Darrell R Kapczynski

Summary

Affiliation: Agricultural Research Service
Country: USA

Publications

  1. doi request reprint Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus
    Darrell R Kapczynski
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, United States Electronic address
    Vaccine 33:1197-205. 2015
  2. doi request reprint Characterization of cytokine expression induced by avian influenza virus infection with real-time RT-PCR
    Darrell R Kapczynski
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, 934 College Station Road, Athens, GA, 30605, USA
    Methods Mol Biol 1161:217-33. 2014
  3. doi request reprint Detection of cell-mediated immune response to avian influenza viruses
    Darrell R Kapczynski
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, 934 College Station Rd, Athens, GA, 30605, USA
    Methods Mol Biol 1161:199-215. 2014
  4. pmc Transcription factor regulation and cytokine expression following in vitro infection of primary chicken cell culture with low pathogenic avian influenza virus
    Haijun Jiang
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, Greece
    Virol J 10:342. 2013
  5. pmc Characterization of the 2012 highly pathogenic avian influenza H7N3 virus isolated from poultry in an outbreak in Mexico: pathobiology and vaccine protection
    Darrell R Kapczynski
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, Athens, Georgia, USA
    J Virol 87:9086-96. 2013
  6. doi request reprint Immune responses of poultry to Newcastle disease virus
    Darrell R Kapczynski
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, Athens, GA 30605, United States
    Dev Comp Immunol 41:447-53. 2013
  7. ncbi request reprint Protection from clinical disease against three highly virulent strains of Newcastle disease virus after in ovo application of an antibody-antigen complex vaccine in maternal antibody-positive chickens
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 56:555-60. 2012
  8. ncbi request reprint Pandemic H1N1 influenza virus in Chilean commercial turkeys with genetic and serologic comparisons to U.S. H1N1 avian influenza vaccine isolates
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 55:633-41. 2011
  9. pmc Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in lung cell cultures from different avian species
    Haijun Jiang
    Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, People s Republic of China
    Virol J 8:447. 2011
  10. ncbi request reprint Vaccine-induced protection from egg production losses in commercial turkey breeder hens following experimental challenge with a triple-reassortant H3N2 avian influenza virus
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, Georgia 30605, USA
    Avian Dis 53:7-15. 2009

Collaborators

Detail Information

Publications47

  1. doi request reprint Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus
    Darrell R Kapczynski
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, United States Electronic address
    Vaccine 33:1197-205. 2015
    ....
  2. doi request reprint Characterization of cytokine expression induced by avian influenza virus infection with real-time RT-PCR
    Darrell R Kapczynski
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, 934 College Station Road, Athens, GA, 30605, USA
    Methods Mol Biol 1161:217-33. 2014
    ....
  3. doi request reprint Detection of cell-mediated immune response to avian influenza viruses
    Darrell R Kapczynski
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, 934 College Station Rd, Athens, GA, 30605, USA
    Methods Mol Biol 1161:199-215. 2014
    ..The increasing availability of monoclonal antibodies recognizing various avian cell-associated antigens has made this technique more specific and informative. ..
  4. pmc Transcription factor regulation and cytokine expression following in vitro infection of primary chicken cell culture with low pathogenic avian influenza virus
    Haijun Jiang
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, Greece
    Virol J 10:342. 2013
    ..However, there is limited information on the avian immune response to infection with low pathogenic avian influenza virus (LPAIV)...
  5. pmc Characterization of the 2012 highly pathogenic avian influenza H7N3 virus isolated from poultry in an outbreak in Mexico: pathobiology and vaccine protection
    Darrell R Kapczynski
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, Athens, Georgia, USA
    J Virol 87:9086-96. 2013
    ..This study demonstrates the pathological consequences of the infection of chickens with the 2012 Mexican lineage H7N3 HPAI virus and provides support for effective programs of vaccination against this virus in poultry. ..
  6. doi request reprint Immune responses of poultry to Newcastle disease virus
    Darrell R Kapczynski
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, Athens, GA 30605, United States
    Dev Comp Immunol 41:447-53. 2013
    ....
  7. ncbi request reprint Protection from clinical disease against three highly virulent strains of Newcastle disease virus after in ovo application of an antibody-antigen complex vaccine in maternal antibody-positive chickens
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 56:555-60. 2012
    ..Together, these results demonstrate the efficacy of AAC vaccines delivered in ovo to protect commercial poultry...
  8. ncbi request reprint Pandemic H1N1 influenza virus in Chilean commercial turkeys with genetic and serologic comparisons to U.S. H1N1 avian influenza vaccine isolates
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 55:633-41. 2011
    ....
  9. pmc Chicken interferon alpha pretreatment reduces virus replication of pandemic H1N1 and H5N9 avian influenza viruses in lung cell cultures from different avian species
    Haijun Jiang
    Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, People s Republic of China
    Virol J 8:447. 2011
    ..However, the mechanisms by which interferon inhibit virus replication in avian species remains unknown as does the biological activity of chicken interferon in other avian species...
  10. ncbi request reprint Vaccine-induced protection from egg production losses in commercial turkey breeder hens following experimental challenge with a triple-reassortant H3N2 avian influenza virus
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, Georgia 30605, USA
    Avian Dis 53:7-15. 2009
    ..This study provides the first detailed description of the clinical protection afforded to laying turkey hens by vaccination against challenge with a circulating field isolate of a H3N2 triple-reassortant AIV...
  11. pmc Cross reactive cellular immune responses in chickens previously exposed to low pathogenic avian influenza
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USA, Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    BMC Proc 5:S13. 2011
    ..In fact, little is known about cellular immunity following a primary AI infection in poultry, especially regarding cytotoxic T lymphocytes (CTL's)...
  12. doi request reprint Influenza vaccines for avian species
    Darrell R Kapczynski
    Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, USDA Agricultural Research Service South Atlantic Area, 934 College Station Road, Athens, GA 30605, USA
    Curr Top Microbiol Immunol 333:133-52. 2009
    ..In the current H5N1 HPAI epizootic, vaccines have been used in a variety of avian species as a part of an overall control program to aid in disease management and control...
  13. ncbi request reprint Genomic sequences of low-virulence avian paramyxovirus-1 (Newcastle disease virus) isolates obtained from live-bird markets in North America not related to commonly utilized commercial vaccine strains
    Bruce S Seal
    Southeast Poultry Research Laboratory, U S Department of Agriculture, Agricultural Research Service, 934 College Station Road, Athens, GA 360605, USA
    Vet Microbiol 106:7-16. 2005
    ..These APMV-1 genotypes have not been previously reported in North America and further substantiate the heterogeneous genetic nature of these commercially important pathogens found worldwide...
  14. ncbi request reprint Development of a virosome vaccine against avian metapneumovirus subtype C for protection in turkeys
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 48:332-43. 2004
    ..Increased virus-neutralizing antibody levels against aMPV were observed in birds vaccinated with virosomes. These results demonstrate that immunization of turkeys with aMPV virosomes can be an effective strategy for control of disease...
  15. ncbi request reprint Mucosal vaccination with formalin-inactivated avian metapneumovirus subtype C does not protect turkeys following intranasal challenge
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 52:28-33. 2008
    ..On the basis of these results it is concluded that intranasal vaccination with inactivated aMPV does not induce protective immunity, reduce virus shedding, or result in decreased histopathologic lesions...
  16. doi request reprint Effects of Newcastle disease virus vaccine antibodies on the shedding and transmission of challenge viruses
    Patti J Miller
    Exotic and Emerging Avian Disease Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA, United States Electronic address
    Dev Comp Immunol 41:505-13. 2013
    ....
  17. ncbi request reprint Protection of chickens against overt clinical disease and determination of viral shedding following vaccination with commercially available Newcastle disease virus vaccines upon challenge with highly virulent virus from the California 2002 exotic Newcastl
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, USA
    Vaccine 23:3424-33. 2005
    ..These results underscore the need to develop new NDV vaccines and vaccine strategies for use during outbreak situations to protect birds from both disease and infection to reduce virus shedding...
  18. doi request reprint Virulent Newcastle disease virus elicits a strong innate immune response in chickens
    Cary A Rue
    Southeast Poultry Research Laboratory, Agricultural Research Service, United States Department of Agriculture, Athens, GA 30605, USA
    J Gen Virol 92:931-9. 2011
    ..Taken together, these results suggest that the host response itself may contribute to the pathogenesis of this highly virulent strain in chickens...
  19. doi request reprint Effect of age on the pathogenesis and innate immune responses in Pekin ducks infected with different H5N1 highly pathogenic avian influenza viruses
    Mary J Pantin-Jackwood
    Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Virus Res 167:196-206. 2012
    ....
  20. ncbi request reprint Susceptibility and protection of naive and vaccinated racing pigeons (Columbia livia) against exotic Newcastle disease virus from the California 2002-2003 outbreak
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 50:336-41. 2006
    ..Overt clinical signs of disease were not observed in any PPMV-1-vaccinated birds after challenge...
  21. ncbi request reprint Immunization of turkeys with a DNA vaccine expressing either the F or N gene of avian metapneumovirus
    Darrell R Kapczynski
    Laboratory, Agricultural Research Service, Southeast Poultry Research United States Department of Agriculture, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 47:1376-83. 2003
    ..These results indicate that DNA vaccination with the F, but not N, gene of aMPV can induce significant protection against aMPV infection...
  22. pmc Pathogenicity and Transmission of H5 and H7 Highly Pathogenic Avian Influenza Viruses in Mallards
    Mary J Pantin-Jackwood
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, U S National Poultry Research Center, Agricultural Research Service, U S Department of Agriculture, Athens, Georgia, USA
    J Virol 90:9967-9982. 2016
    ..These three viruses were also shed in higher titers by the ducks, which could facilitate virus transmission and spread. This study highlights the possible role of wild waterfowl in the spread of HPAI viruses...
  23. pmc Experimental co-infections of domestic ducks with a virulent Newcastle disease virus and low or highly pathogenic avian influenza viruses
    Mary J Pantin-Jackwood
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Athens, GA 30605, USA Electronic address
    Vet Microbiol 177:7-17. 2015
    ..These findings indicate that infection with one virus can interfere with replication of another, modifying the pathogenesis and transmission of the viruses...
  24. pmc Previous infection with virulent strains of Newcastle disease virus reduces highly pathogenic avian influenza virus replication, disease, and mortality in chickens
    Mar Costa-Hurtado
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, United States National Poultry Research Center, Agricultural Research Service, U S Department of Agriculture, Athens, GA, USA
    Vet Res 46:97. 2015
    ..The information obtained from these studies helps to understand the possible interactions and outcomes of infection (disease and virus shedding) when HPAIV and NDV co-infect chickens in the field. ..
  25. ncbi request reprint Comparative susceptibility of chickens and turkeys to avian influenza A H7N2 virus infection and protective efficacy of a commercial avian influenza H7N2 virus vaccine
    Terrence M Tumpey
    Southeast Poultry Research Laboratory, United States Department of Agriculture, Agricultural Research Service, Athens, GA 30605, USA
    Avian Dis 48:167-76. 2004
    ..These results demonstrate the potential benefit of using an antigenically related 1997 H7N2 virus as a vaccine candidate for protection in poultry against a H7N2 virus isolate from 2002...
  26. ncbi request reprint Protection of chickens from infectious bronchitis by in ovo and intramuscular vaccination with a DNA vaccine expressing the S1 glycoprotein
    Darrell R Kapczynski
    University of Georgia, Poultry Diagnostic and Research Center, College of Veterinary Medicine, 953 College Station Road, Athens, GA 30602, USA
    Avian Dis 47:272-85. 2003
    ..These data indicate that DNA vaccination with the S1 gene either in ovo or intramuscularly can provide birds with some protection against clinical disease after homologous IBV challenge...
  27. pmc Development of a real-time reverse-transcription PCR for detection of newcastle disease virus RNA in clinical samples
    Mark G Wise
    Southeast Poultry Research Laboratory, Agricultural Research Service, US Department of Agriculture, Athens, Georgia 30605, USA
    J Clin Microbiol 42:329-38. 2004
    ..Overall, a positive correlation was obtained between the RRT-PCR results and virus isolation for NDV from clinical samples...
  28. ncbi request reprint Identification and characterization of two distinct bursal B-cell subpopulations following infectious bursal disease virus infection of White Leghorn chickens
    Daniel I Petkov
    Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Avian Dis 53:347-55. 2009
    ..Overall, these are the first studies to identify two distinct IgM B-cell subpopulations in the chicken bursa, and the first to describe the decrease in the IgM B-cell population relative to IgA and IgG B-cells following IBDV infection...
  29. doi request reprint Efficacy of a Recombinant Turkey Herpesvirus H5 Vaccine Against Challenge With H5N1 Clades 1.1.2 and 2.3.2.1 Highly Pathogenic Avian Influenza Viruses in Domestic Ducks (Anas platyrhynchos domesticus)
    Mary J Pantin-Jackwood
    A Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, United States National Poultry Research Center, Agricultural Research Service, United States Department of Agriculture, 934 College Station Road, Athens, GA 30605
    Avian Dis 60:22-32. 2016
    ..2 vaccine given alone in Pekin ducks against H5N1 HPAI viruses and only a minor additive effect on virus shedding reduction when used with an inactivated vaccine in a prime-boost regime. ..
  30. ncbi request reprint Phylogenetic analysis of the sigma 2 protein gene of turkey reoviruses
    Holly S Sellers
    Department of Avian Medicine, Poultry Diagnostic and Research Center, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Avian Dis 48:651-7. 2004
    ..In addition, as a result of the limited sequence identity with their avian counterparts, turkey reoviruses could potentially be considered a separate virus species within subgroup 2 of the Orthoreovirus genus...
  31. ncbi request reprint Full-length sequence analysis of four IBDV strains with different pathogenicities
    Daniel Petkov
    Department of Infectious Diseases, College of Veterinary Medicine, University of Georgia, Athens, GA 30602, USA
    Virus Genes 34:315-26. 2007
    ....
  32. pmc Vaccination with virus-like particles containing H5 antigens from three H5N1 clades protects chickens from H5N1 and H5N8 influenza viruses
    Darrell R Kapczynski
    USDA SEPRL, Athens, GA, USA
    Vaccine 34:1575-81. 2016
    ..S. H5N8 HPAI isolate. We conclude that these novel triple-clade VLPs represent a feasible strategy for simultaneously evoking protective antibodies against multiple variants of H5 influenza virus. ..
  33. pmc Changes in adaptation of H5N2 highly pathogenic avian influenza H5 clade 2.3.4.4 viruses in chickens and mallards
    Eric DeJesus
    Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U S National Poultry Research Center, Agricultural Research Service, U S Department of Agriculture, Athens, GA, USA Electronic address
    Virology 499:52-64. 2016
    ..Increased virus adaptation to chickens was observed with the poultry H5N2 viruses; however these viruses retained high adaptation to mallards but pathogenicity was differently affected...
  34. pmc Virus interference between H7N2 low pathogenic avian influenza virus and lentogenic Newcastle disease virus in experimental co-infections in chickens and turkeys
    Mar Costa-Hurtado
    Exotic and Emerging Avian Viral Diseases Unit, Southeast Poultry Research Laboratory, Agricultural Research Service, U, S, Department of Agriculture, Athens, GA, USA
    Vet Res 45:1. 2014
    ..These results suggest that infection with a heterologous virus may result in temporary competition for cell receptors or competent cells for replication, most likely interferon-mediated, which decreases with time. ..
  35. ncbi request reprint Development of a virosome vaccine for Newcastle disease virus
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 47:578-87. 2003
    ..These results demonstrate the potential of virosomes as an effective tool for ND vaccination...
  36. pmc H5N2 Highly Pathogenic Avian Influenza Viruses from the US 2014-2015 outbreak have an unusually long pre-clinical period in turkeys
    Erica Spackman
    Southeast Poultry Research Laboratory, USDA Agricultural Research Service, 934 College Station Rd, Athens, GA, 30605, USA
    BMC Vet Res 12:260. 2016
    ..Three isolates were selected for characterization in turkeys: the US index isolate from December 2014 (A/northern pintail/WA/40964/2014), and two poultry isolates from April 2015 (A/chicken/IA/13388/2015 and A/turkey/MN/12528/2015)...
  37. doi request reprint Lack of chicken adaptation of newly emergent Eurasian H5N8 and reassortant H5N2 high pathogenicity avian influenza viruses in the U.S. is consistent with restricted poultry outbreaks in the Pacific flyway during 2014-2015
    Kateri Bertran
    Exotic and Emerging Avian Viral Diseases Research Unit, Southeast Poultry Research Laboratory, U S National Poultry Research Center, Agricultural Research Service, U S Department of Agriculture, 934 College Station Rd, 30605 Athens, GA, USA Electronic address
    Virology 494:190-7. 2016
    ..Although these initial U.S. H5 HPAI viruses had reduced adaptation and transmissibility in chickens, multi-generational passage in poultry could generate poultry adapted viruses with higher infectivity and transmissibility. ..
  38. doi request reprint Measurement of avian cytokines with real-time RT-PCR following infection with the avian influenza virus
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, Athens, GA, USA
    Methods Mol Biol 436:127-34. 2008
    ..It is important to note that small nucleotide polymorphisms between different lines of birds may result in substandard results when using published primer and probe sequences. This requires empirical testing to ensure adequate results...
  39. pmc NP, PB1, and PB2 viral genes contribute to altered replication of H5N1 avian influenza viruses in chickens
    Jamie L Wasilenko
    Southeast Poultry Research Laboratory, USDA ARS, 934 College Station Road, Athens, GA 30605, USA
    J Virol 82:4544-53. 2008
    ..While the pathogenesis of AIVs in chickens is clearly dependent on the interaction of multiple gene products, we have shown that single-gene reassortment events are sufficient to alter the virulence of AIVs in chickens...
  40. doi request reprint Vaccine Protection of Turkeys Against H5N1 Highly Pathogenic Avian Influenza Virus with a Recombinant Turkey Herpesvirus Expressing the Hemagglutinin Gene of Avian Influenza
    Darrell R Kapczynski
    A Exotic and Emerging Avian Disease Research Unit, U S National Poultry Health Research Center, Agricultural Research Service, USDA, 934 College Station Road, Athens, GA 30605
    Avian Dis 60:413-7. 2016
    ..This study provides support for the use of a commercially available rHVT-AI vaccine to protect turkeys against H5N1 HPAI. ..
  41. pmc Impact of route of exposure and challenge dose on the pathogenesis of H7N9 low pathogenicity avian influenza virus in chickens
    Erica Spackman
    Southeast Poultry Research Laboratory, USDA Agricultural Research Service, 934 College Station Rd, Athens, GA 30605, USA Electronic address
    Virology 477:72-81. 2015
    ..Virus was shed at higher titers and spread to the kidneys in chickens inoculated by the intravenous route. Challenge experiments with three other human-origin H7N9 viruses showed a similar pattern of virus replication...
  42. doi request reprint Mucosal vaccination with a codon-optimized hemagglutinin gene expressed by attenuated Salmonella elicits a protective immune response in chickens against highly pathogenic avian influenza
    Karen A Liljebjelke
    Agricultural Research Service, USDA, Athens, GA 30605, USA
    Vaccine 28:4430-7. 2010
    ..Results provide evidence of effectiveness of attenuated Salmonella strains for delivery of recombinant avian influenza HA antigens and induction of mucosal and systemic immune responses protective against lethal challenge with HPAI...
  43. ncbi request reprint Production and characterization of monoclonal antibodies that react to the nucleocapsid protein of avian metapneumovirus subtype C
    Qingzhong Yu
    Southeast Poultry Research Laboratory, USDA Agricultural Research Service, 934 College Station Road, Athens, GA 30605, USA
    Avian Dis 50:419-24. 2006
    ..These MAbs provide new tools and methods for investigating aMPV infection and pathogenesis, as well as diagnosis of aMPV disease...
  44. pmc Nucleotide and predicted amino acid sequence-based analysis of the avian metapneumovirus type C cell attachment glycoprotein gene: phylogenetic analysis and molecular epidemiology of U.S. pneumoviruses
    Rene Alvarez
    Southeast Poultry Research Laboratory, Agricultural Research Service, U S Department of Agriculture, Athens, Georgia 30605, USA
    J Clin Microbiol 41:1730-5. 2003
    ..Epidemiologically, this indicates positive selection among U.S. isolates since the first outbreak of TRT in the United States...
  45. doi request reprint Evaluating the cell-mediated immune response of avian species to avian influenza viruses
    Darrell R Kapczynski
    Southeast Poultry Research Laboratory, US Department of Agriculture, Agricultural Research Service, Athens, GA, USA
    Methods Mol Biol 436:113-26. 2008
    ....
  46. doi request reprint Expression of H5 hemagglutinin vaccine antigen in common duckweed (Lemna minor) protects against H5N1 high pathogenicity avian influenza virus challenge in immunized chickens
    Kateri Bertran
    Southeast Poultry Research Laboratory, USDA ARS, 934 College Station Road, Athens, GA 30605, USA Electronic address
    Vaccine 33:3456-62. 2015
    ..Transgenic duckweed-derived HA could be a good alternative for producing high quality antigen for an injectable vaccine against H5N1 HPAI viruses...
  47. ncbi request reprint Sequence analysis of the S3 gene from a turkey reovirus
    Darrell R Kapczynski
    Agricultural Research Service, United States Department of Agriculture, Athens, Georgia 30605, USA
    Virus Genes 25:95-100. 2002
    ....