Liam J Morrison

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. pmc Discovery of mating in the major African livestock pathogen Trypanosoma congolense
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow Biomedical Research Centre, Glasgow, United Kingdom
    PLoS ONE 4:e5564. 2009
  2. pmc Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom
    Am J Trop Med Hyg 76:1132-7. 2007
  3. doi request reprint Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, United Kingdom
    Infect Genet Evol 8:847-54. 2008
  4. pmc Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection
    Liam J Morrison
    Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, United Kingdom
    Infect Immun 78:1096-108. 2010
  5. pmc A major genetic locus in Trypanosoma brucei is a determinant of host pathology
    Liam J Morrison
    Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, Glasgow, United Kingdom
    PLoS Negl Trop Dis 3:e557. 2009
  6. pmc The population structure of the Cryptosporidium parvum population in Scotland: a complex picture
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, UK
    Infect Genet Evol 8:121-9. 2008
  7. pmc Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map
    Anneli Cooper
    Wellcome Centre for Molecular Parasitology, Glasgow Biomedical Research Centre, University Place, Glasgow G12 8TA, UK
    Genome Biol 9:R103. 2008
  8. pmc Trypanosomosis in The Gambia: prevalence in working horses and donkeys detected by whole genome amplification and PCR, and evidence for interactions between trypanosome species
    Gina L Pinchbeck
    Faculty of Veterinary Science, University of Liverpool, Leahurst, Neston, CH64 7TE, UK
    BMC Vet Res 4:7. 2008
  9. doi request reprint Trypanosoma vivax displays a clonal population structure
    Craig W Duffy
    Wellcome Centre for Molecular Parasitology, Glasgow Biomedical Research Centre, Faculty of Veterinary Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom
    Int J Parasitol 39:1475-83. 2009
  10. doi request reprint Trypanosome genetics: populations, phenotypes and diversity
    Andy Tait
    Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom
    Vet Parasitol 181:61-8. 2011

Collaborators

Detail Information

Publications17

  1. pmc Discovery of mating in the major African livestock pathogen Trypanosoma congolense
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow Biomedical Research Centre, Glasgow, United Kingdom
    PLoS ONE 4:e5564. 2009
    ....
  2. pmc Use of multiple displacement amplification to increase the detection and genotyping of trypanosoma species samples immobilized on FTA filters
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow, United Kingdom
    Am J Trop Med Hyg 76:1132-7. 2007
    ..The use of MDA allows maximal use of finite DNA samples and may prove a valuable tool in studies where multiple reactions are necessary, such as population genetic analyses...
  3. doi request reprint Trypanosoma brucei gambiense Type 1 populations from human patients are clonal and display geographical genetic differentiation
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, United Kingdom
    Infect Genet Evol 8:847-54. 2008
    ..The finding of distinct clades in different places suggests the possibility that samples from humans with clinical signs represent clonal expansions from an underlying population that requires identifying and characterising...
  4. pmc Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection
    Liam J Morrison
    Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, United Kingdom
    Infect Immun 78:1096-108. 2010
    ..Furthermore, it is necessary to incorporate parasite variation into both experimental systems and models of pathogenesis...
  5. pmc A major genetic locus in Trypanosoma brucei is a determinant of host pathology
    Liam J Morrison
    Wellcome Trust Centre for Molecular Parasitology, University of Glasgow, Biomedical Research Centre, Glasgow, United Kingdom
    PLoS Negl Trop Dis 3:e557. 2009
    ..The identification of parasite loci is a first step towards identifying the genes that are responsible for these important traits and shows the power of genetic analysis as a tool for dissecting complex quantitative phenotypic traits...
  6. pmc The population structure of the Cryptosporidium parvum population in Scotland: a complex picture
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, Glasgow Biomedical Research Centre, 120 University Place, Glasgow G12 8TA, UK
    Infect Genet Evol 8:121-9. 2008
    ..Thus, the population structure of C. parvum is complex, with sub-populations differing in structure and being influenced by host movements, including the introduction of novel multilocus genotypes from geographically distinct regions...
  7. pmc Genetic analysis of the human infective trypanosome Trypanosoma brucei gambiense: chromosomal segregation, crossing over, and the construction of a genetic map
    Anneli Cooper
    Wellcome Centre for Molecular Parasitology, Glasgow Biomedical Research Centre, University Place, Glasgow G12 8TA, UK
    Genome Biol 9:R103. 2008
    ..As an essential step toward identifying loci that determine important traits in the human-infective subspecies, we report the construction of a high-resolution genetic map of the STIB 386 strain of T. b. gambiense...
  8. pmc Trypanosomosis in The Gambia: prevalence in working horses and donkeys detected by whole genome amplification and PCR, and evidence for interactions between trypanosome species
    Gina L Pinchbeck
    Faculty of Veterinary Science, University of Liverpool, Leahurst, Neston, CH64 7TE, UK
    BMC Vet Res 4:7. 2008
    ....
  9. doi request reprint Trypanosoma vivax displays a clonal population structure
    Craig W Duffy
    Wellcome Centre for Molecular Parasitology, Glasgow Biomedical Research Centre, Faculty of Veterinary Medicine, University of Glasgow, Glasgow G12 8TA, United Kingdom
    Int J Parasitol 39:1475-83. 2009
    ..vivax...
  10. doi request reprint Trypanosome genetics: populations, phenotypes and diversity
    Andy Tait
    Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, United Kingdom
    Vet Parasitol 181:61-8. 2011
    ....
  11. pmc Population genetics of Trypanosoma brucei rhodesiense: clonality and diversity within and between foci
    Craig W Duffy
    Wellcome Trust Centre for Molecular Parasitology, Institute of Biodiversity, Animal Health and Comparative Medicine, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    PLoS Negl Trop Dis 7:e2526. 2013
    ....
  12. ncbi request reprint Probabilistic order in antigenic variation of Trypanosoma brucei
    Liam J Morrison
    Wellcome Centre for Molecular Parasitology, University of Glasgow, 56 Dumbarton Rd, Glasgow, G11 6NU, Scotland, UK
    Int J Parasitol 35:961-72. 2005
    ....
  13. doi request reprint Antigenic variation in the African trypanosome: molecular mechanisms and phenotypic complexity
    Liam J Morrison
    University of Glasgow, Wellcome Centre for Molecular Parasitology and Division of Infection and Immunity, Glasgow Biomedical Research Centre, 120 University Place, Glasgow, G12 8TA, UK
    Cell Microbiol 11:1724-34. 2009
    ....
  14. pmc The animal trypanosomiases and their chemotherapy: a review
    Federica Giordani
    Wellcome Trust Centre for Molecular Parasitology, Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow G12 8TA, UK
    Parasitology 143:1862-1889. 2016
    ....
  15. pmc A Pre-clinical Animal Model of Trypanosoma brucei Infection Demonstrating Cardiac Dysfunction
    Charlotte S McCarroll
    Institute of Cardiovascular and Medical Sciences, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    PLoS Negl Trop Dis 9:e0003811. 2015
    ....
  16. pmc Trypanosoma brucei cathepsin-L increases arrhythmogenic sarcoplasmic reticulum-mediated calcium release in rat cardiomyocytes
    Elspeth B Elliott
    College of Medical, Veterinary and Life Sciences, Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow Cardiovascular Research Centre, University Place, Glasgow G12 8TA, UK
    Cardiovasc Res 100:325-35. 2013
    ..The current study exposed isolated ventricular cardiomyocytes and adult rat hearts to T. brucei to test whether trypanosomes can alter cardiac function independent of a systemic inflammatory/immune response...
  17. pmc Pyrimidine biosynthesis is not an essential function for Trypanosoma brucei bloodstream forms
    Juma A M Ali
    Institute of Infection, Immunity and Inflammation, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, United Kingdom
    PLoS ONE 8:e58034. 2013
    ..African trypanosomes are capable of both pyrimidine biosynthesis and salvage of preformed pyrimidines from the host, but it is unknown whether either process is essential to the parasite...