Neil G Harris

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint MRI measurement of blood-brain barrier permeability following spontaneous reperfusion in the starch microsphere model of ischemia
    Neil G Harris
    Unit of Biophysics, Institute of Child Health, University of London, London, United Kingdom
    Magn Reson Imaging 20:221-30. 2002
  2. ncbi request reprint (18)F-Endothelin-1, a positron emission tomography (PET) radioligand for the endothelin receptor system: radiosynthesis and in vivo imaging using microPET
    Peter Johnström
    Clinical Pharmacology Unit, University of Cambridge, Level 6, Centre for Clinical Investigation, Box 110, Addenbrooke s Hospital, Cambridge CB2 2QQ, U K
    Clin Sci (Lond) 103:4S-8S. 2002
  3. pmc Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivo
    Peter Johnström
    Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Br J Pharmacol 144:115-22. 2005
  4. ncbi request reprint Temporal relation between the ADC and DC potential responses to transient focal ischemia in the rat: a Markov chain Monte Carlo simulation analysis
    Martin D King
    RCS Unit of Biophysics, Institute of Child Health, University College, London, UK
    J Cereb Blood Flow Metab 23:677-88. 2003
  5. ncbi request reprint Neuroimaging of animal models of brain disease
    Mark F Lythgoe
    RCS Unit of Biophysics, Institute of Child Health, University College London, UK
    Br Med Bull 65:235-57. 2003
  6. ncbi request reprint Normal pressure hydrocephalus and cerebral blood flow: a PET study of baseline values
    Brian K Owler
    Academic Neurosurgery Unit, Addenbrooke s Hospital, Cambridge, UK
    J Cereb Blood Flow Metab 24:17-23. 2004
  7. ncbi request reprint Changes in cerebral blood flow during cerebrospinal fluid pressure manipulation in patients with normal pressure hydrocephalus: a methodological study
    Brian K Owler
    Academic Neurosurgery Unit, Addenbrooke s Hospital, University of Cambridge, Cambridge, United Kingdom
    J Cereb Blood Flow Metab 24:579-87. 2004
  8. ncbi request reprint Relationship between flow-metabolism uncoupling and evolving axonal injury after experimental traumatic brain injury
    Szu Fu Chen
    Academic Neurosurgery, Center for Brain Repair, University of Cambridge, Robinson Way, UK
    J Cereb Blood Flow Metab 24:1025-36. 2004
  9. ncbi request reprint Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury
    Brenda L Bartnik
    Division of Neurosurgery, Department of Surgery, Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 92354, USA
    J Neurotrauma 22:1052-65. 2005

Collaborators

Detail Information

Publications9

  1. ncbi request reprint MRI measurement of blood-brain barrier permeability following spontaneous reperfusion in the starch microsphere model of ischemia
    Neil G Harris
    Unit of Biophysics, Institute of Child Health, University of London, London, United Kingdom
    Magn Reson Imaging 20:221-30. 2002
    ..Differences between Gd-DTPA-enhancement and HRP may reflect differences in the molecular size of the tracers...
  2. ncbi request reprint (18)F-Endothelin-1, a positron emission tomography (PET) radioligand for the endothelin receptor system: radiosynthesis and in vivo imaging using microPET
    Peter Johnström
    Clinical Pharmacology Unit, University of Cambridge, Level 6, Centre for Clinical Investigation, Box 110, Addenbrooke s Hospital, Cambridge CB2 2QQ, U K
    Clin Sci (Lond) 103:4S-8S. 2002
    ..The resolution of the microPET scanner was sufficient to differentiate heterogeneous uptake in subrenal structures in the rat...
  3. pmc Positron emission tomography using 18F-labelled endothelin-1 reveals prevention of binding to cardiac receptors owing to tissue-specific clearance by ET B receptors in vivo
    Peter Johnström
    Clinical Pharmacology Unit, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Br J Pharmacol 144:115-22. 2005
    ..Under conditions of ET(B) receptor blockade, the heart could be visualised by microPET imaging.These results suggest that clearance by ET(B) receptors in the lung and kidney prevents binding of ET-1 to receptors in the heart...
  4. ncbi request reprint Temporal relation between the ADC and DC potential responses to transient focal ischemia in the rat: a Markov chain Monte Carlo simulation analysis
    Martin D King
    RCS Unit of Biophysics, Institute of Child Health, University College, London, UK
    J Cereb Blood Flow Metab 23:677-88. 2003
    ..This work demonstrates a general analytical approach to the multivariate, longitudinal data-processing problem that commonly arises in stroke and other biomedical research...
  5. ncbi request reprint Neuroimaging of animal models of brain disease
    Mark F Lythgoe
    RCS Unit of Biophysics, Institute of Child Health, University College London, UK
    Br Med Bull 65:235-57. 2003
    ..It is important, therefore, to understand the various types of animal model available and choose an appropriate model for the research question...
  6. ncbi request reprint Normal pressure hydrocephalus and cerebral blood flow: a PET study of baseline values
    Brian K Owler
    Academic Neurosurgery Unit, Addenbrooke s Hospital, Cambridge, UK
    J Cereb Blood Flow Metab 24:17-23. 2004
    ..The results suggest that the role of the basal ganglia and thalamus in NPH may be more prominent than currently appreciated. The implications for theories regarding the pathogenesis of NPH are discussed...
  7. ncbi request reprint Changes in cerebral blood flow during cerebrospinal fluid pressure manipulation in patients with normal pressure hydrocephalus: a methodological study
    Brian K Owler
    Academic Neurosurgery Unit, Addenbrooke s Hospital, University of Cambridge, Cambridge, United Kingdom
    J Cereb Blood Flow Metab 24:579-87. 2004
    ....
  8. ncbi request reprint Relationship between flow-metabolism uncoupling and evolving axonal injury after experimental traumatic brain injury
    Szu Fu Chen
    Academic Neurosurgery, Center for Brain Repair, University of Cambridge, Robinson Way, UK
    J Cereb Blood Flow Metab 24:1025-36. 2004
    ..Our study indicates a possible dependence of axonal outcome on flow-metabolism in the acute injury stage...
  9. ncbi request reprint Upregulation of pentose phosphate pathway and preservation of tricarboxylic acid cycle flux after experimental brain injury
    Brenda L Bartnik
    Division of Neurosurgery, Department of Surgery, Brain Injury Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 92354, USA
    J Neurotrauma 22:1052-65. 2005
    ..5 and 24 h after a moderate to severe CCI injury...