T A Thanaraj

Summary

Affiliation: Wellcome Trust Genome Campus
Country: UK

Publications

  1. pmc Ribosome-mediated translational pause and protein domain organization
    T A Thanaraj
    European Molecular Biology Laboratory, Heidelberg, Germany
    Protein Sci 5:1594-612. 1996
  2. pmc ASD: a bioinformatics resource on alternative splicing
    Stefan Stamm
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
    Nucleic Acids Res 34:D46-55. 2006
  3. pmc Protein secondary structural types are differentially coded on messenger RNA
    T A Thanaraj
    European Molecular Biology Laboratory, Heidelberg, Germany
    Protein Sci 5:1973-83. 1996
  4. pmc A clean data set of EST-confirmed splice sites from Homo sapiens and standards for clean-up procedures
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 27:2627-37. 1999
  5. pmc Positional characterisation of false positives from computational prediction of human splice sites
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 28:744-54. 2000
  6. pmc Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK and University of Queensland, St Lucia, 4072, Australia
    Nucleic Acids Res 29:2581-93. 2001
  7. ncbi request reprint Prediction of exact boundaries of exons
    T A Thanaraj
    European Bioinformatics Institute, Hinxton, UK
    Brief Bioinform 1:343-56. 2000
  8. pmc ASD: the Alternative Splicing Database
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 32:D64-9. 2004
  9. pmc Conservation of human alternative splice events in mouse
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 31:2544-52. 2003
  10. ncbi request reprint Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human
    Francis Clark
    Advanced Computation and Modeling Center, University of Queensland, St Lucia, 4072, Australia
    Hum Mol Genet 11:451-64. 2002

Detail Information

Publications12

  1. pmc Ribosome-mediated translational pause and protein domain organization
    T A Thanaraj
    European Molecular Biology Laboratory, Heidelberg, Germany
    Protein Sci 5:1594-612. 1996
    ..Examination of available mutagenic data indicated that the effects of some of the reported mutations were consistent with our hypothesis...
  2. pmc ASD: a bioinformatics resource on alternative splicing
    Stefan Stamm
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
    Nucleic Acids Res 34:D46-55. 2006
    ..ASD data has been integrated with Ensembl genome annotation project as a Distributed Annotation System (DAS) resource and can be viewed on Ensembl genome browser. The ASD resource is presented at (http://www.ebi.ac.uk/asd)...
  3. pmc Protein secondary structural types are differentially coded on messenger RNA
    T A Thanaraj
    European Molecular Biology Laboratory, Heidelberg, Germany
    Protein Sci 5:1973-83. 1996
    ..The observed absence of such strong positive selection for codons in non-highly expressed genes is compatible with existing theories that mutation pressure may well dominate codon selection in non-highly expressed genes...
  4. pmc A clean data set of EST-confirmed splice sites from Homo sapiens and standards for clean-up procedures
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 27:2627-37. 1999
    ..A set of nucleotide regions that can be used to generate a control set of false splice sites that have a high confidence of being non-functional are also reported...
  5. pmc Positional characterisation of false positives from computational prediction of human splice sites
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 28:744-54. 2000
    ..It is therefore suggested that specialised statistics that can discriminate real splice sites from proximal false positives be incorporated in gene prediction programs...
  6. pmc Human GC-AG alternative intron isoforms with weak donor sites show enhanced consensus at acceptor exon positions
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK and University of Queensland, St Lucia, 4072, Australia
    Nucleic Acids Res 29:2581-93. 2001
    ..The other important findings include (i) one in every twenty alternative introns is a GC-AG intron, and (ii) three of every five observed GC-AG introns are alternative isoforms...
  7. ncbi request reprint Prediction of exact boundaries of exons
    T A Thanaraj
    European Bioinformatics Institute, Hinxton, UK
    Brief Bioinform 1:343-56. 2000
    ....
  8. pmc ASD: the Alternative Splicing Database
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK
    Nucleic Acids Res 32:D64-9. 2004
    ..The data are presented on our ASD web pages (http://www.ebi.ac.uk/asd)...
  9. pmc Conservation of human alternative splice events in mouse
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1SD, UK
    Nucleic Acids Res 31:2544-52. 2003
    ..This, combined with the preservation of alternative frame stop codons in conserved frame breaking events, indicates a high level of commonality in patterns of gene expression between these two species...
  10. ncbi request reprint Categorization and characterization of transcript-confirmed constitutively and alternatively spliced introns and exons from human
    Francis Clark
    Advanced Computation and Modeling Center, University of Queensland, St Lucia, 4072, Australia
    Hum Mol Genet 11:451-64. 2002
    ..The 'AltExtron' data sets are available at http://www.bit.uq.edu.au/altExtron/ and http://www.ebi.ac.uk/~thanaraj/altExtron/...
  11. ncbi request reprint Prediction and statistical analysis of alternatively spliced exons
    T A Thanaraj
    European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1SD, UK
    Prog Mol Subcell Biol 31:1-31. 2003
  12. ncbi request reprint Function of alternative splicing
    Stefan Stamm
    Institute for Biochemistry, University of Erlangen, Fahrstrasse 17, 91054 Erlangen, Germany
    Gene 344:1-20. 2005
    ..Therefore, evidence is now accumulating that alternative splicing coordinates physiologically meaningful changes in protein isoform expression and is a key mechanism to generate the complex proteome of multicellular organisms...