M Notara

Summary

Affiliation: University College London
Country: UK

Publications

  1. doi Cytocompatibility and hemocompatibility of a novel chitosan-alginate gel system
    M Notara
    Bioengineering Group, School of Mechanical, Materials and Manufacturing Engineering, University of Nottingham, Nottingham, NG7 2RD, United Kingdom
    J Biomed Mater Res A 89:854-64. 2009
  2. pmc The impact of age on the physical and cellular properties of the human limbal stem cell niche
    M Notara
    Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Age (Dordr) 35:289-300. 2013
  3. doi Benign prostate hyperplasia and stem cells: a new therapeutic opportunity
    Maria Notara
    Prostate Cancer Research Centre, Research Department of Urology, Charles Bell House, University College London, 67 73 Riding House Street, W1W 7EJ, London, UK
    Cell Biol Toxicol 28:435-42. 2012
  4. doi Characterization of the phenotype and functionality of corneal epithelial cells derived from mouse embryonic stem cells
    Maria Notara
    Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Regen Med 7:167-78. 2012
  5. doi The porcine limbal epithelial stem cell niche as a new model for the study of transplanted tissue-engineered human limbal epithelial cells
    Maria Notara
    Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom
    Tissue Eng Part A 17:741-50. 2011
  6. doi IL6 and the human limbal stem cell niche: a mediator of epithelial-stromal interaction
    Maria Notara
    Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Stem Cell Res 5:188-200. 2010
  7. doi In sickness and in health: Corneal epithelial stem cell biology, pathology and therapy
    M Notara
    Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, Cells for Sight Transplantation and Research Programme, 11 43 Bath Street, London EC1V 9EL, UK
    Exp Eye Res 90:188-95. 2010
  8. doi Characterisation and functional features of a spontaneously immortalised human corneal epithelial cell line with progenitor-like characteristics
    Maria Notara
    Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, Institute of Ophthalmology, 11 43 Bath Street, London, EC1V 9EL, UK
    Brain Res Bull 81:279-86. 2010
  9. ncbi A xenobiotic-free culture system for human limbal epithelial stem cells
    Maria Notara
    UCL Institute of Ophthalmology, Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, 11 43 Bath Street, London, EC1V 9EL, UK
    Regen Med 2:919-27. 2007
  10. ncbi Plasma polymer coated surfaces for serum-free culture of limbal epithelium for ocular surface disease
    Maria Notara
    Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, UCL Institute of Ophthalmology, 11 43 Bath Street, London, EC1V 9EL
    J Mater Sci Mater Med 18:329-38. 2007

Collaborators

Detail Information

Publications14

  1. doi Cytocompatibility and hemocompatibility of a novel chitosan-alginate gel system
    M Notara
    Bioengineering Group, School of Mechanical, Materials and Manufacturing Engineering, University of Nottingham, Nottingham, NG7 2RD, United Kingdom
    J Biomed Mater Res A 89:854-64. 2009
    ..Further platelet activation by the surfaces was also minimal. These results indicate that these novel gels merit further investigation for blood contact applications...
  2. pmc The impact of age on the physical and cellular properties of the human limbal stem cell niche
    M Notara
    Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Age (Dordr) 35:289-300. 2013
    ..Overall, the data also suggest that LESCs harvested from younger donors may be more suitable for cultured LESC therapy production...
  3. doi Benign prostate hyperplasia and stem cells: a new therapeutic opportunity
    Maria Notara
    Prostate Cancer Research Centre, Research Department of Urology, Charles Bell House, University College London, 67 73 Riding House Street, W1W 7EJ, London, UK
    Cell Biol Toxicol 28:435-42. 2012
    ..This review focuses on this putative role of stromal stem or stem-like cells in the development of BPH and assesses the potential of targeting the stem cells for the treatment of BPH...
  4. doi Characterization of the phenotype and functionality of corneal epithelial cells derived from mouse embryonic stem cells
    Maria Notara
    Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Regen Med 7:167-78. 2012
    ..To investigate the optimum conditions for the differentiation of a mouse embryonic stem cell line towards corneal epithelial cell fate...
  5. doi The porcine limbal epithelial stem cell niche as a new model for the study of transplanted tissue-engineered human limbal epithelial cells
    Maria Notara
    Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom
    Tissue Eng Part A 17:741-50. 2011
    ..These data have significant clinical value as this model can provide information on LESC fate post-transplantation and their ability to respond to injury, which is not possible to study in patients...
  6. doi IL6 and the human limbal stem cell niche: a mediator of epithelial-stromal interaction
    Maria Notara
    Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Stem Cell Res 5:188-200. 2010
    ..STAT3 and IL6 inhibition in 3.1SF cultures significantly reduced HLE colony-forming efficiency, suggesting a previously undetected STAT3-mediated involvement of IL6 in the maintenance of HLE cells in a progenitor-like state...
  7. doi In sickness and in health: Corneal epithelial stem cell biology, pathology and therapy
    M Notara
    Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, Cells for Sight Transplantation and Research Programme, 11 43 Bath Street, London EC1V 9EL, UK
    Exp Eye Res 90:188-95. 2010
    ..The clinical precedence for use of stem cell therapy and the accessibility of the transparent stem cell niche make the cornea a unique model for the study of adult stem cells in physiological conditions as well as in disease...
  8. doi Characterisation and functional features of a spontaneously immortalised human corneal epithelial cell line with progenitor-like characteristics
    Maria Notara
    Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, Institute of Ophthalmology, 11 43 Bath Street, London, EC1V 9EL, UK
    Brain Res Bull 81:279-86. 2010
    ....
  9. ncbi A xenobiotic-free culture system for human limbal epithelial stem cells
    Maria Notara
    UCL Institute of Ophthalmology, Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, 11 43 Bath Street, London, EC1V 9EL, UK
    Regen Med 2:919-27. 2007
    ....
  10. ncbi Plasma polymer coated surfaces for serum-free culture of limbal epithelium for ocular surface disease
    Maria Notara
    Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, UCL Institute of Ophthalmology, 11 43 Bath Street, London, EC1V 9EL
    J Mater Sci Mater Med 18:329-38. 2007
    ..These results suggest that these surfaces can be used successfully for the serum-free expansion of human limbal epithelial cells...
  11. doi Conjunctival epithelial cells maintain stem cell properties after long-term culture and cryopreservation
    S Schrader
    Cells for Sight Transplantation and Research Programme, Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, EC1V 9EL, London, UK
    Regen Med 4:677-87. 2009
    ..The aim of this study was to evaluate whether cryopreservation and long-term in vitro culture has an effect on the proliferative capacity and the progenitor-like cell characteristics of conjunctival epithelial cells...
  12. ncbi Limbal epithelial stem cell therapy
    Julie T Daniels
    UCL Institute of Ophthalmology, Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, Division of Pathology, London, EC1V 9EL, UK
    Expert Opin Biol Ther 7:1-3. 2007
    ....
  13. doi Tissue engineering for conjunctival reconstruction: established methods and future outlooks
    Stefan Schrader
    Cells for Sight Transplantation and Research Programme, Department of Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, UK
    Curr Eye Res 34:913-24. 2009
    ..This article reviews the present approaches for reconstruction of the conjunctival surface, considering the established strategies and new potential methodologies...
  14. ncbi Biological principals and clinical potentials of limbal epithelial stem cells
    Maria Notara
    Cells for Sight Transplantation and Research Programme, Ocular Repair and Regeneration Biology Unit, Institute of Ophthalmology, 11 43 Bath Street, London, EC1V 9EL, UK
    Cell Tissue Res 331:135-43. 2008
    ..The clinical precedence for the use of stem cell therapy and the ready accessibility of a transparent stem cell niche make the cornea a unique model for the study of adult stem cells in health and disease...