Helen J Cooper
Affiliation: University of Birmingham
- Cooper H, Tatham M, Jaffray E, Heath J, Lam T, Marshall A, et al. Fourier transform ion cyclotron resonance mass spectrometry for the analysis of small ubiquitin-like modifier (SUMO) modification: identification of lysines in RanBP2 and SUMO targeted for modification during the E3 autoSUMOylation reaction. Anal Chem. 2005;77:6310-9 pubmed....
- Powell T, Bowra S, Cooper H. Subcritical Water Hydrolysis of Peptides: Amino Acid Side-Chain Modifications. J Am Soc Mass Spectrom. 2017;: pubmed publisher..In the absence of cysteine and methionine, oxidation of tryptophan was observed. In addition, water loss from aspartic acid and C-terminal amidation were observed in harsher subcritical water conditions. Graphical Abstract ᅟ. ..
- Kocurek K, Stones L, Bunch J, May R, Cooper H. Top-Down LESA Mass Spectrometry Protein Analysis of Gram-Positive and Gram-Negative Bacteria. J Am Soc Mass Spectrom. 2017;28:2066-2077 pubmed publisher..The potential of LESA MS for classification and characterization of novel species is illustrated by the de novo sequencing of a new protein from the unknown species of Staphylococcus. Graphical Abstract ᅟ. ..
- Griffiths R, Kocurek K, Cooper H. Ambient surface mass spectrometry-ion mobility spectrometry of intact proteins. Curr Opin Chem Biol. 2017;42:67-75 pubmed publisher..In this review, we discuss the application of ambient mass spectrometry and ion mobility spectrometry to the analysis of intact proteins, and discuss opportunities and challenges for the field...