Wen Chang Li

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. ncbi request reprint Persistent responses to brief stimuli: feedback excitation among brainstem neurons
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Bristol BS8 1UG, United Kingdom
    J Neurosci 26:4026-35. 2006
  2. ncbi request reprint Spinal inhibitory neurons that modulate cutaneous sensory pathways during locomotion in a simple vertebrate
    W C Li
    School of Biological Sciences, University of Bristol, Bristol, BS8 1UG, United Kingdom
    J Neurosci 22:10924-34. 2002
  3. pmc Axon and dendrite geography predict the specificity of synaptic connections in a functioning spinal cord network
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK
    Neural Dev 2:17. 2007
  4. ncbi request reprint Primitive roles for inhibitory interneurons in developing frog spinal cord
    W C Li
    School of Biological Sciences, University of Bristol, Bristol BS8 1UG, United Kingdom
    J Neurosci 24:5840-8. 2004
  5. ncbi request reprint Dorsal spinal interneurons forming a primitive, cutaneous sensory pathway
    W C Li
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK
    J Neurophysiol 92:895-904. 2004
  6. ncbi request reprint A direct comparison of whole cell patch and sharp electrodes by simultaneous recording from single spinal neurons in frog tadpoles
    W C Li
    School of Biological Sciences, University of Bristol, Woodland Rd, Bristol BS8 1UG, UK
    J Neurophysiol 92:380-6. 2004
  7. ncbi request reprint The spinal interneurons and properties of glutamatergic synapses in a primitive vertebrate cutaneous flexion reflex
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Bristol, BS8 1UG, United Kingdom
    J Neurosci 23:9068-77. 2003
  8. pmc Defining the excitatory neurons that drive the locomotor rhythm in a simple vertebrate: insights into the origin of reticulospinal control
    Stephen R Soffe
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK
    J Physiol 587:4829-44. 2009
  9. pmc Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors
    Wen Chang Li
    School of Biology, University of St Andrews, St Andrews, Fife KY16 9TS, United Kingdom, and School of Biological Sciences, University of Bristol, Bristol BS81UG, United Kingdom
    J Neurosci 30:16609-20. 2010
  10. pmc The generation of antiphase oscillations and synchrony by a rebound-based vertebrate central pattern generator
    Wen Chang Li
    School of Psychology and Neuroscience, University of St Andrews, St Andrews, Fife, KY16 9TS, United Kingdom, School of Computing and Mathematics, Plymouth University, Plymouth, Devon, PL4 8AA, United Kingdom, and Institute of Mathematical Problems in Biology, Russian Academy of Sciences, 142290, Pushchino, Russia
    J Neurosci 34:6065-77. 2014

Detail Information

Publications15

  1. ncbi request reprint Persistent responses to brief stimuli: feedback excitation among brainstem neurons
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Bristol BS8 1UG, United Kingdom
    J Neurosci 26:4026-35. 2006
    ..Its presence in a lower brain region early in development suggests that it is a basic feature of neuronal network design...
  2. ncbi request reprint Spinal inhibitory neurons that modulate cutaneous sensory pathways during locomotion in a simple vertebrate
    W C Li
    School of Biological Sciences, University of Bristol, Bristol, BS8 1UG, United Kingdom
    J Neurosci 22:10924-34. 2002
    ..We conclude that ascending interneurons are a major class of modulatory neurons producing inhibitory gating of cutaneous sensory pathways during swimming and struggling...
  3. pmc Axon and dendrite geography predict the specificity of synaptic connections in a functioning spinal cord network
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK
    Neural Dev 2:17. 2007
    ..This is possible because detailed information is now available on the identity and synaptic connections of the main types of neuron...
  4. ncbi request reprint Primitive roles for inhibitory interneurons in developing frog spinal cord
    W C Li
    School of Biological Sciences, University of Bristol, Bristol BS8 1UG, United Kingdom
    J Neurosci 24:5840-8. 2004
    ....
  5. ncbi request reprint Dorsal spinal interneurons forming a primitive, cutaneous sensory pathway
    W C Li
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK
    J Neurophysiol 92:895-904. 2004
    ....
  6. ncbi request reprint A direct comparison of whole cell patch and sharp electrodes by simultaneous recording from single spinal neurons in frog tadpoles
    W C Li
    School of Biological Sciences, University of Bristol, Woodland Rd, Bristol BS8 1UG, UK
    J Neurophysiol 92:380-6. 2004
    ..We conclude that sharp electrodes introduce a significant leak to the membrane of tadpole spinal neurons compared with patch electrodes but that this does not change the fundamental firing characteristics or activity of the neurons...
  7. ncbi request reprint The spinal interneurons and properties of glutamatergic synapses in a primitive vertebrate cutaneous flexion reflex
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Bristol, BS8 1UG, United Kingdom
    J Neurosci 23:9068-77. 2003
    ..The distribution of glutamate receptors at synapses in this developing circuit is tuned so that synapses have properties suited to their roles in the whole animal's reflex responses...
  8. pmc Defining the excitatory neurons that drive the locomotor rhythm in a simple vertebrate: insights into the origin of reticulospinal control
    Stephen R Soffe
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol BS8 1UG, UK
    J Physiol 587:4829-44. 2009
    ..We discuss the origin of these reticulospinal neurons as specialised members of a longitudinally distributed population of excitatory interneurons extending from the brainstem into the spinal cord...
  9. pmc Specific brainstem neurons switch each other into pacemaker mode to drive movement by activating NMDA receptors
    Wen Chang Li
    School of Biology, University of St Andrews, St Andrews, Fife KY16 9TS, United Kingdom, and School of Biological Sciences, University of Bristol, Bristol BS81UG, United Kingdom
    J Neurosci 30:16609-20. 2010
    ..This allows rhythm generation in a half-CNS and raises the possibility that such concealed pacemaker properties may be present underlying rhythm generation in other vertebrate brain networks...
  10. pmc The generation of antiphase oscillations and synchrony by a rebound-based vertebrate central pattern generator
    Wen Chang Li
    School of Psychology and Neuroscience, University of St Andrews, St Andrews, Fife, KY16 9TS, United Kingdom, School of Computing and Mathematics, Plymouth University, Plymouth, Devon, PL4 8AA, United Kingdom, and Institute of Mathematical Problems in Biology, Russian Academy of Sciences, 142290, Pushchino, Russia
    J Neurosci 34:6065-77. 2014
    ..Modeling also shows that lengthening the time window between phasic excitation and inhibition by increasing dIN synaptic/conduction delay can improve the stability of synchrony. ..
  11. ncbi request reprint Reconfiguration of a vertebrate motor network: specific neuron recruitment and context-dependent synaptic plasticity
    Wen Chang Li
    School of Biological Sciences, University of Bristol, Bristol BS8 1UG, United Kingdom
    J Neurosci 27:12267-76. 2007
    ..This provides one possible mechanism for burst termination not seen in the swimming CPG. The direct demonstration of depression in reciprocal inhibition confirms a key element of Brown's (1911) hypothesis for locomotor rhythmogenesis...
  12. doi request reprint Roles for inhibition: studies on networks controlling swimming in young frog tadpoles
    Alan Roberts
    School of Biological Sciences, University of Bristol, Woodland Road, Bristol, BS8 1UG, UK
    J Comp Physiol A Neuroethol Sens Neural Behav Physiol 194:185-93. 2008
    ..They may also produce tonic inhibition while the tadpole is at rest that reduces spontaneous swimming and responsiveness of the tadpole, keeping it still so it is not noticed by predators...
  13. doi request reprint A functional scaffold of CNS neurons for the vertebrates: the developing Xenopus laevis spinal cord
    Alan Roberts
    Biological Sciences, University of Bristol, Woodland Road, Bristol, United Kingdom
    Dev Neurobiol 72:575-84. 2012
    ..Our present knowledge about the hatchling Xenopus spinal cord should set up many of the problems to be unraveled in the future by more developmentally oriented research...
  14. pmc How neurons generate behavior in a hatchling amphibian tadpole: an outline
    Alan Roberts
    School of Biological Sciences, University of Bristol, Bristol, UK
    Front Behav Neurosci 4:16. 2010
    ..Although much remains to be explained, study of this simple vertebrate has uncovered basic principles about the function and organization of vertebrate nervous systems...
  15. ncbi request reprint Role of type-specific neuron properties in a spinal cord motor network
    Bart Sautois
    Department of Applied Mathematics and Computer Science, Ghent University, Krijgslaan 281 S9, B 9000 Ghent, Belgium
    J Comput Neurosci 23:59-77. 2007
    ....