Marisa Wong Medina

Summary

Affiliation: Children's Hospital Oakland Research Institute
Country: USA

Publications

  1. ncbi request reprint The relationship between HMGCR genetic variation, alternative splicing, and statin efficacy
    Marisa Wong Medina
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Discov Med 9:495-9. 2010
  2. pmc Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism
    Marisa W Medina
    From the Children s Hospital Oakland Research Institute, CA M W M, F B, D N, E T, K S, R M K Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany J S, H R Sage Bionetworks, Seattle, WA L M M Section on Lipid Sciences, Department of Pathology, Wake Forest University Health Sciences, Winston Salem, NC L L R, R E T and Molecular Medicine Partnership Unit MMPU, Heidelberg, Germany C S, H R
    Arterioscler Thromb Vasc Biol 34:1917-23. 2014
  3. pmc Multivariate methods and software for association mapping in dose-response genome-wide association studies
    Chad C Brown
    Department of Statistics, North Carolina State University, Raleigh, NC, USA
    BioData Min 5:21. 2012
  4. pmc Alternative splicing in the regulation of cholesterol homeostasis
    Marisa W Medina
    Children s Hospital Oakland Research Institute, Oakland, CA 94609, USA
    Curr Opin Lipidol 24:147-52. 2013
  5. pmc RHOA is a modulator of the cholesterol-lowering effects of statin
    Marisa W Medina
    Children s Hospital Oakland Research Institute, Oakland, California, United States of America
    PLoS Genet 8:e1003058. 2012
  6. pmc The role of HMGCR alternative splicing in statin efficacy
    Marisa Wong Medina
    Children s Hospital Oakland Research Institute, CA 94609, USA
    Trends Cardiovasc Med 19:173-7. 2009
  7. pmc Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake
    Marisa Wong Medina
    Department of Atherosclerosis Research, Children s Hospital Oakland Research Institute, Oakland, California, United States of America
    PLoS ONE 6:e19420. 2011
  8. pmc Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin
    Lara M Mangravite
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Arterioscler Thromb Vasc Biol 30:1485-92. 2010
  9. pmc Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin
    Marisa Wong Medina
    Children s Hospital Oakland Research Institute, CA 94609, USA
    Circulation 118:355-62. 2008

Collaborators

Detail Information

Publications9

  1. ncbi request reprint The relationship between HMGCR genetic variation, alternative splicing, and statin efficacy
    Marisa Wong Medina
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Discov Med 9:495-9. 2010
    ....
  2. pmc Transmembrane protein 55B is a novel regulator of cellular cholesterol metabolism
    Marisa W Medina
    From the Children s Hospital Oakland Research Institute, CA M W M, F B, D N, E T, K S, R M K Institute of Human Genetics, University of Heidelberg, Heidelberg, Germany J S, H R Sage Bionetworks, Seattle, WA L M M Section on Lipid Sciences, Department of Pathology, Wake Forest University Health Sciences, Winston Salem, NC L L R, R E T and Molecular Medicine Partnership Unit MMPU, Heidelberg, Germany C S, H R
    Arterioscler Thromb Vasc Biol 34:1917-23. 2014
    ....
  3. pmc Multivariate methods and software for association mapping in dose-response genome-wide association studies
    Chad C Brown
    Department of Statistics, North Carolina State University, Raleigh, NC, USA
    BioData Min 5:21. 2012
    ..However, previous studies may have over-simplified the complex differences in dose-response profiles between genotypes, resulting in a loss of power...
  4. pmc Alternative splicing in the regulation of cholesterol homeostasis
    Marisa W Medina
    Children s Hospital Oakland Research Institute, Oakland, CA 94609, USA
    Curr Opin Lipidol 24:147-52. 2013
    ..In this review, we highlight recent studies examining alternative splicing as a modulator of cellular cholesterol homeostasis and as an underlying mechanism of dyslipidemia...
  5. pmc RHOA is a modulator of the cholesterol-lowering effects of statin
    Marisa W Medina
    Children s Hospital Oakland Research Institute, Oakland, California, United States of America
    PLoS Genet 8:e1003058. 2012
    ....
  6. pmc The role of HMGCR alternative splicing in statin efficacy
    Marisa Wong Medina
    Children s Hospital Oakland Research Institute, CA 94609, USA
    Trends Cardiovasc Med 19:173-7. 2009
    ....
  7. pmc Coordinately regulated alternative splicing of genes involved in cholesterol biosynthesis and uptake
    Marisa Wong Medina
    Department of Atherosclerosis Research, Children s Hospital Oakland Research Institute, Oakland, California, United States of America
    PLoS ONE 6:e19420. 2011
    ..Thus coordinated regulation of alternative splicing may contribute to cellular cholesterol homeostasis as well as plasma LDL levels...
  8. pmc Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin
    Lara M Mangravite
    Children s Hospital Oakland Research Institute, 5700 Martin Luther King Jr Way, Oakland, CA 94609, USA
    Arterioscler Thromb Vasc Biol 30:1485-92. 2010
    ..We tested the extent to which combined effects of common alleles of LDLR and HMGCR can contribute to this variability...
  9. pmc Alternative splicing of 3-hydroxy-3-methylglutaryl coenzyme A reductase is associated with plasma low-density lipoprotein cholesterol response to simvastatin
    Marisa Wong Medina
    Children s Hospital Oakland Research Institute, CA 94609, USA
    Circulation 118:355-62. 2008
    ..We hypothesized that HMGCR alternative splicing might be related to the interindividual variation in plasma low-density lipoprotein cholesterol response to statin treatment...