M J Wall

Summary

Affiliation: University of Warwick
Country: UK

Publications

  1. ncbi The speeding of EPSC kinetics during maturation of a central synapse
    Mark J Wall
    Department of Pharmacology, University of Bristol, University Walk, Bristol, BS8 1TD, UK
    Eur J Neurosci 15:785-97. 2002
  2. ncbi Cis-4-amino-crotonic acid activates alpha 6 subunit-containing GABA(A) but not GABA(C) receptors in granule cells of adult rat cerebellar slices
    M J Wall
    Neurobiology Group, Department of Biological Sciences, University of Warwick, Warwick, CV4 7AL, UK
    Neurosci Lett 316:37-40. 2001
  3. ncbi A role for zinc in cerebellar synaptic transmission?
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry, UK
    Cerebellum 4:224-9. 2005
  4. ncbi Alterations in GABAA receptor occupancy occur during the postnatal development of rat Purkinje cell but not granule cell synapses
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neuropharmacology 49:596-609. 2005
  5. ncbi Short-term synaptic plasticity during development of rat mossy fibre to granule cell synapses
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Eur J Neurosci 21:2149-58. 2005
  6. ncbi Actions of zinc at mature Golgi cell to granule cell synapses in cerebellum of rats and mice
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neurosci Lett 367:101-4. 2004
  7. ncbi Endogenous nitric oxide modulates GABAergic transmission to granule cells in adult rat cerebellum
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Eur J Neurosci 18:869-78. 2003
  8. ncbi Competitive GABA(A) receptor antagonists increase the proportion of functional high-affinity alpha6 subunit-containing receptors in granule cells of adult rat cerebellum
    Mark J Wall
    Neurobiology Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neuropharmacology 44:56-69. 2003
  9. ncbi Furosemide reveals heterogeneous GABA(A) receptor expression at adult rat Golgi cell to granule cell synapses
    Mark J Wall
    Neurobiology Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neuropharmacology 43:737-49. 2002
  10. pmc Adenosine signalling at immature parallel fibre-Purkinje cell synapses in rat cerebellum
    Alison Atterbury
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    J Physiol 587:4497-508. 2009

Collaborators

  • Nicholas Dale
  • James Howe
  • Alison Atterbury
  • Sanath K Meegalla
  • Daniel A Press
  • Carl S Crysler
  • Mark R Player
  • Carl L Manthey
  • Shelley K Ballentine
  • Margery A Chaikin
  • Jinsheng Chen
  • Carl R Illig
  • Bruce E Tomczuk
  • Carsten Schubert
  • Yanmin Chen
  • Christopher J Molloy
  • Kenneth J Wilson
  • Renee L DesJarlais

Detail Information

Publications15

  1. ncbi The speeding of EPSC kinetics during maturation of a central synapse
    Mark J Wall
    Department of Pharmacology, University of Bristol, University Walk, Bristol, BS8 1TD, UK
    Eur J Neurosci 15:785-97. 2002
    ..Desensitization becomes increasingly important during development and plays a major role in shaping EPSC decay at mature synapses...
  2. ncbi Cis-4-amino-crotonic acid activates alpha 6 subunit-containing GABA(A) but not GABA(C) receptors in granule cells of adult rat cerebellar slices
    M J Wall
    Neurobiology Group, Department of Biological Sciences, University of Warwick, Warwick, CV4 7AL, UK
    Neurosci Lett 316:37-40. 2001
    ..GABAergic synaptic currents were blocked by low concentrations of bicuculline, but not by TPMPA. Thus, cerebellar granule cells express functional GABA(A) but not GABA(C) receptors...
  3. ncbi A role for zinc in cerebellar synaptic transmission?
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry, UK
    Cerebellum 4:224-9. 2005
    ..Thus it is possible that the different types of zinc transporter found in the cerebellum play a neuroprotective rather than a signalling role...
  4. ncbi Alterations in GABAA receptor occupancy occur during the postnatal development of rat Purkinje cell but not granule cell synapses
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neuropharmacology 49:596-609. 2005
    ..Thus during development, the level of receptor occupation remains constant at Golgi cell to granule cell synapses but falls at Purkinje cell synapses...
  5. ncbi Short-term synaptic plasticity during development of rat mossy fibre to granule cell synapses
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Eur J Neurosci 21:2149-58. 2005
    ..At mature synapses, postsynaptic receptor desensitization appears to be the major cause of depression...
  6. ncbi Actions of zinc at mature Golgi cell to granule cell synapses in cerebellum of rats and mice
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neurosci Lett 367:101-4. 2004
    ..Thus, there is no physiological evidence that zinc is released from Golgi cells to modulate GABAergic transmission...
  7. ncbi Endogenous nitric oxide modulates GABAergic transmission to granule cells in adult rat cerebellum
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Eur J Neurosci 18:869-78. 2003
    ..NO is a potentially novel mechanism for tuning GABAergic signalling to granule cells and therefore modulating the throughput of an important cerebellar circuit...
  8. ncbi Competitive GABA(A) receptor antagonists increase the proportion of functional high-affinity alpha6 subunit-containing receptors in granule cells of adult rat cerebellum
    Mark J Wall
    Neurobiology Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neuropharmacology 44:56-69. 2003
    ..This hypothesis appears feasible as prolonged applications of low concentrations of GABA to recombinant alpha6beta2gamma2s receptors resulted in their desensitisation...
  9. ncbi Furosemide reveals heterogeneous GABA(A) receptor expression at adult rat Golgi cell to granule cell synapses
    Mark J Wall
    Neurobiology Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Neuropharmacology 43:737-49. 2002
    ..Thus the GABA(A) receptors present at adult Golgi cell-granule cell synapses, at a developmental stage where receptor expression is complete, are highly heterogeneous...
  10. pmc Adenosine signalling at immature parallel fibre-Purkinje cell synapses in rat cerebellum
    Alison Atterbury
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    J Physiol 587:4497-508. 2009
    ..In conclusion, at this stage of development, although adenosine receptors and the mechanisms of adenosine clearance are present there is very little adenosine release...
  11. pmc Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    J Physiol 581:553-65. 2007
    ..This activity-dependent adenosine release exerts feedback inhibition of parallel fibre-Purkinje cell transmission. Spike-mediated adenosine release from parallel fibres will thus powerfully regulate cerebellar circuit output...
  12. doi The novel NTPDase inhibitor sodium polyoxotungstate (POM-1) inhibits ATP breakdown but also blocks central synaptic transmission, an action independent of NTPDase inhibition
    Mark J Wall
    Department of Biological Sciences, University of Warwick, Gibbet Hill, Warwickshire, Coventry CV4 7AL, United Kingdom
    Neuropharmacology 55:1251-8. 2008
    ..Thus although POM-1 is more effective than ARL 67156 at blocking ATP breakdown its usefulness is limited by off-target actions on synaptic transmission...
  13. pmc Control of basal extracellular adenosine concentration in rat cerebellum
    Mark J Wall
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    J Physiol 582:137-51. 2007
    ..The increased spatial and temporal resolution of the purine biosensor measurements has revealed the complexity of the control of adenosine and purine tone in the cerebellum...
  14. ncbi Expression of cocaine- and amphetamine-regulated transcript (CART) peptides at climbing fibre-Purkinje cell synapses in the rat vestibular cerebellum
    Daniel A Press
    Neuroscience Group, Department of Biological Sciences, University of Warwick, Gibbet Hill, Warwickshire CV4 7AL, UK
    Neuropeptides 42:39-46. 2008
    ....
  15. doi Structure-based optimization of a potent class of arylamide FMS inhibitors
    Sanath K Meegalla
    Johnson and Johnson Pharmaceutical Research and Development, Welsh and McKean Roads, Spring House, PA 19477, USA
    Bioorg Med Chem Lett 18:3632-7. 2008
    ..Structure-based modeling provided the framework to efficiently effect this transformation and restore potencies to previous levels. This optimization removed a risk factor for potential idiosyncratic drug reactions...