Neil A McEwan

Summary

Affiliation: University of Liverpool
Country: UK

Publications

  1. ncbi request reprint A comparison of adherence by four strains of Staphylococcus intermedius and Staphylococcus hominis to canine corneocytes collected from normal dogs and dogs suffering from atopic dermatitis
    N A McEwan
    Division of Companion Animals, Department of Verterinary Clinical Studies, Institute of Comparative Medicine, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH, UK
    Res Vet Sci 78:193-8. 2005
  2. ncbi request reprint Adherence by Staphylococcus intermedius to canine corneocytes: a preliminary study comparing noninflamed and inflamed atopic canine skin
    Neil A McEwan
    University of Liverpool, Small Animal Hospital, Crown Street, Liverpool, L7 7EX, UK
    Vet Dermatol 17:151-4. 2006
  3. ncbi request reprint Monosaccharide inhibition of adherence by Pseudomonas aeruginosa to canine corneocytes
    Neil A McEwan
    Faculty of Veterinary Science, Small Animal Teaching Hospital, The University of Liverpool, Leahurst, Chester High Road, Neston, Wirral CH64 7TE, UK
    Vet Dermatol 19:221-5. 2008
  4. doi request reprint Efficacy of a 0.0584% hydrocortisone aceponate spray in presumed feline allergic dermatitis: an open label pilot study
    Vanessa Schmidt
    School of Veterinary Science, The University of Liverpool, Leahurst, Cheshire CH64 7TE, UK
    Vet Dermatol 23:11-6, e3-4. 2012
  5. doi request reprint Staphylococcal colonization of mucosal and lesional skin sites in atopic and healthy dogs
    Jennifer Fazakerley
    Department of Veterinary Clinical Science, The University of Liverpool, Faculty of Veterinary Science, Liverpool, UK
    Vet Dermatol 20:179-84. 2009
  6. doi request reprint A two-dimensional morphological study of corneocytes from healthy dogs and cats and from dogs with atopic dermatitis
    Neil A McEwan
    Small Animal Teaching Hospital, The University of Liverpool, Leahurst Campus Neston, Wirral, UK
    Vet Dermatol 20:360-8. 2009
  7. doi request reprint Despite identifying some shared gene associations with human atopic dermatitis the use of multiple dog breeds from various locations limits detection of gene associations in canine atopic dermatitis
    Shona H Wood
    Department of Comparative Molecular Medicine, School of Veterinary Science, The University of Liverpool, Liverpool, UK
    Vet Immunol Immunopathol 138:193-7. 2010
  8. doi request reprint Reference genes for canine skin when using quantitative real-time PCR
    Shona H Wood
    Department of Veterinary Pathology, Faculty of Veterinary Science, University of Liverpool, Liverpool, UK
    Vet Immunol Immunopathol 126:392-5. 2008
  9. doi request reprint Gene expression in canine atopic dermatitis and correlation with clinical severity scores
    Shona H Wood
    Department of Veterinary Pathology, Faculty of Veterinary Science, University of Liverpool, Liverpool, UK
    J Dermatol Sci 55:27-33. 2009
  10. doi request reprint Tris-EDTA significantly enhances antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa in vitro
    Laura M Buckley
    School of Veterinary Science, The University of Liverpool, Leahurst Campus, Neston, Cheshire, CH64 7TE, UK
    Vet Dermatol 24:519-e122. 2013

Collaborators

  • Tim Nuttall
  • Dylan N Clements
  • Vanessa Schmidt
  • Shona H Wood
  • Stuart D Carter
  • William E Ollier
  • Laura M Buckley
  • Jennifer Fazakerley
  • Annemarie E Merryman-Simpson
  • Yi Fang Lu
  • Debby Sales
  • C Anthony Hart
  • Paul G Jones
  • William M McLaren
  • Neale Fretwell

Detail Information

Publications14

  1. ncbi request reprint A comparison of adherence by four strains of Staphylococcus intermedius and Staphylococcus hominis to canine corneocytes collected from normal dogs and dogs suffering from atopic dermatitis
    N A McEwan
    Division of Companion Animals, Department of Verterinary Clinical Studies, Institute of Comparative Medicine, University of Glasgow Veterinary School, Bearsden Road, Glasgow G61 1QH, UK
    Res Vet Sci 78:193-8. 2005
    ..It was concluded that the adherence assay employed here showed that S. hominis does not adhere to canine corneocytes, S. intermedius adheres preferentially to atopic corneocytes...
  2. ncbi request reprint Adherence by Staphylococcus intermedius to canine corneocytes: a preliminary study comparing noninflamed and inflamed atopic canine skin
    Neil A McEwan
    University of Liverpool, Small Animal Hospital, Crown Street, Liverpool, L7 7EX, UK
    Vet Dermatol 17:151-4. 2006
    ..This may be important in the colonization of atopic skin by this microorganism. Strain variation in the ability of S. intermedius to adhere to canine atopic corneocytes is probable...
  3. ncbi request reprint Monosaccharide inhibition of adherence by Pseudomonas aeruginosa to canine corneocytes
    Neil A McEwan
    Faculty of Veterinary Science, Small Animal Teaching Hospital, The University of Liverpool, Leahurst, Chester High Road, Neston, Wirral CH64 7TE, UK
    Vet Dermatol 19:221-5. 2008
    ..1% concentration, the mean reduction in adherence was 52.9%. The monosaccharides studied may have a potential role in the management of Pseudomonas infections in dogs...
  4. doi request reprint Efficacy of a 0.0584% hydrocortisone aceponate spray in presumed feline allergic dermatitis: an open label pilot study
    Vanessa Schmidt
    School of Veterinary Science, The University of Liverpool, Leahurst, Cheshire CH64 7TE, UK
    Vet Dermatol 23:11-6, e3-4. 2012
    ..Six cats required every-other-day treatment and four required daily treatment. In conclusion, HCA spray appeared to be effective and safe in these cats, although it is not licensed for use in this species...
  5. doi request reprint Staphylococcal colonization of mucosal and lesional skin sites in atopic and healthy dogs
    Jennifer Fazakerley
    Department of Veterinary Clinical Science, The University of Liverpool, Faculty of Veterinary Science, Liverpool, UK
    Vet Dermatol 20:179-84. 2009
    ..The results show that S. intermedius carriage is more prevalent in atopic dogs compared to healthy dogs and that to identify staphylococcal carriers both the nasal mucosa and the perineum should be sampled...
  6. doi request reprint A two-dimensional morphological study of corneocytes from healthy dogs and cats and from dogs with atopic dermatitis
    Neil A McEwan
    Small Animal Teaching Hospital, The University of Liverpool, Leahurst Campus Neston, Wirral, UK
    Vet Dermatol 20:360-8. 2009
    ..8-9.9 microm and 117.6-245.6 microm(2). The exact nature of the elongated cells is not known but they may be cell fragments or folded corneocytes. They were more common in densely haired skin suggesting the hair follicle as their origin...
  7. doi request reprint Despite identifying some shared gene associations with human atopic dermatitis the use of multiple dog breeds from various locations limits detection of gene associations in canine atopic dermatitis
    Shona H Wood
    Department of Comparative Molecular Medicine, School of Veterinary Science, The University of Liverpool, Liverpool, UK
    Vet Immunol Immunopathol 138:193-7. 2010
    ..This study therefore suggests that further candidate gene studies in cAD should be breed and location specific to increase the likelihood of finding associations with the disease...
  8. doi request reprint Reference genes for canine skin when using quantitative real-time PCR
    Shona H Wood
    Department of Veterinary Pathology, Faculty of Veterinary Science, University of Liverpool, Liverpool, UK
    Vet Immunol Immunopathol 126:392-5. 2008
    ..RPL13A and CG14980 were found to be the most stably expressed genes in canine whole skin and would be more suitable as reference genes in future studies...
  9. doi request reprint Gene expression in canine atopic dermatitis and correlation with clinical severity scores
    Shona H Wood
    Department of Veterinary Pathology, Faculty of Veterinary Science, University of Liverpool, Liverpool, UK
    J Dermatol Sci 55:27-33. 2009
    ..Canine atopic dermatitis (cAD) is a common condition in dogs that may be a naturally occurring model for human atopic dermatitis (hAD). Despite this, comparative research is limited, particularly into the genetic background of cAD...
  10. doi request reprint Tris-EDTA significantly enhances antibiotic efficacy against multidrug-resistant Pseudomonas aeruginosa in vitro
    Laura M Buckley
    School of Veterinary Science, The University of Liverpool, Leahurst Campus, Neston, Cheshire, CH64 7TE, UK
    Vet Dermatol 24:519-e122. 2013
    ..Multidrug-resistant Pseudomonas aeruginosa commonly complicates chronic bacterial otitis in dogs...
  11. doi request reprint Comparable efficacy of a topical 0.0584% hydrocortisone aceponate spray and oral ciclosporin in treating canine atopic dermatitis
    Tim J Nuttall
    Department of Infection Biology, The University of Liverpool, Leahurst, Cheshire CH64 7TE, UK
    Vet Dermatol 23:4-10, e1-2. 2012
    ..008). Five HCA-treated dogs and three ciclosporin-treated dogs were prematurely withdrawn (P=0.7). In conclusion, HCA and ciclosporin proved equally effective in treating canine atopic dermatitis for up to 84 days...
  12. ncbi request reprint Staphylococcal and micrococcal adherence to canine and feline corneocytes: quantification using a simple adhesion assay
    Yi Fang Lu
    Division of Companion Animal Studies, Institute of Comparative Medicine, University of Glasgow Veterinary School, Bearsden, Glasgow G61 1QH, UK
    Vet Dermatol 18:29-35. 2007
    ..Both Staphylococcus hominis and a Micrococcus species adhered poorly to canine and feline corneocytes. This is the first report documenting bacterial adhesion to feline corneocytes...
  13. ncbi request reprint Immunoglobulin levels in Bull terriers suffering from lethal acrodermatitis
    N A McEwan
    Department of Veterinary Clinical Studies, Institute of Comparative Medicine, University of Glasgow Veterinary School, Bearsden, Glasgow G61 1QH, UK
    Vet Immunol Immunopathol 96:235-8. 2003
    ..This finding may in part explain the frequent occurrence of microbial infections recorded in dogs suffering from LAD...
  14. doi request reprint Gene (mRNA) expression in canine atopic dermatitis: microarray analysis
    Annemarie E Merryman-Simpson
    Waltham Centre for Pet Nutrition, Melton Mowbray, Leicestershire, UK
    Vet Dermatol 19:59-66. 2008
    ..Investigating gene polymorphisms in the targets identified in this study will help improve our understanding of the genetic basis of this disease...