Neil G Harris
Affiliation: University of Cambridge
- MRI measurement of blood-brain barrier permeability following spontaneous reperfusion in the starch microsphere model of ischemiaNeil G Harris
Unit of Biophysics, Institute of Child Health, University of London, London, United Kingdom
Magn Reson Imaging 20:221-30. 2002..Differences between Gd-DTPA-enhancement and HRP may reflect differences in the molecular size of the tracers...
- (18)F-Endothelin-1, a positron emission tomography (PET) radioligand for the endothelin receptor system: radiosynthesis and in vivo imaging using microPETPeter Johnström
Clinical Pharmacology Unit, University of Cambridge, Level 6, Centre for Clinical Investigation, Box 110, Addenbrooke s Hospital, Cambridge CB2 2QQ, U K
Clin Sci (Lond) 103:4S-8S. 2002..The resolution of the microPET scanner was sufficient to differentiate heterogeneous uptake in subrenal structures in the rat...
- Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivoPeter Johnström
Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Br J Pharmacol 144:115-22. 2005..Under conditions of ET(B) receptor blockade, the heart could be visualised by microPET imaging.These results suggest that clearance by ET(B) receptors in the lung and kidney prevents binding of ET-1 to receptors in the heart...
- Temporal relation between the ADC and DC potential responses to transient focal ischemia in the rat: a Markov chain Monte Carlo simulation analysisMartin D King
RCS Unit of Biophysics, Institute of Child Health, University College, London, UK
J Cereb Blood Flow Metab 23:677-88. 2003..This work demonstrates a general analytical approach to the multivariate, longitudinal data-processing problem that commonly arises in stroke and other biomedical research...
- Neuroimaging of animal models of brain diseaseMark F Lythgoe
RCS Unit of Biophysics, Institute of Child Health, University College London, UK
Br Med Bull 65:235-57. 2003..It is important, therefore, to understand the various types of animal model available and choose an appropriate model for the research question...
- Normal pressure hydrocephalus and cerebral blood flow: a PET study of baseline valuesBrian K Owler
Academic Neurosurgery Unit, Addenbrooke s Hospital, Cambridge, UK
J Cereb Blood Flow Metab 24:17-23. 2004..The results suggest that the role of the basal ganglia and thalamus in NPH may be more prominent than currently appreciated. The implications for theories regarding the pathogenesis of NPH are discussed...
- Changes in cerebral blood flow during cerebrospinal fluid pressure manipulation in patients with normal pressure hydrocephalus: a methodological studyBrian K Owler
Academic Neurosurgery Unit, Addenbrooke s Hospital, University of Cambridge, Cambridge, United Kingdom
J Cereb Blood Flow Metab 24:579-87. 2004....
- Relationship between flow-metabolism uncoupling and evolving axonal injury after experimental traumatic brain injurySzu Fu Chen
Academic Neurosurgery, Center for Brain Repair, University of Cambridge, Robinson Way, UK
J Cereb Blood Flow Metab 24:1025-36. 2004..Our study indicates a possible dependence of axonal outcome on flow-metabolism in the acute injury stage...
- Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injuryBrenda L Bartnik
Division of Neurosurgery, Department of Surgery, Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 92354, USA
J Neurotrauma 22:1052-65. 2005..5 and 24 h after a moderate to severe CCI injury...