M Carrington

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Selective metabolic labelling of intracellular parasite proteins using ricin
    M Carrington
    Department of Biochemistry, Tennis Court Road, Cambridge, UK
    Parasitol Today 12:492-5. 1996
  2. ncbi request reprint Implications of conserved structural motifs in disparate trypanosome surface proteins
    M Carrington
    University of Cambridge, Department of Biochemistry, UK
    Mol Biochem Parasitol 81:119-26. 1996
  3. ncbi request reprint The properties and function of the glycosylphosphatidylinositol-phospholipase C in Trypanosoma brucei
    M Carrington
    Department of Biochemistry, Cambridge, UK
    Mol Biochem Parasitol 91:153-64. 1998
  4. ncbi request reprint Conservation of genetic linkage between heat shock protein 100 and glycosylphosphatidylinositol-specific phospholipase C in Trypanosoma brucei and Trypanosoma cruzi
    M B Redpath
    Department of Biochemistry, University of Cambridge, UK
    Mol Biochem Parasitol 94:113-21. 1998
  5. ncbi request reprint ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei
    M B Redpath
    Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK
    Mol Biochem Parasitol 111:223-8. 2000
  6. pmc Identification of the C-terminal region of 70 kDa heat shock protein from Leishmania (Viannia) braziliensis as a target for the humoral immune response
    A G Amorim
    Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Brazil
    Cell Stress Chaperones 1:177-87. 1996
  7. ncbi request reprint Lessons learned from the emergence of a new Trypanosoma brucei rhodesiense sleeping sickness focus in Uganda
    O C Hutchinson
    Department of Biochemistry, University of Cambridge, Cambridge, UK
    Lancet Infect Dis 3:42-5. 2003
  8. doi request reprint Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage
    S E Hiby
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Hum Reprod 23:972-6. 2008
  9. ncbi request reprint A distinct cyclin A is expressed in germ cells in the mouse
    C Sweeney
    University of Cambridge, Department of Biochemistry, UK
    Development 122:53-64. 1996
  10. ncbi request reprint The coatomer of Trypanosoma brucei
    A G Maier
    Zentrum für Molekulare Biologie ZMBH, Im Nevenheimer Feld 282, 69120, Heidelberg, Germany
    Mol Biochem Parasitol 115:55-61. 2001

Collaborators

  • S C Welburn
  • E Pays
  • L Regan
  • A Moffett
  • Pauline Ward
  • M Berriman
  • Susan Gottesman
  • M B Redpath
  • S E Hiby
  • J D Barry
  • O C Hutchinson
  • A G Maier
  • A G Amorim
  • H Webb
  • L Farrell
  • W Lo
  • N el-Sayed
  • N Jones
  • H Renauld
  • L J Morrison
  • L Marcello
  • C Hertz-Fowler
  • U Böhme
  • A F Read
  • G Blandin
  • E Caler
  • K Lythgoe
  • E M Fèvre
  • C Sweeney
  • M Bremser
  • M Ding
  • C Clayton
  • H Windle
  • H P Voorheis
  • D Nolan
  • M L Guther
  • A Amorim
  • N Carnall
  • M Courel
  • M L Cardoso De Almeida
  • M A Miles
  • S E Ravnik
  • M Murphy
  • M Kubelka
  • C F Hawkins
  • M L de Almeida
  • D C Barker
  • D J Wolgemuth
  • H Riezman
  • L F Zerbini
  • M L Cardoso-de-Almeida
  • D P Morga
  • V S Piestun
  • B A Castilho-Valavicius

Detail Information

Publications13

  1. ncbi request reprint Selective metabolic labelling of intracellular parasite proteins using ricin
    M Carrington
    Department of Biochemistry, Tennis Court Road, Cambridge, UK
    Parasitol Today 12:492-5. 1996
    ..Here, Mark Carrington, Yael Shochat and Anne Gurnett describe a method for overcoming this problem through the use of the toxin ricin to inhibit host cell protein synthesis specifically...
  2. ncbi request reprint Implications of conserved structural motifs in disparate trypanosome surface proteins
    M Carrington
    University of Cambridge, Department of Biochemistry, UK
    Mol Biochem Parasitol 81:119-26. 1996
    ..These findings suggest that this master structure has evolved to facilitate a range of functions and has implications for understanding the architecture of the trypanosome cell surface and the origins of antigenic variation...
  3. ncbi request reprint The properties and function of the glycosylphosphatidylinositol-phospholipase C in Trypanosoma brucei
    M Carrington
    Department of Biochemistry, Cambridge, UK
    Mol Biochem Parasitol 91:153-64. 1998
    ..The phenotype indicates that the gene is non-essential, but its absence alters the course of infection in mice...
  4. ncbi request reprint Conservation of genetic linkage between heat shock protein 100 and glycosylphosphatidylinositol-specific phospholipase C in Trypanosoma brucei and Trypanosoma cruzi
    M B Redpath
    Department of Biochemistry, University of Cambridge, UK
    Mol Biochem Parasitol 94:113-21. 1998
    ..Thus, the hsp100 and gpi-plc genes are adjacent in T. brucei and this linkage is conserved in T. cruzi. This observation has been used to facilitate the isolation of a clone encoding a T. cruzi phospholipase C gene...
  5. ncbi request reprint ESAG11, a new VSG expression site-associated gene from Trypanosoma brucei
    M B Redpath
    Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge, CB2 1GA, UK
    Mol Biochem Parasitol 111:223-8. 2000
  6. pmc Identification of the C-terminal region of 70 kDa heat shock protein from Leishmania (Viannia) braziliensis as a target for the humoral immune response
    A G Amorim
    Universidade Federal de Sao Paulo, Escola Paulista de Medicina, Brazil
    Cell Stress Chaperones 1:177-87. 1996
    ..amazonensis-infected individuals. Despite a relatively high cross-reactivity with VL sera, the enhanced humoral response of MCL as compared with CL patients might be interesting for studies on disease aggravation...
  7. ncbi request reprint Lessons learned from the emergence of a new Trypanosoma brucei rhodesiense sleeping sickness focus in Uganda
    O C Hutchinson
    Department of Biochemistry, University of Cambridge, Cambridge, UK
    Lancet Infect Dis 3:42-5. 2003
    ....
  8. doi request reprint Association of maternal killer-cell immunoglobulin-like receptors and parental HLA-C genotypes with recurrent miscarriage
    S E Hiby
    Department of Pathology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QP, UK
    Hum Reprod 23:972-6. 2008
    ..Pre-eclampsia and recurrent miscarriage (RM) share the pathogenesis of defective placentation and therefore we have now genotyped couples with RM...
  9. ncbi request reprint A distinct cyclin A is expressed in germ cells in the mouse
    C Sweeney
    University of Cambridge, Department of Biochemistry, UK
    Development 122:53-64. 1996
    ..These data indicate that mammalian germ cells contain cyclin A1-dependent kinases that either act as a substitute for, or in addition to, the cyclin A2-dependent kinases characterised in somatic tissues...
  10. ncbi request reprint The coatomer of Trypanosoma brucei
    A G Maier
    Zentrum für Molekulare Biologie ZMBH, Im Nevenheimer Feld 282, 69120, Heidelberg, Germany
    Mol Biochem Parasitol 115:55-61. 2001
    ..The trypanosome coatomer complex was partially purified using a procedure similar to that used for bovine coatomer...
  11. ncbi request reprint Expression of Mycobacterium leprae 18-kDa antigen in yeast in a GPI-anchored form
    A G Amorim
    Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, , Brasil
    Braz J Med Biol Res 27:623-6. 1994
    ..The non-transformed cells are negative. These data indicate that our system may be suitable for the expression of foreign proteins in yeast in a GPI-anchored form...
  12. ncbi request reprint What the genome sequence is revealing about trypanosome antigenic variation
    J D Barry
    University of Glasgow, Glasgow G12 8QQ, Scotland, UK
    Biochem Soc Trans 33:986-9. 2005
    ..These findings from the genome project have major implications for evolution of the VSG archive and for transmission of the parasite in the field...
  13. pmc Conservation of the regulatory subunit for the Clp ATP-dependent protease in prokaryotes and eukaryotes
    S Gottesman
    National Cancer Institute, Laboratory of Molecular Biology, Bethesda, MD 20892
    Proc Natl Acad Sci U S A 87:3513-7. 1990
    ..The high degree of similarity among the ClpA-like proteins suggests that Clp-like proteases are likely to be important participants in energy-dependent proteolysis in prokaryotic and eukaryotic cells...