K M Trybus

Summary

Affiliation: Brandeis University
Country: USA

Publications

  1. pmc Spare the rod, spoil the regulation: necessity for a myosin rod
    K M Trybus
    Rosenstiel Research Center, Brandeis University, Waltham, MA 02254 9110, USA
    Proc Natl Acad Sci U S A 94:48-52. 1997
  2. ncbi request reprint The light chain-binding domain of the smooth muscle myosin heavy chain is not the only determinant of regulation
    K M Trybus
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    J Biol Chem 273:18423-8. 1998
  3. ncbi request reprint Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state
    R Dominguez
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02454 9110, USA
    Cell 94:559-71. 1998

Collaborators

Detail Information

Publications3

  1. pmc Spare the rod, spoil the regulation: necessity for a myosin rod
    K M Trybus
    Rosenstiel Research Center, Brandeis University, Waltham, MA 02254 9110, USA
    Proc Natl Acad Sci U S A 94:48-52. 1997
    ..If these interactions are prohibited under cellular conditions, unphosphorylated crossbridges can slowly cycle...
  2. ncbi request reprint The light chain-binding domain of the smooth muscle myosin heavy chain is not the only determinant of regulation
    K M Trybus
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02254 9110, USA
    J Biol Chem 273:18423-8. 1998
    ..The presence of the smooth muscle light chain-binding region and rod is therefore not sufficient to confer complete phosphorylation-dependent regulation upon all motor domains of the myosin family...
  3. ncbi request reprint Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state
    R Dominguez
    Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02454 9110, USA
    Cell 94:559-71. 1998
    ..A comparison of the lever arm positions in MDE-AIF4- and in nucleotide-free skeletal S1 shows that a potential displacement of approximately 10 nm can be achieved during the power stroke...