and Nutritional Sciences Division, King s College London, London, UK
    Mol Nutr Food Res 57:709-20. 2013

Collaborators

  • Michael Nelson
  • Jane Thomas
  • Kevin Whelan
  • Tom A B Sanders
  • Reyad Al-Ghnaniem
  • Joanna Hanks
  • Peter Emery
  • Reyad Al-Ghnaniem Abbadi
  • Matilda Owusu
  • Mina Sarah Ally
  • Chee Ling Liu
  • Jessica Harris
  • Chris Rogers
  • Alina Gheorghiu
  • Iyeman Ayed
  • Neil Kukreja
  • Edwin Wiredu
  • Jennifer Peters
  • Nigel Heaton
  • Roberta Foresti

Detail Information

Publications13

  1. ncbi request reprint Folate status, genomic DNA hypomethylation, and risk of colorectal adenoma and cancer: a case control study
    Maria Pufulete
    Nutrition Food and Health Research Centre, Department of Nutrition and Dietetics, King s College London, United Kingdom
    Gastroenterology 124:1240-8. 2003
    ....
  2. ncbi request reprint Folate, DNA methylation and colo-rectal cancer
    Maria Pufulete
    Nutrition Food and Health Research Centre, King s College London, 150 Stamford Street, London SE1 9NN, UK
    Proc Nutr Soc 62:437-45. 2003
    ..05) and colonic mucosa (P = 0.09). Further studies are required to confirm these findings in larger populations and to define abnormal ranges of DNA methylation...
  3. pmc Influence of folate status on genomic DNA methylation in colonic mucosa of subjects without colorectal adenoma or cancer
    M Pufulete
    Nutritional Sciences Research Division, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, UK
    Br J Cancer 92:838-42. 2005
    ..356, P=0.03). After adjusting for gender, age, body mass index, smoking and genotype, there were weak negative associations between serum and erythrocyte folate and colonic DNA hypomethylation (P=0.07 and P=0.08, respectively)...
  4. pmc Effect of folic acid supplementation on genomic DNA methylation in patients with colorectal adenoma
    M Pufulete
    Nitritional Sciences Research Division, Department of Nutrition and Dietetics, King s College London, Franklin Wilkins Building, 150 Stamford St, London SE1 9NH, UK
    Gut 54:648-53. 2005
    ....
  5. doi request reprint Intake of dairy products and risk of colorectal neoplasia
    Maria Pufulete
    Diet and Gastrointestinal Health Group, Nutritional Sciences Division, King s College London, London, UK
    Nutr Res Rev 21:56-67. 2008
    ..An outline of the proposed mechanisms responsible for the protective effect of both Ca and other potential chemopreventive components in dairy products will also be presented...
  6. doi request reprint The relationship between gene-specific DNA methylation in leukocytes and normal colorectal mucosa in subjects with and without colorectal tumors
    Mina Sarah Ally
    Diet and Gastrointestinal Health Group, Department of Nutrition and Dietetics, King s College London, Franklin Wilkins Building, 150 Stamford Street, London SE1 9NH, United Kingdom
    Cancer Epidemiol Biomarkers Prev 18:922-8. 2009
    ..However, unlike in colonic tissue, estrogen receptor alpha methylation in leukocytes was unable to distinguish between disease groups...
  7. ncbi request reprint Methylation of estrogen receptor alpha and mutL homolog 1 in normal colonic mucosa: association with folate and vitamin B-12 status in subjects with and without colorectal neoplasia
    Reyad Al-Ghnaniem
    Nutritional Sciences Research Division, King s College London, London, United Kingdom
    Am J Clin Nutr 86:1064-72. 2007
    ..Greater promoter methylation in some tumor-suppressor genes underlies most sporadic colorectal cancers and increases with age in the colon...
  8. doi request reprint Short-term folate supplementation in physiological doses has no effect on ESR1 and MLH1 methylation in colonic mucosa of individuals with adenoma
    Reyad Al-Ghnaniem Abbadi
    Diabetes and Nutritional Sciences Division, King s College London, London, UK
    J Nutrigenet Nutrigenomics 5:327-38. 2012
    ..We determined whether supplementation with physiological doses of folate could alter methylation in the oestrogen receptor 1 (ESR1) and mutL homolog 1 (MLH1) genes in colonic mucosa of subjects with colorectal adenoma...
  9. pmc The association between MTHFR 677C>T genotype and folate status and genomic and gene-specific DNA methylation in the colon of individuals without colorectal neoplasia
    Joanna Hanks
    Diabetes and Nutritional Sciences Division, King s College London, London, United Kingdom J Hanks, IA, NK, AG, CLL, PE, and MP, and the Clinical Trials and Evaluation Unit, School of Clinical Sciences, University of Bristol, Bristol, United Kingdom CR, J Harris, and MP
    Am J Clin Nutr 98:1564-74. 2013
    ..Decreased genomic and increased gene-specific DNA methylation predispose to colorectal cancer. Dietary folate intake and the methylenetetrahydrofolate reductase polymorphism (MTHFR 677C>T) may influence risk by modifying DNA methylation...
  10. doi request reprint The influence of folate supplementation on global gene expression in normal colonic mucosa of subjects with colorectal adenoma
    Maria Pufulete
    Diabetes and Nutritional Sciences Division, King s College London, London, UK
    Mol Nutr Food Res 57:709-20. 2013
    ..We determined whether short-term supplementation with a physiological dose of folate alters global gene expression in the normal colonic mucosa of subjects with colorectal adenoma...
  11. doi request reprint Folate status of Ghanaian populations in London and Accra
    Matilda Owusu
    Nutritional Sciences Division, King s College London, 150 Stamford Street, London SE1 9NH, UK
    Br J Nutr 103:437-44. 2010
    ..001). Findings from the present study suggest that migration from Ghana to the UK results in improvement of biomarkers of folate status despite the fact that reported dietary intake of folate was apparently lower in subjects from London...
  12. ncbi request reprint Genetics and diet--gene interactions: involvement, confidence and knowledge of dietitians
    Kevin Whelan
    Nutritional Sciences Division, King s College London, 150 Stamford Street, London SE1 9NH, UK
    Br J Nutr 99:23-8. 2008
    ....
  13. ncbi request reprint Validation of a short food frequency questionnaire to assess folate intake
    Maria Pufulete
    Nutrition, Food and Health Research Centre, King s College London, UK
    Br J Nutr 87:383-90. 2002
    ..Overall, these results suggest that this short FFQ is a useful method for assessing folate intake, particularly in men...