- Navarro P, Moffat M, Mullin N, Chambers I. The X-inactivation trans-activator Rnf12 is negatively regulated by pluripotency factors in embryonic stem cells. Hum Genet. 2011;130:255-64 pubmed publisher..We conclude that in mouse ES cells the pluripotency-associated machinery exerts an exhaustive control of X-inactivation by taking over the regulation of all three major regulators of X-inactivation: Xist, Tsix, and Rnf12. ..
- Navarro P, Oldfield A, Legoupi J, Festuccia N, Dubois A, Attia M, et al. Molecular coupling of Tsix regulation and pluripotency. Nature. 2010;468:457-60 pubmed publisher..The holistic pattern of Xist/Tsix regulation by pluripotent factors that we have identified suggests a general direct governance of complex epigenetic processes by the machinery dedicated to pluripotency. ..